Newswise — Cernostics Inc., a biotechnology firm specializing in advanced cancer diagnostics, and Geisinger Health System, a $2.1 billion integrated health services organization, today announced a partnership in personalized healthcare. They will focus on developing diagnostic technologies to detect subtle differences in the cellular and molecular makeup of patient tissue samples. These technologies promise to more effectively predict disease progression and identify patients who are most likely to be receptive to specific cancer treatments.

Predictive and preventive, this personalized healthcare approach to cancer screening and treatment - utilizing multiplexed fluorescence microscopy and imaging technology - holds great potential to produce better, safer and more cost-effective results. It takes disease screening and treatment away from a “one size fits all” approach to emphasize an understanding of disease diversity and subtypes and, as a result, more effectively predict patients who will most likely benefit from specific cancer treatments, helping to avoid treatment without benefit and unnecessary costs.

The partnership combines Cernostics’ technological expertise in digital pathology and advanced tissue-based diagnostics with Geisinger’s robust, well-annotated MyCode™ biorespository and tumor bank, which is linked to its advanced electronic health records.

The agreement includes access to Geisinger pathology expertise and a clinical test bed to create and validate clinically driven pathology solutions. In addition, Geisinger clinical pathologists, oncologists and researchers will gain Cernostics’ expertise in sophisticated tissue microscopy. By optimizing their respective resources, the partnership will focus on developing cancer diagnostic tests that promise to increase quality and decrease costs, assess the safety of traditional cancer treatments and spur the creation of new cancer treatments.

“The very broad collaboration with Geisinger will provide a strong clinical drive to Cernostics. Our combined strengths put us in a unique position to address improvements in cancer patient diagnostics while at the same time integrating this new molecular-level information into a digital workflow of pathology and electronic health records. Support from Novitas and the Pittsburgh Life Science Greenhouse will provide funding for these important projects,” explained Michel Nederlof, Ph.D., President and Chief Technology Officer at Cernostics.

“This unique combination of Cernostics’ technology and key Geisinger assets will lead to a wave of innovation in cancer pathology and diagnostics that supports Geisinger’s vision for personalized healthcare,” noted Mike Hoerres, CEO, Cernostics, and Principal, Geisinger Ventures.

As part of this agreement, Cernostics completed a Series A financing round led by Novitas Capital (Wayne, Pa.), Geisinger Health System and the Pittsburgh Life Science Greenhouse (PLSG, Pittsburgh).

“Cernostics was founded as a spin-off of Cellumen Inc. in 2008 to apply predictive science to tissue-based diagnostics using panels of fluorescence-labeled biomarkers and informatics. We are pleased to join forces with Geisinger Health System, Novitas Capital and Pittsburgh Life Sciences Greenhouse,” noted D. Lansing Taylor, Ph.D., CEO of Cellumen Inc. and Chairman of Cernostics.

About Cernostics Inc.Cernostics is integrating quantitative pathology, advanced informatics and electronic medical record (EMR) management to create clinically-driven pathology solutions to improve individualized patient care. Cernostics focuses on TissueCipher Pathology (TCP™), a proprietary approach to integrating digital imaging pathology, highly multiplexed panels of fluorescence biomarkers, informatics and EMR systems for faster, better, less expensive pathology testing and improved individualized patient treatments. 570-214-6365. www.Cernostics.com

About Geisinger Health SystemGeisinger is a an integrated health services organization widely recognized for its innovative use of the electronic health record, and the development and implementation of innovative care models including advanced medical home and ProvenCare ("warranty") program. The system serves more than 2.6 million residents throughout 42 counties in central and northeastern Pennsylvania. www.geisinger.org About Novitas CapitalFounded in 1997, Novitas Capital (www.novitascapital.com) mines innovation and opportunities where investment for seed, start-up and early stage technology and life sciences ventures is scarce. Novitas discovers companies at their earliest stages, thoroughly vets them and, upon typically leading investment rounds, takes an active role in facilitating their success. Based in Wayne, Pennsylvania, Novitas currently has approximately 25 active portfolio companies and $237.5 million under management across three venture capital funds.

About Pittsburgh Life Science GreenhouseThe PLSG invests in and supports the growth of biosciences companies in western Pennsylvania. The PLSG has investment and business growth programs to increase the linkage between research, technology and commercialization; nurture and develop entrepreneurial biosciences enterprises; grow the region's talent pool in the life sciences; and help biosciences firms locate, expand or start-up in the region. www.plsg.com

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