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Shorter Radiation Use, BRCA Gene News, Staging Endometrial Cancer, and More in the Cancer News Source

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Food Additives, Facts About Wheat, Glowing Food Dye, and More in the Food Science News Source

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march for science, science advocacy, public outreach, Science Policy, American Society For Cell Biology, Earth Day

American Society for Cell Biology Officially Partners with March for Science Organizers

The American Society for Cell Biology (ASCB) recently signed an agreement officially lending its support to the national March for Science rally and teach-in in Washington, DC, scheduled for Earth Day, Saturday, April 22. ASCB was among the first to uphold the event’s mission to “unite the diverse universe of scientists and other community members in a non-partisan manner.”

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Rheumatoid Arthritis, RA, Rheumatoid Arthritis Remission, Rheumatoid Arthritis Medication, Autoantibodies, Autoimmune Disease And Disorder, B Cells, Tumor Necrosis Factor, anti-citrullinated protein antibodies, ACPA, Methotrexate

New Assay May Lead to a Cure for Debilitating Inflammatory Joint Disease

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Current treatments for rheumatoid arthritis relieve the inflammation that leads to joint destruction, but the immunologic defect that triggers the inflammation persists to cause relapses. Now the results of a new study suggest that clinical trials for new rheumatoid arthritis (RA) drugs should shift from their sole focus on relieving inflammation to eliminating the B cells that produce these antibodies.

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Ulcer, stomach bug, Helicobacter Pylori, Pathogen, Pathogen Evolution

Europeans Brought New Strains of Ulcer-Causing Bacterium to Pre-Columbian Americas

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Genome study shows mixing of European and African H. pylori strains in modern American populations.

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Glioblastoma, Brain Cancer, PGK1 enzyme, MD Anderson Cancer Center

Study Reveals PGK1 Enzyme as Therapeutic Target for Deadliest Brain Cancer

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Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic target for glioblastoma, an often fatal form of brain cancer, according to researchers at The University of Texas MD Anderson Cancer Center.

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Melanoma, Aging, adjuvant therapy

Anti-Aging Gene Identified as a Novel Promising Therapeutic Target for Older Melanoma Patients

Wistar scientists have shown an anti-diabetic drug can inhibit the growth of melanoma in older patients by activating an anti-aging gene that in turn inhibits a protein involved in metastatic progression and resistance to targeted therapies for the disease.

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Head And Neck Cancer, Immunotherapy, Immunotherapy Clinical Trials, head and neck squamous cell carcinoma

University Hospitals Seidman Cancer Center Enrolls First Patient in New National Head and Neck Cancer Study

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Story about the first patient enrolled in the new national phase I trial studying the side effects and best dose and schedule of pembrolizumab, an immunotherapy drug, when given together with chemotherapy and radiation therapy following surgery for very high risk head and neck cancer. Pembrolizumab is one of the first immunotherapy drugs.

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Water, states of water, supercooling, supercooled water, thermodynamic, Phases, water molecules, confined water, Margherita De Marzio, Gaia Camisasca, Maria Martin Conde, Mauro Rovere, Paola Gallo, Roma Tre University, The Journal Of Chemical Physics

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 28-Feb-2017 11:00 AM EST

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Aging, Dr. Nathan LeBrasseur, Idiopathic Pulmonary Fibrosis, Kogod Center on Aging, Medical Research, Minnesota News Release, news releases, Senescent cells

Mayo Clinic Researchers Discover Link Between Aging, Devastating Lung Disease

A Mayo Clinic study has shown evidence linking the biology of aging with idiopathic pulmonary fibrosis, a disease that impairs lung function and causes shortness of breath, fatigue, declining quality of life, and, ultimately, death. Researchers believe that these findings, which appear today in Nature Communications, are the next step toward a possible therapy for individuals suffering from idiopathic pulmonary fibrosis.

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New Night Frogs, Congo River Fish, Nigeria Highway is Dropped, and More in the Wildlife News Source

The latest research and features on ecology and wildlife.

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Flu Vaccines, Medical Curriculum Tailored to Native Americans, Tackling Heart Disease, and More in the Healthcare News Source

The latest research, features and announcements in healthcare in the Healthcare News Source

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Dermatology, Bacteriology, Immunology, Infectious Diseases, Microbiome

Transplanting Good Bacteria to Kill Staph

University of California San Diego School of Medicine researchers screened 10,000 colonies of bacteria found on the epidermis to determine how many had antimicrobial properties and at what rate these are found on healthy and non-healthy skin. In a paper published in Science Translation Medicine, the team reports isolating and growing good bacteria that produce antimicrobial peptides and successfully transplanting it to treat patients with the most common type of eczema, known as atopic dermatitis.

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Clinical Practice Guideline Focuses on Molecular Biomarker Testing for Patients with Colorectal Cancer

A new, evidenced-based clinical practice guideline on molecular biomarker testing for patients with colorectal cancer identifies opportunities for improving patient outcomes.

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Neurons, Motivation, Addiction, Decision Making, Cell Biology, Neuroscience

Researchers Uncover Brain Circuitry Central to Reward-Seeking Behavior

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UNC scientists found that as mice learn to associate a particular sound with a rewarding sugary drink, one set of prefrontal neurons becomes more active and promotes reward-seeking behavior while other prefrontal neurons are silenced, and those neurons act like a brake on reward-seeking.

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Cancer, Immunotherapy, CAR T cells, CRISP/Cas9, CRISPR, CAR T cell, Sloan Kettering, Memorial Sloan Kettering, Memorial Sloan Kettering Cancer Center, Michel Sadelain, Tumor, Cancer Research, genome editing, chimeric antigen receptor cells, chimeric antigen receptors

CAR T Cells More Powerful When Built With CRISPR, MSK Researchers Find

MSK researchers used the genome-editing tool CRISPR to create more potent chimeric antigen receptor (CAR) T cells that don't tire as easily when attacking cancer cells. The unexpected findings were published in the journal Nature on February 22 and underscore the potential of genome editing to advance immunotherapy for cancer.

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Sanford Researchers Take Broad Look at Stem Cells

Sanford Research scientists recently published a review article in an issue of Stem Cells Translational Medicine focused on the study of and utility of adult-derived stem cells.

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Bioengineer, tissue biofabrication, Cells, Tissues, Organs

University of Notre Dame Partners with the Advanced Regenerative Manufacturing Institute

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Researchers in bioengineering will join a consortium of academia, industry and government organizations and the nonprofit sector to develop next-generation manufacturing processes and technologies for cells, tissues and organs.

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Research On Retinal Pigment Epithelial (RPE) Cells Promises New Future Treatment for Glaucoma Patients

Scientific research builds its own momentum as one discovery triggers another, building an ongoing wave of unexpected possibilities. In the world of glaucoma, such a surge began when advances in stem cell research opened doors experts had never imagined.

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Kimmel Cancer Center, Gregg Semenza, Cancer, Chemotherapy

Scientists Identify Chain Reaction That Shields Breast Cancer Stem Cells From Chemotherapy

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Working with human breast cancer cells and mice, researchers at Johns Hopkins say they have identified a biochemical pathway that triggers the regrowth of breast cancer stem cells after chemotherapy.







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