Go here for the latest research, experts and features on Zika in the Zika Virus News Source
Mosquito bite sites are not just itchy, irritating nuisances - they also make viral infections spread by the insects far worse, new research has found.
A pathological and very complex autoimmune reaction of the skin": This is the definition doctors and scientists use to describe psoriasis, a disease that affects one to three percent of the population. It is characterised by accelerated cell division in the upper dermal layers with proliferated skin cells and an inflammation of the skin beneath. Many different cells are involved in the complex processes: skin cells (keratinocytes) and cells of the immune system, among others T lymphocytes, macrophages, mast cells and others.
A new study led by a Berkeley Lab scientist and UC Berkeley professor establishes for the first time copper’s role in fat metabolism, further burnishing the metal’s reputation as an essential nutrient for human physiology.
A new metastatic melanoma study suggests that a combination of two immunotherapies may be better than one: One treatment uses a patient’s own T cells modified in the lab to more powerfully recognize and attack tumors; The other treatment, a “checkpoint inhibitor,” releases the brakes on the body’s natural immune system.
In collaboration with Alexion Pharmaceuticals, Inc., scientists from Aarhus University have used X-rays to understand how the therapeutic antibody eculizumab prevents our immune system from destroying red blood cells and damaging kidney tissue.
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St. Jude Children’s Research Hospital investigators report promising preliminary results at the annual meeting of ASCO for an experimental monoclonal antibody when combined with chemotherapy for newly diagnosed patients.
Saint Louis University's article in "Trends in Immunology" explains why using a more accurate animal model could improve cancer research.
UofL dental researcher explores microbiological mechanisms as World Health Organization urges for a day of abstinence from tobacco use on May 31
Malnourished children are most likely to die from common infections, not starvation alone, and immune disorder may be part of the cause, according to a review led by Queen Mary University of London.
As part of its ongoing 25th Anniversary celebration, American Autoimmune Related Diseases Association (AARDA) announced today its May Autoimmune Heroes – private family foundations and individuals whose personal experience with autoimmune disease has led them to be incredible research fundraisers.
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Building on their groundbreaking research, Temple University scientists make another breakthrough in a potential cure for HIV.
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A major type of inflammatory bowel disease (IBD) may be caused in part by genetic variants that prevent beneficial bacteria in the gut from doing their job, according to a new study published today in the journal Science.
T cells use a kind of mechanical handshake, or tug test, to determine whether a cell they encounter is a foreign invader.
When It Comes to Spring Allergies, Oak Pollen More Potent Than Pine; Food Allergies of Low-Income Kids Are Poorly Managed; Flowers Not to Blame for Allergies, and More in the Allergies Channel
Pinellas County a Model for Mosquito-Borne Disease Surveillance, Scientists Unravel the Genetic Evolution of Zika Virus, Worm Infection Counters Inflammatory Bowel Disease and more in the Infectious Diseases News Source
Probiotic supplements protected female mice from the loss of bone density that occurs after having their ovaries removed, researchers at Emory University School of Medicine and Georgia State University have shown.
The addition of a house dust mite (HDM) sublingual allergen immunotherapy (SLIT) tablet to maintenance medications improved time to first moderate or severe asthma exacerbation during a period of inhaled corticosteroid (ICS) reduction among adults with HDM allergy-related asthma not well controlled by ICS, according to a study appearing in the April 26 issue of JAMA.
Evelo Biosciences and the University of Chicago have announced that they have entered into an exclusive worldwide license agreement to develop and commercialize a microbiome-based cancer immunotherapy.
While scientists have known for many years that there are cells living in the cavities surrounding various organs such as the heart, lung and liver, their function has remained unknown. A recent Cumming School of Medicine study examined these cells, and discovered they play an integral role in fast tissue repair. The study was published in the journal Cell this month.
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The April 19, 2016 issue of The Journal of the American Medical Association (JAMA) features an editorial by two Seattle Cancer Care Alliance (SCCA) medical oncologists who specialize in melanoma: Dr. Shailender Bhatia and Dr. John Thompson. Their editorial addresses the state of immunotherapy drugs, specifically PD-1 blockade, in the treatment of melanoma.
Women account for approximately half of all individuals living with HIV worldwide, and researchers wanted to identify the risk factors that increase susceptibility of women to genital infection.
Removing an immunomodulatory protein called osteopontin improves the symptoms of mice with muscular dystrophy by changing the type of macrophages acting on damaged muscle tissue, according to a paper published in The Journal of Cell Biology. The study, “Osteopontin ablation ameliorates muscular dystrophy by shifting macrophages to a pro-regenerative phenotype” by Joana Capote and colleagues, adds support to the idea that osteopontin inhibitors could be used to treat patients with Duchenne muscular dystrophy.
Dr. Sunil Hingorani, a member of the Clinical Research and Public Health Sciences divisions at Fred Hutchinson Cancer Research Center, will present recent groundbreaking developments in treating pancreas cancer with engineered T-cells at the American Association for Cancer Research Annual Meeting 2016 in New Orleans on April 16.
After a stroke, there is inflammation in the damaged part of the brain. Until now, the inflammation has been seen as a negative consequence that needs to be abolished as soon as possible. But, as it turns out, there are also some positive sides to the inflammation, and it can actually help the brain to self-repair.
Mass. General study confirms the safety of allergy shots, calls into question proposed changes in preparation standards.
Newly identified mechanism may offer ways to enhance the immune response to fight cancer or strengthen long-term protection provided by vaccines
Researchers have found antibodies to the newly discovered influenza D virus in pigs, cattle, horses, goats and sheep, but not poultry. South Dakota State University doctoral student Chithra Sreenivasan has proven that the guinea pig can be used as an animal model and is developing a way to study the virus in living cells—trachea and lung epithelial cells from swine and cattle.
Ludwig Cancer Research and the Cancer Research Institute (CRI) have launched a Phase 1/2 clinical trial of combination immunotherapy for advanced ovarian cancer. The international, multicenter trial is led by George Coukos, director of the Ludwig Institute for Cancer Research, Lausanne and Brad Monk, director of Gynecologic Oncology at St. Joseph’s Hospital and Medical Center.
Award-winning journalist Rita Baron-Faust and renowned lupus researcher, Dr. Jill Buyon, republishes updated "Autoimmune Connection: Essential Information for Women on Diagnosis, Treatment and Getting on with Your Life".
Researchers have identified a common variant in a non-coding RNA that may contribute to the intestinal inflammation that occurs in people with celiac disease. The findings point to a possible new risk factor for developing celiac disease in people with celiac disease risk genes.
Renewing a commitment to advance its reputation in lung cancer and other thoracic malignancies, NYU Langone Medical Center has announced the appointment of physician-scientist Leena Gandhi, MD, PhD, as director of thoracic medical oncology at its Laura and Isaac Perlmutter Cancer.
TESARO, Inc., an oncology focused biopharmaceutical company, and the Institute for Applied Cancer Science at The University of Texas MD Anderson Cancer Center today announced an exclusive collaboration to discover and develop small molecule product candidates against undisclosed immuno-oncology targets.
The closely related Hendra and Nipah viruses (referred to jointly as henipaviruses) are deadly cousins of the more common mumps, measles, and respiratory syncytial viruses, all members of the paramyxovirus family. Henipavirus outbreaks are on the rise, but little is known about them, partly because research has to be conducted under extreme level containment conditions.
American Autoimmune Related Diseases Association Salutes Autoimmune Heroes: Kellie Martin, Haley Ramm and Barbara Ramm
The most common immune disorder, common variable immunodeficiency disorder (CVID), is notoriously difficult to diagnose early, before serious complications develop. Genetic analysis of six families from across the U.S. and Europe has revealed that mutations in IKAROS, known for its central role in immune cell development, define a new class of CVID. Published in the New England Journal of Medicine, the results open the door to personalized health care tailored to patients with this disorder.
Recently discovered biomarkers may provide valuable new approaches to monitoring immunosuppressive drug therapy in organ transplant recipients—with the potential for individualized therapy to reduce organ rejection and minimize side effects, according to a special article in the April issue of Therapeutic Drug Monitoring, official journal of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. The journal is published by Wolters Kluwer.
St. Jude Children’s Research Hospital scientists have identified a mechanism that might explain the link between maternal infections during pregnancy and cognitive problems in children; findings may impact clinical care.
A new study from scientists at The Scripps Research Institute describes the high-resolution structure of the HIV protein responsible for recognition and infection of host cells. The studyis the first to show this HIV protein, known as the envelope (Env) trimer, in its natural or “native” form.
A study by researchers at the University of Southampton and Southampton General Hospital, is the first to assess the prevalence of two different types of food hypersensitivity and the risk factors associated with them.
St. Jude Children’s Research Hospital scientists have discovered that an enzyme antibiotics rely on to kill bacteria also promotes survival of pneumococcus and sets the stage for serious, invasive infections
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