A multidisciplinary team led by Scott Rodeo, MD, and Christopher Mendias, PhD, at Hospital for Special Surgery (HSS) has been awarded the Orthopaedic Research and Education Foundation (OREF) Clinical Research Grant in Cellular Therapy.
An international team of researchers led from Karolinska Institutet have, in experiments on mice, pinpointed a mechanism for the conversion of energy-storing white fat into energy-expending brown fat. The study is published in the Journal of Experimental Medicine.
A team of researchers in Italy and Austria has determined that a drug approved to treat chronic lymphocytic leukemia (CLL) may be less effective in a particular subset of patients. The study, which will be published January 4 in the Journal of Experimental Medicine, reveals that ibrutinib has a diminished capacity to delocalize and kill tumor cells expressing an adhesive protein called CD49d, but combining ibrutinib treatment with drugs that block CD49d activation could prevent the tumor cells from sheltering in lymphoid organs.
Some materials have the unique ability to self-assemble into organized molecular patterns and structures. Materials scientist Gregory Doerk of the Electronic Nanomaterials Group at the Center for Functional Nanomaterials (CFN)—a U.S. Department of Energy (DOE) Office of Science User Facility at Brookhaven National Laboratory—takes advantage of this ability in materials called block copolymers.
Researchers at the University of Pennsylvania have discovered how the Pacific midshipman fish can hum continuously for up to an hour in order to attract potential mates. The study, which is featured on the cover of the January 2018 issue of the Journal of General Physiology, explains how the muscle fibers surrounding the fish’s swimbladder can sustain the high rates of contraction—up to 100 times per second—that are needed to produce the animal’s distinctive call.
Blacks and Hispanic very preterm infants are more likely to be born at New York City hospitals with higher risk-adjusted neonatal morbidity-mortality rates, and these differences contribute to excess morbidity and mortality among black and Hispanic infants. These differences in hospital of birth explained 39.9% of the black-white disparity and 29.5% of the Hispanic-white disparity in outcomes.
Mount Sinai researchers have discovered a new drug combination that could provide the first targeted therapy for some of the deadliest cancers, as well as molecular predictors of tumor response to the therapy, according to a study published in Cell Reports in January.
Mount Sinai researchers have discovered that normal immune cells called macrophages, which reside in healthy breast tissue surrounding milk ducts, play a major role in helping early breast cancer cells leave the breast for other parts of the body, potentially creating metastasis before a tumor has even developed, according to a study published in Nature Communications.
NYU’s Arthur L. Carter Journalism Institute’s First Amendment Watch, an online resource offering coverage and context to the debate over freedom of expression, dives inside the Pentagon Papers, whose publication led to a press crisis culminating in a landmark 1971 Supreme Court decision. The case is the centerpiece of the recently released film “The Post,” starring Meryl Streep and Tom Hanks.
NEW YORK (December 21, 2017) — A group of scientists now considers a little-known dolphin that only lives along the Atlantic coasts of Western Africa to be among the continent’s most endangered mammals, a list that includes widely recognized species such as gorillas, African wild dogs, and black rhinos, according to WCS (Wildlife Conservation Society) and the IUCN’s (International Union for Conservation of Nature) Cetacean Specialist Group.
The American Thoracic Society Foundation has announced that 16 researchers have been awarded unrestricted research grants totaling more than $1 million to advance pulmonary, critical care and sleep medicine around the world. These one-year, $40,000 grants can be used to support basic science, patient-oriented, and public health research.
Researchers in Italy have discovered how specific versions of a protein called Numb protect the key tumor suppressor p53 from destruction. The study, which will be published December 21 in the Journal of Cell Biology, suggests that the loss of these particular Numb proteins makes breast cancers more aggressive and resistant to chemotherapy, but points the way toward new therapeutic approaches that could improve patient outcome by preserving p53 levels.
Teng of the University of New Hampshire brings his research to design new types of nanostructured materials for energy conversion and storage applications to Brookhaven Lab’s Center for Functional Nanomaterials (CFN).
Treating a liver disease called NASH (non-alcoholic steatohepatitis) is difficult. Now scientists believe they have found a pharmacologic approach that may inhibit NASH, and thus stop deadly conditions that result from NASH.
NYU President Andrew Hamilton and Provost Katherine Fleming today announced the appointment of Rangarajan “Raghu” Sundaram as Dean of the Leonard N. Stern School of Business.
Sunil Agrawal, professor of mechanical engineering and of rehabilitation and regenerative medicine at Columbia Engineering, working with Movement Disorders faculty from the department of neurology at Columbia University Medical Center, find that a single session of perturbation-based training, using their Tethered Pelvic Assist Device, increased stability of patients during walking while exposed to unexpected perturbations. (Scientific Reports)
Varenicline, one of the most commonly prescribed drugs for helping people quit smoking, may put them at higher risk for a cardiovascular event, according to new research published online in the American Journal of Respiratory and Critical Care Medicine.
Many cancer cells are relatively sensitive to the deprivation of an essential amino acid known as methionine. Now, a Ludwig Cancer Research study published in the journal Science Signaling and led by Alex Toker, an investigator in the Ludwig Center at Harvard, has elucidated one mechanism behind that dependency.
An interdisciplinary research team led by the National University of Singapore (NUS) has recently discovered a unique panel of urine biomarkers that could accurately diagnose nephrolithiasis, also commonly known as kidney stone.
We tend to overstate our negative feelings and symptoms in surveys, shows a new study by a team of psychology researchers. This bias wears off over time, but the results point to the possibility that measurements of health and well-being, which are vital in making medical assessments and in guiding health-related research, may be misinterpreted.
The larvae of the fish that live in coral reefs look alike, making it difficult for marine biologists to study reef populations. Now, Weizmann's Prof. Rotem Sorek found a way to “barcode” 80% of fish species known to visit the reefs in a Red Sea gulf.
Dennis S. Charney, MD, Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai and President for Academic Affairs at Mount Sinai Health System, has been named a Fellow of the National Academy of Inventors (NAI).
A team of researchers has isolated the characteristics of bots on Twitter through an examination of bot activity related to Russian political discussions.
UPTON, NY— As scientists have explored the structure and properties of matter at ever deeper levels they’ve discovered many exotic new materials, including superconductors that carry electric current with no resistance, liquid crystals that align to produce brilliant dynamic displays, and materials exhibiting various forms of magnetism.
Knowing that individuals with insomnia are also unlikely to change their ways, researchers from Columbia University Medical Center tested a method to reduce the adverse effects of evening ambient light exposure, while still allowing use of blue light-emitting devices. Their findings will be published in the January issue of Journal of Psychiatric Research.
Chemical Engineering Prof Daniel Esposito has developed a novel photovoltaic-powered electrolysis device that can operate as a stand-alone platform that floats on open water. His floating PV-electrolyzer can be thought of as a “solar fuels rig” that bears some resemblance to deep-sea oil rigs--but it would produce hydrogen fuel from sunlight and water instead of extracting petroleum from beneath the sea floor. (International Journal of Hydrogen Energy)
Children exposed to coarse particulate matter may be more likely to develop asthma and to be treated in an ER or be hospitalized for the condition, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
Phillips School of Nursing (PSON) at Mount Sinai Beth Israel has received a Nursing Workforce Diversity grant totaling approximately $800,000 from the U.S. Health Resources and Services Administration (HRSA).
The Dubin Breast Center of The Tisch Cancer Institute at the Mount Sinai Health System held its sixth annual benefit on Monday, December 11, 2017, at the Ziegfeld Ballroom in Manhattan.
Scientists have come up with a way to massively speed up the ordering process for self-assembling materials. The resulting ultra-small, well-ordered patterns could be used in the fabrication of microelectronics, antireflective surfaces, magnetic data storage systems, and fluid-flow devices.
The Solar Energy Research Institute of Singapore (SERIS) at the National University of Singapore (NUS) has reached a new cell efficiency milestone in the development of its low-cost screen-printed bifacial monoPoly silicon solar cell technology, recording an average cell efficiency of 21.5% in pilot-scale production using commercially available large-area Cz-Si wafers.
Researchers from the Mechanobiology Institute, Singapore at the National University of Singapore, report that endocytosis, which was previously thought to be a random process, actually occurs in a coordinated manner through collective dynamics. The work, led by Assistant Professor Wu Min, showed how a major endocytic pathway mediated by the protein clathrin, was found to commence with periodic traveling waves of clathrin, which were coupled temporally and spatially to downstream cortical actin waves. Clathrin endocytic waves were identified here as the upstream initiator of cortical actin waves.
A Stony Brook University research team is developing a new type of PIR sensor that is equipped with an electronic shutter and other technologies that enable fast and accurate occupancy detection including individuals who are stationary.
Conservationists and partners with the Bengaluru-based Wildlife Conservation Society (WCS) -India received multiple awards at the Sanctuary Wildlife Awards event held in Mumbai yesterday. The awardees included Mr. Jayachandran S, Mr. Shashank Dalvi, Mr. Nikit Surve and Ms. Vaishali Rawat.
Researchers at Columbia Engineering, experts at manipulating matter at the nanoscale, have made an important breakthrough in physics and materials science, recently reported in Nature Nanotechnology. Working with colleagues from Princeton and Purdue Universities and Istituto Italiano di Tecnologia, the team has engineered “artificial graphene” by recreating, for the first time, the electronic structure of graphene in a semiconductor device.
New York University’s Hagop Kevorkian Center for Near Eastern Studies is hosting “The Great Gig in the Sky: Imagining the Soundtrack to Utopia,” a multi-media exhibition by Lebanese band Mashrou’ Leila that envisions fictitious historical moments, through Jan. 27, 2018.
Thanks to the generosity of the Stavros Niarchos Foundation, the Pediatric Heart Center at the Children’s Hospital at Montefiore (CHAM) is opening the John H. Gutfreund Fetal Heart Program at the Montefiore Hutchinson Campus.
A new book co-edited by tiger biologist Dr. Ullas Karanth of (WCS) Wildlife Conservation Society and Dr. James Nichols, an Emeritus statistical ecologist from the United States Geological Survey (USGS), provides an authoritative text on monitoring tigers, their prey, and many other similarly endangered species.
A diverse group of engineers, urban planners, data scientists, policymakers, and others came to New York to discuss how to build resilience into urban interconnected critical infrastructure.
This past weekend brought fierce Santa Ana Winds to Southern California that are expected to last all week. As of this writing, major fires are burning in Ventura County and other areas within Los Angeles County. The South Coast Air Quality Management District lists the following areas of direct smoke impacts: ftp://ftp.aqmd.gov/pub/globalist/Advisory2.pdf
NewYork-Presbyterian and Walgreens are collaborating to bring convenient access to NewYork-Presbyterian’s world-class care through new telemedicine services, now available through Walgreens digital properties and at self-service kiosks at select Duane Reade drugstores in New York.
Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells’ chromatin. The study, which will be published December 11 in the Journal of Cell Biology, suggests that targeting this enzyme could make pancreatic cancer cells more vulnerable to existing therapies that currently have only limited effect against this deadly form of cancer.