Recent updates in evidence-based recommendations have led to changes in the use of steroid and hyaluronic acid injection for patients with osteoarthritis of the knee, reports a study in the May 16, 2018 issue of The Journal of Bone & Joint Surgery. The journal is published in partnership in the Lippincott portfolio by Wolters Kluwer.
Cancer, like so many other overwhelming or life-altering situations, can really stick with a person. For many, the end of treatment is met with a flood of emotions that can make it difficult to get back to normal life. Learning how to recognize and live with a cancer diagnosis is a struggle that can last for years even after being given a clean bill of health. For Penn patient Catherine Hagele, the end of treatment was simply the end of one chapter in her journey, and the beginning of another.
For patients with sepsis, a serious infection causing widespread inflammation, immediate treatment is essential to improve the chances of survival. An updated “Hour-1 Bundle” of the international, evidence-based guidelines for treatment of sepsis is introduced in the June issue of Critical Care Medicine. The official journal of the Society of Critical Care Medicine (SCCM), Critical Care Medicine is published in the Lippincott portfolio by Wolters Kluwer.
A targeted therapy that has shown its power in fighting ovarian cancer in women including those with BRCA1 and BRCA2 mutations may also help patients with aggressive pancreatic cancer who harbor these mutations and have few or no other treatment options. An international team of researchers led by the Perelman School of Medicine and the Basser Center for BRCA at the University of Pennsylvania reported their findings this week in JCO Precision Oncology.
Given the complex and rapidly evolving health care system in the United States, medical schools must focus their efforts on training more physician leaders to master the diverse skills needed to navigate emerging challenges in the field, urge leaders from the Perelman School of Medicine at the University of Pennsylvania in a new Perspective piece published today in the New England Journal of Medicine.
National Comprehensive Cancer Network collaborates with the Caribbean Association for Oncology & Hematology to create NCCN Harmonized Guidelines for the Caribbean
The battle between the human immune system and long-term, persisting infections and other chronic diseases such as cancer results in a prolonged stalemate. Over time battle-weary T cells become exhausted, giving germs or tumors an edge. Using data from multiple molecular databases, researchers have found nine distinct types of exhausted T cells, which could have implications for fighting chronic infections, autoimmunity, and cancer.
For veterans undergoing surgery in the VA healthcare system, homelessness is an important risk factor for unplanned hospital readmission, reports a study in the June issue of Medical Care, published in the Lippincott portfolio by Wolters Kluwer.
National Comprehensive Cancer Network releases NCCN Guidelines for Patients: AML
Charles Ryan, a distinguished international financier who started one of Eastern Europe’s leading venture capital firms, has been appointed to the Temple University Board of Trustees.
Pediatric researchers have found that children and adults treated with some oral antibiotics have a significantly higher risk of developing kidney stones. This is the first time that these medicines have been linked to this condition. The strongest risks appeared at younger ages and among patients most recently exposed to antibiotics.
By integrating data on the function of essential metabolic enzymes with genetic, protein, and metabolic abnormalities associated with “clear cell” renal cell carcinoma (ccRCC), researchers have determined that enzymes important in multiple pathways are universally depleted in ccRCC tumors.
Different Parkinson’s-related brain disorders are characterized by misfolded proteins embedded in cells. Researchers found that the type of brain cell afflicted dictates which pathological form of α-synuclein protein becomes the disease culprit.
Recent advances in scientific understanding of how posttraumatic stress disorder (PTSD) develops and persists may lead to more effective treatment and even prevention of this debilitating disorder, according to the May/June special issue of Harvard Review of Psychiatry, published by Wolters Kluwer.
A technique of magnetic stimulation of the brain can increase walking speed in patients who are undergoing rehabilitation after a stroke, reports a research update in the American Journal of Physical Medicine & Rehabilitation, the official journal of the Association of Academic Physiatrists. The journal is published by Wolters Kluwer.
When the Centers for Medicare and Medicaid Services (CMS) announced controversial policies inviting states to establish work requirements as a condition to receive Medicaid, many in the medical community opposed it. If these measures continue to be approved – as is the case in Kentucky, Indiana, and Arkansas – CMS should act to minimize the potential harms they could cause to Medicaid recipients, two Penn Medicine experts in law and ethics argue in a new JAMA Viewpoint published this week, that lays out basic safeguards to help guide the states. “Promoting health, after all,” the authors note, “is the goal of Medicaid.”
The Melanoma Research Foundation is honoring two Penn clinicians for their tireless work in caring for patients.
For patients with substance use disorders seen in the emergency department or doctor's office, locating and accessing appropriate treatment all too often poses difficult challenges. Healthcare providers and treatment facility administrators share their views on delays and obstacles to prompt receipt of substance use disorder treatment after referral in a study in the Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine (ASAM). This journal is published in the Lippincott portfolio by Wolters Kluwer.
Over forty percent of all older adults in the United States are living with four or more chronic illnesses, receive care from a fragmented health care system, and are struggling with rising costs and uneven quality. To confront this national crisis, more than fifty health system leaders, policy makers, innovators, and scholars convened last week to identify actionable recommendations designed to transform care delivery for older adults with complex health and social needs and support their family caregivers.
Jameer Nelson, the all-time leading scorer in Saint Joseph's men's basketball history and NBA All-Star, is among the graduates participating in SJU's 167th commencement exercises.
Wolters Kluwer Health announced today it has been named publisher of the Porto Biomedical Journal (PBJ) and will begin publishing the title under its Lippincott portfolio with Volume 3, Issue 1. The bimonthly open access journal publishes research conducted in the biomedical fields.
With unprecedented demographic trends leading to an aging workforce, a new emphasis on productive aging is needed to keep US workers of all generations as healthy and productive as possible, according to an article in the May Journal of Occupational and Environmental Medicine.
A review of nearly 500 cases of infants with severe congenital hyperinsulinism who underwent partial or near-total removal of their pancreas for persistent hypoglycemia at Children’s Hospital of Philadelphia (CHOP) showed that surgeons can cure virtually all patients with the focal, or localized, form of the rare genetic disease.
Over 150 experts from Children’s Hospital of Philadelphia (CHOP) will travel to Toronto for this year’s Pediatric Academic Societies (PAS) Meeting.
Parents of twins and other multiple-birth children experience higher than average rates of depression, anxiety and other mental health issues, particularly during the first three months, according to a survey study in the May issue of Journal of Psychiatric Practice. The journal is published by Wolters Kluwer.
James Eberwine, PhD, the Elmer Holmes Bobst Professor of Systems Pharmacology and Translational Therapeutics is part of an international team of researchers, who will receive $1.25M over the next three years to better understand oxidative phosphorylation (OxPhos), a biological system that plays a key role in the production of energy, generation of free radicals, and cell death.
A new National Science Foundation grant awarded to Professor of Statistics Steve Wang will help him, his students, and a recent alumna decode why the Earth may be entering a modern extinction.
PHILADELPHIA — Penn Medicine has been named #6 on magazine’s annual “Best Employers in America” list ranking large employers across the nation, up from #7 in 2017. Other organizations listed in the top ten include Google, Trader Joe’s, and the Michelin Group, placing Penn Medicine among some of the most prominent companies in the nation – and first both in Pennsylvania and among all health care employers.
College of Education Professor Sara Goldrick-Rab has won a prestigious Andrew Carnegie Fellowship for her scholarship and activism in food and housing insecurity among college students.
After eight years of failed treatment for persistent atrial fibrillation (AF), Janet Szilagyi, 78 of Clayton, New Jersey, became the first patient in the United States to undergo cardiac ablation – a procedure in which an electrophysiologist will scar or destroy tissue in the heart that’s allowing incorrect electrical signals to cause an abnormal heart rhythm – using an intraoperative imaging and mapping system recently cleared by the Food and Drug Administration (FDA).
Faculty members in Boyer College of Music and Dance and the College of Liberal Arts won prestigious Guggenheim Fellowships to pursue research.
Lee O’Neill, MBA, has been appointed as the new Director for Finance & Administrative Services for the Monell Chemical Senses Center, effective May 1, 2018. He succeeds John K.T. Tran, MS, CRA, who is retiring after serving 30 years as Monell’s Finance Director.
The Garrison Lecturer is a scholar distinguished for contributions to medical history or other fields of science and learning, who presents original and previously unpublished research in a lecture given at the American Association for the History of Medicine’s (AAHM) annual meeting.
Visualizing the signals that make brain cells connect reveals new insights into the developing brain.
NCCN and MPN Research Foundation present Know What Your Doctors Know: Myeloproliferative Neoplasms (MPN), a free webinar for experts to provide information and answer questions on diagnosis and treatment options.
Penn Medicine performed the first robot-assisted spinal surgery in a three-part, two-day procedure. The robotic arms made it possible for the multidisciplinary team at Penn to successfully remove a rare tumor from the patient's neck, where the skull meets the spine.
The U.S. Food and Drug Administration (FDA) has expanded approval for a personalized cellular therapy developed at the University of Pennsylvania’s Abramson Cancer Center, this time for the treatment of adult patients with relapsed or refractory large B-Cell lymphoma after two or more lines of systemic therapy. Today’s approval includes treatment of diffuse large B-cell lymphoma (DLBCL) – the most common form of non-Hodgkin’s lymphoma – as well as high grade B-cell lymphoma and DLBCL arising from follicular lymphoma.
A CAR-T-based immunotherapy successfully kills tumors and prevents metastatic growth, in final preclinical tests before human trials.
Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia (CLL) don’t respond to chimeric antigen receptor (CAR) T cell therapy, and the answer is tied to how primed patients’ immune systems are before the therapy is administered.
PHILADELPHIA – Susan Brozena, MD, FACC, FAHA, an emeritus associate professor of Cardiovascular Medicine in the Perelman School of Medicine at the University of Pennsylvania, received the 2018 Lifetime Achievement Award from the American Heart Association. This award celebrates a professional who has had a pioneering career and has made an exceptional impact on their patients, the Philadelphia community and the field of cardiology.
Patients who’ve suffered from traumatic brain injuries (TBIs) have changes in tiny blood vessels in their brains that researchers believe are linked to a range of cognitive symptoms, according to new findings presented at the 2018 AAN Annual Meeting. The findings may help doctors pinpoint specific types of TBIs and tailor personalized therapies.
Hearing is an important part of fitness-for-duty assessments of police officers and other public safety professionals – but standard hearing tests don't give a true picture of whether these professionals can hear and communicate in the specific "noise environments" where they must work. A new approach to hearing assessment in public safety officers − which has been adopted by five government agencies in the United States and Canada − is presented in an article in Ear and Hearing. The official journal of the American Auditory Society, Ear and Hearing is published by Wolters Kluwer.
Wistar and Ben Franklin Technology Partners of Southeastern Pennsylvania (Ben Franklin), a nonprofit conglomerate of partners providing direct/seed funding, mentorship and networks to strengthen enterprise development, have signed a Memorandum of Understanding (MoU) to accelerate the advancement of early-stage life sciences start-ups coming out of Wistar.
Good cosmetic results are an important factor – but not the only factor – differentiating positive versus negative reviews for plastic surgeons on Google, Yelp, and other online review sites, according to a special topic paper in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Most studies evaluating platelet-rich plasma (PRP) injection for facial rejuvenation and other cosmetic procedures have reported positive results, according to a critical review in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
PHILADELPHIA – Two biostatisticians from the Center for Clinical Epidemiology and Biostatistics and professors of Biostatistics in Biostatistics and Epidemiology Mingyao Li, PhD, and Sharon Xie, PhD, have been elected fellows of the American Statistical Association, the largest professional organization for statisticians in the United States.
This award will support Casey Greene's work on the Human Cell Atlas, a global effort to map every type of cell in the human body as a resource for investigating health and disease.
Penn Medicine researchers have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer – and they’ve also proven they have a way to see that feature using PET imaging.
In March 2017, the U.S. Food and Drug Administration approved ocrelizumab as the first treatment for both relapsing (RMS) and progressive forms of multiple sclerosis (MS), a genetic disease that afflicts approximately 400,000 Americans with an estimated 10,000 new cases every year. This week at the 2018 American Academy of Neurology (AAN) Annual Meeting in Los Angeles, Penn Medicine neurologist Amit Bar-Or, MD, FRCPC, chief of the Multiple Sclerosis division and director for the Center for Neuroinflammation and Experimental Therapeutics, presented findings from two studies that look more deeply into the impact of ocrelizumab in these patients.
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