Feature Channels: Asthma

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RNA sequencing and machine learning applied to develop new asthma biomarker

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A new study in Annals of Allergy, Asthma and Immunology shows that a greater desire by older asthma patients for involvement in medical decision-making was associated with a better quality of life

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Children living in neighborhoods that are not conducive to walking are more likely to develop asthma and to continue to have this condition through later childhood, according to a new study published in the Annals of the American Thoracic Society.

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Vaccinating asthmatic pre-schoolers against influenza could dramatically reduce their risk of being hospitalized after an attack, Canadian researchers find.

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The latest research and features in cell biology in the Cell Biology News Source

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Some cancers express unusually high levels of a neural calcium channel known as the ‘wasabi receptor,’ which plays a role in detecting pain, cold and other sensations. New research finds cancer cells co-opt this neural channel to increase their tolerance against toxic oxidative stress.

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An article published in Annals of Allergy, Asthma and Immunology shows allergies can have serious, far-reaching consequences, especially on adolescent sufferers.

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In a new study, researchers found significant associations between seniors’ long-term exposure to two types of air pollution and hospitalization for acute respiratory distress syndrome (ARDS). The study was presented at the 2018 American Thoracic Society International Conference.

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A new discovery about how the immune system responds to common sinus infections and asthma could explain why patients develop these issues in the first place and ultimately may lead to improved targeted therapies.

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Administering antibiotics to adults hospitalized with an asthma exacerbation without any documented indication of lung infection appears to lengthen hospital stay, increase cost and result in increased risk for antibiotic-related diarrhea, according to new research presented at the ATS 2018 International Conference.

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Palliative care appears to reduce the risk of suicide in veterans diagnosed with advanced stage lung cancer, according to new research presented at the ATS 2018 International Conference.

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Two new studies of patients with difficult-to-control asthma show that the eczema drug dupilumab alleviates asthma symptoms and improves patients’ ability to breathe better than standard therapies. Dupilumab, an injectable anti-inflammatory drug, was approved in 2017 by the Food and Drug Administration as a treatment for eczema, a chronic skin disease.

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A type of flavonoid found in dark-pigmented fruits like red grapes and blueberries may slow the lung function decline that occurs with aging, according to new research presented at the ATS 2018 International Conference.

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Exposure to elevated levels of carbon monoxide (CO) in utero increases infants’ risk of poor lung function at one month after birth, according to new research conducted as part of the Ghana Randomized Air Pollution and Health Study (GRAPHS). While household air pollution from solid fuel stoves has previously been associated with child mortality, this is the first study to investigate the association between household air pollution and lung development beginning in utero and to identify the most harmful times during pregnancy for exposure to this pollution. The study was presented at the 2018 American Thoracic Society International Conference.

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long-term study of the health of Canadian children has found that exposure to ozone (O3), a common air pollutant, at birth was associated with an 82 percent increased risk of developing asthma by age three. The study, which was a 10-year follow-up to the 2006 Toronto Child Health Evaluation Questionnaire (T-CHEQ), was presented at the 2018 American Thoracic Society International Conference.

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People with mild asthma are often prescribed a daily treatment regimen, but up to 80 per cent do not follow the routine, using inhalers only when they have an asthma attack. Now the researchers have found an as-needed combined-drug inhaler is a viable treatment option.

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Rutgers New Jersey Medical School and collaborators from Shanghai University in China examined more than 6,000 compounds and identified a drug that relaxes the muscles and opens the airways, allowing those with asthma to breathe. Find out why this new therapy might give people a better option and new hope.

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The latest research, experts and features in Public Health in the Public Health News Source

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In a new analysis of interviews conducted with children who have asthma, their caregivers and their clinicians, Johns Hopkins researchers found that there was significant lack of agreement about why the kids miss their needed daily anti-inflammatory medication.

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Click here to go to the Food Science News Source

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Even the briefest increase in airborne fine particulate matter PM2.5, pollution-causing particles that are about 3 percent of the diameter of human hair, is associated with the development of acute lower respiratory infection (ALRI) in young children, according to newly published research. Increases in PM2.5 levels also led to increased doctor visits for these lung infections.

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Some of what you think are allergy symptoms could be signs of asthma.

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Click here for the latest research and features on Children's Health.

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Click here to go directly to Newswise's Obesity News Source

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As the winter cold season melts into seasonal spring allergies, many people may start to experience sneezing, wheezing and other breathing difficulties. Sometimes, the trouble goes away after a few days, but if it lingers or recurs, asthma could be the culprit.

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Two-thirds of surveyed caregivers felt that their child’s food allergy affected their own daily lives very much or extremely, according to a report in the Annals of Allergy, Asthma and Immunology. Two-thirds of caregivers also expressed significant fear that their child would have an allergic reaction to food. Despite this fear, the majority of caregivers were eager to enroll their child in a clinical trial for immunotherapy, which involves giving the child a gradually increasing dose of the food allergen under close supervision in order to train the immune system to not react to that food. Only 8 percent of caregivers responded that they would not enroll their child in this type of clinical trial.

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Children with mild to moderate asthma do not benefit from a common practice of increasing their inhaled steroids at the first signs of an asthma exacerbation, according to clinical trial results published in The New England Journal of Medicine. Researchers found short-term increases in inhaled steroids did not prevent attacks in children aged 5 to 11, and may even slow a child’s growth.

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A new study shows that pregnant women and new moms aware of the 2017 guidelines on early introduction of peanuts to prevent allergy are still hesitant to put them in place. And not everyone has heard about them.

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Working with mice, Johns Hopkins researchers report they have found previously known skin itch receptors in the airways that appear to contribute to bronchoconstriction and airway hypersensitivity, hallmarks of asthma and other respiratory disorders. The investigators’ experiments in mice suggest that the receptors’ activation directly aggravates airway constriction and—if the same process is active in people—may be a promising new target for the development of drug therapies.

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A special receptor on cells that line the sinuses, throat and lungs evolved to protect mammals from developing a range of allergies and asthma, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

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Asthma is a chronic inflammatory disease driven by the interplay of genetics, environmental factors and a diverse cast of immune cells. In their latest study, researchers at La Jolla Institute for Allergy and Immunology (LJI) identified a subset of T cells, whose frequency serves as early childhood immune signature that predicts the risk of developing asthma later on.

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Women who work as cleaners or regularly use cleaning sprays or other cleaning products at home appear to experience a greater decline in lung function over time than women who do not clean, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

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Women with asthma who only use short-acting asthma relievers take longer to become pregnant than other women, according to international research led by the University of Adelaide.

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5 tips from the American College of Allergy, Asthma and Immunology for parents who’d like to send their child with allergies or asthma to summer camp, and still keep them safe.

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LJI researchers report mechanisms used by a subgroup of ILCs, known as ILC2 cells, to undergo maturation required for them to mount an effective immune response. These discoveries suggest a novel approach to treat inflammatory disease caused by overactive ILC2s.

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Nuisance pest into medically important threat? A North Carolina State University study shows that histamine levels are substantially higher in homes infested by bed bugs than in pest-free homes, and that these histamine levels persist for months – even if the bed bugs have been eliminated from the home.

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UC San Diego celebrates the launch of the Krupp endowment at the new Centers for Integrative Health, thanks to Richard N. Krupp’s philanthropic legacy, which may be realized at over $30 million in the coming years.

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Houston Methodist researchers have a new explanation for what causes the lungs’ airways to close during asthma attacks. The researchers who published the study in the Feb. 5 issue of the Journal of Experimental Medicine note that the discovery holds promise for developing a new class of drugs different from the steroids currently used to treat asthma.

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Leaders from the community and health system celebrate with ribbon cutting and open house.

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Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide. The tiny molecule can change how proteins function. But new research featured in Molecular Cell suggests supplementing nitric oxide—NO—is only the first step. Researchers have discovered previously unknown enzymes in the body that convert NO into “stopgap” molecules—SNOs—that then modulate proteins. The newly discovered enzymes help NO have diverse roles in cells. They may also be prime therapeutic targets to treat a range of diseases.

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Romance is the name of the game on Valentine’s Day, and keeping sneezing, wheezing and watery eyes out of the mix helps put everyone more in the mood for love. Here are five tips from ACAAI to help make your Valentine’s Day special.

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Asthma costs the U.S. economy more than $80 billion annually in medical expenses, missed work and school days and deaths, according to new research published online in the Annals of the American Thoracic Society.

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A Michigan State University researcher is providing new insight into how certain types of stress interact with immune cells and can regulate how these cells respond to allergens, ultimately causing physical symptoms and disease.

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A newly published Atopic Dermatitis (AD) Yardstick from the American College of Allergy, Asthma and Immunology has practical recommendations for physicians about the treatment of AD.

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Asthma affects almost 1 in 10 children in the U.S. and is a leading cause of emergency room visits and hospitalizations in preschoolers. According to new research from Duke Health and collaborators, symptoms may be worse for children ages 2 to 5 who are overweight.

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An updated practice parameter from the Joint Task Force on Practice Parameters stresses that people with egg allergy should receive their yearly flu shot, and that no special precautions are required.

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Tomorrow, ministers at the 15th ministerial council meeting of the Energy Community in Kosovo will adopt new rules for emission limits for coal power plants in the Western Balkans (as part of the transposition of the EU’s Industrial Emissions Directive into national law).

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Researchers at The Johns Hopkins University report statistical evidence that children exposed to airborne coarse particulate matter — a mix of dust, sand and non-exhaust tailpipe emissions, such as tire rubber — are more likely to develop asthma and need emergency room or hospital treatment for it than unexposed children.