Un estudio de Mayo Clinic no descubrió ninguna evidencia respecto a que los niños a quienes se les administra anestesia antes del tercer cumpleaños tengan menos coeficiente intelectual que aquellos que no la reciben.
The research team analyzed muscle biopsies of young adults with and without Type 1 diabetes who exceed Diabetes Canada's recommended weekly levels for physical activity. The researchers found structural and functional changes in the power generation parts of the cell, or mitochondria, of those with diabetes. Not only were the mitochondria less capable of producing energy for the muscle, they were also releasing high amounts of toxic reactive oxygen species, related to cell damage.
ROCHESTER, Minn. – A Mayo Clinic study finds no evidence that children given anesthesia before their third birthdays have lower IQs than those who did not have it. A more complex picture emerges among people who had anesthesia several times as small children: Although their intelligence is comparable, they score modestly lower on tests measuring fine motor skills, and their parents are more likely to report behavioral and learning problems. The findings are published in Anesthesiology
Investigators at Cedars-Sinai are exploring a new way to treat amyotrophic lateral sclerosis (ALS) by transplanting specially engineered neural cells into the brain. Their new study shows the transplanted cells delayed disease progression and extended survival in animal models.
People with obesity are more likely to develop a rapid and irregular heart rate, called atrial fibrillation, which can lead to stroke, heart failure and other complications, according to Penn State researchers.
An international team led by Argonne National Laboratory makes breakthrough in understanding the chemistry of the microscopically thin layer that forms between the liquid electrolyte and solid electrode in lithium-ion batteries. The results are being used in improving the layer and better predicting battery lifetime.
Evidence suggests that developing cooking and food preparation skills is important for health and nutrition, yet the practice of home cooking is declining and now rarely taught in school. A new study published in the Journal of Nutrition Education and Behavior found that developing cooking skills as a young adult may have long-term benefits for health and nutrition.
This month’s issue of the journal Molecular & Cellular Proteomics features research using novel proteomics methods to address unanswered questions in cancer research, including protein variation within tumors; the failure of a candidate cancer drug; and how a chemotherapeutic combination acts synergistically.
Can medical marijuana help to fight the opioid epidemic? Many believe that it can. But a new study finds that people who use medical marijuana actually have higher rates of medical and non-medical prescription drug use—including pain relievers. The study appears in the Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine (ASAM), published by Wolters Kluwer.
Researchers at the UC Davis MIND Institute have found that children with autism spectrum disorder (ASD) have reduced immune system regulation, as well as shifts in their gut microbiota. The immune deregulation appears to facilitate increased inflammation and may be linked to the gastrointestinal issues so often experienced by children with ASD. The research was published in the journal Brain, Behavior, and Immunity.
UC San Diego biologists have created the world’s first gene drive system—a mechanism for manipulating genetic inheritance—in Drosophila suzukii, an agricultural pest that has invaded much of the United States and caused millions of dollars in damage to high-value berry and other fruit crops.
This new insight may allow researchers to design drugs that improve immune responses to vaccines.
Newly publicized audiovisuals support full species status for one of the dancing birds-of-paradise in New Guinea.
Hotspots of type 1 diabetes in New York City are found in food swamps, areas with a higher proportion of fast food restaurants, for children and adults with type 1 diabetes, according to a new study published in the Endocrine Society’s Journal of the Endocrine Society.
Washington University School of Medicine in St. Louis and Epharmix, a digital health company, have created a new automated text messaging service that may curb opioid abuse and prevent relapse. Patients receive text messages to gauge if they’re feeling OK or struggling with potential relapse. Patients also can activate a panic button to request immediate help.
Ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) alone or in combination with acetaminophen are better at easing dental pain than opioids, according to new research conducted with the School of Dental Medicine at Case Western Reserve University.
Dairy farmers use antibiotics to keep their herds healthy and production high. At the same time, these treatments threaten to harm public health through the creation of antibiotic-resistant bacteria. While the full impact of such antibiotics on humans is not completely understood, a new Cornell University study has pinpointed the financial toll that eliminating antibiotic use would have on dairy farms, a finding that could help guide regulatory policy.
Researchers at University of California San Diego School of Medicine have determined that psychological resilience has a positive effect on health outcomes for people living with schizophrenia. This is the first study to quantitatively assess the effects of both childhood trauma and psychological resilience on health and metabolic function in people living with schizophrenia. The findings are published in the April 17 online issue of the Journal of Clinical Psychiatry.
New research from experts in history, computer science and cognitive science shines fresh light on the French Revolution, showing how rhetorical and institutional innovations won acceptance for the ideas that built the French republic's foundation and inspired future democracies.
A new experimental study from the University of Nebraska-Lincoln has found that administering a naturally produced hormone to pinyon jays can increase food sharing among the highly social species.
Studying mice, researchers have found that a drug called nalfurafine hydrochloride (Remitch) can deliver itch relief by targeting particular opioid receptors on neurons in the spinal cord. The new study suggests that the drug may be effective against many types of chronic itching that don’t respond to conventional drugs such as antihistamines.
Theoretical physicists used simulations to explain the unusual readings collected in 2009 by the Mercury Surface, Space Environment, Geochemistry, and Ranging mission. The origin of energetic electrons detected in Mercury’s magnetic tail has puzzled scientists. This new study, appearing in Physics of Plasmas, provides a possible solution to how these energetic electrons form.
Machine learning algorithms excel at finding complex patterns within big data, so researchers often use them to make predictions. Researchers are pushing the technology beyond finding correlations to help uncover hidden cause-effect relationships and drive scientific discoveries. At the University of South Florida, researchers are integrating machine learning techniques into their work studying proteins. As they report in The Journal of Chemical Physics, one of their main challenges has been a lack of methods to identify cause-effect relationships in data obtained from molecular dynamics simulations.
Each year, the effects of corroding materials sap more than $1 trillion from the global economy. As certain alloys are exposed to extreme stress and temperatures, an oxide film begins to form, causing the alloys to break down even more quickly. What precisely makes these conditions so conducive for corrosion, however, remains poorly understood, especially in microelectromechanical devices. Chinese researchers have started to chip away at why these materials corrode under mechanical stress; they describe their work in the Journal of Applied Physics.
Despite universal newborn screening that detects the presence of sickle cell trait (SCT), only 16 percent of Americans with SCT know their status. To address this issue, in Ohio, in-person education is offered to caregivers of referred infants with SCT.
Scientists who participated in the South Java Deep Sea Biodiversity Expedition 2018 (SJADES 2018) had collected more than 12,000 creatures during their 14-day voyage to survey the unexplored deep seas off the southern coast of West Java, Indonesia.
The U.S. Food and Drug Administration granted approval to the combination of two immunotherapy drugs, ipilimumab and nivolumab, for the treatment of metastatic kidney cancer.
In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich’s ataxia (FA), a widely used cholesterol-lowering drug increased a precursor of HDL (high-density lipoprotein), the “good cholesterol.” Decreased HDL and ApoA-l levels in the general population are associated with an increased risk of death from cardiomyopathy and heart failure. Researchers found the FA patients had serum ApoA-I levels lower than healthy control subjects.
• When RAS genes mutate, they generate proteins that cause cells to proliferate uncontrollably • Researchers use ‘top-down proteomics’ to characterize intact proteins isolated from colorectal cancer cell lines and tumors • By understanding precisely how proteins change in cancer, researchers open door for new targets for treatment
A simple, one-page form given to patients ahead of their doctor visit can significantly improve satisfaction with the care they receive, according to a study by Duke Health researchers.
Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in children. Scientists report in the journal Molecular Cancer Therapeutics testing the small molecule 6-thio-2’deoxyguanosine (6-thio-dG) in brain cancer stem cells derived from tumor cells donated by patients. Researchers also tested the treatment in humanized mouse models of pediatric brain cancer.
Researchers at the South Australian Health and Medical Research Institute (SAHMRI) and the University of Adelaide have discovered a faster, more cost-effective way to determine which DNA mutations cause human bowel cancer.
Junk food ads are shown more frequently on TV at times when many children are watching, new Heart Foundation-funded research shows.
Tune in today for a webcast of the 3rd annual NIGMS Director’s Early-Career Investigator Lecture where Dr. Jeramiah Smith, an assistant professor at the University of Kentucky, will describe how his research on the sea lamprey is shedding light on cancer biology, tissue regeneration, and vertebrate evolution.
To get a closer look at prevalence and age-related trends of osteoarthritis, rheumatoid arthritis and other types of arthritis in the U.S., a study examined nationally representative data from 43,706 participants aged 20 years and older, turning up some unexpected findings.
Computer-aided surgery facilitates complete cancer removal for difficult pelvic tumors
Most of the roughly 15.5 million cancer survivors in the U.S. receive chemotherapy, and roughly 65 percent develop some degree of the chemotherapy-induced nerve damage known as peripheral neuropathy.
New research from a team of scientists at McMaster University suggests that brief exercise breaks during lectures can help university students focus their attention, retain information and improve overall learning.
A team of researchers from Lawrence Livermore National Laboratory (LLNL), Princeton University, Johns Hopkins University and the University of Rochester have provided the first experimentally based mass-radius relationship for a hypothetical pure iron planet at super-Earth core conditions. This discovery can be used to evaluate plausible compositional space for large, rocky exoplanets, forming the basis of future planetary interior models, which in turn can be used to more accurately interpret observation data from the Kepler space mission and aid in identifying planets suitable for habitability.
According to a new report by researchers at the UCLA Fielding School of Public Health, approximately 78,400 children in the U.S. are or have been married.
Roughly one in 10 women in the United States will experience depression, according to the Centers for Disease Control and Prevention. The consequences, however, may extend to their children, report researchers at University of California San Diego School of Medicine, who found that a mother’s depression can negatively affect a child’s cognitive development up to the age of 16. The findings are published in the April issue of Child Development.
Giving opioids to rats to quell pain after surgery prolongs pain for more than three weeks and primes specialized immune cells in the spinal cord to be more reactive to pain, according to a new University of Colorado Boulder study
Childhood poverty cost $1.03 trillion in 2015, about 5.4 percent of the gross domestic product of the United States, according to a new study from the Brown School at Washington University in St. Louis.“Impoverished children grow up having fewer skills and are thus less able to contribute to the productivity of the economy,” said Mark Rank, noted wealth inequality researcher.
Using chemotherapy along with aptamers -- lab-made molecules that function like antibodies -- Duke Health researchers showed that they can zero in on and kill prostate cancer tumors in mice while leaving healthy tissue unscathed.
UNC School of Medicine scientists led by Nikolay Dokholyan add to evidence that small aggregates of SOD1 protein are the brain-cell killing culprits in ALS, but the formation of larger, more visible, and fibril-like aggregates of the same protein may protect brain cells.
Being an “evening person” is linked to higher body mass indices among people with Type 2 diabetes, and having breakfast later in the day seems to be what drives this association, according to a new paper in the journal Diabetic Medicine.Obesity is common among people with Type 2 diabetes. Having an evening preference — waking up later and going to bed later — has been linked to an increased risk for obesity, but research is lacking regarding this phenomenon among people with Type 2 diabetes.
A landmark 2016 Cleveland Clinic study of widely used pain-relieving drugs showed that celecoxib (Celebrex) was associated with comparable cardiovascular safety and better gastrointestinal and kidney safety when compared with either naproxen (Naprosyn) and ibuprofen (Motrin). A new substudy, published today in the Journal of the American College of Cardiology, analyzed outcomes in PRECISION based on the presence or absence of aspirin use with specific NSAIDs (nonsteroidal anti-inflammatory drugs).
Researchers have found that increasing land clearing for logging in Solomon Islands–even with best management strategies in place – will lead to unsustainable levels of soil erosion and significant impacts to downstream water quality.
A new text alert system is helping fishermen avoid Atlantic sturgeon accidentally caught when searching for other species. Fishermen receive a text showing areas and water depths Atlantic sturgeon are most likely to be found, allowing them to avoid the vulnerable species when targeting other fish.
UCLA-led research finds that internet search terms and tweets related to sexual risk behaviors can predict when and where syphilis trends will occur.
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