Focus: Hidden - LA Metro

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In a two-year study at UCLA, nearly two-thirds of people with advanced melanoma responded positively to a treatment that combines the immunotherapy drug pembrolizumab with a herpes virus called talimogene laherpareovec, or T-VEC. Researchers led by Dr. Antoni Ribas found that the treatment's side effects were manageable, and comparable to side effects for people who took either pembrolizumab or T-VEC as a standalone treatment.

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USC Information Sciences Institute's John Heidemann tracks internet outages as they hit Southeast Texas

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The grant provides support for an innovative clinical trial that seeks to compare outcomes for young patients with newly diagnosed severe aplastic anemia – comparing the use of unrelated-donor blood and marrow transplant to immune suppression therapy.

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Females tend to report more symptoms—and more severe ones--and may also take longer to recover from brain injuries than their male counterparts.

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To understand metastasis, Yves DeClerck, MD, of Children’s Hospital Los Angeles has studied the tumor microenvironment for his entire career. He has recently been awarded $2.2 million from the National Cancer Institute, to investigate the microenvironment from a relatively new context.

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Max Martin, Hans Zimmer, Jack Antonoff and the Chainsmokers announced as honorees for Songs of Hope XIII — benefiting City of Hope.

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A new report, released today, examined portrayals of computer science across media. The results demonstrate that while the uses of tech may seem to be unfettered, there are still limits as to who can be shown on screen using computer science.

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Each fall, parents pack their college freshmen off to school, fingers crossed for a solid start on the road to adulthood. But some students don’t find their footing and return home after a semester or two to regroup.

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Brief interventions in a primary care clinic can reduce patients’ risky substance use by 4.5 days per month — a 40 percent decline among the Latino patients surveyed — compared with people who did not receive the brief intervention.

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Study finds no one does well with less than seven hours of sleep; more than 11 hours suboptimal, too

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USC Norris Comprehensive Cancer Center is the first site actively recruiting for a clinical trial researching a new, gentle, automated technology for imaging dense breasts.

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For young women heading off to college, it can be a time filled with the excitement of living away from home. This new sense of independence should also include taking charge of one’s own health.

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CSU Fullerton psychology professor Dr. Allen Gottfried has spent nearly 40 years researching different types of giftedness and how this trait helps kids develop into successful adults.

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Earning a mark of excellence from one of the health care industry's top surveying bodies, Children's Hospital Los Angeles (CHLA) has been accredited by CARF International for its pediatric inpatient medical rehabilitation programs.

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Twin brothers Bader and Mohammed Alhathal took first place for best undergraduate student technical paper at the 2017 Institute of Industrial and Systems Engineers (IISE) Global Conference in Philadelphia, following their win at the Western Regional IISE Conference in Oregon.

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The Southern California Consortium for Technology and Innovation in Pediatrics (CTIP), based at Children's Hospital Los Angeles, has awarded $165,000 in seed grants to accelerate projects specifically designed to improve the safety and delivery of care to infants and children.

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Doctors, pharmacists and other healthcare professionals are heading back to school at Cedars-Sinai, joining the first class of a new, accredited master’s degree program in health delivery science, offering an advanced curriculum focused on measuring and improving the value of healthcare.

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Researchers successfully used a gene that suppresses cholesterol levels as part of a treatment to reduce plaque in mice with a disorder called familial hypercholesterolemia. In a preclinical study, researchers found that the gene, LeXis, lowered cholesterol and blockages in the arteries, and the treatment appeared to reduce the build-up of fat in liver cells.

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Cancer treatments have many effects on patients – some apparent and some less so. One of the most noticeable changes is a change in taste.

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Still uses the NMR spectrometer to conduct his research on plant extracts he procured from the National Cancer Institute (NCI) Active Repository Program.

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Keck Medicine of USC has appointed Dr. Santhi Iyer Kumar as its first chief quality and patient safety officer.

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Researchers use fMRI to compare neural responses to food cues in both overweight and lean adolescents and observe that adolescents at an increased risk for obesity had less neural activity in areas of the brain responsible for self-regulation and attention.

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The California Pre-Doctoral program supports the doctoral aspirations of students in the CSU to increase diversity within the pool of university faculty.

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More than 80 percent of women living with a history of breast or ovarian cancer at high-risk of having a gene mutation have never taken the test that can detect it.

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From nitrogen-infused coffee to vending machines that sell hot java, these entrepreneurs — all made in the CSU — are disrupting a $40 billion business.

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Cedars-Sinai neuroscience investigators have found that Alzheimer’s disease affects the retina – the back of the eye – similarly to the way it affects the brain. The study also revealed that an investigational, noninvasive eye scan could detect the key signs of Alzheimer’s disease years before patients experience symptoms.

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Cedars-Sinai is bolstering an ongoing effort to strengthen the social safety net in the Los Angeles region with a third year of grants — totaling $4,827,930 — to programs that address the physical and mental healthcare needs of many underserved populations, including the homeless, at-risk youth, immigrants and others.

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Brit Wigintton has been named the 2017–18 recipient of the Sony Pictures Entertainment (SPE) Fellowship at USC Annenberg.

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Recent research has shown a direct correlation between excessive smartphone usage and unhappiness with kids and teens. Children's Hospital Los Angeles psychologist Stephanie Marcy discusses the issue and provides tips for parents on how to manage their kids' device activity.

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Women who have gone through menopause and who have been using a vaginal form of estrogen therapy do not have a higher risk of cardiovascular disease and cancer than women who have not been using any type of estrogen.

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Muller Fabbri, MD, PhD, of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles, has been awarded $1.9 million by the National Cancer Institute of the NIH to further his research on neuroblastoma.

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In leading the Language Acquisition Resource Center at San Diego State, Dr. Mary Ann Lyman-Hager has made the teaching of language — from French and Spanish to Pashto and Dari — her life’s mission.

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UCLA researchers have developed a new approach that could eventually help young people respond better to treatment for acute lymphoblastic leukemia. The scientists discovered in mice that when the production of nucleotides -- also known as the building blocks of life -- is stopped, a "DNA replication stress response" is activated. The replication stress response is a cellular monitoring system that usually senses and resolves DNA damage, but instead allows cancer cells to survive. The team, led by Dr. Caius Radu, a member of UCLA's Jonsson Comprehensive Cancer Center, used results of the study to devise a three-drug combination treatment regimen, which has proven to kill cancer cells and eradicate acute lymphoblastic leukemia in mouse models.

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UCLA researchers have discovered a new way to activate the stem cells in the hair follicle to make hair grow. The research, led by scientists Heather Christofk and William Lowry, may lead to new drugs that could promote hair growth for people with baldness or alopecia, which is hair loss associated with such factors as hormonal imbalance, stress, aging or chemotherapy treatment.

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Cardiac stem cell infusions could someday help reverse the aging process in the human heart, making older ones behave younger, according to a new study from the Cedars-Sinai Heart Institute.

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Dr. Richard Addante is five days into a 45-day stay in a simulated space shuttle that will allow researchers to measure the psychological effects of extended isolation in space.

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It is that time of year for kids returning to school to get vaccinated before the school year starts. But the controversy over the HPV vaccine continues to rage as it has since its introduction in the U.S. in 2014.

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A routinely used hospital tool can predict which liver transplant recipients are more likely to do poorly after surgery, according to a study led by Cedars-Sinai. The findings could help doctors identify which patients should receive physical therapy or other targeted interventions to improve their recovery.

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Watching transgender characters on fictional TV shows has the power to influence attitudes toward transgender people and policy issues.

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Investigators at Children's Hospital Los Angeles have succeeded in better defining a rare pediatric malignant liver disease — a necessary step in achieving an optimum treatment.

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The Keck School of Medicine of USC is actively recruiting Hispanics with multiple sclerosis to participate in a study examining the impact of genetics, acculturation and cultural perceptions on disease severity.

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UCLA Health hospitals in Westwood and Santa Monica placed No. 1 in Los Angeles, No. 2 in California and No. 7 in the nation in the 2017–18 U.S. News and World Report rankings. “UCLA Health is proud to be recognized for providing world-class treatment to patients from greater Los Angeles, across the state and around the globe,” said Johnese Spisso, president of UCLA Health, CEO of UCLA Hospital System and associate vice chancellor of UCLA Health Sciences.

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Cedars-Sinai Medical Center has been named to the “Honor Roll” in U.S. News & World Report’s “Best Hospitals 2017-18,” earning a place among 20 U.S. hospitals to receive the designation. The medical center also had 12 medical specialties nationally ranked in the magazine’s newest hospital rankings released Tuesday.

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Is California prepared to meet the specialized healthcare needs of the next generation of teens? According to the American Board of Pediatrics, there are only 51 physicians in California who are board-certified in Adolescent Medicine. A team of investigators at CHLA is working to bridge this gap.

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Policy changes include expanded use of multiple measures for course placement in the first year, the elimination of non-credit bearing prerequisite courses and a revamped Early Start Program that provides students college credit.

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Intensive academic advising may prove to be a game-changer when it comes to helping students stay on track to earning a degree.

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An experimental treatment derived from a potentially deadly microorganism may provide lifesaving help for kidney transplant patients, according to an international study led by investigators at Cedars-Sinai. The study found that treating patients with the drug IdeS® before transplantation significantly reduced, and in most cases eliminated, donor-specific antibodies that can cause rejection or failure of the new organ.

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Sarcoma is a rare and deadly form of cancer occurring in the bones and connective tissue that affects individuals of all ages. Its aggressiveness, rarity and diversity continue to hinder efforts to identify effective therapies for people with this malignancy. Patient-derived orthotopic xenografts (PDOX) are unique models where a patient’s individual tumor is grown in mice. Such xenografts have long shown great promise in modeling how sarcoma and other cancers can respond to and resist therapies, but their feasibility for use in individual patients in clinical settings remains unknown.

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A new study from the USC Viterbi School of Engineering’s Signal Analysis and Interpretation Lab (SAIL)--which creates automatic tools for signal analysis and linguistic assessment --uncovers how media communicates about gender, race and age finding that in the majority of films, females roles are not central to the plot.