UCLA researchers have received a $13 million grant from the National Institutes of Health to find new ways to overcome melanoma resistance to some of the most promising targeted therapies and immunotherapies.
New research finds that tattooed skin does not sweat as much as non-inked areas of the body, which may have implications for the body’s ability to cool in people with extensive tattooing.
Scientists are planning for Phase 1 human trials of a vaccine they developed by using CRISPR gene-editing technology to mutate the parasite that causes leishmaniasis, a skin disease common in tropical regions of the world and gaining ground in the United States.
Dermatology researchers at Henry Ford Health System, in collaboration with a team at the University of Michigan, have demonstrated that certain N95 respirators tainted with COVID-19 can be effectively and safely decontaminated for reuse using ultraviolet-C light (UV-C), a method commonly utilized for treating rare skin diseases.
Researchers say the outside and inside of the facemasks were decontaminated in a prototype phototherapy unit that dispenses a UV-C dosing level high enough to effectively kill the virus in less than two minutes while still preserving the facemask’s breathability, fit and overall integrity.
The American Academy of Dermatology has named board-certified dermatologist Iltefat H. Hamzavi, MD, FAAD, a Patient Care Hero for his innovative use of light therapy to sanitize masks needed by frontline health care workers.
The American Academy of Dermatology has named board-certified dermatologist Esther Freeman, MD, PhD, DTM&H, FAAD, a Patient Care Hero for developing an international registry that tracks the many ways COVID-19 manifests itself through the skin.
Commercials from pharmaceutical companies advertising medication to treat psoriasis and eczema lack people from racial and ethnic minorities, according to research from the Perelman School of Medicine at the University of Pennsylvania.
A new article published online in the Journal of the American Academy of Dermatology reveals just how common these illicit products are on popular e-commerce sites, increasing the public’s risk for severe and potentially long-term complications, including blindness, disfiguration, and stroke.
Patients on immunosuppressive therapy for common skin and rheumatic diseases like psoriasis and rheumatoid arthritis are not at increased risk for contracting COVID-19 and should continue taking their medicine as prescribed, say Henry Ford Health System dermatology researchers in a study published in the Journal of the American Academy of Dermatology. Most of these patients are not at any greater risk for COVID-19 than the general population, despite their weakened immune system.
UCLA researchers shed light on how interferon-gamma (IFN-y) guides the treatment response in people with advanced melanoma who are treated with one of the leading immunotherapies — immune checkpoint blockade.
Acne affects up to 50 million Americans. For people with skin of color, acne is often accompanied by dark spots or patches called hyperpigmentation. Dermatologists from the American Academy of Dermatology say there are plenty of things people with skin of color can do at home to help clear their acne.
Researchers at the George Washington University have found that the hair loss drug spironolactone is not associated with increased risk of female breast cancer recurrence and may be safe to treat female pattern hair loss in breast cancer survivors. Their findings are published in the Journal of the American Academy of Dermatology.
Because of the COVID-19 pandemic, masks have become the new normal. While wearing a mask in public is crucial, it can take a toll on your skin. The good news is there are several ways to prevent and treat acne and irritation caused by frequent face masking usage, also known as "maskne."
In a new article published in the Journal of Investigative Dermatology, Moffitt researchers identify erythropoietin-producing hepatocellular receptor A2 (EphA2) as a driver of metastasis and BRAF-MEK inhibitor resistance in melanoma.
As the coronavirus continues to spread throughout the country, many people may find themselves spending more time outdoors for a much-needed change of scenery. While gardening, hiking in the woods and swimming can provide relief amid continuous social distancing measures, dermatologists from the American Academy of Dermatology say the increased exposure to things like sunlight, insects and poisonous plants can cause some itchy and painful rashes. Fortunately, there are a few simple steps people can take to avoid unwanted rashes and other skin issues while still enjoying the outdoors.
Before lathering on the sunscreen and heading outdoors, it's important to know the signs of heat-related injuries and how to stay cool when the temperatures soar.
If you are noticing red, irritated skin or small pimples under your face mask, you are far from alone. Allison Truong, MD, a board-certified dermatologist with Cedars-Sinai Medical Group, says she is now seeing many patients complaining of what's commonly being called "maskne," or mask-acne.
With so many sunscreens out there, how do you know which one is effective—and safe—for your child? Dr. Minnelly Lu, pediatric dermatologist at Children's Hospital Los Angeles, shares the latest advice.
A consensus statement published today in JAMA Dermatology by a group of melanoma researchers evaluates the use of prognostic genetic expression profiling within clinical treatment of patients with melanoma. The group cautioned against routine use of currently-available genetic expression profiling tests for patients with cutaneous melanoma.
The American Academy of Dermatology (AAD) has named board-certified dermatologists Hon Pak, MD, FAAD, MBA, and Darryl Hodson, MD, FAAD, as Patient Care Heroes for their work launching the country’s first robust teledermatology project two decades ago.
Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy. The research will be published online today in the Journal of Allergy and Clinical Immunology.
While the majority of parents recognize the importance of sunscreen, they may not always use best practices to protect children from getting burned, a new national poll suggests.
A UCLA-led study has found that dermatopathologists, who specialize in diagnosing skin diseases at the microscopic level, are motivated both by patient safety concerns and by malpractice fears — often simultaneously — when ordering multiple tests and obtaining second opinions, with a higher proportion of these doctors reporting patient safety as a concern.
When ordering additional microscopic tests for patients, 90% of the dermatopathologists surveyed cited patient safety as a concern and 71% of them reported malpractice fears. Similarly, when obtaining second reviews from a consulting pathologist or recommending additional surgical sampling, 91% cited safety concerns and 78% malpractice concerns.
A new 10-year analysis led by Igor Puzanov, MD, MSci, FACP, Director of Early Phase Clinical Trials and Chief of Melanoma at Roswell Park Comprehensive Cancer Center and published today in the journal JAMA Oncology provides new insights into an important question: whether BRAF V600E/K mutation status or previous BRAF inhibitor (BRAFi) therapy with or without a MEK inhibitor (MEKi) affects response to pembrolizumab (brand name Keytruda) in patients with advanced melanoma.
Researchers at the Icahn School of Medicine report that roflumilast cream (ARQ-151), which contains a highly potent, selective phosphodiesterase-4 (PDE4) inhibitor demonstrated significant improvements in patients with psoriasis signs and symptoms in as early as two weeks. The phase 2b trial results showed that when patients with plaque psoriasis applied topical roflumilast once-daily they reported clear skin as well as improvement in itch and burden of disease. The results of the paper were published online today in The New England Journal of Medicine.
The Journal of the American Academy of Dermatology is the top peer-reviewed journal in its field, according to the 2019 impact factor rankings recently published by the Journal Citation Reports (JCR) Web of Science Group.
The Dr. Philip Frost Department of Dermatology and Cutaneous Surgery at the University of Miami Health System launches newly named Skin of Color Division led by a three-physician team – all women of color. Only a handful of dermatology programs across the country have so many physicians specializing in skin of color care.
The study will aim to understand whether systemic medications and biologics, such as dupilumab—a monoclonal antibody that binds to an inflammatory molecule, IL-4 receptor alfa, and inhibits the inflammatory response that leads to rashes and itching from atopic dermatitis/eczema—may have a positive or negative impact on COVID-19 responses in patients who have the disease.
Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy. PRMT5 inhibitors are currently in clinical trials in oncology, and this research provides a strong rationale for evaluating the drugs in tumors that are not responsive to immune checkpoint therapy. The study was published in Science Translational Medicine.
The American Academy of Dermatology (AAD) has named board-certified dermatologist Kari Lyn Martin, MD, FAAD, a Patient Care Hero for using telemedicine to diagnose and remove a patient’s melanoma the same day.
July is UV Safety Month, the perfect time to raise awareness about the risk of developing sun-related skin cancer. Rutgers Cancer Institute expert shares tips about how to reduce skin cancer risk during the summer months when UV rays are the strongest.
Janice M. Mehnert, MD, a nationally recognized expert in early phase therapeutics and the treatment of skin malignancies, has been appointed associate director for clinical research at NYU Langone Health’s Perlmutter Cancer Center. She assumes her post July 1, 2020.
Skin cancer is the most common cancer in the U.S., and nearly 20 Americans die from melanoma, the deadliest form of skin cancer, every day. As more Americans prepare to head outdoors for the 4th of July holiday, dermatologists from the American Academy of Dermatology have an important reminder: dress to protect yourself from the sun. In addition to seeking shade and applying sunscreen, wearing protective clothing goes a long way in protecting you from the sun’s harmful UV rays, which can increase your risk of skin cancer. However, not all clothing is created equal when it comes to sun protection, say dermatologists. Some garments provide better UV protection than others.
A new study from Binghamton University, State University of New York may help to peel back the layers of unhealthy skin — at least metaphorically speaking — and get closer to a cure.
With Father’s Day approaching, dermatologists are giving parents two thumbs up for keeping sun protection top of mind for their families. According to a new survey from the American Academy of Dermatology, 74% of parents today say they worry about sun protection more with their children than their parents did with them, and 90% of parents believe it’s important to teach their children healthy habits now so they will keep them when they are adults.
Approximately 7.5 million people in the U.S. have psoriasis, a chronic inflammatory disease that mostly affects the skin and joints but could also affect the nails. According to dermatologists from the American Academy of Dermatology, most people who have plaque psoriasis — the most common form of psoriasis — also develop nail psoriasis at some point. This is why dermatologists say it’s important for psoriasis patients to check their nails — both their fingernails and toenails — for signs of nail psoriasis, which can include nail dents, lifting, discoloration, thickening and crumbling. However, it’s also possible for patients to experience nail psoriasis without having psoriasis on other parts of their body.
A team led by Case Western Reserve University School of Medicine researchers has made two major discoveries involving psoriasis, a chronic and debilitating skin disease with no known cure.
For a while now, some plastic surgeons have been using stem cells to treat aging, sun-damaged skin. But while they’ve been getting good results, it’s been unclear exactly how these treatments – using adult stem cells harvested from the patient’s own body – work to rejuvenate “photoaged” facial skin.
Upon exposure to human skin, ultraviolet light from the sun almost instantly generates two types of "lesions" that damage DNA. Scientists at UW Medicine in Seattle determined which of these lesions is responsible for activating a process that may increase cancerous mutations in cells.
Skin cancer and skin infection are significantly more likely in solid organ transplant patients compared to patients with normal immune system function. Almost 40,000 organ transplants were performed in the United States in 2019, a 9% increase over 2018.
Memorial Day — long considered the unofficial start of summer in the U.S. — is quickly approaching, and dermatologists from the American Academy of Dermatology are urging Americans to practice safe sun as they head outdoors, especially as shelter-in-place measures related to COVID-19 begin to lift. Skin cancer is the most common cancer in the U.S., affecting one in five Americans in their lifetime, yet new data from the AAD shows that many Americans aren’t protecting themselves from the sun’s harmful ultraviolet (UV) rays.
A recent survey from the George Washington University suggests that patients do not take social media into consideration when looking for a dermatologist and recommend that practitioners should use social media as a tool in engaging and educating patients.
A recent survey from the GW Cancer Center found that enrollment in a supportive oncodermatology program is associated with a significantly improved quality of life score. The results are published in the Journal of Drugs in Dermatology.
Black patients with one of the deadliest forms of skin cancer are likely to experience a longer delay from diagnosis to surgery than non-Hispanic white (NHW) patients, according to a new study published in the Journal of the American Academy of Dermatology.
As more Americans head outdoors for warmer weather and fresh air amid “shelter-in-place” measures, dermatologists from the American Academy of Dermatology have an important reminder: practice safe sun. Skin cancer is one of the most preventable types of cancer, but new data from the AAD shows that many Americans aren’t taking the necessary steps to protect themselves.