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Released: 22-Jan-2018 12:05 PM EST
Tissue Engineering to Improve the Most Common Orthopaedic Surgery
Perelman School of Medicine at the University of Pennsylvania

Researchers at Penn are working to uncover ways to encourage the cells in and around the meniscus to repair themselves, hopefully leading to less invasive procedures.

Released: 22-Jan-2018 11:05 AM EST
Let’s Talk About End-of-Life Care
National Comprehensive Cancer Network® (NCCN®)

A new study in JNCCN finds majority of people with cancer would like their physicians to ask them where they would prefer to receive end-of-life care.

Released: 22-Jan-2018 10:05 AM EST
Vandana Gopikumar, PhD, to Receive 2018 Penn Nursing Renfield Foundation Award for Global Women’s Health
University of Pennsylvania School of Nursing

Vandana Gopikumar, PhD, Co-Founder of The Banyan and The Banyan Academy of Leadership in Mental Health will receive the 2018 Penn Nursing Renfield Foundation Award for Global Women’s Health for her work in helping women with mental health problems in India. She co-founded both organizations with Vaishnavi Jayakumar. Gopikumar will receive the award – which comes with a $100,000 cash prize – during an event at the University of Pennsylvania on March 21, 2018.

Released: 18-Jan-2018 4:20 PM EST
Patients Who Live Alone Can Safely Be Sent Home After Joint Replacement
Wolters Kluwer Health: Lippincott

Most patients who live alone can be safely discharged home from the hospital to recover after hip or knee replacement surgery, suggests a study in the January 17, 2018 issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.

Released: 18-Jan-2018 11:05 AM EST
The Wistar Institute Awarded More Than $1.4 Million to Create a Malaria Vaccine Through Synthetic DNA-Based Technology
Wistar Institute

Wistar is pleased to announce it has been awarded a $1,494,972 grant by the Bill & Melinda Gates Foundation to advance a DNA-based vaccine candidate for protection against malarial infection utilizing a synthetic DNA platform created in the lab of David B. Weiner, Ph.D., executive vice president, director of the Vaccine & Immunotherapy Center at The Wistar Institute and the W.W. Smith Charitable Trust Professor in Cancer Research.

   
Released: 18-Jan-2018 10:05 AM EST
Americans Are Getting More ZZZZs
Perelman School of Medicine at the University of Pennsylvania

Decline in reading and watching TV before bed and increasing opportunities to perform tasks online and from home could be why, Penn study finds

Released: 18-Jan-2018 8:05 AM EST
Novel Method of Isolating Infecting Organisms After Joint Replacement
Thomas Jefferson University

Next-generation Genomic Sequencing could help identify infecting organisms and guide treatment for patients with joint-replacement infection

16-Jan-2018 3:05 PM EST
Default Setting in Electronic Medical Records “Nudged” Emergency Department Physicians to Limit Opioid Prescriptions to 10 Tablets
Perelman School of Medicine at the University of Pennsylvania

For patients who have never been prescribed opioids, larger numbers of tablets given with the initial prescription is associated with long-term use and more tablets leftover that could be diverted for misuse or abuse. Implementing a default option for a lower quantity of tablets in the electronic medical records (EMR) discharge orders may help combat the issue by “nudging” physicians to prescribe smaller quantities consistent with prescribing guidelines Penn Medicine researchers show in a new study published this week in the Journal of General Internal Medicine.

Released: 17-Jan-2018 4:05 PM EST
Fluctuations of Sex Steroid Hormone Could be Culprit in Age-Related Macular Degeneration
Sbarro Health Research Organization (SHRO)

Gender-based differences may influence several ocular conditions, suggesting that fluctuations in sex steroid homeostasis may have direct effects on eye physiology and the pathogenesis of conditions like Age-Related Macular Degeneration (AMD).

Released: 17-Jan-2018 12:05 PM EST
When it Comes to Science, it’s a Small, Small World
Wistar Institute

Immortalized human skin cells that look like a psychedelic otherworldly galaxy and a living algae colony releasing its daughter colonies that could be mistaken for Pacman gobbling up ghosts are just two of the winning images from the 2017 Nikon Small World competition of photomicrography–photography taken through microscopes–that arrive at The Wistar Institute with an opening reception on Jan. 19.

 
Released: 16-Jan-2018 10:40 AM EST
Evidence Supports 'Weekend Effect' for Mortality after Surgery
Wolters Kluwer Health: Lippincott

As for other types of medical care, surgery appears to be prone to a significant "weekend effect"— with higher odds of death when surgery is performed during or one or two days before the weekend, suggests a report in the February issue of Medical Care, published by Wolters Kluwer.

Released: 16-Jan-2018 10:30 AM EST
Elevating Patient Care: Penn Medicine Orthopaedics and Princeton Orthopedic Associates Forge Strategic Partnership
Perelman School of Medicine at the University of Pennsylvania

Penn Orthopaedics and Princeton Orthopedic Associates have announced a new strategic alliance in an effort to enhance and continue to improve orthopaedic care to patients in New Jersey and Pennsylvania. As part of the Penn Medicine Orthopaedic Specialty Network, physicians and surgeons at each entity will work collaboratively across state lines to expand patients’ access to highly specialized orthopaedic care, while improving care team communication and processes, and collecting data to help physicians advance clinical research and care.

Released: 16-Jan-2018 9:05 AM EST
Temple University Hospital Ranked #1 in the Nation for Lung Transplant Volume in 2017
Temple University

Temple University Hospital (TUH) performed 131 lung transplants in calendar year 2017, making it the number 1 volume program in the nation according to data just released by the United Network for Organ Sharing (UNOS).

Released: 16-Jan-2018 12:05 AM EST
Penn Researchers Identify New Treatment Target for Melanoma
Perelman School of Medicine at the University of Pennsylvania

Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a new therapeutic target for the treatment of melanoma. For decades, research has associated female sex and a history of previous pregnancy with better outcomes after a melanoma diagnosis. Now, a research team from Perelman School of Medicine at the University of Pennsylvania says it may have determined the reason for the melanoma-protective effect.

Released: 15-Jan-2018 11:05 AM EST
Insurance Company Requirements Place Heavy Administrative Burden on Physicians Seeking to Prescribe New Cholesterol-Lowering Drugs
Perelman School of Medicine at the University of Pennsylvania

A rare glimpse into the prior authorization requirements implemented by public and private insurance providers across the country has found substantial administrative burden for a new class of medications for patients with high cholesterol that places them at high risk for heart attack or stroke. So-called proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are self-injected medications approved for individuals with a genetic condition called familial hypercholesterolemia (FH) and those with atherosclerotic cardiovascular disease (ASCVD) who have high cholesterol despite receiving traditional statin medications and other treatments. Results of the study are published in Circulation: Cardiovascular Quality and Outcomes.

Released: 12-Jan-2018 3:50 PM EST
Can Early Symptoms Predict Bipolar Disorder? Evidence Shows Differing Patterns of Risk Factors
Wolters Kluwer Health: Lippincott

Two patterns of antecedent or "prodromal" psychiatric symptoms may help to identify young persons at increased risk of developing bipolar disorder (BD), according to a new analysis in the Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.

Released: 12-Jan-2018 1:05 PM EST
Past Exposures Shape Immune Response in Pediatric Acute Respiratory Infections
Perelman School of Medicine at the University of Pennsylvania

By analyzing immune cells of children who came to the emergency department with flu symptoms, researchers found that the suite of genes these early-response cells expressed was shaped by factors such as age and previous exposures to viruses. Better understanding how early infections influence long-term immune response has implications for the diagnosis and treatment of young patients who suffer from acute respiratory tract infections.

10-Jan-2018 12:00 PM EST
Nurse Staffing Levels Linked to Patient Satisfaction
University of Pennsylvania School of Nursing

Satisfaction with care in hospitals declines when patients believe there are not enough nurses on wards, according to a new study based on the NHS Inpatient Survey published in the BMJ Open.

Released: 10-Jan-2018 12:05 PM EST
Can Vitamins and Dietary Supplements Benefit Patients with Mitochondrial Disease?
Children's Hospital of Philadelphia

Defects in mitochondria, the tiny structures that power our cells by functioning as biological batteries, cause an array of complex, often life-threatening disorders that can affect any and all organs and systems. In the absence of validated, effective drug treatments, patients with mitochondrial disease often take a variety of vitamins and supplements, substances that are largely unstandardized, unregulated, and unproven. A group of medical experts recommend performing systematic scientific studies to test precise nutritional interventions for patients.

Released: 10-Jan-2018 11:25 AM EST
JOT Releases Orthopaedic Residency Program Rankings by Research Output
Wolters Kluwer Health: Lippincott

What's the best way to rate the quality and quantity of research produced by orthopaedic surgery residency programs? A new "research impact ranking" provides a more objective approach to assessing and comparing research productivity at US orthopaedic departments, according to a study in the November Journal of Orthopaedic Trauma (JOT), published by Wolters Kluwer.

Released: 9-Jan-2018 10:25 AM EST
New Skin Barrier Product Reduces Costs for Ostomy Care
Wolters Kluwer Health: Lippincott

Ostomy patients using a new type of skin barrier product—infused with ceramides that play an essential role in the normal barrier function of the skin—experience lower costs of care, according to a randomized trial published in the Journal of Wound, Ostomy and Continence Nursing, the official journal of the Wound, Ostomy and Continence Nurses (WOCN®) Society. The journal is published by Wolters Kluwer.

Released: 9-Jan-2018 8:15 AM EST
Fox School of Business Online MBA Earns No. 1 National Ranking From U.S. News for Fourth Straight Year
Temple University

The Fox School of Business at Temple University in Philadelphia remains a national leader in the delivery of online business programs.

Released: 8-Jan-2018 10:05 AM EST
Managing Obesity in the Workplace − New Guidance from ACOEM
Wolters Kluwer Health: Lippincott

Effective prevention and treatment steps—including coverage for bariatric surgery, when indicated—can help employers to control the health and economic impact of obesity in the workplace, according to an ACOEM Guidance Statement, published in the January Journal of Occupational and Environmental Medicine.

Released: 5-Jan-2018 2:05 PM EST
Penn Study on Super-Silenced DNA Hints at New Ways to Reprogram Cells
Perelman School of Medicine at the University of Pennsylvania

Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity to use in regenerative medicine studies and one day in the clinic.

Released: 4-Jan-2018 2:25 PM EST
Lymphedema after Cancer Treatment – Special Issue of Rehabilitation Oncology Presents Research Update
Wolters Kluwer Health: Lippincott

Individuals who have been treated for cancer are at risk for a complication called lymphedema: swelling in the body region where lymph nodes were removed, causing pain and limited function. New research and insights on the management of cancer-related lymphedema are presented in the January special issue of Rehabilitation Oncology, official journal of the Oncology Section of the American Physical Therapy Association. The journal is published by Wolters Kluwer.

Released: 3-Jan-2018 1:45 PM EST
Temple University Professors Available to Discuss Sexual Harassment, Discrimination, Workplace Conditions
Temple University

Two professors from Temple's Fox School of Business can address employment discrimination, workplace culture and conflict, sexual harassment, and more

   
Released: 3-Jan-2018 10:05 AM EST
Penn Medicine Chief Scientific Officer Receives Outstanding Investigator Award from the National Heart, Lung, and Blood Institute
Perelman School of Medicine at the University of Pennsylvania

Jonathan A. Epstein, MD, executive vice dean and chief scientific officer of Penn Medicine, has received a National Heart, Lung, and Blood Institute (NHLBI) Outstanding Investigator Award. The highly competitive award provides long-term support to “an experienced investigator with an outstanding record of research productivity.” In issuing the award, the NHLBI, which is part of the National Institutes of Health, described Epstein as “an outstanding, pioneering investigator” and “a gold standard role model for physician-scientists in the field.”

Released: 2-Jan-2018 1:40 PM EST
Educational Video May Increase Public Willingness to Become Face Transplant Donors
Wolters Kluwer Health: Lippincott

After watching a brief educational video, members of the public are more likely to say they would be willing to donate a facial transplant to a severely disfigured patient, reports a study in the January issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

Released: 2-Jan-2018 11:15 AM EST
Migraine Surgery Produces 'Dramatic Improvements' in Functioning, Study Finds
Wolters Kluwer Health: Lippincott

In addition to reducing headache frequency and severity, surgical treatment for migraine leads to significant improvements in everyday functioning and coping ability, according to a study in the January issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

Released: 2-Jan-2018 9:00 AM EST
Detecting Pompe Disease with More Accuracy Key to Urgent Intervention
Sbarro Health Research Organization (SHRO)

Researchers identified a new, more sensitive screening test to recognize Pompe disease, a metabolic disorder affecting cellular processing of glycogen in numerous tissues of the body.

Released: 28-Dec-2017 11:05 AM EST
Carfilzomib Can Lead to Cardiovascular Toxicity in Multiple Myeloma Patients
Perelman School of Medicine at the University of Pennsylvania

The proteasome inhibitor carfilzomib has taken on an increasing role in the treatment of multiple myeloma, but new research from the Abramson Cancer Center of the University of Pennsylvania shows the therapy comes with the risk of cardiovascular problems in a higher than expected percentage of patients.

Released: 27-Dec-2017 4:10 PM EST
American Journal of Nursing Announces 2017 Book of the Year Awards
Wolters Kluwer Health: Lippincott

Wolters Kluwer Health and the American Journal of Nursing (AJN) are pleased to announce the 2017 winners of its annual AJN Book of the Year Awards honoring exceptional texts for advancing healthcare quality. The list of winners appears in the January 2018 issue of AJN, the “leading voice of nursing since 1900.”

Released: 27-Dec-2017 3:15 PM EST
Local Economic Factors Affect Opioid Prescribing to Disabled Medicare Beneficiaries
Wolters Kluwer Health: Lippincott

For non-elderly Americans on disability, local prescribing of opioid pain medications is significantly related to county-level economic factors like unemployment and income level, reports a study in the January issue of Medical Care, published by Wolters Kluwer.

Released: 27-Dec-2017 9:10 AM EST
Insurance Industry Research Reveals More Women in Leadership Roles
Saint Joseph's University

New insurance industry demographic research from Saint Joseph’s University in Philadelphia reveals significant improvement in gender inclusion in senior leadership positions. The study builds on four years of work by Mike Angelina, executive director of the Maguire Academy of Insurance and Risk Management

Released: 26-Dec-2017 11:45 AM EST
New Laws Increase Access to Healthcare Delivery for Advanced Practice Registered Nurses
Wolters Kluwer Health: Lippincott

As 2017 comes to a close, many states have enacted laws and regulations expanding access to healthcare provided by advanced practice registered nurses (APRNs), according to the 30th Annual Legislative Update in the January issue of The Nurse Practitioner, published by Wolters Kluwer.

Released: 21-Dec-2017 2:30 PM EST
Xylella: A Conscience, Not a Science Problem
Sbarro Health Research Organization (SHRO)

The Sbarro Health Research Organization congratulates the Italian researchers who were able to prove a direct causal link between the infection by Xylella fastidiosa and the death of olive trees in southern Italy.

20-Dec-2017 9:00 AM EST
High Out-of-Pocket Costs May Place Oral Cancer Medications Out of Reach
Perelman School of Medicine at the University of Pennsylvania

Sticker shock may be leading many insured Americans with cancer to forego treatment with a wide range of oral cancer drugs, suggests a study published online this week in the Journal of Clinical Oncology. Led by researchers at the Perelman School of Medicine at the University of Pennsylvania, the findings point to high out-of-pocket costs as a barrier to potentially life-saving or life-prolonging treatments. As breakthroughs in cancer care continue, the study raises questions about whether patients will able to take advantage of new treatment options.

19-Dec-2017 11:00 AM EST
Novel Combination Therapy Shown to Be Effective in Ovarian Cancer
Wistar Institute

Wistar researchers have found that combining PARP inhibitors, recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers without BRCA1 and BRCA2 gene mutations.

   
Released: 19-Dec-2017 11:05 AM EST
FDA Approves Gene Therapy for Inherited Blindness Developed by the University of Pennsylvania and Children’s Hospital of Philadelphia
Perelman School of Medicine at the University of Pennsylvania

In a historic move, the U.S. Food and Drug Administration (FDA) today approved a gene therapy initially developed by researchers at the University of Pennsylvania and Children’s Hospital of Philadelphia (CHOP) for the treatment of a rare, inherited form of retinal blindness. The decision marks the nation’s first gene therapy approved for the treatment of a genetic disease, and the first in which a new, corrective gene is injected directly into a patient.

Released: 19-Dec-2017 10:25 AM EST
Study Finds Growing Socioeconomic and Racial Disparities in Management of Brain Metastases
National Comprehensive Cancer Network® (NCCN®)

A new study in the Journal of the National Comprehensive Cancer Network highlights the need to improve access to stereotactic radiosurgery following radiotherapy to treat brain metastases for minority and lower-income populations.

Released: 18-Dec-2017 4:05 PM EST
Sharing Examples of Caring this Season
Perelman School of Medicine at the University of Pennsylvania

In honor of the season of giving, Penn Medicine debuts four new short videos of Penn Medicine CAREs-funded initiatives making a difference all year long.



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