Feature Channels: Drugs and Drug Abuse

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1-Apr-2019 9:00 AM EDT
Combining Opioids and Marijuana May Be Advantageous for Pain Sufferers
Federation of American Societies for Experimental Biology (FASEB)

New findings suggest using opioids and marijuana together could offer a safe way to cut opioid dosage among patients suffering from pain and thereby reduce their risk of becoming addicted to opioids.

Released: 8-Apr-2019 7:00 AM EDT
Opioid Addiction Meets Pain Management, A Frank Discussion Among Practitioners
American Association of Endodontists (AAE)

CHICAGO – This month, dentists with advanced training in root canals known as endodontists, will get together to discuss the latest and best practices for responsibly managing a patient’s pain and the steps that can be taken to minimize the risk for prescription drug abuse.

1-Apr-2019 9:00 AM EDT
Experimental Drug Shows Promise for Opioid Withdrawal Symptoms
Federation of American Societies for Experimental Biology (FASEB)

New findings suggest rapastinel could be useful to help manage withdrawal during the critical first days after someone has entered treatment and is trying to abstain from opioid use, according to researchers.

1-Apr-2019 9:00 AM EDT
Scientists Find New Therapy Target for Drug-Induced Liver Failure
Federation of American Societies for Experimental Biology (FASEB)

Findings from a new mouse study suggest that treatments that increase levels of the protein thrombospondin-1 could help the liver recover from an overdose of acetaminophen.

Released: 5-Apr-2019 11:05 AM EDT
Emergency department program aims at reducing opioid use disorder
University of Alabama at Birmingham

UAB launches an emergency room-based medication assisted treatment program, which includes providing peer navigators and certifying more physicians to prescribe Suboxone in an effort to corral the opioid crisis.

Released: 4-Apr-2019 2:05 PM EDT
ASA Supports Key Elements of HHS Pain Task Force Recommendations
American Society of Anesthesiologists (ASA)

In comments submitted to the federal government, the American Society of Anesthesiologists (ASA) formally supported the recommendations of the U.S. Department of Health and Human Services (HHS) Pain Management Best Practices Interagency Task Force.

Released: 4-Apr-2019 12:05 PM EDT
Could a Vaccine Prevent Opioid Addiction?
Northern Arizona University

A research team that includes Northern Arizona University chemistry professor Naomi Lee received an NIH grant to develop a vaccine that can blunt the effects of drugs by triggering the patient's immune system.

   
Released: 4-Apr-2019 9:00 AM EDT
Psychedelic Drug MDMA May Reawaken ‘Critical Period’ in Brain to Help Treat PTSD
Johns Hopkins Medicine

Johns Hopkins neuroscientists have found that the psychedelic drug MDMA reopens a kind of window, called a “critical period,” when the brain is sensitive to learning the reward value of social behaviors. The findings, reported April 3 in Nature, may explain why MDMA may be helpful in treating people with post-traumatic stress disorder (PTSD).

Released: 1-Apr-2019 9:00 AM EDT
Experimental Biology Highlights – Environment and Public Health
Federation of American Societies for Experimental Biology (FASEB)

Embargoed press materials are now available for the Experimental Biology (EB) 2019 meeting, to be held in Orlando April 6–9. EB is the annual meeting of five scientific societies bringing together more than 12,000 scientists and 25 guest societies in one interdisciplinary community.

19-Mar-2019 8:00 AM EDT
Next-Generation Single-Dose Antidotes for Opioid Overdoses
American Chemical Society (ACS)

Fentanyl’s powerful effects are long-lasting, and even tiny amounts of the drug can lead to an overdose. Antidotes, do not last long enough in the body to fully counter the drug, requiring repeated injections. Now, scientists report that they are developing single-dose, longer-lasting opioid antidotes.

   
25-Mar-2019 2:05 PM EDT
To Keep Leftover Opioids Out of Harm’s Way, Give Surgery Patients Special Disposal Bags, Study Shows
Michigan Medicine - University of Michigan

Many surgery patients head home from the hospital with opioid pain medicine prescriptions, and most will have pills left over after they finish recovering from their procedure. Now, a new study suggests patients should also leave the hospital with something to help them safely get rid of those leftovers – and keep pills from being misused or polluting the environment.

26-Mar-2019 4:00 PM EDT
Cannabis During Pregnancy Bumps Psychosis Risk in Offspring
Washington University in St. Louis

Pregnant women who use cannabis may slightly increase the risk their unborn child will develop psychosis later in life, suggests new research from Washington University in St. Louis.

20-Mar-2019 9:00 AM EDT
Recovery from sperm suppression due to performance-enhancing drug abuse is slow
Endocrine Society

Decreased sperm and testosterone production caused by abuse of performing-enhancing hormones may be fully reversible once men stop taking the drugs, but full recovery can take at least nine to 18 months, according to research to be presented Sunday, March 24 at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La.

Released: 25-Mar-2019 9:00 AM EDT
Hearing Loss Before 50 May Mean Higher Risk of Drug and Alcohol Issues
Michigan Medicine - University of Michigan

People under age 50 with hearing loss misuse prescription opioids at twice the rate of their hearing peers, and are also more likely to misuse alcohol and other drugs, a new national study finds. Health care providers may need to take special care when treating pain and mental health conditions in deaf and hard-of-hearing young adults.

20-Mar-2019 9:00 AM EDT
Another possible consequence of the opioid epidemic: hormone deficiencies
Endocrine Society

Many people who use opioid medications long term do not produce enough testosterone or another important hormone, cortisol, according to a new study. Results of what the researchers called “the most up-to-date and most comprehensive clinical review of endocrine effects of long-term opioid use” are being presented Sunday at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La.

Released: 21-Mar-2019 12:00 PM EDT
Naltrexone Implant Helps HIV Patients with Opioid Dependence Adhere to Medications, Prevent Relapse
Perelman School of Medicine at the University of Pennsylvania

A new study, published this month in Lancet HIV by Penn Medicine researchers, shows that a naltrexone implant placed under the skin was more effective at helping HIV-positive patients with an opioid addiction reduce relapse and have better HIV-related outcomes compared to the oral drug.

Released: 21-Mar-2019 9:00 AM EDT
Nurse Anesthetists Association Joins Voices for Non-Opioid Choices Coalition
American Association of Nurse Anesthesiology

The American Association of Nurse Anesthetists (AANA) joins Voices for Non-Opioid Choices, a rising non-partisan coalition group dedicated to to curbing the U.S. opioids crisis by increasing patient access to non-opioid therapies and acute pain management.

Released: 18-Mar-2019 12:00 PM EDT
Fast-Acting Psychedelic Can Improve Depression, Anxiety
Johns Hopkins Medicine

Johns Hopkins researchers have discovered that use of the synthetic psychedelic 5-methocy-N,-N-dimethyltryptamine (5-MeO-DMT) appears to be associated with unintended improvements in self-reported depression and anxiety when given in a ceremonial group setting. 5-MeO-DMT is a psychedelic that is found in the venom of Bufo Alvarius toads, in a variety of plants species, and can be produced synthetically.

Released: 14-Mar-2019 2:35 PM EDT
Researchers Present New Discoveries in Maternal-Fetal Medicine at National Conference
University of Texas Health Science Center at Houston

New insights into opioid alternatives to treat postpartum pain and medication to delay preterm labor, as well as breakthroughs in spina bifida surgery, were among the topics of research presented at the Society for Maternal-Fetal Medicine’s (SMFM) 39th Annual Pregnancy Meeting by faculty, students, and staff from UTHealth.

11-Mar-2019 1:00 PM EDT
Dramatic Shifts in First-time Opioid Prescriptions Bring Hope, Concern
Harvard Medical School

Analysis shows the monthly rate of first-time opioid prescriptions dropped by more than half between 2012 and 2017. Though some physicians wrote no new prescriptions at all, others continued to prescribe dosages and durations that put patients at risk for misuse, overdose and death. Findings underscore importance of nuanced, individualized prescribing over all-or-nothing approach.

Released: 12-Mar-2019 2:05 PM EDT
Research Points to Ways to Reduce Opioid Use Following Common Orthopedic Surgeries
NYU Langone Health

New research presented American Academy of Orthopaedic Surgeons (AAOS) 2019 reports on the results of a major undertaking by the Department of Orthopedic Surgery at NYU Langone Health to curb opioid prescriptions and usage rates following common orthopedic procedures.

Released: 12-Mar-2019 10:05 AM EDT
HSS Orthopedic Surgeons Address Opioid Epidemic Head On
Hospital for Special Surgery

Orthopedic surgeons at Hospital for Special Surgery have developed a pain management pathway designed to reduce the use of opioid medication after joint procedures.

Released: 4-Mar-2019 12:05 PM EST
Young People at Risk of Addiction Have Differences in Key Brain Region
University of Cambridge

Young adults at risk of developing problems with addiction show key differences in an important region of the brain, according to an international team led by researchers at the University of Cambridge.

Released: 27-Feb-2019 10:05 PM EST
Multi-agency Partnership Launches $1.55M Challenge for New Solutions to Detect Opioids
Homeland Security's Science And Technology Directorate

Today, the Opioid Detection Challenge, a $1.55 million USD global prize competition, was launched by DHS S&T, in collaboration with U.S. Customs and Border Protection (CBP), the Office of National Drug Control Policy (ONDCP), and the U.S. Postal Inspection Service (USPIS).

25-Feb-2019 2:05 PM EST
Study Identifies Predictors of Psychiatric Events During Drug-Assisted Smoking Cessation
UC San Diego Health

Researchers at UC San Diego School of Medicine have identified a clear group of characteristics that predict heightened risk for experiencing increased anxiety or worsening of mood that interferes with daily activities when using a smoking cessation drug. Results are published in the February 27 online edition of the Journal of General Internal Medicine.

Released: 27-Feb-2019 2:45 PM EST
Study reveals structure of 2nd human cannabinoid receptor
Moscow Institute of Physics and Technology (MIPT)

There are two cannabinoid receptors (CB1 and CB2) in the human body that can be targeted to alleviate certain pathological conditions, including chronic pain. While the CB1 receptors are mostly found in the nervous system and are responsible for psychoactive effects, the CB2 receptors are predominantly present in the immune system. Studies indicate that CB2 is a promising target for immunotherapy, as well as treating inflammatory and neuropathic pain, and neurodegenerative diseases. It has also been shown that molecules blocking CB2 can reduce tumor growth.

Released: 27-Feb-2019 11:05 AM EST
THC Found More Important for Therapeutic Effects in Cannabis Than Originally Thought
University of New Mexico

Researchers at the University of New Mexico (UNM) recently solved a major gap in scientific literature by using mobile software technology to measure the real-time effects of actual cannabis-based products used by millions of people every day.

Released: 27-Feb-2019 9:55 AM EST
APQ Calls on Attorney General to Break Logjam Surrounding Applications From Cannabis Growers to Enable Needed Research
American Psychological Association (APA)

The American Psychological Association has asked the U.S. attorney general to act immediately to evaluate the more than two dozen cannabis grower applications that have been languishing for more than two years at the Department of Justice, noting that the scientific community is eager to advance the research on both the harmful and therapeutic effects of marijuana and its derivatives.

20-Feb-2019 3:55 PM EST
Geographic Distribution of Opioid-Related Deaths
JAMA - Journal of the American Medical Association

Assessment of Changes in the Geographical Distribution of Opioid-Related Mortality Across the United States by Opioid Type, 1999-2016

18-Feb-2019 6:00 AM EST
Virtual Reality Intervention Shows Promise for Back Pain Patients Who Are Afraid to be Active
Association of Academic Physiatrists (AAP)

A new virtual reality physical activity intervention may be effective for people with chronic low back pain who avoid activity because of fear, helping them to become physically active once again.

18-Feb-2019 6:00 AM EST
Smokers Are At High Risk for Low Back Pain, Hospitalization and Opioid Use
Association of Academic Physiatrists (AAP)

Smokers are at high risk for low back pain, and also have higher rates of healthcare utilization and opioid use, and physicians should ask these patients about other comorbidities that may make their pain treatment more difficult.

18-Feb-2019 6:00 AM EST
Interdisciplinary Pain Management Approach May Reduce Opioid and Benzodiazepine Use in Chronic Pain Patients
Association of Academic Physiatrists (AAP)

A four-week interdisciplinary pain management program for worker’s compensation patients with chronic pain significantly reduced their opioid and benzodiazepine use.

Released: 20-Feb-2019 11:05 AM EST
Program Gives UC San Diego Health New Resources to Combat Opioid Epidemic
UC San Diego Health

UC San Diego Health is among 31 health facilities selected from across the state to participate in the California Bridge Program, an accelerated, 18-month training program for health care providers to enhance access to around-the-clock treatment for patients with opioid use disorder.

14-Feb-2019 4:30 PM EST
Study Finds Inadequate FDA Oversight of Prescribing of Fentanyl Products
Johns Hopkins Bloomberg School of Public Health

A study led by researchers at the Johns Hopkins Bloomberg School of Public Health suggests that the Food and Drug Administration (FDA) and manufacturers did not take action when evidence emerged that potentially lethal fentanyl products were being inappropriately prescribed to patients.

Released: 14-Feb-2019 3:05 PM EST
Immune Profiling: A New Opportunity for Drug Development
Perelman School of Medicine at the University of Pennsylvania

Collectively, assessing a snapshot of a person’s unique state of immune health is called immune profiling, which can entail identifying immune-cell-associated genes and proteins, as well as the cell types themselves.

Released: 12-Feb-2019 11:05 AM EST
Time for a talk about vaping?
UT Southwestern Medical Center

With new findings that show an unprecedented jump in nicotine-containing electronic cigarette usage among teens, many parents wonder how best to approach the topic.

Released: 11-Feb-2019 3:00 PM EST
Researchers Identify Brain Protein Crucial to Recovery from Stroke
Health Sciences at the University of Pittsburgh

Researchers at the University of Pittsburgh School of Medicine have identified a brain protein at the root of how the brain recovers from stroke. The finding offers a promising avenue for developing therapies that could work even when given beyond the first few hours after a stroke.

Released: 7-Feb-2019 1:05 PM EST
Surgeons investigate modified pain management strategies to reduce opioid use in trauma patients
University of Texas Health Science Center at Houston

A team of surgeons is working to identify the most effective strategy to treat acute pain after injury while minimizing the amount of opioids prescribed to trauma patients, building on a previous project that decreased use of the highly addictive class of drugs by 40 percent.

6-Feb-2019 7:05 AM EST
Fewer Deaths Seen Among Young Adults Who Got Extra Adult Support as Suicidal Teens
Michigan Medicine - University of Michigan

Building a circle of trusted adults around a suicidal teen, to support them during vulnerable times, may have long-term effects that reduce their risk of dying young, a new study suggests. About 12 years after the teens were hospitalized for suicidal behaviors, far more of the young people who got standard care had died, compared with young adults in the group that had received the extra adult support.

Released: 5-Feb-2019 3:05 PM EST
HEROES Program Awarded More Than $2 Million to Continue Opioid Intervention Outreach in Houston
University of Texas Health Science Center at Houston

The Houston Emergency Response Opioid Engagement System (HEROES) was recently awarded two grants that will help fund the opioid intervention program through the end of 2020. James Langabeer, PhD, MBA, a professor at The University of Texas Health Science Center at Houston (UTHealth), created the program to provide comprehensive treatment for opioid abusers, gain a more thorough understanding of the epidemic in Houston, and work toward getting the highly addictive drugs off the streets.

31-Jan-2019 5:05 PM EST
Training the Prescriber: An Institutional Effort to Reduce the Amount of Opioids Prescribed Following Lumbar Surgery
Journal of Neurosurgery

The authors assess the effect of a mandatory educational program and new institutional prescriber guidelines on the behavior of physicians who prescribe opioid medications following lumbar surgery

31-Jan-2019 2:05 PM EST
What Drives Patients to Use Medical Marijuana: Mostly Chronic Pain
Michigan Medicine - University of Michigan

New U-M study seeks to understand whether people are using cannabis for evidence-based reasons.

Released: 4-Feb-2019 12:30 PM EST
Saint Joseph’s University Bioethicist Calls for Safe Injection Sites; Proposes Customized Model for Philadelphia
Saint Joseph's University

University’s nationally-recognized Institute of Clinical Bioethics collaborates with local institutions on newly published paper proposing a model for safe injection sites designed to prevent the deaths of thousands of Philadelphians vulnerable to an opioid overdose.

Released: 4-Feb-2019 10:10 AM EST
Fatal Opioid-Related Car Crashes in Maryland Hold Steady Over Decade
Johns Hopkins Bloomberg School of Public Health

A new approach to defining opioid-related auto fatalities provides insight into the nature and distribution of opioid-involved deaths in the state of Maryland, say the authors of a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

Released: 4-Feb-2019 3:05 AM EST
Rutgers Study Finds Rise in Overdoses from Opioids in Diarrhea Drug
Rutgers University-New Brunswick

Rutgers Study Finds Rise in Overdoses from Opioids in Diarrhea Drug



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