Patients whose brains appear older on scans than their chronological age showed less improvement on sertraline, a first-line drug treatment for major depressive disorder (MDD), researchers from UT Southwestern Medical Center reported.
The prevalence of three different types of disabilities among Black and White Americans aged 65 and older plummeted in the decade between 2008 and 2017 according to a new nationally representative study published online in the International Journal of Ageing and Human Development.
In Journal of Applied Physics, Markus Buehler combines attention neural networks with graph neural networks to better understand and design proteins. The approach couples the strengths of geometric deep learning with those of language models to predict existing protein properties and envision new proteins that nature has not yet devised. Buehler’s model turns numbers, descriptions, tasks, and other elements into symbols for his neural networks to use.
How much time elapses between a blow to the head and the start of damage associated with Alzheimer’s disease?
Brent Forester, the Dr. Frances S. Arkin Chair of Psychiatry at Tufts University School of Medicine and psychiatrist-in-chief and chair of the Department of Psychiatry at Tufts Medical Center, focuses his research on geriatric psychiatry and neurocognitive disorders, such as Alzheimer’s disease and related dementias, late-life depression, and older adult bipolar disorder.
The world’s first case of a new parasitic infection in humans has been discovered by researchers at The Australian National University (ANU) and the Canberra Hospital after they detected a live eight-centimetre roundworm from a carpet python in the brain of a 64- year-old Australian woman.
Las altas temperaturas y el nivel alto de humedad aumentan el riesgo de sufrir problemas relacionados con el calor, como la deshidratación y la insolación.
A recent study by the University of Eastern Finland and Balettakademien Stockholm found that performing in a dance company and being involved in its activities play a significant role in the identity and disease-related identity negotiation in people with Parkinson’s disease.
Patients living with one of the UK’s most common heart rhythm conditions are 50% less likely to die from a heart attack or stroke than they were at the start of the millennium, new research has found.
John Chappell, a cardiovascular scientist in the Center for Vascular and Heart Research at the Fralin Biomedical Research Institute at VTC, didn't quite believe what he was seeing.
A groundbreaking study published in *Scientific Reports, a Nature portfolio scientific journal, has shed light on the intricate relationship between the sense of presence in virtual reality (VR) environments and cognitive abilities.
Short-lived proteins control gene expression in cells to carry out a number of vital tasks, from helping the brain form connections to helping the body mount an immune defense. These proteins are made in the nucleus and are quickly destroyed once they’ve done their job.
Women with ME/CFS tend to have more symptoms and co-occurring conditions than men, according to initial results from the world’s largest study of the disease.
China and the world are facing severe population aging and an increasing burden of age-related diseases.
Researchers from Indiana University School of Medicine have discovered a neglected brain region that could play a critical role in how likely a person with drug use disorders is to relapse, even after a long withdrawal period. Their findings were published recently in Biological Psychiatry.
Scientists have identified a series of processes that help the brain adapt to damage caused by breakdowns in circuits that govern movement, cognition and sensory perception.
ASD, a complex neurodevelopmental disorder, is known to be linked to altered brain development. However, precise markers that can accurately diagnose ASD at the individual level have been elusive.
The Speech Accessibility Project is almost halfway through its first phase of gathering voice recordings from people with Parkinson’s. Project participant and Parkinson's advocate Ethan Henderson can comment.
Neurons that sense different types of touch are “born” unspecialized but develop specific features based on the skin type they end up innervating.
Millions of Americans were exposed to SARS-CoV-2, the virus that causes COVID-19, early in the pandemic but could not get diagnosed due to testing limitations. Many of those people developed a post-viral syndrome with symptoms similar to those of long COVID.
A Cedars-Sinai study has identified a group of brain cells in laboratory mice that regulate stress-induced feeding and calorie expenditure, with a more pronounced effect in females than in males.
Researchers have identified a way to assess brain activity in sleep that occurs in the earliest stages of Alzheimer’s disease, typically many years prior to developing symptoms of dementia.
En julio, salió al mercado el primer análisis de sangre directo al consumidor diseñado para evaluar el riesgo de un usuario de desarrollar la enfermedad de Alzheimer.
A new study by Indiana University School of Medicine researchers uses more genetically diverse mouse models to study the accumulation and spread of abnormal tau protein deposits in the brain.
Researchers analyzed health information on middle-aged and senior participants in the UK Biobank. They showed that those who took part in adult education classes had a 19% lower risk of developing dementia within five years of follow-up.
In July, the first direct-to-consumer blood test designed to assess a user’s risk for developing Alzheimer’s disease hit the market.
اكتشف علماء مايو كلينك وجامعة ييل، من خلال استخدام نماذج "الدماغ المُصغَّر" البشرية المعروفة باسم العضيات، أن جذور اضطراب طيف التوحد قد تكون مرتبطة باختلال توازن الخلايا العصبية المحددة التي تلعب دورًا حاسمًا في كيفية تواصل الدماغ ووظائفه.
Fewer than half of people worldwide who have already had one heart attack or stroke take daily aspirin to prevent a second one, according to a new study led by researchers at Washington University School of Medicine in St. Louis.
Multiple studies have demonstrated the memory-enhancing effects of melatonin and its derivatives in animal models.
Researchers at RUSH are seeking volunteers to explore how a change in diet may improve brain health after a stroke. The study, called NOURISH — short for Nutrition Effects on Brain Outcomes and Recovery in Stroke After Hospitalization — aims to prevent cognitive and memory decline that is common in stroke survivors.
Erin Wamsley is the Herman N. Hipp Associate Professor of Psychology in Furman University's Department of Psychology and Program in Neuroscience. She was awarded a $562,000 NSF RUI grant to study mechanisms of memory consolidation in offline wakefulness.
New results from researchers at UC San Diego School of Medicine suggest that intermittent fasting could be an effective treatment approach for Alzheimer’s disease.
You’re eating or drinking something frozen, like a snow cone, ice cream, or ice pops – probably a bit too eagerly – and you get one of those sudden-onset, painful headaches known as “brain freeze.” Man, does it hurt, but usually not for long, and it’s not harmful, according to an expert at UT Southwestern Medical Center.
Usando modelos humanos de “minicérebros” conhecidos como organoides, a Mayo Clinic e os cientistas da Universidade de Yale descobriram que as raízes do transtorno do espectro autista podem estar associadas com um desequilíbrio de neurônios específicos que exercem uma função crítica na forma como o cérebro se comunica e funciona.
Utilizando modelos de minicerebros humanos conocidos como organoides, científicos de Mayo Clinic y de la Universidad de Yale han descubierto que las raíces del trastorno del espectro autista pueden estar asociadas a un desequilibrio de neuronas específicas que desempeñan un papel fundamental en la forma en que el cerebro se comunica y funciona.
The Wits Neuroscience Research Lab (NeuRL) is working with an interdisciplinary team of researchers to build an immersive virtual reality laboratory. The team recently welcomed close collaborator Dr Harry Farmer, aSenior Lecturer in Psychology from the University of Greenwich, who delivered a hybrid seminar on how embodiment using virtual reality technologies can change previously held attitudes and beliefs.
Most of us who’ve reached middle age have noticed a slowing in memory and cognition, but scientists don’t have a clear picture of the molecular changes that take place in the brain to cause it. Now, a study in mice has determined that the most pronounced changes occur in the white matter, a type of nervous system tissue that’s integral to transmitting signals across the brain.
In trials, the antipsychotic drug brexpiprazole (Rexulti) failed to provide a clinically meaningful benefit and increased the risk of death. Yet the US Food and Drug Administration (FDA) has fast tracked its approval, making Rexulti the first antipsychotic for treating agitation in elderly patients with dementia.
Lead exposure has long been a known health risk, especially for young children. Research has found that even at low levels, chronic exposure to lead can cause damage to the brain and other organs and cause problems with cognitive and motor skills.
In patients with ALS, the motor dysfunction symptoms usually appear in one part of the body, such as the limbs, and then progress to others. This further suggests that degeneration starts in one type of motor neuron and, thereafter, propagates to other motor-related neurons.
Pioneering neuroscientist at the University of Chicago, Sliman Bensmaia helped develop prosthetic limbs that can restore a realistic sense of touch to amputees and paralyzed patients.
When choosing their behaviour in socially difficult situations, anxious people use a less suitable section of the forebrain than people who are not anxious.
Researchers from Washington University in St. Louis have used ultrasound to nudge rodents into an energy-conserving state that mirrors a natural, hibernation-like survival mechanism known as torpor. The technique could help buy precious time for patients in critical care.
A combination approach of increasing the SIRT3 protein and inhibiting PARPs (poly-ADP ribose polymerase) helps rescue motor endurance of mice modeling the neuromuscular disease spinal bulbar and muscular atrophy (SBMA), also known as Kennedy’s disease, according to a new study by Philadelphia College of Osteopathic Medicine (PCOM) researchers.
Researchers are using mathematical models to better understand the effects of disruptions like daylight savings time, working night shifts, jet lag or even late-night phone scrolling on the body’s circadian rhythms.
New animal research suggests that little-studied brain cells known as astrocytes are major players in controlling sleep need and may someday help humans go without sleep for longer without negative consequences such as mental fatigue and impaired physical health.
Doctors try to improve the life of a four-year-old with a rare genetic disease and other patients like her
Only a small percentage of older adults who are in the early stages of Alzheimer’s disease meet the eligibility criteria to receive new monoclonal antibody treatments, drugs that target amyloid-ß plaques in the brain, an early sign of Alzheimer’s disease. The new research is published in the August 16, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. Clinical trial results for these drugs are only available in people in the early symptomatic stages of the disease, mild cognitive impairment or mild dementia due to Alzheimer’s disease.
Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer’s disease, according to new research from UTHealth Houston.
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