By characterizing the epigenome of direct reprogramming processes, Qian and colleagues discovered common features of direct reprogramming. Particularly, Ascl1, the neuron reprogramming factor, activates a unique set of cardiac genes. Together with As
Therapeutic gene editing based on homology-directed repair (HDR) promises to precisely recombine donor template sequences at programmed double-strand break sites. In this issue, Ferrari et al. report that commonly used AAV donors blunt hematopoietic
Three recent studies from the Zernicka-Goetz and Hanna groups (Amadei et al., 2022; Tarazi et al., 2022; Lau et al., 2022) report the development of mouse embryo-like structures from stem cells. Using a combination of stem cell-derived sources, th
Fibrosis, the pathological end stage of chronic inflammatory diseases, results from extracellular matrix deposition by fibrogenic fibroblasts. In this issue of Cell Stem Cell, Sobecki et al. (2022) develop a novel vaccination-based immunotherapy aga
Kémy Adé, Javier Saenz Coronilla, Dorian Obino, Tobias Weinberger, Caroline Kaiser, Sebastien Mella, Cheng Chen, Lida Katsimpardi, Catherine Werts, Pascal Dardenne, Yvan Lallemand, Elisa Gomez-Perdiguero
Marie Boutet, Piril Erler, Kenta Nishitani, Nicole Couturier, Zheng Zhang, Emeline Barbieux, Erik Guillen, Masako Suzuki, Gregoire Lauvau, Wenjun Guo
Tao Zhang, Sarah E. Noll, Jesus T. Peng, Amman Klair, Abigail Tripka, Nathan Stutzman, Casey Cheng, Richard N Zare, Alexandra Jazz Dickinson
Zhe Wang, Akira Numada, Yusuke Oda, Mototsugu Eiraku
Agata Banach-Latapy, Vincent Rincheval, David Briand, Isabelle Guenal, Pauline Speder
Chuanying Geng, Huixing Zhou, Huijuan Wang, Yanchen Li, Yun Leng, Zhiyao Zhang, Yuan Jian, Guangzhong Yang, Wenming Chen
Gemma Noviello, Rutger A.F. Gjaltema, Edda Schulz
Inayat Batish, Mohammad Zarei, Nitin Nitin, Reza Ovissipour
Gurvir.Virdi Not Provided
Zhichun Chen, Chongchong Xu, Guanglu Li, Zhexing Wen, Jun Liu, Zixu Mao
Russian scientists acquired stable and bright fluorescent protein moxSAASoti, which can change color and intensity of its fluorescence. To achieve this aim, the scientists made point changes in the sequence of the coding gene.
NIBIB-funded researchers have developed an interlinked tissue chip system that can model four mature organs in their perspective environments simultaneously. These multi-organ tissue chips could represent a new way to evaluate diseases or drugs that affect multiple different tissues.
Abdulvasey Mohammed, Priscila Ferreira Slepicka, Benjamin Solomon, Kelsea M Hubka, Michael G Chavez, Christine Y Yeh, Virginia D Winn, Casey A Gifford, Purvesh Khatri, Andrew Gentles, Katja Gabrielle Weinacht
Giulia Coppiello, Paula Barlabe, Marta Moya-Jodar, Gloria Abizanda, Carolina Barreda, Elena Iglesias, Javier Linares, Estibaliz Arellano-Viera, Adrian Ruiz-Villalba, Eduardo Larequi, Xonia Carvajal-Vergara, Beatriz Pelacho, Felipe Prosper, Xabier L. Arangur
Paolo Petazzi, Telma Ventura, Alisha May, Francesca Paola Luongo, Helen Alice Taylor, Nicola Romanò, Lesley Margaret Forrester, Pablo Menéndez, Antonella Fidanza
Shuang Lai, Li Deng, Cong Liu, Xinlun Li, Liyuan Fan, Yushu Zhu, Yiling Yang, Yandong Mu
Yuki Fujisawa, Ming Lu, Daisuke Yamada, Tomoka Takao, Takeshi Takarada
Niccolo Liorni, Alessandro Napoli, Stefano Castellana, Sebastiano Giallongo, Daniela Rehakova, Oriana Lo Re, Irena Koutna, Tommaso Mazza, Manlio Vinciguerra
Brett Stern, Peter Monteleone, Janet Zoldan
The Association of Biomolecular Resource Facilities (ABRF) Executive Board is pleased to announce the approval of several innovative studies to be conducted by ABRF Research Groups in 2023, to address ongoing questions in biomolecular research techniques and methods.
The White House has sounded the alarm about vulnerabilities in the pharmaceutical supply chain. But new research from the Center for Analytics and Business Insights at Olin Business School found that the U.S. actually has the capacity to make the nation’s most essential and critical drugs — yet it's mostly sitting idle.
Sean de la O, Zhe Liu, Sean Chang, Julie B Sneddon
Heather A McCauley, Anne Marie Riedman, Jacob R Enriquez, Xinghao Zhang, Miki Watanabe-Chailland, J. Guillermo Sanchez, Daniel O. Kechele, Emily F. Paul, Kayle Riley, Courtney Burger, Richard A Lang, James M. Wells
Shunya Yagi, Yanhua Wen, Liisa Galea
Emily J Clarke, Emily Johnson, Eva Caamano Gutierrez, Camilla Andersen, Lise Berg, Rosalind Jenkins, Casper Lindegaard, Kristina Uvebrant, Evy Lundgren-Akerlund, Agnieszka Turlo, Victoria James, Stine Jacobsen, Mandy J. Peffers
Nicholas R. Smith, Sidharth K. Sengupta, Patrick Conley, Nicole R. Giske, Christopher Klocke, Brett S. Walker, Noelle McPhail, John R. Swain, Yeon Jung Yoo, Ashley N. Anderson, Paige S. Davies, Nasim Sanati, Theresa N. Nguyen, Kristo
Medeea C Popescu, Naomi L Haddock, Elizabeth B Burgener, Laura S Rojas-Hernandez, Gernot Kaber, Aviv Hargil, Paul Bollyky, Carlos E Milla
Wouter H. van der Valk, Edward S.A. van Beelen, Matthew R. Steinhart, Carl Nist-Lund, John C.M.J. de Groot, Peter Paul G. van Benthem, Karl R. Koehler, Heiko Locher
Xing Feng, Ruifeng Sun, Moonyoung Lee, Xinyue Chen, Shangqin Guo, Huimin Geng, Marcus Müschen, Jungmin Choi, Joao Pedro Pereira
L. Francisco Lorenzo-Martín, Xosé R Bustelo
Mariko Moriyama, Yuko Miyake, Tomomi Degawa, Nobuaki Okumura, Hiroyuki Moriyama
Shahan Mamoor
Shahan Mamoor
Shahan Mamoor
Landslides threaten many lives. A new study suggests we could predict landslides better with electrical measurements of soil.
The Cardiovascular Research Foundation (CRF) is pleased to announce that Puzzle Medical Devices Inc. has won the TCT 2022 Shark Tank Innovation Competition for its novel circulatory support device that is implanted percutaneously in the abdominal aorta. The competition took place during Transcatheter Cardiovascular Therapeutics (TCT), the world’s premier educational meeting specializing in interventional cardiovascular medicine, September 16-19 in Boston. The winner was also presented with the Jon DeHaan Foundation Award for Innovation in Cardiology.
Sowbarnika Ravichandran, Ramalingam Suhasini, Sudiksha Madheswaran Deepa, Divya Bharathi Selvaraj, Jemi Feiona Vergil Andrews, Viruthachalam Thiagarajan, Mahesh Kandasamy
Coral K Wille, Xiaoya Zhang, Spencer Haws, John Denu, Rupa Sridharan
Ardian Ferraj, Peter A Audano, Parithi Balachandran, Anne Czechanski, Jacob I Flores, Alexander A Radecki, Varun Mosur, David S Gordon, Isha A Walawalkar, Evan E Eichler, Laura G Reinholdt, Christine R Beck
Muthu Veeraputhiran, Jennifer Gernat, Naveen Yarlagadda, Milan Bimali, Ellyn E. Matthews
Makoto Onizuka, Tadashi Imanishi, Kaito Harada, Yasuyuki Aoyama, Jun Amaki, Masako Toyosaki, Shinichiro Machida, Eri Kikkawa, Sanetoshi Yamada, Kazuhiko Nakabayashi, Kenichiro Hata, Ken Higashimoto, Hidenobu Soejima, Kiyoshi Ando
Sevim Busra Korkmaz, Selma Erol Aytekin, Huseyin Tokgoz, Sukru Guner, Ismail Reisli, Sevgi Keles
Lisa Kleissl, Anna Redl, Teresa Neuwirth, Ruth Dingelmaier-Hovorka, Ram Pandey, Georg Stary
Saltanat Ualiyeva, Evan R Lemire, Amelia Boyd, Caitlin Wong, Evelyn C Aviles, Alice Maxfield, Rachel Roditi, Nora Barett, Kathleen M Bucheit, Tanya M Laidlaw, Joshua A Boyce, Lora G Bankova, Adam L Haber
BACKGROUNDThe effect of hypoxia on mesenchymal stem cells (MSCs) is an emerging topic in MSC biology. Although long non-coding RNAs (lncRNAs) and messenger RNAs (mRNAs) are reported to play a critical role in regulating the biological character
BACKGROUNDRecent studies have demonstrated that mesenchymal stem cells (MSCs) can rescue injured target cells via mitochondrial transfer. However, it has not been fully understood how bone marrow-derived MSCs repair glomeruli in diabetic kidney
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