Curated News: PNAS

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28-Feb-2018 5:05 PM EST
U CO2 Sensor Network Shows Effects of Metro Growth
University of Utah

In a study published today in Proceedings of the National Academy of Sciences, a team led by atmospheric scientists Logan Mitchell and John Lin report that suburban sprawl increases CO2 emissions more than similar population growth in a developed urban core.

Released: 5-Mar-2018 2:30 PM EST
Arms Races and Cooperation Among Amoebae in the Wild
Washington University in St. Louis

Social amoebae evolve to fight with others but also to die for their kin.

Released: 1-Mar-2018 10:00 AM EST
What Zombie Ants Are Teaching Us About Fungal Infections: Q & A with Entomologists David Hughes and Maridel Fredericksen
NIH, National Institute of General Medical Sciences (NIGMS)

I can still remember that giddy feeling I had seven years ago, when I first read about the “zombie ant.” The story was gruesome and fascinating

26-Feb-2018 10:00 AM EST
Mammoth Data: Researchers Sequence Complete Genomes of Extinct and Living Elephants Pointing to Highly Complex Relationships, Rich Evolutionary History
McMaster University

An international team of researchers has produced one of the most comprehensive evolutionary pictures to date by looking at one of the world's most iconic animal families - namely elephants, and their relatives mammoths and mastodons-spanning millions of years.

Released: 19-Feb-2018 5:05 PM EST
Neurons Fight Back Early in Brain Disease
Vanderbilt University Medical Center

A therapeutic target to preserve vision in glaucoma patients could have treatment ramifications for age-related neurodegenerative disorders like Alzheimer’s and Parkinson’s, according to findings released today in the Proceedings of the National Academy of Sciences (PNAS).

Released: 13-Feb-2018 12:35 PM EST
Scientists Identify Immune Cascade that Fuels Complications, Tissue Damage in Chlamydia Infections
Harvard Medical School

Research in mice pinpoints immune mechanism behind tissue damage and complications of chlamydia infection, the most common sexually transmitted disease in the United States. Separate immune mechanisms drive bacterial clearance versus immune-mediated tissue damage and subsequent disease. Therapies are needed to avert irreversible reproductive organ damage that can arise as a result of silent infections that go untreated.

Released: 12-Feb-2018 4:40 PM EST
UCI-Led Study Identifies ‘Hot Spots’ of Water Quality Violations
University of California, Irvine

While serious violations like those in the Flint, Michigan, crisis are rare, ensuring reliable access to safe drinking water poses challenges for communities across the country, according to a recent study led by the University of California, Irvine.

Released: 8-Feb-2018 4:30 PM EST
Simple Rules Can Help Fishery Managers Cope with Ecological Complexity
University of Washington

A team of ecologists and economists is the first to test whether real-life ecological interactions produce economic benefits for the fishing industry. The results were published online Jan. 29 in the Proceedings of the National Academy of Sciences.

Released: 8-Feb-2018 11:05 AM EST
Research Presents New Information About Flint Water Crisis
Wayne State University Division of Research

Based on a detailed statistical analysis of multiple datasets, the Flint Area Community Health and Environment Partnership (FACHEP) research team found that the majority of Legionnaires’ disease cases that occurred during the 2014-15 outbreak in Genesee County, Michigan

25-Jan-2018 11:05 AM EST
Language Is Learned in Brain Circuits That Predate Humans
Lombardi Comprehensive Cancer Center at Georgetown University

It has often been claimed that humans learn language using brain components that are specifically dedicated to this purpose. Now, new evidence strongly suggests that language is in fact learned in brain systems that are also used for many other purposes and even pre-existed humans, say researchers.

26-Jan-2018 1:05 PM EST
Why Do We Trust, or Not Trust, Strangers? The Answer is Pavlovian
New York University

Our trust in strangers is dependent on their resemblance to others we’ve previously known, finds a new study by a team of psychology researchers.

Released: 24-Jan-2018 3:05 PM EST
Tracing the Evolution of E. Coli
University of Delaware

A team from the University of Delaware and University of California, San Diego recently uncovered new insights about how E. coli bacteria mutate in response to a life-threatening challenge.

Released: 23-Jan-2018 7:05 PM EST
Genetic Lung Disease’s Molecular Roots Identified
Washington University in St. Louis

People with the rare genetic disease primary ciliary dyskinesia suffer repeated lung infections because they lack functional cilia, hairlike structures that sweep mucus through the airways.  Most people have errors in the molecular motor that powers the cilia. But some have errors in non-motor proteins. Now, Washington University School of Medicine in St. Louis researchers report that mutated non-motor proteins cause disease by assembling the motor incorrectly. The findings suggest new routes to drug discovery.

17-Jan-2018 3:00 PM EST
Climate Change and Snowmelt - Turn Up the Heat, but What About Humidity?
University of Utah

changes in humidity may determine how the contribution of snowpack to streams, lakes and groundwater changes as the climate warms. Surprisingly, cloudy, gray and humid winter days can actually cause the snowpack to warm faster, increasing the likelihood of melt during winter months when the snowpack should be growing, the authors report. In contrast, under clear skies and low humidity the snow can become colder than the air, preserving the snowpack until spring.

Released: 19-Jan-2018 12:05 PM EST
Temporary 'Bathtub Drains' in the Ocean Concentrate Flotsam
University of Washington

An experiment using hundreds of plastic drifters in the Gulf of Mexico shows that rather than simply spread out, as current calculations would predict, many of them clumped together in a tight cluster.

Released: 17-Jan-2018 4:15 PM EST
How Your Brain Remembers What You Had for Dinner Last Night
UC San Diego Health

Confirming earlier computational models, researchers at University of California San Diego and UC San Diego School of Medicine, with colleagues in Arizona and Louisiana, report that episodic memories are encoded in the hippocampus of the human brain by distinct, sparse sets of neurons.

12-Jan-2018 3:00 PM EST
X-Rays Reveal ‘Handedness’ in Swirling Electric Vortices
Lawrence Berkeley National Laboratory

Scientists used spiraling X-rays at Berkeley Lab to observe, for the first time, a property that gives left- or right-handedness to swirling electric patterns – dubbed polar vortices – in a layered material called a superlattice.

Released: 15-Jan-2018 3:45 PM EST
Cellular Seismology: Putting Vibrations on the Map
Universite de Montreal

Scientists in Montreal develop a unique technique to map, on a scale of milliseconds, the elasticity of the components inside a cell.

11-Jan-2018 7:05 PM EST
Researchers Develop a Remote-Controlled Cancer Immunotherapy System
University of California San Diego

A team of researchers has developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognize and kill cancer cells.

   
Released: 11-Jan-2018 4:45 PM EST
All in the Family: Focused Genomic Comparisons
Lawrence Berkeley National Laboratory

In the Proceedings of the National Academy of Sciences, a team led by researchers at the Technical University of Denmark, the DOE Joint Genome Institute and the Joint BioEnergy Institute report the first outcome from the large-scale sequencing of 300+ Aspergillus species.

Released: 9-Jan-2018 12:05 PM EST
Industrial Noise Pollution Causes Chronic Stress, Reproductive Problems in Birds
University of Colorado Boulder

A new study by CU Boulder researchers found that blue birds nesting near noisy oil and gas operations have hormonal changes similar to people with PTSD, smaller nestlings and fewer eggs that hatch

3-Jan-2018 3:40 PM EST
‘Hide or Get Eaten,’ Urine Chemicals Tell Mud Crabs
Georgia Institute of Technology

Mud crabs hide for their lives if blue crabs, which prey upon them, pee anywhere near them. Pinpointing urine compounds for the first time that warn the mud crabs of predatory peril initiates a new level of understanding of how chemicals invisibly regulate undersea wildlife and ecosystems.

Released: 3-Jan-2018 7:05 PM EST
Macrophage Nanosponges Could Keep Sepsis in Check
University of California San Diego

Researchers at UC San Diego have developed macrophage "nanosponges"—nanoparticles cloaked in the cell membranes of macrophages—that can safely remove sepsis-causing molecules from the bloodstream. In lab tests, these macrophage nanosponges improved survival rates in mice with sepsis.

   
Released: 3-Jan-2018 3:40 PM EST
Physicists Build Muscle for Shape-Changing, Cell-Sized Robots
Cornell University

A Cornell University team has made a robot exoskeleton that can rapidly change its shape upon sensing chemical or thermal changes in its environment. And, they claim, these microscale machines – equipped with electronic, photonic and chemical payloads – could become a powerful platform for robotics at the size scale of biological microorganisms.

Released: 2-Jan-2018 3:05 PM EST
Spider's Web Inspires Removable Implant to Control Type 1 Diabetes
Cornell University

For the more than 1 million Americans who live with type 1 diabetes, daily insulin injections are literally a matter of life and death. And while there is no cure, a Cornell University-led research team has developed a device that could revolutionize management of the disease.

   
21-Dec-2017 3:05 PM EST
New Hope for Stopping an Understudied Heart Disease in Its Tracks
University of Wisconsin–Madison

Thanks, in part, to pigs at the University of Wisconsin–Madison’s Arlington Agricultural Research Station, scientists now are catching up on understanding the roots of calcific aortic valve disease (CAVD).

Released: 20-Dec-2017 1:05 PM EST
Defending Against Environmental Stressors May Shorten Lifespan
National Institute of Environmental Health Sciences (NIEHS)

A shorter life may be the price an organism pays for coping with the natural assaults of daily living, according to researchers at the National Institutes of Health and their colleagues in Japan. The scientists used fruit flies to examine the relationship between lifespan and signaling proteins that defend the body against environmental stressors, such as bacterial infections and cold temperatures. Since flies and mammals share some of the same molecular pathways, the work may demonstrate how the environment affects longevity in humans.

   
Released: 18-Dec-2017 3:45 PM EST
Brain Lesions and Criminal Behavior Linked to Moral Decision-Making Network
Vanderbilt University Medical Center

When brain lesions occur within the brain network responsible for morality and value-based decision-making, they can predispose a person toward criminal behavior, according to new research by Ryan Darby, MD, assistant professor of Neurology at Vanderbilt University Medical Center (VUMC).

Released: 18-Dec-2017 3:05 PM EST
Flower or Flesh? Genetics Explain Mosquito Preference
Ohio State University

Researchers have found genetic explanations for why most mosquitoes in one species favor nectar over blood. This work could one day lead to strategies to prevent mosquito-borne illness.

14-Dec-2017 11:05 AM EST
Oldest Fossils Ever Found Show Life on Earth Began Before 3.5 Billion Years Ago
University of Wisconsin–Madison

Researchers at UCLA and the University of Wisconsin–Madison have confirmed that microscopic fossils discovered in a nearly 3.5 billion-year-old piece of rock in Western Australia are the oldest fossils ever found and indeed the earliest direct evidence of life on Earth.

Released: 18-Dec-2017 10:05 AM EST
Researchers Repurpose Immune-Activating Cytokine to Fight Breast Cancer
Case Western Reserve University

The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine. In the Proceedings of the National Academy of Sciences, researchers showed triple-negative breast cancer cells are highly vulnerable to interferon-β—a potent antimicrobial that also activates the immune system. The new study shows interferon-β impairs breast cancer cells’ ability to migrate and form tumors. The study also suggests interferon-β treatment could improve outcomes for certain breast cancer patients.

Released: 18-Dec-2017 8:05 AM EST
Is There Structure in Glass Disorder?
Department of Energy, Office of Science

For one of the strongest known materials, calculations clarify a long-standing debate about how atoms pack together.

Released: 14-Dec-2017 10:05 AM EST
Clearing the Air
Argonne National Laboratory

A greater understanding of the dynamics of chemical reactions is leading to better models of atmospheric chemistry. Through this work, scientists are gaining insight into a key chemical able to break down some major air pollutants.

Released: 5-Dec-2017 3:00 PM EST
How to Keep Students in Science
Howard Hughes Medical Institute (HHMI)

Thousands of undergraduates engage in real scientific discovery through HHMI’s Science Education Alliance. A new analysis finds that they are more likely to persist in science than students who take traditional laboratory courses.

   
4-Dec-2017 12:05 PM EST
Men with HPV Are 20 Times More Likely to Be Reinfected After One Year
University of Chicago Medical Center

An analysis of HPV in men shows that infection with one type strongly increased the risk of reinfection of the same type. The study highlights the importance of vaccination for preventing the spread of HPV in young men before they become sexually active and in older men who have already contracted the virus.

30-Nov-2017 7:05 AM EST
New Test Provides Accurate Measure of DNA Damage from Chemical Compounds
Lombardi Comprehensive Cancer Center at Georgetown University

A new biomarker test developed by researchers at Georgetown Lombardi Comprehensive Cancer Center and their colleagues can help predict, with up to 90 percent certainty, which chemical compounds can cause DNA damage that could lead to cancer.

   
30-Nov-2017 4:45 PM EST
High-Stress Childhoods Blind Adults to Potential Loss
University of Wisconsin–Madison

Adults who lived high-stress childhoods have trouble reading the signs that a loss or punishment is looming, leaving themselves in situations that risk avoidable health and financial problems and legal trouble. According to researchers at the University of Wisconsin–Madison, this difficulty may be biological, stemming from an unhelpful lack of activity in the brain when a situation should be prompting heightened awareness. And that discovery may help train at-risk young people to be better at avoiding risk.

   
Released: 27-Nov-2017 3:55 PM EST
Researchers First to Unlock Key Molecular Mystery of Premature Aging Syndromes
Florida State University

New research from Florida State University is beginning to piece together the stubborn puzzle posed by a family of rare and debilitating premature aging disorders.

Released: 27-Nov-2017 3:25 PM EST
New Study Finds Mycobacteria Can Sense Presence of Proteins That Cause Disease
University of Notre Dame

The study from the University of Notre Dame and Michigan State University could help researchers identify how to tone down the ability of mycobacteria to cause disease and help them in treating infection.

   
27-Nov-2017 6:05 AM EST
Decline in Atmospheric Carbon Dioxide Key to Ancient Climate Transition
University of Southampton

A decline in atmospheric carbon dioxide (CO2) levels led to a fundamental shift in the behaviour of the Earth’s climate system around one million years ago, according to new research led by the University of Southampton.

22-Nov-2017 1:20 PM EST
Scientists Identify Key Factors That Help Microbes Thrive In Harsh Environments
University of Maryland Medical Center

Three new studies by University of Maryland School of Medicine scientists have identified key factors that help microbes survive in harsh environments.

Released: 15-Nov-2017 5:05 PM EST
A Structural Clue to Attacking Malaria’s ‘Achilles Heel’
Scripps Research Institute

New research could boost the development of a more potent vaccine against the global killer.

   
Released: 15-Nov-2017 2:45 PM EST
Does this One Gene Fuel Obesity?
University of North Carolina Health Care System

New research from the Research Triangle suggests that variants in a gene called ankyrin-B – carried by millions of Americans – could cause people to put on pounds through no fault of their own.

   
Released: 14-Nov-2017 10:05 AM EST
Twisting Molecule Wrings More Power from Solar Cells
Department of Energy, Office of Science

Readily rotating molecules let electrons last, resulting in higher solar cell efficiency.

Released: 13-Nov-2017 5:05 PM EST
Investment Portfolio Theory Helps Scientists Predict Animal Population Growth
Stony Brook University

A study published in PNAS details a new “landscape portfolio” theory that is based on Markowitz’s “portfolio theory” in economics, melded with ecological landscape theory to predict population growth of living things.

8-Nov-2017 2:25 PM EST
How Much Will We Pay for Something? Depends on the Value of What We’ve Just Encountered
New York University

The value of the products we encounter influences how much we’ll subsequently pay for other items, new neuroscience research has found. The results point to a previously undetected factor that affects consumer behavior.

   
Released: 9-Nov-2017 9:30 AM EST
Wolters Kluwer New Quizzing Tool Delivers Personalized Learning for Millennials and Next Generation Medical Students and Residents
Wolters Kluwer Health: Lippincott

Wolters Kluwer Health unveiled a quizzing engine that delivers personalized learning and on-the-go insights to support how, when and where today’s medical students want to learn. The powerful quizzing tool allows students to track progress, view results and build customized quizzes to focus their training on specific subjects, topics or areas of weakness. It’s an important addition to contemporary medical education, which supports mobile access and tailors content to ensure medical students and residents more easily learn and retain information that prepares them for clinical practice.

   
Released: 8-Nov-2017 3:25 PM EST
Scientists Find Missing Clue to How HIV Hacks Cells to Propagate Itself
University of Chicago

Computer modeling has helped a team of scientists, including several scholars from the University of Chicago, to decode previously unknown details about the "budding" process by which HIV forces cells to spread the virus to other cells. The findings, published Nov. 7 in Proceedings of the National Academy of Sciences, may offer a new avenue for drugs to combat the virus.

   


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