An embargoed UCLA-led study suggests that an intensive, multifaceted online diabetes prevention program is as effective as in-person programs and can make prevention programs more accessible to those at risk for developing diabetes
UC Davis Comprehensive Cancer Center has received a $6.3 million grant from the National Cancer Institute’s (NCI) Center to Reduce Cancer Health Disparities for a 5-year study to tease out why some ethnic and racial minority groups fare worse than whites when they get cancer and to find more precise treatments to improve their chances of survival.
Using a bioinformatics approach, University of California San Diego School of Medicine researchers found that CD4+ T cell’s binding partner, a molecule called MHC-II, may have even more influence on emerging tumors than MHC-I, the better known partner of CD8+ T cells. The finding, published September 20 in Cell, may help researchers improve cancer immunotherapies and predict which patients will respond best.
MyoKardia, a clinical-stage biopharmaceutical company pioneering precision medicine for the treatment of cardiovascular diseases, today announced the launch of the MyoSeeds™ Research Grants Program, a new initiative to support original, independent research in the biology and underlying mechanisms of cardiomyopathies and precision heart disease treatment with the goal of improving the lives of patients.
Most literacy and math educational apps for preschoolers are not designed to help youngsters actually learn, according to a new study from the University of California, Irvine. Few incorporate features informed by evidence-based best teaching practices or age-appropriate in-play guidance.
Scientists know that upward currents of warm air assist birds in flight. To understand how birds find and navigate these thermal plumes, researchers used reinforcement learning to train gliders to autonomously navigate atmospheric thermals. The research highlights the role of vertical wind accelerations and roll-wise torques as viable biological cues for soaring birds. The findings also provide a navigational strategy that directly applies to the development of UAVs.
This Prostate Cancer Awareness Week, urologist shares three things patients are surprised to learn
BlackDoctor.org, the popular online health information resource for African-American consumers, has named Cedars-Sinai to its 2018 Top Hospitals for Diversity List. BlackDoctor.org specifically cited Cedars-Sinai for its strong commitment in promoting equity and inclusion in the health system's operations, programs, services and staffing. The honor recognizes Cedars-Sinai's ongoing commitment to build and sustain excellence in its diverse academic and medical community.
Stephen Hillenburg (‘84, Natural Resources Planning and Interpretation) is best known for making a lighthearted—and significant—contribution to the appreciation of marine life through the creation of the hit animated television series “SpongeBob SquarePants.”
If it’s been a while since you were in college, the rules are changing: Students may now be required to talk to each other, check their cellphones or trade notes. Professors often no longer lecture from a podium. It’s all part of active learning, which flips traditional education on its head to maximize collaboration.
An innovative reading and writing curriculum born at the CSU has changed how English teachers prepare students who aren’t ready for college.
Researchers at University of California San Diego School of Medicine have unraveled new insights into the way cells leverage G-protein-coupled receptors (GPCRs) and their cellular waste disposal systems to control inflammation. The findings, published September 18 in Cell Reports, suggest some existing cancer drugs that inhibit these cellular activities might be repurposed to treat vascular inflammation, which occurs when artery-blocking plaques form in atherosclerosis.
UCLA researchers have discovered genetic similarities between the adult stem cells responsible for maintaining and repairing epithelial tissues — which line all of the organs and cavities inside the body — and the cells that drive aggressive epithelial cancers. Their findings could bring about a better understanding of how aggressive, treatment-resistant cancers develop and progress, and could eventually lead to new drugs for a range of advanced epithelial cancers such as lung, prostate and bladder cancers.
glaucoma does affect reading. Why? First, while glaucoma does affect peripheral vision, it also affects central vision. Glaucoma patients with moderate or severe disease often describe looking through a fog which extends into their central vision.
Scientists continue to unravel links between body weight and the gut microbiome. Now, researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP) report an unexpected finding: mice fed a fatty diet and mannose, a sugar, were protected from weight gain, leaner and more fit—and this effect tracked with changes in the gut microbiome. The study published today in Cell Reports.
Inflammatory bowel disease (IBD), an umbrella term for a number of gut disorders—including ulcerative colitis and Crohn’s disease—remains a clinical challenge. Now, researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), in collaboration with scientists at Technion – Israel Institute of Technology, have identified a protein that drives intestinal inflammation. This finding highlights new opportunities for creating targeted therapeutics. The study published today in Cell Reports.
Researchers at University of California School of Medicine are preparing to launch a novel clinical trial to examine the safety, efficacy and pharmacological properties of cannabis as a potential treatment for adults with essential tremor (ET). Currently, ET is treated using repurposed medications originally developed for high blood pressure or seizures.
Artificial neural networks—algorithms inspired by connections in the brain—have “learned” to perform a variety of tasks, from pedestrian detection in self-driving cars, to analyzing medical images, to translating languages. Now, researchers at the University of California San Diego are training artificial neural networks to predict new stable materials.
UCLA researchers have created a quick and effective mechanism to measure how these circulating tumor cells perform functions that drive cancer.
Each year, nearly 16,000 U.S. children and teens are diagnosed with cancer. But only 4 percent of federal cancer research funding is earmarked to develop new treatments and cures for children battling this heartbreaking disease – an amount that is far below what is actually needed.
On Saturday, October 6, hundreds of hackers are expected to descend upon the University of California San Diego campus to put their collaborative problem-solving capabilities to the test.
Glaucoma is a disease where the optic nerve gets damaged and the main risk factor is elevated eye pressure (also called intraocular pressure, IOP). The only treatment is to lower the IOP.
X-ray experiments at the Department of Energy’s SLAC National Accelerator Laboratory and Lawrence Berkeley National Laboratory have revealed that the pathways lithium ions take through a common battery material are more complex than previously thought.
The American Association of Critical-Care Nurses has selected Patricia Hickey as its 2019 Distinguished Research Lecturer. Hickey is vice president and associate chief nursing officer at Boston Children’s Hospital and assistant professor of pediatrics at Harvard Medical School.
Tais Gorkhover, a principal investigator with the Stanford PULSE Institute, will receive the 2018 LCLS Young Investigator Award, granted to early-career scientists in recognition of exceptional research using the Linac Coherent Light Source (LCLS) X-ray free-electron laser at the Department of Energy’s SLAC National Accelerator Laboratory.
Starting this fall semester, new education reforms are taking place at the CSU. Learn how faculty prepared to hit the ground running with big changes happening on campuses.
Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved by the U.S. Food and Drug Administration for other uses, such as antifungal agents, the breast cancer drug tamoxifen and antidepressant Prozac.
The Nikon Imaging Center, a microscopy center providing researchers with the latest imaging technologies, has opened UC San Diego. The center provides researchers with access to the latest microscopic tools and technologies, including point-scanning and field-scanning confocal, high-content, total internal reflection fluorescence and wide-field fluorescence microscopes.
Astrocytes' important role in brain function suggests they are also involved in disease. Now, scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified an astrocyte subpopulation as the dominant cell type to spring into action in vivo (in a living organism) in a neuroinflammatory disease setting. The study published today in eNeuro.
Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition. By identifying caspase-2’s critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH — and possibly even reverse early symptoms.
Ronald Ferdman, MD, pediatric allergist-immunologist, offers eight tips for parents to help them manage the care of their child with asthma
Research by CSUN professor Adam Swenson finds that physicians tend to size up chronic pain patients in unexpected ways.
Two new studies by scientists at Scripps Research are bringing Ebola virus’s weaknesses into the spotlight, showing for the first time exactly how human and mouse antibodies can bind to the virus and stop infection—not only for Ebola virus, but for other closely related pathogens as well.
California State University (CSU) Chancellor Timothy P. White has appointed Evelyn Nazario to serve as the university's vice chancellor for human resources. Nazario will assume the role as the university's chief human resources officer with the departure of Melissa Bard who will be leaving the university on October 1, 2018.
A new wearable ultrasound patch that non-invasively monitors blood pressure in arteries deep beneath the skin could help people detect cardiovascular problems earlier on and with greater precision. In tests, the patch performed as well as some clinical methods to measure blood pressure. Applications include real-time, continuous monitoring of blood pressure changes in patients with heart or lung disease, as well as patients who are critically ill or undergoing surgery.
Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have found that the anti-malaria drug amodiaquine inhibits the apelin receptor protein, which helps drive the vascularization behind diabetic retinopathy, wet age-related macular degeneration (AMD) and other conditions. Because the drug has been approved to treat malaria for decades, it could move relatively quickly through the pipeline to help patients. The study was published in the journal PLOS ONE.
Researchers at the University of California San Diego say they have dramatically advanced the science of biometric identification, creating a novel technology that can capture the fingerprints of infants and children, even on the first day of birth.
The Keck School of Medicine of USC has received a generous $100,000 donation from PUMA for the Selena Gomez Fund for Lupus Research, two years after the singer/actress established the fund.
Using genetic and pharmacological means, scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) were surprised to find that blocking LDHA had only a limited impact on melanoma cells, since they were able to redirect energy production. Their results identify an alternative growth pathway driven by a molecule called ATF4, revealing new potential targets for drug development. The study was published today in EMBO Journal.
Two to three million years ago, the functional loss of a single gene triggered a series of changes in what would eventually become the modern human species. Researchers at University of California San Diego School of Medicine report on studies of mice engineered to lack the same gene and resulting data that suggest the lost gene may also have contributed to humanity’s well-documented claim to be among the best long-distance runners in the animal kingdom.
Graham Neil George, professor and Canada Research Chair in X-ray Absorption Spectroscopy (XAS) at the University of Saskatchewan, has been chosen to receive the 2018 Farrel W. Lytle Award for his outstanding contributions to synchrotron science at the Department of Energy’s SLAC National Accelerator Laboratory.
The nation’s most commonly used preschool educational curricula – “whole-child” – do not appear to be any more effective at improving children’s academic, social or behavioral outcomes than instructional materials developed by teachers and districts themselves, according to a new study led by the University of California, Irvine.
Ever wonder why you burn fat and heat up when you exercise or shiver? Now, researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have shown that sarcolipin, a small peptide only found in muscles, increases muscle energy expenditure and fat oxidization. The study was published today in the journal Cell Reports.
Ronald G. Victor, MD, a prominent hypertension expert and the first investigator to scientifically prove that thousands of lives could be saved annually if barbers were enlisted to help fight the epidemic of high blood pressure in the African-American community, died Monday, Sept. 10.
Answers to treating muscular dystrophies could lie in better understanding muscle repair—which resembles a delicate cellular dance choreographed by special cells called fibro-adipogenic progenitors (FAPs). Researchers already know these cells have a dark side—they are also responsible for the muscle wasting and scarring that occurs during Duchenne muscular dystrophy (DMD). Now, scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have revealed that FAPs don’t have just one identity—but several distinct identities that emerge during key stages of muscle regeneration. Importantly, the FAPs that drive the symptoms of DMD have defined markers, meaning they could be targeted for drug development. The study was published in Nature Communications.
Researchers from the Keck School of Medicine of USC are looking to technology to help deconstruct expert surgeons’ robotic surgery skills so they can create an objective, standardized way to train the next generation of surgeons.
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