With diabetes raising the risk for Alzheimer’s Disease by 40%, New Yorkers are facing an escalating Alzheimer's epidemic fueled by failures of New York City and State to undertake effective diabetes prevention.
Research shows for the first time an association between the gut microbiota and the brain regions involved in the processing of sensory information from their bodies. Also, the researchers gained insight into the connections among childhood trauma, brain development and gut microbiome composition.
Much is known about flu viruses, but little is understood about how they reproduce inside human host cells, spreading infection. Now, a research team headed by investigators from the Icahn School of Medicine at Mount Sinai is the first to identify a mechanism by which influenza A, a family of pathogens that includes the most deadly strains of flu worldwide, hijacks cellular machinery to replicate.
At a glance: · New study reveals that blood-brain barrier function relies on the balance between omega-3 fatty acids and other lipids in cells that line blood vessels in the central nervous system. · This lipid make-up keeps the barrier closed by inhibiting the formation of vesicles that shuttle molecules across cells, a process known as transcytosis. · Low levels of vesicles are maintained by the lipid transport protein Mfsd2a. · Disrupting Mfsd2a may be a strategy for opening the blood-brain barrier to deliver drugs into the brain.
Vocalization plays a significant role in social communication across species such as speech by humans and song by birds. Male mice produce ultrasonic vocalizations in the presence of females and both sexes sing during friendly social encounters.
Even objective, automated vision testing—using a device called an autorefractor—gives variable results in patients with Down syndrome, reports a study in the May issue of Optometry and Vision Science, the official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.
Neuroscientists at Tufts have discovered a new signaling pathway that directly connects the brain’s NMDA and a7nACh receptors – both associated with learning and memory –– which has significance for development of drugs to treat schizophrenia. Astrocytes are the key elements that link the receptors.
A team of University of Iowa researches has discovered a new connection between two regions of the brain that may help explain how motor skills develop. Working with infant rats, the scientists found that the hippocampus and the red nucleus, part of the brain stem, synchronize during REM sleep. Findings published in the journal Current Biology.
Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center -- the nucleus -- appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.
Many people have become familiar with the FAST acronym for identifying acute stroke symptoms. But a recently expanded version of the acronym can make it easier for those witnessing an acute stroke to identify it in nearly all cases.
A gene mutation may accelerate the loss of memory and thinking skills in people who are at risk for Alzheimer’s disease, according to a study published in the May 3, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology. The gene mutation is called the BDNF Val66Met allele, or just the Met allele.
Researchers at Sunnybrook Health Sciences Centre in Toronto have begun the world’s first clinical trial evaluating the feasibility and safety of opening the blood-brain barrier (BBB) in patients with Alzheimer’s disease (AD) utilizing focused ultrasound.
Scientists report in Neuron the lost function of two genes prevents infant laboratory mice from developing motor skills as they mature into adults. Researchers also suggest in their study that people with certain motor development disabilities be tested to see if they have mutant forms of the same genes. Their data show that neural circuits between the brain’s motor cortex region and the spinal cord did not properly reorganize in maturing mice lacking the genes.
Columbia scientists observed how molecules that regulate chemical signaling in the brain interact with the AMPA receptor, governing brain function.
Researchers found that allocation of rehabilitation services differs by ethnicity, which may help explain why Mexican-Americans have worse outcomes after stroke.
ROCHESTER, Minn. — It’s not often that a fall saves someone’s life. Helen Powell, 74, says that was the case for her. A computerized tomography scan that followed her fall revealed a cancerous brain tumor that led her to Mayo Clinic and surgery using first-in-the-world technology.
Flying a stroke specialist by helicopter to a nearby stroke patient for emergency care is feasible, saves money and, most importantly, gets critical care to patients faster than transporting the patient to a hospital first, according to a single-patient, proof-of-concept study by a Johns Hopkins Medicine research team.
Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego mined the FDA Adverse Effect Reporting System (FAERS) database for depression symptoms in patients taking ketamine for pain. They found that depression was reported half as often among the more than 41,000 patients who took ketamine, as compared to patients who took any other drug or drug combination for pain.
The structure of the social network to which a person belongs could shape how their brain responds to social exclusion, according to a new study led by a Michigan State University researcher.
In a pair of studies published in the journal Neuro-Oncology, UNC Lineberger Comprehensive Cancer Center researchers and collaborators report on the genetic evolution of glioblastoma as it progresses in severity and a potential strategy to treat this often fast-growing brain cancer type.
LifeBridge Health selects Jonathan Ringo, M.D., as president and chief operating officer (COO) of Sinai Hospital of Baltimore.
ORNL aids St. Jude’s brain development research with software to speed processing of microscopy images; bottleneck to breakdown lignin for biofuels may occur at plant cell wall surface; predicting how ecosystems respond to environmental change could be more precise through new process method; through quantum mechanical squeezing, researchers designed new concept to increase resolution of atomic force microscopy
The University of Warwick has started research to understand the cause of brain tumours. A team based at the University’s Warwick Medical School will study brain tumour cells in the lab to understand more about the cell division process, and how it can cause cancer when it goes wrong.
In observance of Stroke Awareness Month, Hackensack Meridian Health Neuroscience is kicking off a series of informative community events, providing expert advice, tips, screenings, and the latest information about stroke prevention and treatments. The events will take place at locations throughout Middlesex, Monmouth and Ocean counties.
April 2017 Headline
Andrew Sloan, MD, Director of the Brain Tumor and NeuroOncology Center at University Hospitals Cleveland Medical Center, presented new data supporting use of the NeuroBlate system for brain lesions at the 2017 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting in Los Angeles on April 26.
Yanqing Sun drew upon both her Eastern heritage and Western experiences to write about parenting and child development.
Dr. David Brody, who is considered one of the world’s foremost researchers on traumatic brain injury and neurodegenerative diseases, has been appointed to the faculty of the F. Edward Hébert School of Medicine at the Uniformed Services University of the Health Sciences (USU), a Department of Defense agency, and will direct the university’s Center for Neuroscience and Regenerative Medicine (CNRM).
– In the United States, someone has a stroke every 40 seconds. Strokes – 80 percent of which are caused by a blood clot that blocks blood flow to the brain – are medical emergencies that require immediate attention.
A new $5 million challenge gift aims to boost scientific research on bipolar disorder, while honoring the legacy of an automotive pioneer who battled the condition during his life.
Ferroelectric tunnel junctions show ability to make strong or weak connections and learn pattern recognition
Sanford Burnham Prebys Medical Discovery Institute (SBP) announces the appointment of three new members to the board of trustees. Joining the board are Donald J. Rosenberg, J.D., Kazumi Shiosaki, Ph.D., and James M. Myers.
Researchers have discovered two genes, known as UNC5C and ENC1, that are associated with aging individuals having better memory and brain function than would be expected, given the amount of pathologies that accumulated in their brains.
An ASU research project is pursuing a method of brain stimulation that may improve learning and retention and boost the performance of troops, athletes, students, and musicians.
The synchronization of brainwaves among students during class reflects how much they like the class and each other, a team of neuroscientists has found.
New research detailing the molecular mechanisms involved in the breakdown of the soft tissue discs of the spine has the potential to help millions suffering the debilitating back pain, and may provide opportunities for advanced, minimally invasive treatments.
Little is known about which specific areas of the brain contribute to a patient’s epileptic network or the roles these different areas play. As a group of researchers in Germany now reports this week in Chaos, one way to get closer to the complex wiring of the human brain is by merging concepts from a timed-based synchronization theory and space-based network theory to construct functional brain networks.
Researchers at Baylor Institute for Rehabilitation and Baylor Scott & White Research Institute received a grant to participate in a nationwide study to improve post-acute care for patients who have suffered a traumatic brain injury.
Johns Hopkins researchers report that an analysis of survey responses and health records of more than 10,000 American adults for nearly 20 years suggests a “synergistic” link between exercise and good vitamin D levels in reducing the risk of heart attacks and stroke
New research from the National Institutes of Health found that pairing the antidepressant amitriptyline with drugs designed to treat central nervous system diseases, enhances drug delivery to the brain by inhibiting the blood-brain barrier in rats. The blood-brain barrier serves as a natural, protective boundary, preventing most drugs from entering the brain. The research, performed in rats, appeared online April 27 in the Journal of Cerebral Blood Flow and Metabolism.
Winner of the Synthes Skull Base Award, John Y.K. Lee, MD, FAANS, presented his research, Folate Receptor Overexpression Can Be Visualized in Real Time During Pituitary Adenoma Endoscopic Transsphenoidal Surgery, during the 2017 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting
Winner of the Columbia Softball Charity Award, Eric M. Thompson, MD, presented his research, Angiogenesis Plays a Critical Role in Group 3 Medulloblastoma Pathogenesis, during the 2017 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.
The U.S. Defense Department is looking for ways to speed up cognitive skills training — the types of skills useful for specialists such as linguists, intelligence analysts and cryptographers — and is awarding University of Florida engineers and neuroscientists up to $8.4 million over the next four years to investigate how to do that by applying electrical stimulation to peripheral nerves as a means of strengthening neuronal connections in the brain.
Parkinson’s disease may start in the gut and spread to the brain via the vagus nerve, according to a study published in the April 26, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology. The vagus nerve extends from the brainstem to the abdomen and controls unconscious body processes like heart rate and food digestion.
Winner of the Robert Florin Award, Michael Bohl, MD, presented his research, Overlapping Surgeries are not Associated with Worse Patient Outcomes: Retrospective Multivariate Analysis of 14,872 Neurosurgical Cases Performed at a Single Institution, during the 2017 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.
Winner of the Integra Foundation Award, Mark W. Youngblood, presented his research, Clinical and Molecular Features of Genomic Subgroups in Meningioma, during the 2017 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.
UW-Madison researchers are part of an effort to develop a low-cost, easy-to-use system that aims to accelerate learning by stimulating nerves in the head and neck to boost neural activity in the brain.
In a first for the Virginia Tech Carilion partnership, a medical school student has been awarded with a Howard Hughes Medical Institute fellowship to devote a year to epilepsy research at the Virginia Tech Carilion Research Institute.
Scientists report in Nature Communications it may be possible to therapeutically fine tune a constantly shifting balance of molecular signals to ensure the body’s peripheral nerves are insulated and functioning normally. In a study published April 26, they suggest this may be a way to treat neuropathies or prevent the development of peripheral nerve sheath tumors. They discovered genetic dysfunction in the HIPPO-TAZ/YAP and Gαs-protein feedback circuit disrupts the balanced formation of the protective myelin sheath.
Winner of the Leksell Radiosurgery Award, Jason P. Sheehan, MD, PhD, FAANS, presented his research, Early vs. Late Gamma Knife Radiosurgery Following Transsphenoidal Surgery for Nonfunctioning Pituitary Macroadenomas: a Matched Multi-center Cohort Study, during the 2017 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right