New hydrogel-based materials that can change shape in response to psychological stimuli, such as water, could be the next generation of materials used to bioengineer tissues and organs, according to a team of researchers at the University of Illinois Chicago.
In an era of required social distancing and stressed medical resources, a virtual clinical environment that allows doctors and nurses to safely practice intubating a simulated COVID-19 patient, among other necessary procedures, could accelerate and enhance training efforts. With the support of a new $654,000 supplement grant, a team of engineers at Rensselaer Polytechnic Institute will develop an artificially intelligent agent called the Virtual Intelligent preceptor for COVID (VIVID), which will prepare teams for surgeries, to intubate patients, and to properly use personal protective gear, without increasing anyone’s risk of exposure.
Research into the gut-brain axis continues to reveal how the brain and gut influence each other’s health and well-being. Now researchers are endeavoring to learn more about gut-brain discourse using a model system built in a lab dish.
The FDA granted emergency use authorization today for an innovative COVID-19 viral antigen test developed with support from NIH’s RADx Initiative.
Engineers have created 3D printed patient-specific models of the aorta that can aid presurgical planning and improve outcomes of minimally invasive valve replacement.
The COVID-19 Testing Impact Calculator is a free resource that shows how different approaches to testing and other mitigation measures, such as mask use, can curb the spread of the virus in any organization.
Researchers at the University of Pittsburgh School of Medicine have combined synthetic biology with a machine learning algorithm to create human liver organoids with blood and bile handling systems. When implanted into mice with failing livers, the lab-grown replacement livers extended life.
Inspired by a parasitic worm that digs its sharp teeth into its host’s intestines, Johns Hopkins researchers have designed tiny, star-shaped microdevices that can latch onto intestinal mucosa and release drugs into the body.
In a groundbreaking new study, researchers at the University of Minnesota, in collaboration with the U.S. Army Combat Capabilities Development Command Soldier Center, have 3D printed unique fluid channels at the micron scale that could automate production of diagnostics, sensors and assays used for a variety of medical tests and other applications. The team is the first to 3D print these structures on a curved surface, providing the initial step for someday printing them directly on the skin for real-time sensing of bodily fluids.
NIH has awarded seven contracts to companies and academic institutions to develop digital health solutions that help address the COVID-19 pandemic.
Researchers created a system that uses CRISPR in a new way. Rather than acting on the genome to create permanent change, their system briefly suppresses genes specific to adenovirus antibody production, just long enough for the virus to deliver its gene therapy cargo unimpeded.
Researchers from the University of Minnesota, with support from Medtronic, have developed a groundbreaking process for multi-material 3D printing of lifelike models of the heart’s aortic valve and the surrounding structures that mimic the exact look and feel of a real patient. These patient-specific organ models, which include 3D-printed soft sensor arrays integrated into the structure, are fabricated using specialized inks and a customized 3D printing process. Such models can be used in preparation for minimally invasive procedures to improve outcomes in thousands of patients worldwide.
The winners of National Institutes of Health’s 9th annual Design by Biomedical Undergraduate Teams (DEBUT) challenge developed simple and low-cost diagnostics and treatments for conditions such as tuberculosis, cervical cancer, birth defects, and onchocerciasis (river blindness).
NIBIB-funded researchers have created nanoparticles for successful gene therapy of a mouse model of macular degeneration. The nanoparticle carriers have the potential to significantly expand the effectiveness of gene therapies for human eye diseases, including blindness.
NIH has launched an ambitious effort to use artificial intelligence, computation, and medical imaging to enable early disease detection, inform successful treatment strategies, and predict individual disease outcomes of COVID-19.
A new center hosted at the University of Chicago — co-led by the largest medical imaging professional organizations in the country — will help tackle the ongoing COVID-19 pandemic by curating a massive database of medical images to help better understand and treat the disease. The work is supported by a $20 million, two-year federal contract that could be renewable to $50 million over five years.
In a groundbreaking new study, researchers at the University of Minnesota have 3D printed a functioning centimeter-scale human heart pump in the lab. The discovery could have major implications for studying heart disease, the leading cause of death in the United States killing more than 600,000 people a year.
Scientists use nanoparticle-delivered gene therapy to limit blinding retinal disease in rodents.
A new technique funded by NIBIB and developed by University of Minnesota researchers allows 3D printing of hydrogel-based sensors directly on the surface of organs, such as lungs—even as they expand and contract.
Scientists at NIBIB have developed new image processing techniques for microscopes that can reduce post-processing time up to several thousand-fold.
A new $2.3 million grant from the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health will support a research effort led by Rensselaer Polytechnic Institute to develop a virtual operating room team training.
Medical physicists at the Mayo Clinic have just made a unique library of computed tomography (CT) data publicly available so that imaging researchers can study, develop, validate, and optimize algorithms and enhance imaging hardware to produce peak-quality CT images using low radiation doses.
Bioengineers have created a blood-drawing robot that performed as well or better than technicians. The device could increase blood draw success from difficult- to-find veins and allow healthcare workers more time to treat patients.
Bioengineers have created a 3D-printed scaffold designed to regenerate complex tissues composed of multiple layers of cells with different biological and mechanical properties.
Sandia National Laboratories has received a $6 million grant from the the National Institutes of Health to build a prototype medical device that would make magnetoencephalography (MEG) — a type of noninvasive brain scan — more comfortable, more accessible and potentially more accurate.
Launching no earlier than March 6 at 11:50 PM EST, the Johns Hopkins University will send heart muscle tissues, contained in a specially-designed tissue chip the size of a small cellphone, up to the microgravity environment of the International Space Station (ISS) for one month of observation.
The National Institutes of Health has launched a $1 million Technology Accelerator Challenge (TAC) to spur the design and development of non-invasive, handheld, digital technologies to detect, diagnose and guide therapies for diseases with high global and public health impact. The Challenge is focused on sickle cell disease, malaria and anemia and is led by NIH’s National Institute of Biomedical Imaging and Bioengineering (NIBIB).
Scientists at Johns Hopkins report they have designed and successfully tested an experimental, super small package able to deliver molecular signals that tag implanted human cancer cells in mice and make them visible for destruction by the animals’ immune systems. The new method was developed, say the researchers, to deliver an immune system “uncloaking” device directly to cancer cells.
Most medicines work by binding to and blocking the effect of disease-causing molecules. Now to accelerate the identification of potential new medicines, bioengineers have created a computer model that mimics the way molecules bind.
A biomedical engineering professor at Binghamton University, State University of New York is trying to find a cure for diabetes from several different angles, and three federal grants totaling nearly $1.2 million will aid her and her research team in that quest.
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