Feature Channels: Neuro

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A new therapy in development for the treatment of midgut neuroendocrine tumors, a rare type of cancer that occurs in the small intestine and colon, shows improved progression-free survival and response rates for patients with advanced disease. Results of the international phase 3 clinical trial of lutetium-177 (177Lu)-Dotatate compared to high-dose octreotide LAR were published in the Jan. 12 issue of the New England Journal of Medicine.

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Decades of psychological research cast doubt Research on eyewitness testimony has shown that false details put forth during an interrogation can lead some people to develop vivid memories of events that never happened. While this “false memory” phenomenon is alive and well, new research suggests that a bit of misinformation also has potential to improve our memories of past events — at least under certain circumstances.

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Dr. Alexander Drofa removed clot in 9-day-old baby using unique method

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The first set of guidelines for the use of fMRI in pre-surgical evaluation of patients with epilepsy have been published in Neurology. The seven-year effort was conducted by a committee commissioned by AAN and led by UAB's Jerzy Szaflarski, M.D., Ph.D.

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Before epilepsy surgery, doctors may consider using brain imaging to locate language and memory functions in the brain instead of the more invasive procedure that is commonly used, according to a guideline published by the American Academy of Neurology in the January 11, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology. It is the first evidence-based guideline that systematically reviewed all evidence for such an evaluation.

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Scientists at the University of Luxembourg have identified a gene that may provide a new starting point for developing treatments for Alzheimer's disease.

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Sedentary older adults with no genetic risk factors for dementia may be just as likely to develop the disease as those who are genetically predisposed, according to a major study which followed more than 1,600 Canadians over five years.

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Experiments in mice by researchers at Johns Hopkins suggest that if the goal is to ease or extinguish fearful emotional memories like those associated with post-traumatic stress disorder, alcohol may make things worse, not better. Results of their study demonstrate, they say, that alcohol strengthens emotional memories associated with fearful experiences and prevents mice from pushing aside their fears.

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NCCN has published NCCN Guidelines for Patients®: Brain Cancer – Gliomas, available today on NCCN.org/patients and NCCN Patient Guides for Cancer mobile app

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In a perspective published January 6, 2017, in Science, Hamilton Farris, PhD, Associate Professor-Research at LSU Health New Orleans Neuroscience Center of Excellence, finds that the key insight of an important study is that perception can drive the evolution of observable traits.

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The devastating 2011 earthquake, tsunami, and resulting nuclear disaster in Japan had a high mental health impact—with some effects persisting several years later, according to a comprehensive research review in the January/February issue of the Harvard Review of Psychiatry, published by Wolters Kluwer.

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More than 12 months after Parkinson's patient Bill Crawford received "DBS Plus," he can walk more easily and is back to leading services at his beloved Porter Memorial Church in Lexington, Ky.

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Soon you can seek mental health advice on your smartphone as quickly as finding a good restaurant.A novel suite of 13 speedy mini-apps called IntelliCare resulted in participants reporting significantly less depression and anxiety by using the apps on their smartphones up to four times a day, reports a new Northwestern Medicine study.

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Vision problems are a common and sometimes lasting consequence of head injuries—from children and teens with sports-related concussions to military personnel with combat-related traumatic brain injury (TBI). New research and perspectives on TBI and vision are presented in the January feature issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.

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Wichita State graduate student Pranita Kaphle is researching the migration of cancer cells in a 3D environment. She is targeting glioblastoma multiforme in the brain, a rapid spreading and aggressive high-grade tumor. Kaphle hopes to pursue a career studying the cancer cells and finding a way to inhibit tumor cell invasion.

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Researchers from the University of California, San Diego, have identified a protein that regulates a gene associated with schizophrenia. The study’s findings have significant implications for schizophrenia treatment.

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Patients who had a diagnosis of Parkinson’s disease with dementia or dementia with Lewy bodies and had higher levels of Alzheimer’s disease pathology in their donated post-mortem brains also had more severe symptoms of these Lewy body diseases during their lives, compared to those whose brains had less AD pathology

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ASRA Member Shalini Shah, MD, of the University of California, Irvine, is the principal investigator of the latest study to be awarded ASRA's Chronic Pain Research Grant.

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A new study shows that older people who followed a Mediterranean diet retained more brain volume over a three-year period than those who did not follow the diet as closely. The study is published in the January 4, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology. But contrary to earlier studies, eating more fish and less meat was not related to changes in the brain.

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The first study of its kind designed to test the effects of a diet on the decline of cognitive abilities among a large group of individuals 65 to 84 years who currently do not have cognitive impairment will begin in January.

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In a new University of Michigan study, gene therapy deployed with immune checkpoint inhibitors demonstrates potential benefit for devastating brain cancer.

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Vitamin D deficiency may increase the risk of chronic headache, according to a new study from the University of Eastern Finland. The findings were published in Scientific Reports

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A study in the American Journal of Critical Care suggests that safe administration of continuous intravenous infusion of hypertonic saline via a peripheral catheter may help avoid unnecessary placement of central catheters, which could lead to fewer associated complications and lower healthcare costs.

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Scientists at the Virginia Tech Carilion Research Institute have discovered that observing fear in others may change how information flows in the brain. The finding in a rodent model may have bearing on people who suffer post-traumatic stress disorder.

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A new study led by scientists at The Scripps Research Institute (TSRI) sheds light on how the brain stores memories. The research, published recently in the journal eLife, is the first to demonstrate that the same brain region can both motivate a learned behavior and suppress that same behavior.

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A study led by researchers at Children’s Hospital Los Angeles demonstrates what lead investigator Bradley Peterson, MD, calls “a critical mass of evidence” of a common underlying lifelong vulnerability in both children and adults who stutter.

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Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration (FDA) that testing in humans may proceed for an investigational new drug after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.

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/PRNewswire-USNewswire/ -- The Institute for Functional Medicine (IFM) is pleased to announce a new collaboration with MPI Cognition, founded by Dale Bredesen, MD, to train clinicians in the treatment of mild cognitive impairment and early Alzheimer's disease. The program is titled Reversing Cognitive Decline: Advanced Clinical Training in Treating MCI and Early Alzheimer's Disease, and the first offering will be March 11-12, 2017, in Huntington Beach, CA.

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New research shows motor abnormalities frequently associated with low birth weight babies could originate due to peripheral nerve defects.

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Dan Iofifescu, MD, MSc, a clinician-scientist specializing in mood disorders, has been recruited to the Psychiatry faculty at NYU Langone Medical Center, furthering the department’s national reputation in diagnosing and managing depression and related disorders.

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Kevin Flanigan, MD, is the new director of the Center for Gene Therapy and the Neuromuscular Disorders program at Nationwide Children’s Hospital.

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A wide range of pre-existing psychiatric and behavioral conditions and the use of psychoactive drugs could be important risk factors leading to long-term use of opioid pain medications, reports a study in PAIN®, the official publication of the International Association for the Study of Pain (IASP). The journal is published by Wolters Kluwer.

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A song is just a song, but as time goes by, something as random as a song’s length could be the difference in whether you miss an important deadline or arrive late for an appointment, suggests time-management research from Washington University in St. Louis.

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Welders can develop Parkinson’s disease-like symptoms that may get worse the longer and more they are exposed to the chemical element manganese from welding fumes, according to a study published in the December 28, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Welders exposed to airborne manganese at estimated levels well under federal safety standards develop neurological problems, according to a study at Washington University School of Medicine in St. Louis. Current safety standards may not adequately protect welders from the dangers of the job.

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Understanding how the nervous system of the roundworm C elegans works will give insights into how our vastly more complex brains function and is the subject of a paper in Nature Methods.

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The 2017 Neuro Film Festival, presented by the American Academy of Neurology, is now accepting video submissions. The Neuro Film Festival, now in its eighth year, is an online video contest that encourages people to share their story about how brain disease has impacted their life or that of a loved one, how their advocacy efforts have influenced change or simply why they are fascinated by the wonders of the brain.

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The researchers said this study might help shed light on sudden infant death syndrome (SIDS) in human babies, which is thought to be associated with dysfunctional airway sensory neurons.

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Researchers at UT Southwestern Medical Center have uncovered the mechanism that cells use to find and destroy an organelle called mitochondria that, when damaged, may lead to genetic problems, cancer, neurodegenerative diseases, inflammatory disease, and aging.

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The secret to reliably diagnosing concussions lies in the brain’s ability to process sound, according to a new study by researchers from Northwestern University’s Auditory Neuroscience Laboratory. Widely considered a crisis in professional sports and youth athletic programs, sports-related concussions have had devastating neurological, physical, social and emotional consequences for millions of athletes.

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Along with increased cheer and festivities during the holidays comes an increased risk of stroke, one of the leading causes of death and disability in the U.S. Patrick D. Lyden, MD, chair of the Cedars-Sinai Department of Neurology, said he sees a significant increase in stroke incidents during December and January, particularly on Christmas Day and New Year’s Day.

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In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment.

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Positive results of an investigational medication study for primary progressive multiple sclerosis were published online in today’s New England Journal of Medicine in a paper led by senior author Jerry Wolinsky, M.D., of McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth).

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After a traumatic brain injury (TBI), people also experience major sleep problems, including changes in their sleep-wake cycle. A new study shows that recovering from these two conditions occurs in parallel. The study is published in the December 21, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Do big-brained creatures steal energy for them from other organs or eat more to supply this expensive tissue? New work in large-brained fish suggests skimping elsewhere is not enough to meet the energy demands of an extreme brain.

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More than 250 people attended the International Society of Neurogastronomy symposium earlier this month, where internationally-renowned pastry chef Taria Camerino was a featured speaker. Camerino is a gastoral synesthete, which means she experiences all five senses as taste.

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University of Michigan researchers find it’s not only risk factors like lower limb strength and precise perception of the limb’s position that determine if a geriatric patient will recover from a perturbation, but also complex and simple reaction times.

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Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer’s disease. Knowing the shape of the molecule — and how that shape may be disrupted by certain genetic mutations — can help in understanding how Alzheimer’s and other neurodegenerative diseases develop and how to prevent and treat them.

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UCLA researchers initiate brain repair following white matter stroke in animals, identifying a possible therapeutic target to combat this common cause of dementia