The St. Jude Children’s Research Hospital VOICES project is the focus of the “A Piece of My Mind” column in the July 22 edition of the Journal of the American Medical Association (JAMA). The project uses contemporary technology to tap an ancient and powerful clinical tool—the patient’s own story—as a way to empower and inspire patients, teach empathy and improve health care.
Chemclin’s Anti-TB assay provides components for in-vitro qualitative determination of Antibody to Mycobacterium Tuberculosis (Anti-TB) in human serum or plasma by an indirect chemiluminescent assay method.
Chemclin’s Anti-TP assay provides components for in-vitro qualitative determination of Antibody to Treponema Pallidum (Anti-TP) in human serum or plasma by a double - antigen sandwich chemiluminescent assay method.
Chemclin’s HIV kits are available for in-vitro qualitative determination of Antibody to Human Immunodeficiency Virus Type 1 and Type 2 (Anti-HIV 1+2) and P24 antigen of HIV in human serum or plasma by a sandwich chemiluminescent assay method.
Men do not engage in riskier behaviors after they are circumcised, according to a study in Kenya by University of Illinois at Chicago researchers.
Among uncircumcised men in Kenya, compensation in the form of food vouchers worth approximately U.S. $9 or $15, compared with lesser or no compensation, resulted in a modest increase in the prevalence of circumcision after 2 months, according to a study published by JAMA.
The annual HIV diagnosis rate in the U.S. decreased more than 30 percent from 2002-2011, with declines observed in several key populations, although increases were found among certain age groups of men who have sex with men, especially young men, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS.
Among adults in the African country of Malawi offered HIV self-testing, optional home initiation of care compared with standard HIV care resulted in a significant increase in the proportion of adults initiating antiretroviral therapy, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS.
HIV-infected patients also infected with hepatitis C virus (HCV) who received a combination of the medications sofosbuvir plus ribavirin had high rates of sustained HCV virologic response 12 weeks after cessation of therapy, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS.
Among heterosexual African couples in which the male was HIV positive and the female was not, receipt of antiretroviral pre-exposure preventive (PrEP) therapy did not result in significant differences in pregnancy incidence, birth outcomes, and infant growth compared to females who received placebo, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS.
In a preliminary study, HIV-infected patients with excess abdominal fat who received the growth hormone-releasing hormone analog tesamorelin for 6 months experienced modest reductions in liver fat, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS.
A multicenter team of researchers report that in a phase III clinical trial, a combination drug therapy cures chronic hepatitis C in the majority of patients co-infected with both HIV and hepatitis C.
New research from UC San Francisco found that 60 percent of the city’s homeless and unstably housed women who are HIV-infected or at high risk to become infected have endured a recent experience of some form of violence.
Douglas Nixon, chair of the Department of Microbiology, Immunology, and Tropical Medicine at the George Washington University School of Medicine and Health Sciences, was published in the Cutting Edge section of the Journal of Immunology for his discovery of an antibody that can neutralize the HIV-1 fossil virus. This may lead to finding a viable immunotherapy option for HIV-1.
The study describes factors believed to contribute to these critical public health issues, with a focus on African American and Latino/Hispanic PLHAs, the racial/ethnic groups most affected by HIV/AIDS.
Scientists may be able to entomb the malaria parasite in a prison of its own making, researchers at Washington University School of Medicine in St. Louis report July 16 in Nature.
HIV, the virus that causes AIDS, has the ability to integrate into the human genome, making it extremely difficult to cure the infection. A new study by scientists at Seattle Children’s Research Institute, University of Washington and Fred Hutchinson Cancer Research Center found that when HIV integrates into genes involved with cancer, these cells tend to reproduce to a greater extent than others HIV-infected cells. The study entitled “Center for Global Infectious Disease Research,” was published on July 10, 2014 in the online edition of the journal Science.
A new study led by Johns Hopkins Bloomberg School of Public Health researchers suggests that getting patients in India quickly evaluated by the right doctors can be just as effective at curbing tuberculosis (TB) as a new, highly accurate screening test.
Kansas State University biochemists have discovered how protein's "hands" enable bacteria to establish infection. The research may help scientists develop targeted treatment and intervention methods.
A University of Kentucky professor and his former student have teamed up to form a company that uses a very unique approach to control a common pest that can carry dangerous diseases.
Scientists have identified a key immune response pathway regulated by zinc that may hold clues to stopping sepsis, one of the leading causes of death in America’s intensive care units.
Doctors have long known that people suffering from influenza are likely to do far worse (or even die) if they get a secondary infection in their lungs or airways. Infection from pneumococcus bacteria, in particular, can lead to pneumonia or a variety of other illnesses that could complicate the recovery of flu sufferers. However, Wistar researchers discovered that pneumococcus often colonizes the respiratory tract without illness and if the order of infection was reversed it could actually protect against severe flu-related illness.
Researchers examine survival rates for healthy mosquitoes and those carrying West Nile virus, under varying environments. The results were complicated, but intriguing.
Scientists have identified a protein that is essential to the survival of E. coli bacteria, and consider the protein a potential new target for antibiotics.
Bacteria found in the bladders of healthy women differ from bacteria in women with a common form of incontinence, according to researchers from Loyola University Chicago Stritch School of Medicine.
Researchers studying critically ill children with traumatic injuries have identified an immune marker that predicts which patients are likely to develop a hospital-acquired infection. The study, published online in June in the journal Shock, is part of several larger efforts that could lead to the clinical implementation of quick-turnaround immune function tests and treatments to prevent or reverse immune system damage following critical illness or injury in pediatric patients.
In an era of increasing concern antibiotic-resistant illness, Case Western Reserve researchers have identified a new pathway to disabling disease: blocking bacteria’s access to iron. The scientists showed how bacterial siderophore captures iron from two supply sources to fan bacterial growth and how the body launches a chemical counterassault.
Research led by the University of Adelaide has provided new insights into how the HIV virus greatly boosts its chances of spreading infection, and why HIV is so hard to combat.
Study finds social/behavioral intervention vastly increased the number of African American and Latino individuals living with HIV/AIDS who enrolled in HIV/AIDS medical studies. Nine out of ten participants who were found eligible for studies decided to enroll, compared to zero participants among a control group.
Research into vaccines for malaria in humans should be guided by the success shown in producing effective vaccines for malaria-like diseases in animals, according to a University of Adelaide study.
A new meta-analysis published online in PLOS ONE by infectious disease and epidemiology specialists from the Perelman School of Medicine at the University of Pennsylvania highlights significant gaps in hepatitis C care that will prove useful as the U.S. health care system continues to see an influx of patients with the disease because of improved screening efforts and new, promising drugs.
An antibiotic therapy known to reduce catheter-related bloodstream infections in hemodialysis patients has been shown for the first time to reduce mortality, according to a Henry Ford Health System study.
Nepal has high rates of HPV infection, which nearly always causes cervical cancer. UAB research looks at the prevalence and a potential screening method.
HIV-infected people diagnosed with cancer are two to four times more likely to go untreated for their cancer compared to uninfected cancer patients, according to a new, large retrospective study from researchers in Penn Medicine’s Abramson Cancer Center and the National Cancer Institute published online ahead of print in the Journal of Clinical Oncology.
Now, a newly reported study by researchers affiliated with New York University’s Center for Drug Use and HIV Research (CDUHR) in the journal PLOS One, shows that HIV infection among heterosexual non-injecting drug users (no hypodermic syringe is used; drugs are taken orally or nasally) in New York City (NYC) has now surpassed HIV infection among persons who inject drugs.
Summer means an increase in bug and insect activity. How do you know which insects are harmful, what diseases they carry and how to safely avoid them? “Mosquitoes and ticks are the two pests you primarily want to avoid because they potentially carry infectious diseases,” says Jennifer Layden, MD, infectious disease specialist at Loyola University Health System. “Ticks can carry Lyme Disease and Rocky Mountain Spotted Fever and mosquitoes can spread West Nile Virus.”
STONY BROOK, NY, JUNE 26, 2014—¬ With the arrival of the warmer summer weather comes tick season, and with that, the threat of Lyme disease. Suffolk County is one of the country’s highest risk areas, so Long Island parents should be aware of the risks of tick-borne disease in children. Saul Hymes, M.D., Assistant Professor, Department of Pediatrics and Director of the Pediatric Lyme and Tick-Borne Disease Center at Stony Brook Children’s, some tips and advice on how to stay healthy this summer.
A novel antibiotic delivery system would exploit small molecules called siderophores that bacteria secrete to scavenge for iron in their environments. Each bacterium has its own system of siderophores, which it pumps across its cell membrane before releasing the iron the siderophores hold. If an antibiotic were linked to one of these scavenger molecules, it would be converted into a tiny Trojan horse that would smuggle antibiotics inside a bacterium’s cell membrane.
Signals from the immune system that help repel a common parasite inadvertently can cause a dormant viral infection to become active again, a new study shows.
The human monoclonal antibody known as m102.4, which has proven effective in protecting against the frequently fatal Hendra virus, has now been shown in studies to protect against the closely related Nipah virus -- the basis of the 2011 movie "Contagion" -- a highly infectious and deadly agent that results in acute respiratory distress syndrome and encephalitis, person-to-person transmission, and greater than 90 percent case fatality rates among humans. The results of the study, conducted by a team of Federal and university scientists, will appear in Science Translational Medicine online: “Therapeutic Treatment of Nipah Virus Infection in Nonhuman Primates with a Neutralizing Human Monoclonal Antibody." The full study will be available following the release of the embargo at 2 p.m. June 25, 2014.
A fungus living in the soils of Nova Scotia could offer new hope in the pressing battle against drug-resistant germs that kill tens of thousands of people every year, including one considered a serious global threat.
University of Florida researchers have found evidence that an influenza A virus can jump from horses to camels – and humans could be next.
“A dropped item is immediately contaminated and can’t really be sanitized,” said Jorge Parada, MD, MPH, FACP, FIDSA, medical director of the Infection Prevention and Control Program at Loyola University Health System. “When it comes to folklore, the ‘five-second rule’ should be replaced with ‘When in doubt, throw it out.’ ”
Differences may end worry that new drug classes based on invertebrate mechanisms could disrupt human immune defenses
Kansas State University veterinarian advises to start mosquito prevention methods now in order to protect yourself and your horse from West Nile virus during the heavy infection season in mid to late summer.
A researcher at Georgia State University is studying a new, biological treatment for bacterial and fungal pathogens that are killing honeybees and bats in record numbers.
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