Feature Channels: Immunology

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With COVID-19 vaccines pushing down costs of mRNA technology, a study in mice from Cummings School of Veterinary Medicine experts sparks hope for next generation treatments and potential applications to developing world and veterinary diseases

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Using publicly available data on COVID variant rates, researchers from the University of Hawai'i are investigating how mutations in the virus' genome impact its ability to spread and weaken immune responses.

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A substance produced by gut microorganisms can lead to scarring and blood vessel damage in patients with scleroderma, a new study suggests. Researchers say they will examine whether drugs or food products, like virgin olive oil, can block the formation of the compound in the gut to treat fibrosis.

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The human body contains 600 to 800 lymph nodes, which are specialised organs that trigger immune responses.

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The latest research and expert commentary on the monkeypox outbreak.

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Un estudio dirigido por los científicos del Centro Oncológico Integral de Mayo Clinic descubrió que la adición de brentuximab vedotina a la quimioterapia estándar mejora la supervivencia general de los pacientes con linfoma de Hodgkin, comparado con la administración de solo la quimioterapia estándar.

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Um estudo conduzido por pesquisadores do Centro de Câncer da Mayo Clinic descobriu que adicionar o brentuximab vedotina ao tratamento quimioterápico padrão aumenta a taxa geral de sobrevida de pacientes com linfoma de Hodgkin, em comparação com o padrão de tratamento atual que usa somente a quimioterapia.

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一项由妙佑医疗国际综合癌症中心的研究人员牵头的研究表明，相比目前单纯采用化疗的标准疗法，在标准化疗疗法中添加brentuximab vedotin可提高霍奇金淋巴瘤患者的总体存活期。

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New findings reveal how recovery progresses following inflammation triggered by injury or illness

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Investigators at Cedars-Sinai have proposed a theory for how SARS-CoV-2, the virus that causes COVID-19, infects the body. Their hypothesis, published in Frontiers in Immunology, could explain why some people still have symptoms long after the initial infection.

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Media are invited to pre-register for the ACAAI Annual Scientific Meeting in Louisville, KY, November 10-14.

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Rutgers Cancer Institute of New Jersey expert shares advice on health and wellness as students transition back into the classroom.

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The immune system of vertebrates is a powerful weapon against external pathogens and cancerous cells. T cells play a curcial role in this context.

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Call them “little pinches” or “the thing that gets you a cool Bugs Bunny Band-Aid,” childhood vaccines offer big rewards. A Penn State Health pediatrician offers advice for new parents.

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Cedars-Sinai investigators have developed a method to help identify which human gut microbes are most likely to contribute to a slew of inflammatory diseases like obesity, liver disease, inflammatory bowel disease, cancer and some neurological diseases.

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The majority of people who were likely infected with the Omicron variant of SARS-CoV-2, the virus that causes COVID-19, didn’t know they had the virus, according to a new study from Cedars-Sinai investigators. The findings are published in JAMA Network Open.

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The immune cells that protect us from infection and cancer seek out a wide array of fuel sources to power their function — including some long thought to be cellular waste products. The findings, published in Cell Metabolism, lay the foundation for future personalized dietary recommendations designed to supercharge the immune system and augment therapies for cancer and other diseases.

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When it comes to COVID-19 immunity, antibodies do not tell the whole story, according to Cedars-Sinai professor of Medicine Stanley C. Jordan, MD.

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As SARS-CoV-2 has evolved and mutated, therapeutic antibodies that worked early in the pandemic have become less effective, and newer variants, especially Omicron, have developed ways to evade the antibodies we make in response to vaccines.

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The laboratory of Hai-Hui “Howard” Xue at the CDI published the findings of the complex and cascading molecular interactions modulating T-cell immunology in the August issue of the journal Nature Immunology.

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Scientists have clarified the cellular mechanisms of asthma. The results open new perspectives for effective therapy of the disease.

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A University of Minnesota assistant professor is part of a team that has developed a new way to effectively deliver vaccines through the nose that could lead to better protection against diseases like HIV and COVID-19.

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Below are some of the latest articles that have been added to the Food Science channel on Newswise, a free source for journalists.

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College of Medicine researchers found that replication protein A works with an ally called the WAS protein to ‘save the day’ and prevent potential cancers from developing.

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A cancer therapy model in which existing medication can be used to degrade for only a required period of time and reduce the protein responsible for programmed cell death has been developed. The team utilizes the small-molecule-assisted shutoff -- or SMASh -- degron system in both cultured cells and mice in vivo. Cancer cell growth was suppressed in wild-type mice.

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We rate this claim as mostly true. Among the ways monkeypox can spread is by "Touching objects, fabrics (clothing, bedding, or towels), and surfaces that have been used by someone with monkeypox," according to the Centers for Disease Control and Protection.

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JMIR Publications recently published "COVID-19 and Vitamin D Misinformation on YouTube: Content Analysis" in JMIR Infodemiology, which reported that although social media platforms, such as YouTube, can be an inexpensive and effective method of sharing accurate health information, inaccurate and misleading information shared on YouTube can be dangerous for viewers.

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Carterra, Inc., the world leader in innovative technologies enabling high-throughput biology, and La Jolla Institute for Immunology (LJI), a globally recognized non-profit research organization dedicated to understanding the power of the immune system to promote human health, announced today that LJI has acquired a Carterra LSA instrument to enhance its antibody screening and characterization work.

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Here are some of the latest articles that have been added to the Drug Resistance channel on Newswise, a free source for journalists.

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Cells in the gut send secret messages to the immune system. Thanks to new research from La Jolla Institute for Immunology (LJI) scientists, we can finally get a look at what they're saying.

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A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai

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Wake Forest Institute for Regenerative Medicine (WFIRM) researchers are using a tumor organoid system to examine the effects of metabolites secreted by bacteria on a specialized immunotherapy – immune checkpoint blockage, a promising cancer treatment development – to determine why some patients don’t respond or develop a resistance to the treatment over time.

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Researchers at Canada's McMaster University have discovered a significant and previously unknown mechanism that many bacteria use to resist antibiotics.

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When we fall ill, we often lose our appetite. This also has an effect on our metabolism: since it is no longer as well supplied with carbohydrates, it switches to burning fat.