Focus: Hidden - Ohio

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Sustained stress erodes memory, and the immune system plays a key role in the cognitive impairment, according to a new study from researchers at The Ohio State University.

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A tumor’s immune response to a single dose of the HER2 inhibitor trastuzumab predicted which patients with HER2-positive breast cancer would respond to the drug on a more long-term basis, according to the results of a study published recently in Clinical Cancer Research.

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For the first time in the U.S., a clinical trial is underway that’s evaluating a device designed to treat diastolic heart failure. The first patient enrolled in the randomized, blinded study is being treated at The Ohio State University Wexner Medical Center.

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For the first time, scientists at The Ohio State University have engineered new calcium receptors for the heart to tune the strength of the heartbeat in an animal model.

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Leukemia cells that are resistant to the common drug daunorubicin consume the drug and die, when the drug is hidden inside capsules made of folded up DNA.

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For women with the most common type of breast cancer, a new way to analyze magnetic resonance images (MRI) data appears to reliably distinguish between patients who would need only hormonal treatment and those who also need chemotherapy. The analysis may provide women diagnosed with estrogen positive-receptor (ER-positive) breast cancer answers far faster than current tests and, due to its expected low cost, open the door to this kind of testing worldwide.

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The Ohio State University Wexner Medical Center and Nationwide Children’s Hospital announce the joint appointment of Dr. W. Kenneth Washburn as director of adult and pediatric transplant programs at each respective hospital, beginning in March.

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For the third-consecutive year, tween retailer Justice (an Ascena Retail Group, Inc. company) will launch a national fundraising effort in their stores to benefit Nationwide Children’s Hospital.

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A new study led by Michael Privitera, MD, professor of the Department of Neurology and director of the Epilepsy Center at the University of Cincinnati Neuroscience Institute, tested two generic lamotrigine (prescription antiepileptic) products and found no detectable difference in clinical effects among patients in the trial. The findings were published this week in an advance online edition of The Lancet Neurology.

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A new journal is challenging established methods in biomedical research publications. Pathogens and Immunity streamlines the current research publication process – a well-recognized source of frustration for biomedical researchers – from one day to five minutes.

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The ocean’s power to rein in carbon and protect the environment is vast but not well-understood. But now, an international team of scientists has begun to illuminate how the ocean plucks carbon from the atmosphere, where it contributes to global warming, and shuttles it to the bottom of the sea.

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Just two years old at the time, Zoey Jones was told she would need a heart and lung transplant for her failing organs, a complication due to the single ventricle heart defect she was born with. She was referred to Nationwide Children’s Hospital where they began to prepare for a transplant, when a second look in the catheterization laboratory (cath lab) led doctors to believe her heart and lungs were strong enough to avoid transplant altogether.

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Case Western Reserve University School of Law is adding a new executive master’s degree program in financial integrity, inspired by increasing demand by financial institutions and government agencies for anti-money laundering experts. The new program will be the first offered in this field by a major research university.

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Treating trauma in juvenile offenders can aid social relationships that help them stay out of trouble, according to a new study by researchers at Case Western Reserve University.

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The new ProMedica Health and Wellness Center houses 13 medical practices as well as diagnostic testing and other outpatient specialty services. Approximately 1,500 patients a day are expected to visit the center.

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Researchers at Case Western Reserve University School of Medicine, UCSF School of Medicine and other institutions have recently uncovered abnormalities in embryonic brain development in mice, including transient embryonic brain enlargement during neuron formation, that are responsible for abnormal adult brain structures and behavioral abnormalities.

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Since its introduction nearly 23 years ago, the popular injectable contraceptive depot medroxyprogesterone acetate (DMPA) has been associated with causing substantial weight gain in some adolescent girls. Without being able to identify or predict which girls will gain weight on the drug, physicians typically counsel all teens receiving DMPA to simply eat less. New research suggests that the message may need to change to “eat better.”

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As hospital leaders continue to feel pressure to improve patient outcomes and reduce costs, a new study reveals one reason why many organizations fall short.

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Fake or low-quality medicines and food supplements are an ongoing global problem in underdeveloped nations, although technology-savvy places, such as the United States, are also not immune. A researcher at Case Western Reserve University is developing a low-cost, portable prototype designed to detect tainted medicines and food supplements that otherwise can make their way to consumers.

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Scientists show they can use electronic medical records and birth information to verify and strengthen an already suspected link between autistic children and pregnant mothers with obesity and diabetes.

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The biggest national game of the year is less than one week away and many families across the country are gearing up for game day celebrations.

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A project at The Ohio State University is testing whether high-tech objects that look a bit like artificial trees can generate renewable power when they are shaken by the wind—or by the sway of a tall building, traffic on a bridge or even seismic activity.

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Three Case Western Reserve University faculty members have received funding to further develop emerging technologies aimed at malaria, cystic fibrosis, and sickle cell anemia.

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New research from the University of Cincinnati (UC) College of Medicine suggests that prenatal exposure to flame retardants and perfluoroalkyl substances (PFASs) commonly found in the environment may have a lasting effect on a child’s cognitive and behavioral development, known as executive function.

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Kids with uncorrected farsightedness lose ground on reading skills before they ever start first grade, a new study has found. The research, led by Marjean Taylor Kulp of The Ohio State University, uncovers evidence that moderately farsighted preschoolers and kindergarten students perform worse in early literacy than children with normal vision.

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Exposure to high levels of small particle air pollution is associated with an increased risk of preterm birth – before 37 weeks of pregnancy, according to a new study published online in the journal Environmental Health.

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Even subtle differences in how you refer to people with mental illness can affect levels of tolerance, a new study has found.

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Spouses ideally could play a key role in helping patients lose pounds and keep them off after weight-loss surgery, but being married might actually work against patients, researchers from The Ohio State University have found. The researchers, led by Megan Ferriby, a graduate student in human sciences, concluded that the impact of weight-loss surgery extends to his or her romantic relationships and likely to the entire family.

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A new scientific statement issued by the American Heart Association underscores knowledge gaps that remain when it comes to women and heart attacks, and outlines the priority steps needed to better understand and treat heart disease in women. The statement, chaired by Dr. Laxmi Mehta, from The Ohio State University Wexner Medical Center, compiles the newest data on symptoms, treatments and the types of heart attacks among women.

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– Teens without homes, many of whom have suffered at the hands of those entrusted with providing them care and kindness, often refuse to seek warmth and nourishment at shelters.

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Physicians have known for years that patients respond differently to vaccines as they age. There may soon be a new way to predict and enhance the effectiveness of vaccinations, in particular the hepatitis B vaccine.

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As they interact with Susan Helper in the classroom and on research, students at Case Western Reserve University are getting a chance to learn first-hand what goes into national economic policy-making at the highest levels. Helper spent the last two years on leave from Weatherhead School of Management, managing a team of about 20 researchers as chief economist at the U.S. Department of Commerce. The year before that, she worked for President Barack Obama as a senior economist with the White House Council of Economic Advisers (CEA).

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Tracking the path of chemotherapy drugs in real time and at a cellular level could revolutionize cancer care and help doctors sort out why two patients might respond differently to the same treatment. Researchers at The Ohio State University have found a way to light up a common cancer drug so they can see where the chemo goes and how long it takes to get there.

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Astronomers have spotted what may be the most powerful supernova ever seen—and discovered a mysterious object at its center.

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The two types of youth gun violence couldn’t be more different, but the ways to prevent them remain largely the same, according to a new report by some of America’s top violence researchers.

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Researchers identified a molecular target and experimental treatment strategy for DNA repair defects behind Fanconi anemia – a complex genetic disorder responsible for birth anomalies, organ damage, anemia and cancer.

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Researchers from Massachusetts Eye and Ear/Harvard Medical School and Case Western Reserve University School of Medicine have led an international effort to identify three genetic associations that influence susceptibility to primary open angle glaucoma — the most common form of adult onset glaucoma and the leading cause of irreversible blindness in the world.

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Public-health experts have long expected that kids who eat more carrots and apples are less likely to eat a lot of candy and fries, but new research is calling that into question.

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A concurrent degree program will allow Case Western Reserve University law students to complete their third year in China, while simultaneously earning an LLM (Master of Laws) degree in Chinese Law at Zhejiang University - Guanghua Law School and a JD from CWRU School of Law. The program also permits qualified students in their fourth year of Guanghua Law School to spend an entire academic year at CWRU School of Law in studies for the LLM in U.S. and Global Legal Studies.