UCLA research finds wide variances in surgeons’ decision to operate or recommend an alternative treatment option, suggesting that it depends as much on how surgeons perceive the world as it does on the patient’s diagnosis.
Recognizing that hospitalized kids’ parents, who are stressed and anxious about their children’s health, need some fun too, the Child Life team at Mattel Children's Hospital UCLA offers sewing classes, Zumba and more.
Cedars-Sinai neuroscience researchers are studying whether extensive changes in lifestyle among patients with mild cognitive impairment can slow the progression of Alzheimer’s disease. The research comes amid a sharp rise in the numbers of people affected by Alzheimer’s disease, the most common form of dementia. The disease affects more than 5 million Americans, but diagnoses are expected to triple by 2050, costing the healthcare system an estimated $1.2 trillion annually.
Recognizing his decades of health care leadership, the Health Policy and Management Alumni Association of UCLA’s Fielding School of Public Health has selected Children’s Hospital Los Angeles President and CEO Paul S. Viviano as its 2016 Leader of Today Honoree.
Getting more exercise, giving up cigarettes and monitoring cholesterol and blood pressure are a few steps Americans can take to reduce their risk of stroke, says Doojin Kim, MD, a neurologist at UCLA Medical Center, Santa Monica who often treats patients who have suffered a stroke, the No. 4 cause of death and the No. 1 cause of adult disability in the U.S.
Becker's Hospital Review announced that Children’s Hospital Los Angeles (CHLA) earned a coveted place in its 2016 edition of its list of "100 Great Hospitals in America."
A new study by a UCLA researcher has found no evidence to link the anti-nausea drug to an increased risk of birth defects. In fact, women with the condition who took Zofran reported fewer miscarriages and pregnancy terminations and higher live birth rates than women with extreme morning sickness who did not take the drug
Tommy Covington is the kind of caretaker that his colleagues admire and his patients and families adore. Covington, a soft-spoken, teddy-bear-like veteran, is a legend at CHLA where he works the night shift (7 pm to 7 am) on the hematology-oncology floor. He and the rest of the CHLA nursing staff will be celebrated during National Nurses Week, May 6-12.
A major type of inflammatory bowel disease (IBD) may be caused in part by genetic variants that prevent beneficial bacteria in the gut from doing their job, according to a new study published today in the journal Science.
A U.S. government agency whose mission is to help save the lives of people around the world living with HIV and AIDS has seen a steep drop in funding for an important part of its budget. The finding, from a UCLA study, could be a cause for concern because many countries rely on the agency to help pay for vital health care services for people with the disease.
The connection between a family’s income and childhood health has been well-established, with lower income linked to poorer health and a greater likelihood of more chronic conditions. Now a new study by UCLA researchers shows that the size of the paycheck is not all that matters when it comes to children’s health risks. So does the amount that a family has tucked away in savings.
Dr. Lonnie Zeltzer, director of the director of the UCLA Pediatric Pain and Palliative Care Program, is a renowned expert on treating chronic pediatric pain. She and her husband, Dr. Paul Zeltzer, have a new book, "Pain in Children and Young Adults: The Journey Back to Normal: Two Pediatricians' Mind-Body Guide for Parents" to help parents understand how help alleviate their child's pain.
LOS ANGELES (April 26, 2016) – The inaugural Children’s Hospital Los Angeles Make March Matter ™ campaign raised $1.3 million, the hospital announced Tuesday. The month-long initiative exceeded its $1 million fundraising goal thanks to 67 local businesses and corporate partners who rallied community participation to give in support of critical, lifesaving care for children in Los Angeles.
Automation expert Thomas B. Sheridan concludes that the time is ripe for human factors researchers to contribute scientific insights that can tackle the many challenges of human-robot interaction.
FINDINGS Researchers from the David Geffen School of Medicine at UCLA found that cardiovascular disease patients who have high muscle mass and low fat mass have a lower mortality risk than those with other body compositions. The findings also suggest that regardless of a person’s level of fat mass, a higher level of muscle mass helps reduce the risk of death.
Researchers at UCLA have that found states that expanded Medicaid coverage under the Affordable Care Act saw a significant increase in rates of health insurance among low-income adults compared with states that did not expand the program. The study, published in the peer-reviewed Annals of Internal Medicine, also found improved quality of coverage, more frequent use of health care, and increased rates of diagnoses for chronic health conditions.
The USC Annenberg School for Communication and Journalism has announced that Robert V. Kozinets has been selected as the Jayne and Hans Hufschmid Chair in Strategic Public Relations and Business Communication.
A Cedars-Sinai research team is one of the first in the nation to test the Personal KinetiGraph (PKG) data logger, which tracks the movements of Parkinson’s patients every two minutes over a period of six-to-10 days. This innovative new tool that resembles a wristwatch could improve the quality of life for patients with Parkinson’s disease and better inform neurologists who treat them.
While we look to invent new medicines to treat cancer, a parallel approach to repurpose existing medicines may be highly effective. Stress, mediated by adrenaline, has been suspected to promote cancer growth and this research study shows that by blocking adrenaline receptors in breast cancers, they are less successful in spreading to and growing in the brain.
Although the second-largest and rather concrete metropolis in the United States might not be anywhere near one's immediate association for a biodiversity hotspot, the fly fauna of Los Angeles is quite impressive. As part of BioSCAN, a project devoted to exploring the insect diversity in and around the city, a team of three entomologists report on their latest discovery - twelve new scuttle fly species. Their study is published in the open access Biodiversity Data Journal.
Researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) have demonstrated that targeting survivin – a protein that inhibits apoptosis or cell death – enhances the effectiveness of chemotherapy in cells and mouse models of retinoblastoma (Rb).
Veterans suffering from mild traumatic brain injury and post-traumatic stress disorder — as well as their families — now have access to highly individualized, intensive treatment that draws on UCLA’s nationally recognized expertise in neurology, neurosurgery, psychiatry and integrative medicine. A new mental health program provided by UCLA Operation Mend is designed to heal the hidden, yet lingering, wounds of war.
Receiving a cancer diagnosis and managing treatments can be a frightening prospect. That’s why many cancer survivors seek physical, emotional and spiritual healing to help recover their good health and wellbeing. Cedars-Sinai’s Restorative Yoga program provides a guiding hand in this journey.
The David Geffen School of Medicine at UCLA and the UCLA Henry Samueli School of Engineering and Applied Science have formed a new center whose mission is to improve the quality and reliability of new health care technologies, reduce the length and cost of hospital stays, and allow more patients to heal in their own homes.
Sit-stand computer workstations are intended to provide a healthier and more comfortable work environment. But how do you find the best setup of workstation components for a standing workstation? And should it be the same as the setup you use when you’re sitting down?
What could be warmer and fuzzier than a cute dog? How about 20 of them gathered together at a ‘pawty’ to celebrate a milestone occasion? That’s what happened when Children’s Hospital Los Angeles declared Monday to be Dog Therapy Appreciation Day. The hospital’s Amerman Family Foundation Dog Therapy Program marked a first by providing 365 consecutive days of dog therapy to CHLA patients, families and staff. The last day without a therapy dog on the CHLA campus was April 10, 2015.
David E. Cobrinik, MD, PhD, of The Vision Center at Children’s Hospital Los Angeles (CHLA) has been awarded a four-year grant totaling $1.665 million from the National Eye Institute of the National Institutes of Health. The grant will support his study seeking to improve understanding of how cone photoreceptors develop.
UCLA researchers found that workouts, in addition to brain games, appear to trigger a protein that restores connections between neurons in young people with schizophrenia.
In a groundbreaking advance, UCLA surgeons and bioengineers have discovered the key to personalized medicine through an artificial intelligence-like technology known as Phenotypic Personalized Medicine (PPM). Until now, personalized medicine has been virtually impossible because the number of possible combinations is nearly infinite. To overcome this challenge, PPM showed that a parabola, or curved line unequivocally represents a patient’s response to drug treatment. In this study, the team successfully individualized immunosuppression to prevent transplant rejection using PPM, significantly improving outcomes compared to control patients. PPM technology is also applicable towards nearly every type of disease, ranging from cancer to infectious diseases.
UCLA researchers have found that a state-of-the-art molecular genetic test greatly improves the speed and accuracy with which they can diagnose neurogenetic disorders in children and adults.
Altered shedding of epithelial cells from the intestinal lining is associated with multiple disorders, ranging from IBD to colorectal cancer. Researchers at CHLA looked at ways shedding and cell regeneration are controlled in healthy intestine, and found that shedding is negatively regulated by EGF.
An investigational stem cell therapy derived from patients’ own blood marrow significantly improved outcomes in patients with severe heart failure, according to a study from the Cedars-Sinai Heart Institute.
A leading cause of the bone-loss disease osteoporosis is hyperparathyroidism. Doctors commonly treat this using a class of prescription drugs called bisphosphonates, which are supposed to strengthen bones. A UCLA study found those drugs actually increase the risk of fracture, meaning that taking them is worse than doing nothing at all. The research also revealed that patients who have surgery to remove the overactive parathyroid glands have fewer subsequent bone fractures.
UCLA researchers have developed a promising method to assess how changes in the immune response can help predict the effectiveness of a new immunotherapy in people with glioblastoma (GBM), the most common and deadly type of brain cancer.
Many parents and grandparents lock away their cleaning supplies and other household chemicals, and are surprised to learn that prescription drugs are actually a leading cause of accidental poisoning in children. Dr. Wally Ghurabi, ER director at UCLA-Santa Monica, offers tips on preventing poisoning in toddlers, teens and tweens.
The Children’s Center for Cancer and Blood Diseases (CCCBD) at Children’s Hospital Los Angeles is one of the first sites in the world to offer a promising new investigational therapy to treat pediatric acute lymphoblastic leukemia (ALL).
A promising new discovery by UCLA scientists could lead to a new method of identifying cancer patients that express high levels of an enzyme and are more likely to respond to cancer treatments.
A new study led by researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) reports that the presence of leptin – a hormone secreted by fat cells that is critical to maintaining energy balance in the body -- inhibits the prenatal development of neuronal connections between the brain and pancreas. The findings could help explain the origin of type 2 diabetes, particularly in children of obese mothers.
Douglas Nordli, Jr., MD, has been named chief of the Division of Pediatric Neurology and co-director of the Neurosciences Center at Children’s Hospital Los Angeles (CHLA). Dr. Nordli will also serve as a vice chair of Neurology at the Keck School of Medicine of the University of Southern California.
A UCLA-led study has for the first time shown that microRNAs, specifically the microRNA known as miR-34, can sit silently in an inactive state in a cell waiting for a signal to turn it on. The discovery turns on its head the long-held notion that a microRNA when made is always already activated and ready to work, and shows for the first time that microRNAs can be controlled in a way similar to proteins, waiting for stress signals to turn them on.
Expanding the use of recycled water would reduce water and energy use, cut greenhouse gas emissions and benefit public health in California — which is in the midst of a severe drought — and around the world. A new study by the UCLA Fielding School of Public Health, published online March 17 in the American Journal of Public Health, found that recycled water has great potential for more efficient use in urban settings and to improve the overall resiliency of the water supply.
Cedars-Sinai research scientists have found that immune cells in the brain play a direct role in the development of amyotrophic lateral sclerosis, or ALS, offering hope for new therapies to target the neurodegenerative disease that gradually leads to paralysis and death.
Tracy C. Grikscheit, MD, of The Saban Research Institute of Children’s Hospital Los Angeles receives $7.1 million grant from the California Institute of Regenerative Medicine Translational Research program to develop a cellular therapy for the treatment of nerve disorders of the digestive system.
A new study by UCLA researchers has revealed how patterns of gene mutations and expression in a melanoma tumor before starting anti-PD-1 immunotherapy may forecast whether the tumor would shrink or the patient would derive survival benefits.