Cleveland Clinic researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut. The research, published in the September issue of Nature Medicine, was led by Stanley Hazen, M.D., Ph.D.
A new clinical trial shows that consuming crickets can help support the growth of beneficial gut bacteria and that eating crickets is not only safe at high doses but may also reduce inflammation in the body.
八月份的Mayo Clinic Proceedings杂志上发表的一项初步研究显示，对于一些人来说，尽管他们坚持严格的饮食和锻炼方案，其肠道细菌可能是他们无法成功减肥的原因。
A high-fat diet may promote the growth of pancreatic cancer independent of obesity because of the interaction between dietary fat and cholecystokinin (CCK), a digestive hormone. In addition, blocking CCK may help prevent the spread of pancreatic tumors to other areas of the body (metastases).
Endocrinologists at Beth Israel Deaconess Medical Center (BIDMC) have shown for the first time that brown fat can exert control over skeletal muscle function.
Para algumas pessoas, as bactérias intestinais podem ser responsáveis pela incapacidade de perder peso, apesar da prática de dietas e exercícios rigorosos, sugere um estudo preliminar publicado na edição de agosto da Mayo Clinic Proceedings.
After a successful, two-year pilot project that helped patients reverse their metabolic syndrome with lifestyle changes, the William G. McGowan Charitable Fund is expanding the Eat, Love, Move (ELM) program to five cities through a six-year clinical trial, totaling $9 million in grants to Rush University Medical Center.
A preliminary study published in the August issue of Mayo Clinic Proceedings suggests that, for some people, specific activities of gut bacteria may be responsible for their inability to lose weight, despite adherence to strict diet and exercise regimens.
Increasing healthy brown fat might help weight management and reduce symptoms of diabetes. Columbia Engineers have developed a simple, innovative method to directly convert white fat to brown fat outside the body and then reimplant it in a patient. The technique uses fat-grafting procedures commonly performed by plastic surgeons, in which fat is harvested from under the skin and then retransplanted into the same patient for cosmetic or reconstructive purposes.
In a study published in the August issue of Diseases of the Colon & Rectum, investigators from the University of Alabama at Birmingham sought to answer this question. While it has been long recognized that heavy patients are at higher risk of complications after surgery, Dr. Wahl and his colleagues wanted to find out whether there was a difference whether a patient was merely pudgy or downright obese.
What do patients really want? These are Important questions that doctors at the University of Vermont have tried to answer. In the August issue of Diseases of the Colon & Rectum, Dr. Wrenn and his colleagues surveyed 167 patients who had undergone a colorectal resection between 2009 and 2015.
Mice fed a fattening diet develop new liver circadian rhythms that impact the way fat is accumulated and simultaneously burned. The team found that as liver fat production increases, surprisingly, so does the body’s ability to burn fat. These opposing physiological processes reach their peak activity each day around 5 p.m., illustrating an unexpected connection between overeating, circadian rhythms, and fat accumulation in the liver.
A clinical trial is currently underway to evaluate the predictive values of the STELLUX® Chemiluminescence Calprotectin ELISA for the diagnosis of inflammatory bowel diseases (IBDs), specifically Crohn's disease (CD) and ulcerative colitis (UC). The clinical trial will evaluate the use of the assay to aid in the differentiation of IBD from irritable bowel syndrome (IBS) when used in conjunction with other diagnostic testing.
Researchers with UNC Lineberger’s Carolina Cancer Screening Initiative, in collaboration with the Mecklenburg County Health Department in Charlotte, examined the impact of mailing tests to more than 2,100 people insured by Medicaid who were not up-to-date with colorectal cancer screening.
ALPCO, a leading producer of research and clinical immunoassays, announced it will feature its therapeutic drug monitoring (TDM) ELISA portfolio at the AACC’s 70th Clinical Lab Expo July 31-August 2 in Chicago.
Kombucha (pronounced kom-BOO-cha) can help restore the body’s natural microbiome and improve overall health, but it’s important to make informed choices about kombucha sources and consumption.
Ludwig Cancer Research and the Cancer Research Institute (CRI) announce the initiation of a clinical trial to evaluate the combination of ONCOS-102, an experimental anti-tumor virotherapy, with the checkpoint blockade antibody IMFINZI® (durvalumab) for advanced ovarian and colorectal cancers.
A clinical trial to evaluate the combination of ONCOS-102, an experimental anti-tumor virotherapy, with the checkpoint blockade antibody IMFINZI® (durvalumab) for advanced ovarian and colorectal cancers has been initiated.
Over 80 colorectal cancer advocates will hike to Quandary Peak near Breckenridge, Colorado on Monday, July 16 to raise awareness.
• The ultimate goal of basic biomedical research is to better the lives of patients through prevention, control or cure of disease. • Crossing that gap between the lab and bedside is difficult to achieve. • One great need for better treatment is diabetes, a disorder that afflicts one of every 10 U.S. adults and doubles the risk of early death.
NIBIB-funded researchers at the Massachusetts Institute of Technology have created an ingestible sensor to non-invasively monitor indicators of disease in the stomach and intestines.
Mount Sinai researchers use data science and genomics to help determine best treatment options for specific types of disease
Nonalcoholic fatty liver disease, or NAFLD, which affects roughly 100 million Americans, costs the United States healthcare system $32 billion annually, according to a first-of-its-kind study by Intermountain Healthcare researchers on the economic impact of the disease.
Experts provide on-site complimentary skin cancer and healthy heart screenings
The American College of Gastroenterology is pleased to announce that its Monograph on Management of Irritable Bowel Syndrome (IBS) was published this week in The American Journal of Gastroenterology, the College’s flagship journal. Access the Monograph: https://rdcu.be/19yQ
To make sure that good ideas to enhance healthcare are not lost due to a lack of resources, a growing number of centers at Penn Medicine organize forums to pitch ideas to improve medical devices and technology, hold annual competitions to fund studies to improve patient care while keeping costs down, and sponsor seed grants for programs focused on patients who need individualized tailoring of their treatment. This last category is where precision medicine comes in, which is designed to enhance care for particular groups of patients, based on their genetic background, patient history, and unique diagnosis.
A research team led by Iowa State's Balaji Narasimhan and affiliated with the Nanovcaccine Institute based at Iowa State is studying nanovaccines for treating pancreatic cancer. The study is supported by a $2.67 million grant from the National Cancer Institute of the National Institutes of Health.
Georgetown-led investigators have found that a fairly simple test significantly improves the identification of bladder tumors that will likely become invasive.
Drs. Kenneth Shroyer and Luisa Escobar-Hoyos receive $500,000 from PanCAN to advance research
In preclinical experiments, Laurie Harrington and colleagues have discovered a subset of immune cells that create and sustain chronic inflammatory bowel disease. These cells could become potential therapeutic targets to ameliorate or cure Crohn’s disease and ulcerative colitis.
Researchers at Washington University School of Medicine in St. Louis have found that immune cells called macrophages can trigger smooth muscle contractions in the intestinal tract, independent of nerve cells.
For the 12th year in a row, NewYork-Presbyterian Hospital ranks in more pediatric specialties than any other New York metro area hospital in U.S. News & World Report’s “Best Children’s Hospitals.” The 2018-19 rankings are published online today.
Using a new tool they call FluVision, University of Wisconsin-Madison researchers are able to witness influenza infection in a living animal in action. It helps them better understand what happens when a virus infects the lungs and the body responds.
Cedars-Sinai has launched an initiative to accelerate the development of novel drugs, devices and therapies aimed at improving treatments for patients with gastrointestinal and metabolic diseases. Physician-scientists and others in the Medically Associated Science and Technology (MAST) Program are focusing their research expertise on disorders of the microbiome. This naturally occurring ecosystem of single-cell organisms—including bacteria, fungi, viruses and archaea—lives within the human gut.
A new study provides a platform for predicting how microbial gut communities work and represents a first step toward understanding how to manipulate the properties of the gut ecosystem. This could allow scientists to, for example, design a probiotic that persists in the gut or tailor a diet to positively influence human health.
En los pacientes diagnosticados con cáncer de páncreas, la glucosa sanguínea puede estar elevada hasta tres años antes del diagnóstico de cáncer, muestran los resultados de un estudio realizado por investigadores de Mayo Clinic y publicado en la revista Gastroenterology.
Pacientes diagnosticados com câncer pancreático podem desenvolver níveis elevados de glicose até três anos antes do diagnóstico do câncer, segundo os resultados de um estudo realizado por pesquisadores da Mayo Clinic e publicado no periódico Gastroenterology.
روتشستر، مينيسوتا. - يمكن أن يُعاني المرضى الذين تم تشخيص إصابتهم بسرطان البنكرياس من ارتفاع مستويات السكر في الدم حتى ثلاث سنوات قبل تشخيص السرطان، وذلك وفقًا لنتائج دراسة أجراها الباحثون في Mayo Clinic وقاموا بنشرها في مجلة Gastroenterology.
据Mayo Clinic研究人员发表在《胃肠病学杂志》 （Gastroenterology）上的研究结果，被诊断为胰腺癌（pancreatic cancer）的患者在癌症诊断前长达三年的时间里会有血糖升高。
West Virginia University researchers are working to improve screening rates for the state, which has one of the highest incidences of colorectal cancer and one of the lowest screening rates in the nation.
روتشستر، مينيسوتا. — هناك ستة من الجينات الوراثية تحتوي على طفرات جينيّة يُمكن أن يتوارثها أفراد الأسرة الواحدة وتزيد بشكل كبير من خطر تعرُّض الشخص للإصابة بسرطان البنكرياس. وذلك وفقًا لأحـد البحوث الصادرة عن Mayo Clinic والمنشورة في إصدار التاسع عشر من يونيو من JAMA. على الرغم من ذلك، فقد اكتشف الباحثون وجود تلك الطفرات الوراثية في مرضى لا تُعاني عائلاتهم من أي تاريخ سابق للإصابة بسرطان البنكرياس، ولذلك فإنهم يوصون بإجراء اختبارات جينيّة لجميع مرضى سرطان البنكرياس كمعيار جديد للرعاية.
根据6月19日在《美国医学会杂志》（JAMA.）上发表的一项Mayo Clinic的研究报告，六个基因含有可能在家系中传递的突变，这大大增加了一个人患pancreatic cancer的风险。 然而，由于研究人员在没有胰腺癌家族史的患者中也发现了这些基因突变，他们建议新的医疗标准来对所有胰腺癌患者进行基因检测。
ROCHESTER, Minn. — Six genes contain mutations that may be passed down in families, substantially increasing a person’s risk for pancreatic cancer. That's according to Mayo Clinic research published in the June 19 edition of the JAMA. However, because researchers found these genetic mutations in patients with no family history of pancreatic cancer, they are recommending genetic testing for all pancreatic cancer patients as the new standard of care.
An analysis of small molecules called “metabolites” in a blood sample may be used to determine whether a person is following a prescribed diet, scientists at Johns Hopkins Bloomberg School of Public Health have shown.
Researchers at Rutgers Cancer Institute are exploring the combination of a new anti-cancer vaccine with an immunotherapy drug approved for use in other forms of cancer to determine if the combined treatment can prompt a patient’s natural defenses (the immune system) to attack their cancer and improve their survival.
Results Do Not Support Routine Use of This Expensive Drug
Research published in JAMA Internal Medicine found that tamsulosin does not significantly effect patient-reported passage or capture of kidney stones.
Like everyone, people with type 2 diabetes and obesity suffer from depression and anxiety, but even more so. Researchers at Joslin Diabetes Center now have demonstrated a surprising potential contributor to these negative feelings – and that is the bacteria in the gut or gut microbiome, as it is known.
The incidence of anal cancer continues to rise. Despite making the headlines with Farrah Fawcett, people are still reluctant to discuss this important cancer. The majority of patients with this cancer are cured by a combination of treatment of radiation and chemotherapy.
Physicians from the University of Vermont Medical Center in Burlington undertook a prospective, randomized, double-blinded, placebo-controlled trial to see whether preemptive analgesia could help reduce pain and narcotic use following common anal rectal surgical procedures.
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