Curated News: JAMA

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17-Jun-2020 10:15 AM EDT
10 Percent of Patients Continue to Use Opioids Three to Six Months After Heart Surgery
Perelman School of Medicine at the University of Pennsylvania

Nearly 10 percent of patients who are prescribed opioid medications following heart surgery will continue to use opioids more than 90 days after the procedure, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

15-Jun-2020 4:00 PM EDT
Children with developmental disabilities more likely to develop asthma
University of Texas Health Science Center at Houston

Children with developmental disabilities or delay are more at risk of developing asthma, according to a new study published in JAMA Network Open led by public health researchers at The University of Texas Health Science Center at Houston (UTHealth) as part of the Center for Pediatric Population Health.

Released: 16-Jun-2020 6:00 AM EDT
Most Gender Dysphoria Established by Age 7, Study Finds
Cedars-Sinai

Gender dysphoria manifests early in childhood and can persist for years before patients undergo counseling and treatment, a Cedars-Sinai study has found. The findings also reveal that untreated gender dysphoria can result in poor quality of life for transgender people, beginning in childhood and lasting throughout adolescence and adulthood.

Released: 15-Jun-2020 4:30 PM EDT
Encouraging First Report of Systemic Delivery of Micro-dystrophin Gene Therapy in Children with Duchenne Muscular Dystrophy
Nationwide Children's Hospital

Researchers from Nationwide Children’s Hospital have published in JAMA Neurology results from the first four patients treated in the first clinical trial of systemic delivery of micro-dystrophin gene therapy in children with Duchenne muscular dystrophy (DMD) – and initial findings suggest that the therapy can provide functional improvement that is greater than that observed under the standard of care.

Released: 9-Jun-2020 4:25 PM EDT
Use of Emergency Departments Plummets During COVID-19
Michigan Medicine - University of Michigan

A new commentary highlights the dramatic decline in emergency department visits during the COVID-19 pandemic and what could be causing the decrease.

Released: 9-Jun-2020 2:05 PM EDT
Study: Mixed Progress in Efforts to Reduce Low Value Breast Cancer Surgery
Michigan Medicine - University of Michigan

A U-M review found national Choosing Wisely recommendations to reduce overtreatment in early stage breast cancer weren’t consistently followed.

Released: 8-Jun-2020 3:05 PM EDT
COVID-19 in nursing homes: A tale of two pandemics
Cornell University

Epidemiological models of COVID-19 that are used to guide policies on social distancing measures should take into account the special dynamics of the coronavirus’s spread in nursing homes and other long-term care facilities, according to researchers at Cornell University and Weill Cornell Medicine.

Released: 4-Jun-2020 6:10 PM EDT
FIRE-SCLC analysis: Largest ever study of first-line radiosurgery for brain metastases from small cell lung cancer
University of Colorado Cancer Center

The international First-line Radiosurgery for Small-Cell Lung Cancer (FIRE-SCLC) analysis led by University of Colorado Cancer Center researchers and published today in JAMA Oncology shows no overall survival benefit from whole-brain radiation compared with radiosurgery in patients with small cell lung cancer.

Released: 4-Jun-2020 2:10 PM EDT
Universal Preoperative COVID-19 Screening Improves Safety by Identifying Otherwise Asymptomatic Pediatric Surgical Patients
Children's Hospital of Philadelphia

Universally screening pediatric patients for COVID-19 before they undergo surgical procedures has allowed hospitals to improve safety by identifying all patients who test positive for the virus, half of whom have no symptoms, according to new research led by Children’s Hospital of Philadelphia (CHOP). The study, which analyzed universal screening procedures at CHOP and two other major children’s hospitals, found that screening patients for COVID-19 allowed hospitals to ensure patients and physicians were not exposed to the virus.

Released: 3-Jun-2020 12:05 PM EDT
Survey Finds Large Increase in Psychological Distress Reported Among U.S. Adults During the COVID-19 Pandemic
Johns Hopkins Bloomberg School of Public Health

A new survey conducted during the pandemic by researchers at the Johns Hopkins Bloomberg School of Public Health and the SNF Agora Institute at Johns Hopkins University found a more-than-threefold increase in the percentage of U.S. adults who reported symptoms of psychological distress—from 3.9 percent in 2018 to 13.6 percent in April 2020.

3-Jun-2020 9:00 AM EDT
Cognitive behavior therapy tops other psychotherapies in reducing inflammation
University of California, Los Angeles (UCLA), Health Sciences

A review of 56 randomized clinical trials finds that psychological and behavioral therapies may be effective non-drug treatments for reducing disease-causing inflammation in the body.

Released: 2-Jun-2020 5:40 AM EDT
Mental health of young physicians in China during COVID-19 outbreak
JAMA - Journal of the American Medical Association

Anxiety, depression, mood and fear of workplace violence were assessed in a group of young physicians in China before and during the COVID-19 outbreak.

28-May-2020 1:05 PM EDT
People with Type 1 Diabetes Spend About $2,500 a Year in Health Care Costs
Michigan Medicine - University of Michigan

Adults and children with type 1 diabetes will spend an average of $2,500 a year out-of-pocket for health care - but insulin isn't always the biggest expense - new research suggests

28-May-2020 5:40 PM EDT
Study in Chinese doctors shows mental toll of caring in the time of COVID-19
Michigan Medicine - University of Michigan

They worked in hospitals hundreds of miles from the epicenter of COVID-19. But hundreds of young Chinese doctors in a new study still experienced a sharp drop in mood, a rise in depression and anxiety symptoms, and a doubling of their fear of workplace violence, in the first month of the coronavirus pandemic.

Released: 29-May-2020 1:40 PM EDT
Study finds surge in hydroxychloroquine/chloroquine prescriptions during COVID-19
Brigham and Women’s Hospital

A new study by investigators from Brigham and Women's Hospital examines changes in prescription patterns in the United States during the COVID-19 pandemic.

27-May-2020 1:05 PM EDT
Electronic Health Records Fail to Detect Up to 33% of Medication Errors
University of Utah Health

Despite improvements in their performance over the past decade, electronic health records (EHRs) commonly used in hospitals nationwide fail to detect up to one in three potentially harmful drug interactions and other medication errors, according to scientists at University of Utah Health, Harvard University, and Brigham and Women’s Hospital in Boston.

Released: 28-May-2020 5:10 PM EDT
Mental health outcomes among health care workers during COVID-19 pandemic in Italy
JAMA - Journal of the American Medical Association

Symptoms of posttraumatic stress disorder, depression, anxiety and insomnia among health care workers in Italy during the COVID-19 pandemic are reported in this observational study.

Released: 28-May-2020 3:50 PM EDT
Users of high-potency cannabis four times more likely to report associated problems
University of Bristol

Users of high-potency cannabis are four times more likely to report associated problems, and twice as likely to report anxiety disorder, than users of lower-potency strains, according to new research from the University of Bristol.

22-May-2020 12:05 PM EDT
Follow-up Treatments After Opioid Overdose Rare Among Insured Patients
Perelman School of Medicine at the University of Pennsylvania

Of nearly 6,500 commercially insured patients treated in EDs nationwide for an overdose or other opioid-related medical complications, only 16 percent accessed opioid use disorder (OUD) medications or another form of treatment within three months of the ED visit.

Released: 26-May-2020 4:05 PM EDT
Researchers Find No Benefit for Treatment Used to Avoid Surgery for Abdominal Aortic Aneurysm
University of Maryland Medical Center

A new landmark study by researchers at the University of Maryland School of Medicine (UMSOM) found that patients with a vascular condition, called abdominal aortic aneurysm, received no benefits from taking a common antibiotic drug to reduce inflammation.

Released: 21-May-2020 11:30 AM EDT
Weekly Tip Sheet: Research News from Johns Hopkins Medicine NOT Related to COVID-19
Johns Hopkins Medicine

Tip sheet with latest Johns Hopkins research news NOT related to COVID-19. Stories: more women & seniors needed in cholesterol drug trials, improving medical care quality for homebound seniors & 2020 JHM Science Writers Boot Camp goes virtual.

Released: 19-May-2020 11:45 AM EDT
Why having a national health information technology infrastructure could help save lives
University of Texas Health Science Center at Houston

Real-time data about health and health care during the COVID-19 pandemic can help contain the virus but has been difficult to obtain. A new paper published in JAMA explores the concept of a national health information technology (IT) infrastructure to provide up-to-date patient information in public health emergencies, which can then be used in planning and containment efforts.

   
Released: 14-May-2020 1:50 PM EDT
Assessment of deaths from COVID-19, seasonal influenza
JAMA - Journal of the American Medical Association

Publicly available data were used to analyze the number of deaths from seasonal influenza deaths compared with deaths from COVID-19.

Released: 13-May-2020 11:30 AM EDT
MSK Kids Study: Children with Cancer are Not at a Higher Risk for COVID-19 Infection or Morbidity
Memorial Sloan Kettering Cancer Center

Researches from MSK Kids at Memorial Sloan Kettering Cancer Center (MSK) found that children with cancer are not at a higher risk of being affected by COVID-19.

11-May-2020 11:00 AM EDT
Children Face Risk for Severe Complications and Death from COVID-19
Rutgers University-New Brunswick

Children, teens and young adults are at greater risk for severe complications from COVID-19 than previously thought and those with underlying health conditions are at even greater risk, according to a study coauthored by a Rutgers researcher. The study, published in JAMA Pediatrics, is the first to describe the characteristics of seriously ill pediatric COVID-19 patients in North America.

Released: 7-May-2020 2:35 PM EDT
Olanzapine may help control nausea, vomiting in patients with advanced cancer
Mayo Clinic

Olanzapine, a generic drug used to treat nervous, emotional and mental conditions, also may help patients with advanced cancer successfully manage nausea and vomiting unrelated to chemotherapy. These are the findings of a study published Thursday, May 7 in JAMA Oncology.

Released: 6-May-2020 11:50 AM EDT
High Reliance on Urgent Care Centers May Disrupt Primary Care in Children
Ann and Robert H. Lurie Children's Hospital of Chicago

A study of over 4 million children and adolescents in the U.S. enrolled in Medicaid found that those who rely on urgent care centers for more than a third of their outpatient health care needs had fewer visits to primary care providers. This may result in missed opportunities for preventative services, such as vaccinations, and identification and management of chronic conditions, such as obesity or asthma. Findings were published in JAMA Network Open.

Released: 4-May-2020 11:05 AM EDT
Study Shows Need for New Focus in Anti-Vaping Efforts for Teens & Young Adults
Michigan Medicine - University of Michigan

They know it’s addictive, linked to dangerous lung diseases, and delivers more nicotine than the cigarettes it’s supposed to replace. But the social aspects of vaping drives young people to use e-cigarettes, according to nearly two-thirds of teens and young adults in a new study.

21-Apr-2020 12:05 PM EDT
Very low-dose Avastin effective for preventing blindness in preterm infants
NIH, National Eye Institute (NEI)

Babies born prematurely who require treatment to prevent blindness from retinopathy of prematurity (ROP) could be treated with a dose of Avastin (bevacizumab) that is a fraction of the dose commonly used for ROP currently. Results from the dose-finding study were published April 23 in JAMA Ophthalmology. The study was conducted by the Pediatric Eye Disease Investigator Group (PEDIG) and supported by the National Eye Institute (NEI), part of the National Institutes of Health.

Released: 22-Apr-2020 5:20 PM EDT
New heart attack testing protocol expedites treatment in ER
UT Southwestern Medical Center

A new protocol using highly sensitive blood tests to determine whether someone is having a heart attack

Released: 22-Apr-2020 12:55 PM EDT
Majority of U.S. States and Territories Do Not Require Day Care Providers to Inform Parents of Firearms on Premises
Johns Hopkins Bloomberg School of Public Health

Home- and center-based child care providers are not required by most states or U.S. territories to inform parents when guns are stored on the premises, according to a new study from researchers at Johns Hopkins Bloomberg School of Public Health.

   
17-Apr-2020 4:55 PM EDT
Pulse Oximetry Monitoring Overused in Infants with Bronchiolitis
Children's Hospital of Philadelphia

Monitoring blood oxygen levels with continuous pulse oximetry is being overused in infants with bronchiolitis who do not require supplemental oxygen, according to a study by researchers at Children’s Hospital of Philadelphia (CHOP). The researchers found the use of continuous pulse oximetry occurred frequently and varied widely among hospitals in their sample, despite national recommendations advising against the practice.

Released: 20-Apr-2020 11:45 AM EDT
Rutgers Expert Discusses How to Manage Chronic Pain, Opioid Addiction During COVID-19
Rutgers University-New Brunswick

Many people trying to manage their pain and addiction have lost their support programs due to COVID-19. A Rutgers expert in Emergency Medicine discusses how patients can manage the disease during the coronavirus crisis.

   
13-Apr-2020 5:20 PM EDT
Prescribing an overdose: A chapter in the opioid epidemic
Mayo Clinic

Research indicates that widespread opioid overprescribing contributed to the opioid epidemic. New research shows that this dangerous trend has apparently been coupled with another: inappropriate use of high-potency opioids.

Released: 6-Apr-2020 10:50 AM EDT
Curbing the Rising Toll of Adults with Complex Care Needs
University of Pennsylvania School of Nursing

Data show that the number of people with clinically complex health and social needs is growing. Programs designed to support these adults have fallen short and the healthcare system is becoming overtaxed by these “super-utilizers”.

Released: 3-Apr-2020 5:50 PM EDT
Medicare Changes May Increase Access to TAVR
Michigan Medicine - University of Michigan

The number of hospitals providing TAVR could double with changes to Medicare requirements. Researchers see reason for both excitement and concern.

Released: 2-Apr-2020 8:00 AM EDT
Device That Tracks Location of Nurses Repurposed to Record Patient Mobility
Johns Hopkins Medicine

By repurposing badges originally designed to locate nurses and other hospital staff, Johns Hopkins Medicine scientists say they can precisely monitor how patients in the hospital are walking outside of their rooms, a well-known indicator and contributor to recovery after surgery.

   
Released: 30-Mar-2020 4:05 PM EDT
Investigating SARS-CoV-2 transmission in public bath center in China
JAMA - Journal of the American Medical Association

This case series reports a cluster-spreading event in Huai'an (about 435 miles northeast of Wuhan) in Jiangsu Province, China, where a patient with SARS-CoV-2 may have transmitted the virus to eight other healthy individuals through bathing in a public bath center.

26-Mar-2020 2:35 PM EDT
COVID-19 linked to cardiac injury, worse outcomes for patients with underlying heart conditions
University of Texas Health Science Center at Houston

COVID-19 can have fatal consequences for people with underlying cardiovascular disease and cause cardiac injury even in patients without underlying heart conditions, according to a review published today in JAMA Cardiology by experts at The University of Texas Health Science Center at Houston (UTHealth).

Released: 26-Mar-2020 12:05 PM EDT
When Prostate Cancer Recurs, Adding Hormone Therapy to Radiation May Harm Men with Low PSA Levels
Michigan Medicine - University of Michigan

A secondary analysis of the Radiation Therapy Oncology Group (RTOG) 9601 phase 3 randomized clinical trial finds the benefit of hormone therapy varies depending on a patient’s PSA level.

24-Mar-2020 11:00 AM EDT
Intense Form of Radiation Slows Disease Progression in Some Men with Prostate Cancer That Has Spread
Johns Hopkins Medicine

Highly focused, intense doses of radiation called stereotactic ablative radiation (SABR) may slow progression of disease in a subset of men with hormone-sensitive prostate cancers that have spread to a few separate sites in the body, according to results of a phase II clinical trial of the therapy.

23-Mar-2020 1:10 PM EDT
Survey Data Confirm Increases in Anxiety, Depression, Suicidal Thinking Among U.S. Adolescents Seeking Mental Health Care
Johns Hopkins Bloomberg School of Public Health

Nationwide survey data on more than 230,000 U.S. adolescents over the period 2005 to 2018 suggest that anxiety, depression, suicidal thoughts, and other “internalizing” problems account for an increasing share of the adolescent mental health burden, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health and Columbia University.

Released: 25-Mar-2020 9:35 AM EDT
Breast Cancer Screening Costs High, Benefits Uncertain, for Women in 40s
Yale Cancer Center/Smilow Cancer Hospital

There are substantial costs associated with breast cancer screenings for U.S. women in their 40s, a new Yale Cancer Center-led study finds, and these costs vary widely by region.

Released: 24-Mar-2020 2:05 PM EDT
Is step count associated with lower risk of death?
JAMA - Journal of the American Medical Association

Researchers looked at whether taking more steps and higher intensity stepping were associated with reduced risk of death in this observational study that included almost 4,900 adults (40 and over) who wore a device called an accelerometer to measure their step count and step intensity (steps/minute).

19-Mar-2020 1:00 PM EDT
National study finds diets remain poor for most American children; disparities persist
Tufts University

A study of national dietary trends over 18 years finds some improvements in the diets of U.S. children, but the majority still have a poor-quality diet. Disparities persisted or even worsened, finds the study published in JAMA and led by researchers at Tufts.

16-Mar-2020 2:35 PM EDT
Most Mass Shootings Occur Closest to Hospitals without Verification to Treat Trauma
Children's Hospital of Philadelphia

In an analysis of 2019 mass shootings and hospital locations, researchers at Children’s Hospital of Philadelphia (CHOP) found that the closest hospital to more than 70% of mass shootings was a non-trauma center, where sudden, high casualty loads were more likely to overwhelm capacity and trauma-specific care options may have been limited. They also found that in more than half of mass shooting events, the nearest pediatric trauma center was more than 10 miles away.



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