Curated News: JAMA

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On February 20, 2020, a young man in the Lombardy region of Italy was admitted with an atypical pneumonia that later proved to be COVID-19. In the next 24 hours there were 36 more cases, none of whom had contact with the first patient or with anyone known to have COVID-19. This was the beginning of one of the largest and most serious clusters of COVID-19 in the world. Despite aggressive containment efforts, the disease continues to spread and the number of affected patients is rising. The case-fatality rate has been very high and is dominated by very old patients. This Infographic shows the most recent statistics emerging from Italy regarding the country’s experience with COVID-19.

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New data analysis could change smoking policies worldwide to protect non-smokers and reduce their risk

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A new study examines the factors associated with a potentially missed diagnosis of appendicitis in children and adults in the emergency department.

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Mount Sinai research highlights the need for more hearing checks among groups at high risk for falls

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In a new study published today in JAMA, a team of researchers at Beth Israel Deaconess Medical Center (BIDMC) evaluated how health outcomes for low-income older adults who are dually enrolled in both Medicare and Medicaid have changed since the early 2000s.

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What if there was a tool to help with faster, more accurate diagnosis of both psychogenic seizures and epilepsy? And what if this tool was simpler and less expensive than video EEG, and available almost everywhere?

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The net cost of prescription drugs – meaning sticker price minus manufacturer discounts – rose over three times faster than the rate of inflation over the course of a decade, according to a study published today in JAMA. It’s the first to report trends in all brand name net drug costs in the U.S.

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Racial and ethnic minority children and adolescents with cancer have a higher risk of death than non-Hispanic white children and adolescents, with evidence for larger disparities in survival for more treatable cancers, finds a new study from the Brown School at Washington University in St. Louis.“The results suggest that there are modifiable racial and ethnic disparities in childhood cancer survival,” said Kim Johnson, associate professor and senior author of “Associations Between Race/Ethnicity and US Childhood and Adolescent Cancer Survival by Treatment Amenability,” published Feb.

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Doctors who use drugs that target antibiotic-resistant bacteria as a first-line defense against pneumonia should probably reconsider this approach, according to a new study of more than 88,000 veterans hospitalized with the disease. The study found that pneumonia patients given these medications in the first few days after hospitalization fared no better than those receiving standard medical care for the condition.

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Decreased folate levels in the bloodstream have been associated with an increased risk of cardiovascular mortality in patients with rheumatoid arthritis, shedding light on why those patients are more susceptible to heart and vascular disease, according to research published today in JAMA Network Open by experts at The University of Texas Health Science Center at Houston (UTHealth).

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Having twins from IVF or other related procedures quadruples the chance that a baby may have congenital heart problems.

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Cannabis use continues to increase in popularity among adults 65 years of age and older in the United States, according to a new study from NYU Grossman School of Medicine.

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Black or white, man or woman, providers got similar satisfaction and confidence scores from simulated patients in new research with implications for quality reporting

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A Polygenic Risk Score — a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients — has been found not to be a useful predictive biomarker for disease risk, according to a Vanderbilt study published in the Journal of the American Medical Association.

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In a new study, a team of BIDMC researchers evaluate how hospitals awarded for high quality cardiovascular care by the AHA/ACC performed under federal value-based programs.

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Research from Rutgers Cancer Institute of New Jersey shows administering the immunotherapy drug pembrolizumab together with chemotherapy given at the same time as radiation treatment (chemoradiation) is safe and tolerable as a first-line therapy for patients with stage 3 non-small cell lung cancer (NSCLC).

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. Em um novo artigo publicado em 4 de fevereiro pela revista JAMA, os pesquisadores da Mayo Clinic descrevem os benefícios da terapia de ventilação não invasiva em casa, que exerce uma pressão positiva nas vias aéreas em dois níveis, ou BiPAP, para vários pacientes com doença pulmonar obstrutiva crônica (DPOC).

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在2月4日JAMA发布的一篇新论文中，Mayo Clinic的研究人员描述了家庭无创通气治疗对许多慢性阻塞性肺疾病(COPD)患者的益处，其中包括一种被称为双水平气道正压(BiPAP)的治疗。 该团队确定了许多益处，包括降低死亡率、减少住院次数、降低插管风险、改善气短症状和减少急诊次数。

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In einer neuen, am 4. Feb. in JAMA veröffentlichten Arbeit beschreiben Forscher von Mayo Clinic die Vorzüge einer nicht-invasiven Beatmungstherapie zu Hause ― die einen Typ umfasst, der auch als BiPAP bezeichnet wird ― für viele Patienten mit chronisch obstruktiver Lungenkrankheit (COPD).

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Dans un nouvel article publié le 4 février dans JAMA, les chercheurs de Mayo Clinic décrivent les avantages de la thérapie de ventilation non invasive à domicile ; celle-ci comprend un dispositif appelé dispositif à pression positive biniveau, ou BiPAP, destiné à de nombreux patients atteints de bronchopneumopathie chronique obstructive (BPCO).

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More than 10,000 uninsured patients sought care at Texas emergency departments for lifesaving kidney dialysis in 2017, incurring more than $21.8 million in hospital costs, according to researchers from UTHealth.

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The old story of a farmer trying to get a stubborn mule to pull a wagon by dangling a carrot in front of its nose, or hitting its rump with a stick, may not seem to have much to do with the practice of medicine. But a new study suggests that when it comes to making the best use of health care dollars, it will take a combination of carrots and sticks to move things forward.

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Traditional cardiovascular risk factors often assessed in an annual physical, such as blood pressure, cholesterol levels, diabetes, and smoking status, are at least as valuable in predicting who will develop coronary heart disease (CHD) as a sophisticated genetic test that surveys millions of different points in DNA.

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The highest-earning nonprofit hospitals in the United States provided less charity care to patients than lower-earning hospitals did, relative to the facilities’ respective profits, according to a new study.

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A study from UAB published in JAMA Surgery on Feb. 12 indicates that use of surgical jackets and head covers known as bouffants in operating rooms does not reduce the incidence of surgical site infections.

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The most common type of heart disease ― coronary artery disease ― affects 6.7% of adults and accounts for 20% of 2 in 10 deaths of adults under age 65. The condition builds over time as inflammation and cholesterol-containing plaques settle in the heart's arteries, where they can eventually cause narrowing and blockages that lead to a heart attack.

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A Rutgers-led study in JAMA Network Open, found substantial differences between top-cited ob-gyn articles that were published in non-specialty journals compared to those published in ob-gyn journals.

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Juul may have influenced high school students’ perception of vaping such that some Juul users do not consider themselves e-cigarette users, a Rutgers study finds.

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In a new Cleveland Clinic-led study published in JAMA Oncology, researchers show that a testosterone-related genetic variant – HSD3B1(1245C) – is associated with more aggressive disease and shorter survival in men with metastatic prostate cancer.

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In the largest study of skin cancer rates among gay, lesbian or bisexual individuals, investigators from Brigham and Women's Hospital report important differences in skin cancer prevalence among sexual minorities.

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En un nuevo trabajo publicado en JAMA, los investigadores de Mayo Clinic describen los beneficios para muchos pacientes con enfermedad pulmonar obstructiva crónica (EPOC) de una terapia domiciliaria y no invasiva para ventilación pulmonar, que incluye al tipo conocido como presión positiva de dos niveles sobre las vías respiratorias , o BiPAP.

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As if recovering from surgery wasn’t hard enough, a new study shows that one in five operations could result in an unwelcome surprise: a bill for hundreds or thousands of dollars that the patient didn’t know they might owe. On average, that potential surprise bill added up to $2,011. That’s on top of the nearly $1,800 the average privately insured patient would already owe after it paid for most of the costs of their operation.

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Survival may more than double for adults with glioblastoma, the most common and deadly type of brain tumor, if neurosurgeons remove the surrounding tissue as aggressively as they remove the cancerous core of the tumor.  This discovery, reported in a retrospective study headed by researchers at UC San Francisco, is welcome news for those in the glioblastoma community, which celebrated its last breakthrough in 2005 with the introduction of the chemotherapy drug temozolomide.

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Hospitals, doctors and Medicare Advantage insurance plans that care for some of the most vulnerable patients are not reimbursed fairly by Medicare, according to recent findings in JAMA.

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Health insurance costs weigh heavily on the minds of many middle-aged adults, and many are worried for what they’ll face in retirement or if federal health policies change, according to a new study. More than a quarter of people in their 50s and early 60s lack confidence that they’ll be able to afford health insurance in the next year, and the number goes up to nearly half when they look ahead to retirement.

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Six months after discharge, smartphone users were 32 percent more likely to continue sending health data to researchers than those using wearables

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Women with early stage breast cancer who test positive for an inherited genetic variant are not always receiving cancer treatment that follows current guidelines, a new study finds.

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Research from Washington University in St. Louis shows a nontrivial rate of children as young as 9- and 10- years old are thinking about suicide. How their families interact - or don't - may play a role.

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In a new paper published Feb. 4 in JAMA, Mayo Clinic researchers describe the benefits of in-home noninvasive ventilation therapy ― which includes a type referred to as bilevel positive airway pressure, or BiPAP ― for many patients with chronic obstructive pulmonary disease (COPD). The team identified a number of benefits, including reduced mortality, fewer hospital admissions, lower risk of intubation, improved shortness of breath, and fewer emergency department visits.

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Jeremy Robbins, MD, a cardiologist at BIDMC, discusses how altering the intensity of your workout or trying a new activity may benefit your cardiovascular and mental health.

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Eating two servings of unprocessed red meat, processed meat or poultry a week has been linked to an increased risk of cardiovascular disease.

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Getting covered by health insurance may have a major impact on a low-income person’s ability to get a job or enroll in school, according to a new study. The percentage of low-income people enrolled in Michigan’s Medicaid expansion program who had jobs or were enrolled in school jumped six points in one year, while employment rates in the state remained flat.

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Researchers from The University of Texas MD Anderson Cancer Center have shown that a decision aid delivered through tobacco quitlines effectively reaches a screening-eligible population and results in informed decisions about lung cancer screening.

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State laws that regulate e-cigarette sales and usage may lower their use in states where those laws have been implemented, according to a new observational study from the University of Iowa published this week by the journal JAMA Network Open.

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Mount Sinai Cardiologists Talk Prevention for American Heart Month

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Nearly 2 of every 5 women of reproductive age in the U.S. live in counties where Catholic hospitals have a high market share, according to a new analysis. Catholic hospitals do not provide certain reproductive health options.