BACKGROUNDThe treatment of acute respiratory distress syndrome (ARDS) complicated by sepsis syndrome (SS) remains challenging. AIMTo investigate whether combined adipose-derived mesenchymal-stem-cells (ADMSCs)-derived exosome (EXAD) and ex
BACKGROUNDPelvic organ prolapse (POP) involves pelvic organ herniation into the vagina due to pelvic floor tissue laxity, and vaginal structure is an essential factor. In POP, the vaginal walls exhibit abnormal collagen distribution and dec
BACKGROUNDTraumatic brain injury (TBI) is characterized by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. Stem cell tra
BACKGROUNDValidation of the reference gene (RG) stability during experimental analyses is essential for correct quantitative real-time polymerase chain reaction (RT-qPCR) data normalisation. Commonly, in an unreliable way, several studies u
Mesenchymal stem/stromal cells are potential optimal cell sources for stem cell therapies, and pretreatment has proven to enhance cell vitality and function. In a recent publication, Li et al explored a new combination of pretreatment condi
The stem cell pre-treatment approaches at cellular and sub-cellular levels encompass physical manipulation of stem cells to growth factor treatment, genetic manipulation, and chemical and pharmacological treatment, each strategy having adva
Researchers at Washington University in St. Louis can more effectively study mutations that cause heart disease by putting cells through their paces.
The Korea Research Institute of Standards and Science (KRISS) has developed the world’s first organoid culture method capable of accurately assessing human toxicity of nanomaterials.
The researchers hope to one day target this T cell population via drug therapy. "These cells may be a very important target for treating ulcerative colitis and perhaps other autoimmune diseases..."
Developmental biologist and stem cell investigator David Traver, PhD, has been named director of a new developmental biology and regenerative pediatrics center at Cedars-Sinai Guerin Children’s.
Immunotherapy, a type of cancer treatment that uses a person’s own immune system to attack cancer cells, is continuing to transform cancer treatment and care.
Clive Svendsen, PhD, executive director of the Board of Governors Regenerative Medicine Institute and professor of Medicine and Biomedical Sciences at Cedars-Sinai, is developing new treatments and models for amyotrophic lateral sclerosis (ALS) using stem cells.
Researchers at Brigham and Women’s Hospital and Dana-Farber Cancer Institute found significant uptake and scalability in phone-based “PATH” intervention to improve psychological well-being in blood cancer patients, according to new study in JNCCN.
Researchers have developed — and shared — a process for creating brain cortical organoids — essentially miniature artificial brains with functioning neural networks
Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence cell survival, proliferation, and differentiation.
UCLA scientists have identified a protein that not only enables blood stem cells to self-renew in a lab dish, but also allows these expanded cells to function effectively after being transplanted into mouse models.
A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.
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