A team of investigators at Children’s Hospital Los Angeles and the University of Southern California have developed the first fully implantable micropacemaker designed for use in a fetus with complete heart block. The investigators anticipate the first human use of the device in the near future.
Most children with HIV who have low levels of a key immune cell eventually recover levels of this cell after they begin treatment.
The program for the upcoming health-care symposium is being finalized, featuring more than 200 presentations by researchers, physicians and other health-care providers, medical device designers, policy-makers, health IT professionals, and biomedical engineers.
Researchers have found a powerful relationship between prenatal polycyclic aromatic hydrocarbon (PAH) exposure and disturbances in parts of the brain that support information processing and behavioral control.
It’s been nearly a decade since Gheorghe Sandru received the heart implant that changed his life. Sandru, 85, was the first patient enrolled in a Cedars-Sinai clinical trial for a tiny implant known as the WATCHMAN Device. It reduces the risk of deadly strokes in patients with erratic heartbeats by closing a pouch in the heart where blood pools, preventing clots from traveling out of the heart and into the body. Now it’s his wife’s turn.
Men who exercise more have better erectile and sexual function, regardless of race, according to a recent study published in the Journal of Sexual Medicine.
Investigators have demonstrated that MR imaging of the liver is more accurate than liver biopsy in determining total body iron balance in patients with sickle cell disease and other disorders requiring blood transfusion therapy. This discovery follows the researchers earlier work in pioneering techniques to use MRI to noninvasively measure liver iron.
UCLA professor argues that insuring undocumented Latinos under the Affordable Care Act would, in the long run, be less expensive and provide better care.
Results of a new study by UCLA researchers has found that a groundbreaking new triple combination therapy shows promising signs of more effectively controlling advanced melanoma than previous BRAF + MEK inhibitor or BRAF inhibitor + immunotherapy combos alone, and with increased immune response and fewer side effects.
By uncovering the mechanism by which fibrous tissue cells in the lung multiply, researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA), along with colleagues in Mexico and Canada, have identified a promising new approach for the treatment of pulmonary fibrosis.
When a person has cancer that spreads to the bone and bone marrow, the tissue becomes increasingly fragile, often leading to increased bone resorption. In a surprising discovery, investigators at Children’s Hospital Los Angeles reported that when neuroblastoma (NB) cells metastasize to the bone, there initially occurs an increase in bone deposition, not resorption. This process is driven by a chemical messenger called VEGFA.
Could push-ups and hula hoops put students on the path to becoming brain-health scientists? About 140 seventh- and eighth-graders attending Cedars-Sinai’s Brainworks program March 23 will learn how hopping, skipping, jumping and other elements of a regular exercise routine may help improve brain health. An exercise station – a new feature of the 17-year-old program – will be one of nine areas where students will interact with Cedars-Sinai neurosurgeons, neurologists, neuroscientists and other health professionals.
As the new chair of the American College of Healthcare Executives, Richard D. Cordova urges his peers to adapt and lead through heath care industry change.
Two Cedars-Sinai Heart Institute physician-researchers are to receive prestigious awards from the American College of Cardiology during the medical society’s 64th Annual Scientific Session & Expo.
UCLA researchers have for the first time described cost across an entire care process for a common condition called benign prostate hyperplasia (BPH) using time-driven activity-based costing. They found a 400 percent discrepancy between the least and most expensive ways to treat the condition.
Philanthropists Gene P. and Mindy Stein, through the Tikun Olam Foundation, have made a $1 million gift to establish the Stein Tikun Olam Infant-Family Mental Health Initiative at Children’s Hospital Los Angeles (CHLA).
UCLA Health System and the Sound Body Sound Mind Foundation have formed a partnership to provide practical ways to combat childhood obesity and promote healthy lifestyles in Los Angeles.
Twenty California journalists are gathering this week for the USC Annenberg California Health Journalism Fellowship.
The benefits of weight loss surgery, along with a treatment plan that includes exercise and dietary changes, are well documented. In addition to a significant decrease in body mass, many patients find their risk factors for heart disease are drastically lowered and blood sugar regulation is improved for those with Type 2 diabetes. Some patients, however, do not experience the optimal weight loss from bariatric surgery. The presence of a specific methane gas-producing organism in the gastrointestinal tract may account for a decrease in optimal weight loss, according to new research by Ruchi Mathur, MD, at Cedars-Sinai.
Drivers have been slow to adopt electric vehicles due to “range anxiety,” the fear of becoming stranded with an empty battery. This phenomenon was recently addressed in a study that aims to explain range anxiety and determine whether hands-on experience can reduce drivers’ stress.
Commentary provides evidence that the degree of income inequality can lead to a long list of health issues.
An on-board air filtration system developed specifically for school buses reduces exposure to vehicular pollutants by up to 88 percent, according to a study by researchers at the UCLA Fielding School of Public Health.
Don Moir, an ALS patient, wrote a love letter to his wife and was able to audibly say “I love you, Lorraine” for the first time in 15 years, thanks to a digital solution by the Not Impossible team, Speak Your Mind Foundation and HP’s #BendTheRules.
PTSD. Four letters we immediately associate with soldiers and horrific wartime tragedies. But unfortunately, posttraumatic stress disorder (PTSD) can affect anyone who has experienced a traumatic event—including children with serious medical diagnoses. To learn more about this devastating disorder in kids, we talked to Jeffrey I. Gold, PhD, director of the Pediatric Pain Management Clinic at Children’s Hospital Los Angeles (CHLA).
UCLA researchers have found that radiation therapy is the most common treatment for men with prostate cancer regardless of the aggressiveness of the tumor, risk to the patient and overall patient prognosis. These findings lay the groundwork for improved treatment assessment by physicians and to better inform men fighting the disease.
Children’s Hospital Los Angeles announced today that it will make an institutional commitment of $50 million to expand its Center for Personalized Medicine. This investment in leading-edge research and innovation will help unlock the human genome’s potential with the goal of making diagnoses more effective, therapies more targeted and health care more personalized for children. The Children’s Hospital Los Angeles Board of Trustees recently approved the investment in the Center, to be disbursed over the next five years. The institution will seek an additional $50 million in philanthropic funding from the community to support the translation of research outcomes in the lab into bedside care for infants, children and adolescents.
Two of the nation’s top eye institutes have united in an affiliation that will improve patients’ access to leading vision specialists.
Latinos are one of the fastest growing ethnic groups in the United States, with their numbers having risen 243 percent since 1980. Yet the number of Latino physicians per 100,000 Latinos has declined by 22 percent during that period.
Miami Herald reporters Carol Marbin Miller and Audra D.S. Burch have won USC Annenberg’s 2015 Selden Ring Award for Investigative Reporting, for their examination of six years of child deaths in Florida.
Prominent entrepreneur Ming Hsieh and his wife Eva have made a $1 million gift to support the Children’s Orthopaedic Center at Children’s Hospital Los Angeles (CHLA).
Research shows that by promoting relationships this Valentine's Day, companies may be conveying they “love you not...”
In the first study of its kind, a consortium led by UCLA physicians found that paramedics can start medications for patients in the first minutes after onset of a stroke. While the specific drug tested, magnesium sulfate, did not improve patient outcomes, the research has resulted in a new method to get promising treatments to stroke patients quickly.
FDA has approved IBRANCE (palbociclib), representing a new treatment method to arrest tumor growth in certain advanced breast cancer patients. IBRANCE targets a key family of proteins responsible for cell growth. Results of a phase 2 study found the combination of IBRANCE and letrozole improved progression-free survival by 10 months as compared to letrozole alone. Over 80 percent of metastatic ER+ breast cancer patients received some benefit from this treatment.
Two scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received a California Institute of Regenerative Medicine (CIRM) Tools and Technology Award that will forward revolutionary stem cell medicine. The UCLA researchers were among only 20 scientists nationwide to receive the Tools and Technologies Award, the most of any institution represented.
A pioneering surgery may help people suffering from a frustrating breathing condition in which the damaged phrenic nerve prevents the diaphragm from getting the message to breathe.
February is American Heart Month. UCLA cardiologists from the UCLA Barbra Streisand Women’s Heart Health Program offer heart healthy tips.
Richard Kim, MD, a cardiac surgeon at Children’s Hospital Los Angeles, recently used a 3D printed heart as a model to plan a life-saving procedure for his young patient, Esther Perez.
Researchers in the Cedars-Sinai Board of Governors Regenerative Medicine Institute have devised a novel way to generate transplantable corneal stem cells that may eventually benefit patients suffering from life-altering forms of blindness.
Researchers at Children's Hospital Los Angeles demonstrated the efficacy and safety of a new fusion protein in mouse models of aggressive human leukemia using leukemia cells taken directly from patients with ALL.
Deepa Bhojwani, MD, joins Children’s Hospital Los Angeles (CHLA) as director of the Leukemia/Lymphoma program within the Children’s Center for Cancer and Blood Diseases on February 15, 2015.
January tip sheet of patient features and human interest story ideas from Cedars-Sinai. All of these patients have been -- or are being -- treated for brain-related disorders -- malignant and benign brain tumors, arteriovenous malformations, and essential tremor, etc. From a former professional singer to a young mother of three, to a retired church pastor, all have compelling stories to tell and are available for interviews along with their physicians. A detailed backgrounder is available for each individual highlighted.
A new study finds that the factors influencing children’s readiness for kindergarten include not only whether they attend preschool, but also their families’ behaviors, attitudes and values — and that parents’ expectations go a long way toward predicting children’s success throughout their schooling.
Researchers have shown that neonatal mouse hearts have varying regenerative capacities depending upon the severity of injury. Approaches to extend this regenerative capacity in a mammalian model, from the neonatal period to the juvenile or adult period, could help identify new treatment options for humans.
UCLA researchers have treated mice that mimic human autism with a neuropeptide called oxytocin, and have found that it restores normal social behavior. In addition, the findings suggest that giving oxytocin as early as possible in the animal’s life leads to more lasting effects in adults and adolescents.
Center for Advancement of Science in Space (CASIS) awarded grant funding to UCLA for stem cell researchers to send rodents into space to test new therapy for prevention of bone loss. Research has enormous translational potential for astronauts in space flight and patients on Earth with osteoporosis or other bone loss problems from disease, illness or trauma.
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