In a clinical trial of the immunotherapy drug pembrolizumab, half of 25 patients with a rare type of virus-linked skin cancer called Merkel cell carcinoma experienced substantial tumor shrinkage lasting nearly three times as long, on average, than with conventional chemotherapy.
A team of researchers led by Ludwig Cancer Research scientist Stephen Hodi reported today the results of the longest follow-up survival study conducted to date on patients with advanced melanoma who were treated with the PD-1 inhibitor nivolumab. Hodi and his colleagues announced at a press event during the American Association for Cancer Research Annual Meeting in New Orleans that 34 percent of the patients treated with this immunotherapy alone in a previous Phase 1 trial were still alive five years later.
More than 18,500 people from 107 countries attended the American Academy of Dermatology’s 74th Annual Meeting, which ran from March 4-8 at the Walter E. Washington Convention Center in Washington.
Board-certified dermatologist Suzanne Olbricht, MD, FAAD, is named president-elect of the American Academy of Dermatology (Academy), the world’s largest dermatologic society, which represents more than 18,000 physicians who specialize in the diagnosis and treatment of skin, hair and nail conditions.
The American Academy of Dermatology (Academy) has announced the results of its annual election.
Ever wonder what causes corns and calluses? According to dermatologists from the American Academy of Dermatology, these hard, thickened areas of skin form as a result of friction or pressure on the skin. In fact, they say, corns and calluses develop naturally to help protect the skin underneath them.
Researchers at Massachusetts General Hospital (MGH) have identified a type of immune cell that appears to block the progress of melanoma and other cancers in animal models. These subcapsular sinus (SCS) macrophages form a protective coating around lymph nodes, preventing the entry of tiny structures that transport bits of tumor tissue and help the cancer to grow and spread. However, the SCS macrophage barrier appears to be temporary, as it breaks down as the tumor progresses and in response to some cancer treatment drugs.
An international team of scientists led by The Wistar Institute have shown that aged tumor cells in melanoma behave differently than younger tumor cells, according to study results published in the journal Nature. Changes in the microenvironment make these older tumor cells more metastatic and more resistant to treatment with targeted therapies.
New research looks into the paradox that women who sunbathe are likely to live longer than those who avoid the sun, even though sunbathers are at an increased risk of developing skin cancer.
In December 2015, the FDA proposed new restrictions related to tanning bed use, including banning their use among individuals younger than 18. As the comment period on the proposal winds down, a Rutgers Cancer Institute of New Jersey investigator who conducts research on tanning behaviors weighs in.
It may be tempting to squeeze or pop a painful lump on your skin, but experts advise against it. The bump could be a boil – a pus-filled skin infection that occurs around a hair follicle or oil gland – or a stye if the lump is on your eyelid. According to dermatologists, squeezing a boil or stye could make the infection worse.
Clinicians and researchers from the George Washington University Department of Dermatology will present on a variety of topics including Nanotechnology, Atopic and Contact Dermatitis, Wound Healing, and Psoriasis at the 74th Annual Meeting of the American Academy of Dermatology, March 4 – 8 in Washington, D.C.
Not all dermatology websites and apps offer the same standard of care. Fortunately, there are steps patients can take to evaluate teledermatology services, allowing them to receive the best possible care while enjoying the benefits of a remote consultation.
In certain cases, genetic and molecular testing can yield valuable information that helps dermatologists provide individualized care for their melanoma patients.
According to new research presented at the American Academy of Dermatology’s 74th Annual Meeting in Washington, acne patients are often perceived negatively by others, which may affect patients’ quality of life.
While pregnant women with chronic skin conditions may fear that treating these conditions could compromise their baby’s health, a board-certified dermatologist can develop safe and effective treatment plans for these patients.
From removing birthmarks to reducing wrinkles, dermatologists can use laser treatments to help patients in more ways than ever. Thanks to recent advances in laser technology, experienced practitioners can offer more effective treatments with less downtime for patients.
African-American women are prone to hair loss, and new data illustrates the scope of this problem, which often goes undiagnosed. Women who are concerned about losing their hair should consider changing their styling practices and see a dermatologist if they notice any signs of hair loss.
Published online in the Journal of the American Academy of Dermatology on Feb. 17, the American Academy of Dermatology’s new “Guidelines of care for the management of acne vulgaris" cover acne treatment recommendations for both adolescents and adults.
Winter's arctic blast can wreak havoc on delicate skin. Nicole Burkemper, M.D., associate professor of dermatology at Saint Louis University, shares her tips for updating your skin regimen for the season.
For the first time researchers have developed a process for altering the ingredients in a sunscreen that does not impact its sun protection factor (SPF), but does allow the body to produce vitamin D. The findings, published in the peer reviewed journal PLOS ONE, has led to the production of a new sunscreen called Solar D.
A web-based intervention targeted toward young, female users of indoor tanning beds has tested favorably among these users and may encourage cessation of this behavior. That is according to research by Rutgers Cancer Institute which tested an intervention that targeted users’ perceptions of the benefits and value of tanning
At least 60 genetic diseases called neurocutaneous disorders involve the skin, central nervous system, and/or peripheral nervous system, Loyola University Medical Center neurologists report.
According to board-certified dermatologists from the American Academy of Dermatology, nickel is one of the most common causes of allergic contact dermatitis: a skin rash or irritation caused by touching an allergen. In fact, it is estimated that more than 18 percent of people in North America are allergic to nickel, including 11 million children in the U.S.
When the temperature dips below freezing, it’s critical to protect your skin from cold-weather health risks. Stay warm and prevent frostbite by following these tips from dermatologists.
A new study shows that a blood test which monitors blood levels of DNA fragments from dead cancer cells does a better job than the current standard test at tracking the severity and potential spread of metastatic melanoma. The study, by researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center, is set for publication tomorrow in the January edition of Molecular Oncology.
By utilizing a revolutionary method that allows mice to serve as “avatars” for patients, scientists at The Wistar Institute have shown that a previously ineffective targeted drug for melanoma may actually be quite potent in halting the progression of disease in certain patients.
A first-of-its-kind (anti-PD-1) immunotherapy was approved today by the U.S. Food & Drug Administration as first-line treatment for metastatic melanoma—allowing greater access to this therapy for patients without having to previously receive other prior treatments.
The American Academy of Dermatology applauds the U.S. Food and Drug Administration for taking a monumental step to protect the public’s health by proposing new regulations governing indoor tanning.
The American Academy of Dermatology Association (AADA) announced its support for the Medicare Advantage Bill of Rights Act, introduced today by Sen. Sherrod Brown (D-Oh.) and Rep. Rosa DeLauro (D-Conn.). If passed, the legislation would ensure that patients will have adequate physician networks in their Medicare Advantage plans.
Using olive or sunflower oil on new born babies’ skin damages the barrier which prevents water loss and blocks allergens and infections, new research led by The University of Manchester has found.
Dietary fucose supplementation found to suppress the growth of melanoma
In the first known study to examine the prevalence and treatment of psoriasis in older Americans, experts from the Perelman School of Medicine at the University of Pennsylvania have found that black patients receiving Medicare are less likely to receive biologic therapies –medications derived from human or animal cells or tissues – for the treatment of moderate to severe psoriasis than white patients.
This month, the American Academy of Dermatology released its Chronic Hives Patient App, which offers tools and resources for chronic hives management.
Don’t believe the hype when you see those creams and ointments promising to prevent or reduce pregnancy stretch marks. Dermatologists are still learning about what causes stretch marks in the first place, and for this new study U-M researchers investigate causes at the molecular level.
Technion scientists have developed a self-healing, flexible sensor that mimics the self-healing properties of human skin. Incidental scratches or cuts to the sensors "heal" themselves in less than one day.
A common ingredient in sunscreen could be an effective antibacterial coating for medical implants such as pacemakers and replacement joints.
FDA today approved a new therapy that combines vemurafenib (Zelboraf), a drug used to treat melanoma, with cobimetinib (Cotellic). Study conducted at UCLA and other sites internationally showed significantly improved response rates to the therapy in men and women with advanced melanoma with a BRAF mutation.
November is National Healthy Skin Month, and member dermatologists from the American Academy of Dermatology want to set one thing straight: you don’t need expensive skin care products to have glowing, healthy skin. In fact, they say, wearing a broad-spectrum, water-resistant sunscreen with an SPF of 30 or higher before going outdoors is one of the most effective ways to maintain healthy skin.
Trial to confirm safety and efficacy of new drug for rare disease.
A common heart drug may stop the progression of angiosarcoma, a cancer of the inner lining of blood vessels, according to a study by researchers at Texas Tech University Health Sciences Center (TTUHSC) El Paso.
A medical records analysis by researchers at NYU Langone Medical Center concludes that physicians who treat severe acne leave too many patients on ineffective antibiotics for far too long before prescribing more potent needed therapy with the medication isotretinoin, sometimes known by its former brand name Accutane.
The U.S. Food and Drug Administration announced on Oct. 27 that it has approved, for the first time, an oncolytic (cancer-killing) viral therapy in the United States. The drug was approved for use against late-stage melanoma, a deadly skin cancer.
• Prof. Yardena Samuels and her team at the Weizmann Institute of Science have found a tumor suppressor gene, RASA2, that drives a particularly deadly form of melanoma as well as regulates a key protein, RAS, that is a major oncogene. The discovery is “highly likely to have direct clinical relevance.”
Inhibiting a family of enzymes inside hair follicles that are suspended in a resting state restores hair growth, a new study from researchers at Columbia University Medical Center has found.
A new application for the Apple iPhone enables users to measure and track their moles by comparing their potential trouble spots over time. The ‘Mole Mapper’ app analyzes digital photos of moles and other skin conditions that users take with their cell phones. Scientists who study melanoma use the de-identified data from users to complement other research efforts.
Warts aren’t just for witches and goblins. According to member dermatologists from the American Academy of Dermatology, children and teens, people who frequently bite their nails, and people with a weakened immune system are more prone to getting warts than others.
Gay and bisexual men were up to six times more likely than heterosexual men to take part in indoor tanning, and twice as likely to report a history of skin cancer, including nonmelanoma and melanoma, according to a study led by UC San Francisco researchers.
Online advertising based on Google search terms is a potentially effective way to deliver targeted cancer prevention education, according to a study led by Eleni Linos, MD, DrPH, an assistant professor of dermatology at UC San Francisco.
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