Curated News: PLOS

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Released: 3-Sep-2015 4:05 PM EDT
Rapid Testing for TB Aims to Reduce Drug Resistance, Lower Mortality Rate
UC San Diego Health

Researchers at University of California, San Diego School of Medicine have documented the accuracies of three new tests for more rapidly diagnosing drug-resistant forms of tuberculosis (TB), which are much harder and more expensive to treat and which, experts say, represent a major threat to global public health.

Released: 31-Aug-2015 2:00 PM EDT
Gene Leads to Nearsightedness When Kids Read
Columbia University Irving Medical Center

Vision researchers at Columbia University Medical Center have discovered a gene that causes myopia, but only in people who spend a lot of time in childhood reading or doing other “nearwork.”

Released: 31-Aug-2015 1:05 PM EDT
Time-Lapse Analysis Offers New Look at How Cells Repair DNA Damage
Lawrence Berkeley National Laboratory

Time-lapse imaging can make complicated processes easier to grasp. Berkeley Lab scientists are using a similar approach to study how cells repair DNA damage. Microscopy images are acquired about every thirty minutes over a span of up to two days, and the resulting sequence of images shows ever-changing hotspots inside cells where DNA is under repair.

26-Aug-2015 4:15 PM EDT
Study: Better Signs Could Help Reduce Friction Between Motorists, Bicyclists
North Carolina State University

Web-based survey finds "Bicyclists May Use Full Lane," more effective message for signs

Released: 27-Aug-2015 5:05 PM EDT
An Ounce of Prevention: Research Advances on ‘Scourge’ of Transplant Wards
University of Wisconsin–Madison

The fungus Cryptococcus causes meningitis, a brain disease that kills about 1 million people each year. It’s difficult to treat because fungi are genetically quite similar to humans, so compounds that affect fungi tend to have toxic side effects for patients. Now, researchers at the University of Wisconsin-Madison have identified 18 proteins that play a role in spore formation and germination. The findings raises the possibility of preventing the disease by blocking the spores’ germination.

24-Aug-2015 10:05 AM EDT
Less May Be More in Slowing Cholera Epidemics
Johns Hopkins Bloomberg School of Public Health

An oral cholera vaccine that is in short supply could treat more people and save more lives in crisis situations, if one dose were dispensed instead of the recommended two, new Johns Hopkins Bloomberg School of Public Health research suggests.

21-Aug-2015 2:00 PM EDT
Worming Our Way to a New Understanding of Behaviour
MRC Clinical Sciences Centre/Institute of Clinical Sciences (ICS) Faculty of Medicine, Imperial College London

The wriggling and writhing of worms may hold clues to the inner workings of our brains, according to scientists at the MRC’s Clinical Sciences Centre at Imperial College London. The researchers have developed a pioneering tool to analyse a worm’s posture as it wriggles, and will use the tool to investigate how exactly the worm’s brain controls its movements.

Released: 20-Aug-2015 2:00 PM EDT
Saint Louis University Researchers Suggest Approach to Fight Common Virus in Immunosuppressed Patients
Saint Louis University Medical Center

Findings by Saint Louis University researchers shed light on how adenovirus replicates in humans. The findings suggest that agents that enhance the Type I interferon signaling pathway could be useful to fight adenovirus infections in immunosuppressed patients.

19-Aug-2015 1:05 PM EDT
When Personal Identity Really Matters
University of California, San Francisco (UCSF)

A study led by researchers at UCSF has found that when that when self-identification matters most – in connecting bone marrow donors to patients – the format of the questions may determine how well the answers actually correspond to their genes.

19-Aug-2015 1:05 PM EDT
When Personal Identity Really Matters
University of California, San Francisco (UCSF)

A study led by researchers at UCSF has found that when that when self-identification matters most – in connecting bone marrow donors to patients – the format of the questions may determine how well the answers actually correspond to their genes.

17-Aug-2015 2:00 PM EDT
Hot Chilli May Unlock a New Treatment for Obesity
University of Adelaide

University of Adelaide researchers have discovered a high-fat diet may impair important receptors located in the stomach that signal fullness.

17-Aug-2015 2:00 PM EDT
Hot Chilli May Unlock a New Treatment for Obesity
University of Adelaide

University of Adelaide researchers have discovered a high-fat diet may impair important receptors located in the stomach that signal fullness.

Released: 14-Aug-2015 6:05 PM EDT
What’s Lurking in Your Lungs? Surprising Findings Emerge From U-M Microbiome Research
Michigan Medicine - University of Michigan

With every breath you take, microbes have a chance of making it into your lungs. But what happens when they get there? And why do dangerous lung infections like pneumonia happen in some people, but not others? Researchers have started to answer these questions by studying the microbiome of the lungs.

   
11-Aug-2015 8:00 AM EDT
A Better Way to Personalize Bladder Cancer Treatments
UC Davis Health

Researchers at UC Davis, in collaboration with colleagues at Jackson Laboratory, have developed a new way to personalize treatments for aggressive bladder cancer. In early proof-of-concept research, the team took bladder tumors from individual patients, identified actionable mutations and grafted the tumors into mice. From there, the researchers simultaneously tested multiple therapies in the tumor models. Treatments that were effective in the models could then be given to patients. The research was published today in the journal PLOS One.

11-Aug-2015 8:00 AM EDT
A Better Way to Personalize Bladder Cancer Treatments
UC Davis Health

Researchers at UC Davis, in collaboration with colleagues at Jackson Laboratory, have developed a new way to personalize treatments for aggressive bladder cancer. In early proof-of-concept research, the team took bladder tumors from individual patients, identified actionable mutations and grafted the tumors into mice. From there, the researchers simultaneously tested multiple therapies in the tumor models. Treatments that were effective in the models could then be given to patients. The research was published today in the journal PLOS One.

Released: 13-Aug-2015 4:05 AM EDT
Big Data and the Social Character of Genes
University of Haifa

In a new study, researchers managed to narrow down 900 million possibilities requiring examination of the connection between genetic markers and genetic expression to just 340,000, in the process identifying “social” genes that play a cooperative role

Released: 13-Aug-2015 4:05 AM EDT
Big Data and the Social Character of Genes
University of Haifa

In a new study, researchers managed to narrow down 900 million possibilities requiring examination of the connection between genetic markers and genetic expression to just 340,000, in the process identifying “social” genes that play a cooperative role

7-Aug-2015 8:30 AM EDT
Could Flu Someday Be Prevented Without a Vaccine?
Ohio State University

Researchers have discovered a way to trigger a preventive response to a flu infection without any help from the usual players – the virus itself or interferon, a powerful infection fighter. The finding suggests that manipulating a natural process could someday be an alternative way to not just reduce flu severity, but prevent infection.

Released: 6-Aug-2015 2:05 PM EDT
High Blood Sugar of Diabetes Can Cause Immune System Malfunction, Triggering Infection
Case Western Reserve University

Case Western Reserve scientists may have uncovered a mechanism that sets into motion dangerous infection occurring with uncontrolled diabetes. High blood sugar appears to unleash molecules that interfere with the body’s infection-control defenses. These findings appear in this week in PLOS ONE.

Released: 6-Aug-2015 2:05 PM EDT
High Blood Sugar of Diabetes Can Cause Immune System Malfunction, Triggering Infection
Case Western Reserve University

Case Western Reserve scientists may have uncovered a mechanism that sets into motion dangerous infection occurring with uncontrolled diabetes. High blood sugar appears to unleash molecules that interfere with the body’s infection-control defenses. These findings appear in this week in PLOS ONE.

Released: 6-Aug-2015 10:05 AM EDT
A Powerful Molecular Promoter of Colon Cancers
Perelman School of Medicine at the University of Pennsylvania

Cancer researchers already know of some oncogenes and other factors that promote the development of colon cancers, but they don’t yet have the full picture of how these cancers originate and spread. Now researchers have illuminated another powerful factor in this process, by unraveling an additional pathway for the origin of colon cancer.

Released: 5-Aug-2015 4:05 PM EDT
Making a Better Nitrate Test Kit
Michigan Technological University

This little black box could change how we study one of the world's biggest water quality issues. Our Michigan Tech team joined up with the Nitrate Elimination Company to create this this new nitrate test kit.

Released: 5-Aug-2015 4:05 PM EDT
Making a Better Nitrate Test Kit
Michigan Technological University

This little black box could change how we study one of the world's biggest water quality issues. Our Michigan Tech team joined up with the Nitrate Elimination Company to create this this new nitrate test kit.

3-Aug-2015 9:00 AM EDT
Surveys Reveal Trends in Global Consumption of Sugary Beverages, Fruit Juices and Milk
Tufts University

A team led by researchers from the Friedman School of Nutrition Science and Policy at Tufts University estimated global intakes of sugar-sweetened beverages, fruit juices, and milk across 187 countries. Variation was identified by age, sex and region, with implications for national and global nutrition policies.

Released: 4-Aug-2015 9:40 AM EDT
Trachoma Risk Tied to Sleeping Near Cooking Fires, Lack of Ventilation
NIH, National Eye Institute (NEI)

Children who sleep in unventilated rooms with cooking fires are at greater risk for severe trachoma, a leading cause of preventable blindness in developing countries, according to the findings of a recent study conducted in Tanzania. The study was supported by the National Eye Institute, part of the National Institutes of Health.

Released: 4-Aug-2015 8:45 AM EDT
GBSI’s #Authenticate Campaign Tops 100 Supporters as Susan G. Komen® Champions Cause
Global Biological Standards Institute (GBSI)

Global Biological Standards Institute (GBSI) announced today that Susan G. Komen has signed on as Champion of its #authenticate campaign, bringing the total to more than 100 official supporters of the initiative. The campaign, launched in April 2015, seeks to expand cell line authentication in biomedical research in order to decrease the use of misidentified and contaminated cell lines and ultimately advance cures. GBSI is encouraging widespread adoption of cell authentication.

Released: 29-Jul-2015 2:05 PM EDT
Researchers Illuminate Key Role of NOX Proteins in Liver Disease
UC San Diego Health

Researchers at the University of California, San Diego School of Medicine have demonstrated a direct connection between two signaling proteins and liver fibrosis, a scarring process underlying chronic liver disease, the 12th leading cause of death in the United States.

Released: 29-Jul-2015 2:05 PM EDT
Researchers Illuminate Key Role of NOX Proteins in Liver Disease
UC San Diego Health

Researchers at the University of California, San Diego School of Medicine have demonstrated a direct connection between two signaling proteins and liver fibrosis, a scarring process underlying chronic liver disease, the 12th leading cause of death in the United States.

28-Jul-2015 3:50 PM EDT
Proof-of-Concept Study Shows Successful Transport of Blood Samples with Small Drones
Johns Hopkins Medicine

In a proof-of-concept study at Johns Hopkins, researchers have shown that results of common and routine blood tests are not affected by up to 40 minutes of travel on hobby-sized drones.

28-Jul-2015 4:55 PM EDT
Small Study Affirms Accuracy of Free Mobile App That Screens for Liver Disease in Newborns
Johns Hopkins Medicine

In a small study, researchers from the Johns Hopkins Children’s Center report they have verified the ability of a free smartphone app to accurately read, interpret and record the color of a newborn’s poop as a possible early symptom of biliary atresia (BA) — a rare disorder that accounts for nearly half of pediatric end-stage liver disease in the United States.

Released: 29-Jul-2015 11:05 AM EDT
Citrus Greening Bacterium Changes the Behavior of Bugs to Promote Its Own Spread
University of Florida Institute of Food and Agricultural Sciences

The disease that threatens to destroy Florida’s $10.7 billion citrus industry appears to have its own mechanism to promote its spread, making it harder to control.

Released: 29-Jul-2015 11:05 AM EDT
Citrus Greening Bacterium Changes the Behavior of Bugs to Promote Its Own Spread
University of Florida Institute of Food and Agricultural Sciences

The disease that threatens to destroy Florida’s $10.7 billion citrus industry appears to have its own mechanism to promote its spread, making it harder to control.

Released: 27-Jul-2015 9:00 AM EDT
Study May Show a Way to Predict Whether Children with a Genetic Disorder Will Develop Autism or Psychosis
University of California, Los Angeles (UCLA), Health Sciences

Findings are the first to shed light on the genetic differences between DiGeorge syndrome patients with autism and those with psychosis.

Released: 23-Jul-2015 4:05 PM EDT
American poverty prospects higher than expected
Washington University in St. Louis

For Americans, the likelihood of experiencing relative poverty at least once in their lifetime is surprisingly high, finds a new analysis from noted poverty expert Mark Rank, PhD, professor at the Brown School at Washington University in St. Louis.

21-Jul-2015 7:25 AM EDT
Researchers Discover Simple Solution to Worrying Levels of Arsenic in Our Rice
Queen's University Belfast

New research from Queen's University Belfast, UK, shows that cooking rice with a percolation-based system removes up to 85% of inorganic arsenic, a known carcinogen

21-Jul-2015 7:25 AM EDT
Researchers Discover Simple Solution to Worrying Levels of Arsenic in Our Rice
Queen's University Belfast

New research from Queen's University Belfast, UK, shows that cooking rice with a percolation-based system removes up to 85% of inorganic arsenic, a known carcinogen

Released: 16-Jul-2015 2:05 PM EDT
Burden of Dengue, Chikungunya in India Far Worse Than Understood
Johns Hopkins Bloomberg School of Public Health

New Johns Hopkins Bloomberg School of Public Health research finds new evidence that an extremely high number of people in southern India are exposed to two mosquito-borne viruses -- dengue and chikungunya.

10-Jul-2015 12:00 PM EDT
Brain-Based Algorithms Make for Better Networks
Salk Institute for Biological Studies

Salk and Carnegie Mellon researchers uncover how the brain prunes back synapses in development

Released: 16-Jul-2015 12:05 PM EDT
Climate Change Just One of Many Risks to Trees in the Tropical Andes
Bournemouth University

Bournemouth University experts have analysed the potential impact of changing climate conditions on the tree species that occur in the tropical Andes, along with other factors.

Released: 15-Jul-2015 2:05 PM EDT
Hydraulic Fracturing Linked to Increases in Hospitalization Rates in the Marcellus Shale Region
Perelman School of Medicine at the University of Pennsylvania

Hospitalizations for heart conditions, neurological illness, and other conditions were higher among people who live near unconventional gas and oil drilling (hydraulic fracturing), according to new research.

Released: 15-Jul-2015 2:05 PM EDT
Hydraulic Fracturing Linked to Increases in Hospitalization Rates in the Marcellus Shale Region
Perelman School of Medicine at the University of Pennsylvania

Hospitalizations for heart conditions, neurological illness, and other conditions were higher among people who live near unconventional gas and oil drilling (hydraulic fracturing), according to new research.

Released: 15-Jul-2015 12:05 PM EDT
Study Finds Southeast’s Rural Landscapes Pose Potential Risk for Salmonella Infection
University of Georgia

Researchers from the University of Georgia have determined that various freshwater sources in Georgia, such as rivers and lakes, could feature levels of salmonella that pose a risk to humans. The study is featured in the July edition of PLOS One.

30-Jun-2015 1:05 PM EDT
Targeting Bacteria in the Gut MightHelp Burn and Trauma Patients
Loyola Medicine

A PLOS ONE study has found that burn patients experience dramatic changes in the 100 trillion bacteria inside the gastrointestinal tract.There was an increase in potentially harmful bacteria, and decrease in beneficial bacteria. The findings suggest that burn patients might benefit from treatment with probiotics.

30-Jun-2015 1:05 PM EDT
Targeting Bacteria in the Gut MightHelp Burn and Trauma Patients
Loyola Medicine

A PLOS ONE study has found that burn patients experience dramatic changes in the 100 trillion bacteria inside the gastrointestinal tract.There was an increase in potentially harmful bacteria, and decrease in beneficial bacteria. The findings suggest that burn patients might benefit from treatment with probiotics.

6-Jul-2015 8:05 AM EDT
Remediating Abandoned, Inner City Buildings Reduces Crime and Violence in Surrounding Areas
Perelman School of Medicine at the University of Pennsylvania

Fixing up abandoned buildings in the inner city doesn’t just eliminate eyesores, it can also significantly reduce crime and violence, including gun assaults, researchers from the University of Pennsylvania and Penn’s Perelman School of Medicine report in the first study to demonstrate the direct impact of building remediation efforts on crime.

6-Jul-2015 8:05 AM EDT
Remediating Abandoned, Inner City Buildings Reduces Crime and Violence in Surrounding Areas
Perelman School of Medicine at the University of Pennsylvania

Fixing up abandoned buildings in the inner city doesn’t just eliminate eyesores, it can also significantly reduce crime and violence, including gun assaults, researchers from the University of Pennsylvania and Penn’s Perelman School of Medicine report in the first study to demonstrate the direct impact of building remediation efforts on crime.

6-Jul-2015 9:10 AM EDT
Study Estimates Number of Deaths Attributed to Low Levels of Education
New York University

A new study by researchers at the University of Colorado, New York University, and the University of North Carolina at Chapel Hill estimates the number of deaths that can be linked to differences in education, and finds that variation in the risk of death across education levels has widened considerably.

6-Jul-2015 9:10 AM EDT
Study Estimates Number of Deaths Attributed to Low Levels of Education
New York University

A new study by researchers at the University of Colorado, New York University, and the University of North Carolina at Chapel Hill estimates the number of deaths that can be linked to differences in education, and finds that variation in the risk of death across education levels has widened considerably.

Released: 8-Jul-2015 11:30 AM EDT
Patent Filings by Women Have Risen the Fastest in Academia
Indiana University

The number of women across the globe filing patents with the U.S. Patent and Trade Office over the past 40 years has risen fastest within academia compared to all other sectors of the innovation economy, according to a new study from Indiana University.

Released: 8-Jul-2015 11:30 AM EDT
Patent Filings by Women Have Risen the Fastest in Academia
Indiana University

The number of women across the globe filing patents with the U.S. Patent and Trade Office over the past 40 years has risen fastest within academia compared to all other sectors of the innovation economy, according to a new study from Indiana University.



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