Curated News: JAMA

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8-Aug-2017 12:45 PM EDT
Out-of-Pocket Costs Exceed What Many Insured Cancer Patients Expect to Pay
Duke Health

A third of insured people with cancer end up paying more out-of-pocket than they expected, despite having health coverage, researchers at the Duke Cancer Institute have found.

Released: 9-Aug-2017 1:30 PM EDT
Researchers Look to Improve Detection of Skin Cancer Lacking Pigment Melanin
University of North Carolina Health Care System

UNC Lineberger scientists led a multi-institution research team to identify key features linked to amelanotic melanoma, a form of skin cancer that lacks the brown or black color that stems from the pigment melanin.

Released: 7-Aug-2017 8:00 AM EDT
Netflix Drama “13 Reasons Why” Linked to Suicidal Thoughts
San Diego State University

A recent study out of San Diego State University has found an increase of internet searches for suicide immediately following the release of the popular Netflix show “13 Reasons Why.” Researchers used data from Google Trends and found that suicide-related queries were 19 percent higher than expected following the show’s release in March.

1-Aug-2017 8:00 AM EDT
Study Adds to Evidence That Most Prescribed Opioid Pills Go Unused
Johns Hopkins Medicine

In a review of half a dozen published studies in which patients self-reported use of opioids prescribed to them after surgery, researchers at Johns Hopkins report that a substantial majority of patients used only some or none of the pills, and more than 90 percent failed to dispose of the leftovers in recommended ways.

25-Jul-2017 11:30 AM EDT
Genetic Testing Helps Detect Cause of Early Life Epilepsy
Ann and Robert H. Lurie Children's Hospital of Chicago

A study published in JAMA Pediatrics supports the use of genetic testing, especially with sequencing, as first-line diagnostic method for young children with seizures. Specific genetic factors were found to be the cause of epilepsy in 40 percent of patients evaluated for first presentation with seizures. Genetic testing also yielded a diagnosis in 25 percent of children who had epilepsy with an otherwise unknown cause.

Released: 28-Jul-2017 4:35 PM EDT
Study Examines the Safest Hypothermia Treatment for Newborns
Children's Hospital of Michigan

After more than 20 years of research on the best treatment for full-term infants affected by oxygen deprivation during the birthing process, Seetha Shankaran, M.D., neonatologist at DMC Children's Hospital of Michigan and DMC Hutzel Women's Hospital, served as the lead investigator in a definitive Journal of the American Medical Association study that documented the safest depth and duration of body-cooling to minimize injury from hypoxic ischemic encephalopathy (HIE) in newborns.

Released: 26-Jul-2017 12:05 PM EDT
Opting for Weight-Loss Surgery at Lower BMIs May Be Best for Patients’ Health, Study Suggests
Michigan Medicine - University of Michigan

The struggle to escape obesity is pointing more Americans toward bariatric surgery. But a new study shows that only one in three patients who have an operation succeed in getting their body-mass index below 30, the cutoff for obesity, in the first year. The odds were better for those who had surgery while they were still below a “morbid obesity” BMI of 40.

24-Jul-2017 12:00 PM EDT
Unit History of Suicide Attempt Increases Suicide Risk for Troops
Uniformed Services University of the Health Sciences (USU)

Does a previous suicide attempt in a soldier’s unit increase the risk of additional suicide attempts? According to a study, “Risk of Suicide Attempt Associated with Previous Attempts in One’s Army Unit,” published July 26, 2017 in JAMA Psychiatry, the answer is yes.

Released: 24-Jul-2017 10:05 AM EDT
Despite Lack of FDA Approval, Stem Cell Centers Claim to Offer Effective Treatment for Patients with Heart Failure
Saint Louis University Medical Center

Stem cell centers claim to offer effective treatment to patients with heart failure, despite the fact that the treatment is not approved for such use by the U.S. Food and Drug Administration (FDA), says the author of research letter in the current issue of JAMA Internal Medicine.

Released: 12-Jul-2017 11:00 AM EDT
Mount Sinai Researchers Find No Statistically Significant Risk of Intellectual Disability in Children Born to Mothers Treated with Antidepressants
Mount Sinai Health System

In a first-of its kind study, researchers from the Icahn School of Medicine at Mount Sinai found an elevated risk of intellectual disability (ID) in children born to mothers treated with antidepressants, but the risk was not statistically significant and is likely due to other factors, including parental age and the parents’ psychiatric history.

Released: 6-Jul-2017 9:00 AM EDT
Late Teen Years Are Key Period in Bone Growth
Children's Hospital of Philadelphia

The late adolescent years are an important period for gaining bone mineral, even after a teenager attains his or her adult height. Scientists analyzing a racially diverse, multicenter sample from a large, federally funded national study say their findings reinforce the importance of diet and physical activities during the late teen years, as a foundation for lifelong health.

Released: 29-Jun-2017 10:00 AM EDT
Success With First 20 Patients Undergoing Minimally Invasive Pancreatic Transplant Surgery
Johns Hopkins Medicine

Surgeons at Johns Hopkins Medicine report that their first series of a minimally invasive procedure to treat chronic pancreas disease, known as severe pancreatitis, resulted in shorter hospital stays, less need for opioids and fewer complications, compared with standard surgical approaches.

27-Jun-2017 8:05 AM EDT
Acupuncture May Not Be Effective in Treating Infertility
Penn State College of Medicine

Acupuncture, alone or with the medication clomiphene, does not appear to be effective in treating infertility in women with polycystic ovary syndrome (PCOS), according to a new international study including Penn State College of Medicine.

Released: 26-Jun-2017 12:05 PM EDT
Review: Insomnia Medication May Wake Up Some Patients From Vegetative State
Michigan Medicine - University of Michigan

A systematic review of zolpidem for noninsomnia neurological disorders, including movement disorders and disorders of consciousness, finds reason for additional research.

21-Jun-2017 11:00 AM EDT
HPV Testing Leads to Earlier Detection and Treatment of Cervical Precancer
University of New Mexico Comprehensive Cancer Center

Women who receive human papillomavirus (HPV) testing, in addition to a pap smear, receive a faster, more complete diagnosis of possible cervical precancer, according to a study of over 450,000 women by Queen Mary University of London (QMUL) and the University of New Mexico (UNM) Comprehensive Cancer Center.

Released: 14-Jun-2017 4:05 PM EDT
How Do Preemies Perform in School?
Northwestern University

Parents of prematurely born babies often fear their children may go on to struggle in school, but findings from a new large-scale study from the Institute for Policy Research at Northwestern University and Northwestern Medicine should reassure parents.

   
Released: 14-Jun-2017 8:00 AM EDT
Study Finds One in Five Hospitalized Adults Suffer Side Effects From Prescribed Antibiotics
Johns Hopkins Medicine

A study examining the impact of antibiotics prescribed for nearly 1500 adult patients admitted to The Johns Hopkins Hospital found that adverse side effects occurred in a fifth of them, and that nearly a fifth of those side effects occurred in patients who didn't need antibiotics in the first place.

8-Jun-2017 3:05 PM EDT
Motor Vehicle Crash Risk for Teens with ADHD Much Lower Than Previously Reported
Children's Hospital of Philadelphia

Adolescent drivers with attention-deficit hyperactivity disorder (ADHD) have a 36 percent higher crash risk than other newly licensed teens. Although elevated, this risk is far lower than previous reports of being four times higher. This is the first large-scale study to provide detailed information on crash risk of adolescents with ADHD compared to other newly licensed young drivers.

8-Jun-2017 5:00 PM EDT
Is the Finger-Stick Blood Test Necessary for Type 2 Diabetes Treatment?
University of North Carolina Health Care System

In a landmark study, UNC School of Medicine researchers have shown that blood glucose testing does not offer a significant advantage in blood sugar control or quality of life for type 2 diabetes patients who are not treated with insulin.

1-Jun-2017 5:45 PM EDT
Study Finds Rate of Mastectomies Decreases with Adoption of Breast Tumor Margin Guidelines: What This Means in the Overtreatment Debate for Breast Cancer
Memorial Sloan Kettering Cancer Center

In a dramatic shift since the publication of margin guidelines for breast cancer surgery, lumpectomy rates have substantially increased and more-aggressive surgical options have been used less often, according to research findings from a new study being presented at the 2017 annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago. The study will also be published in a corresponding issue of JAMA Oncology.

Released: 31-May-2017 2:05 PM EDT
Study Suggests Lower Targets for Systolic Blood Pressure
Tulane University

A new study conducted by researchers from Tulane University finds reducing target systolic blood pressure below current recommendations significantly reduces the risk of cardiovascular disease and preventable death.

Released: 30-May-2017 12:05 PM EDT
Quality Improvement Measures Reduce Hospital Readmissions but Do Not Produce Consistent Savings, Study Shows
Cedars-Sinai

Efforts to reduce hospital readmissions are working, but they’re not always saving money, according to a new Cedars-Sinai study. The study, published today in the Journal of the American Medical Association Internal Medicine, evaluated the effectiveness and financial benefit of quality improvement programs at medical centers in the U.S. and elsewhere.

26-May-2017 2:05 PM EDT
Do Obese Children Need to Attend Treatment to Lose Weight?
UC San Diego Health

One-third of American children are overweight or obese. Family-based treatment (FBT) has been considered the best model for the treatment of obese children as it provides both parents and children with education and behavior therapy techniques but is provided mainly in a hospital setting. Researchers at University of California San Diego School of Medicine have found that parent-based therapy (PBT) has similar outcomes to FBT and could be more cost-effective.

Released: 30-May-2017 10:00 AM EDT
Emergency Room Patients Routinely Overcharged, Study Finds
Johns Hopkins Medicine

An analysis of billing records for more than 12,000 emergency medicine doctors across the United States shows that charges varied widely, but that on average, adult patients are charged 340 percent more than what Medicare pays for services ranging from suturing a wound to interpreting a head CT scan.

Released: 23-May-2017 8:05 AM EDT
Probing Problems with Bariatric Surgery: Reoperations, Variation Are Common
Michigan Medicine - University of Michigan

Every year, nearly 200,000 Americans turn to surgeons for help with their obesity, seeking bariatric surgery to lose weight and prevent life-threatening health problems. But after more than two decades of steadily increasing numbers of operations, American bariatric surgery centers still vary greatly in the quality of care they provide.

Released: 22-May-2017 12:05 PM EDT
Study Shows Navigation Program Improves Longevity of Care for Youth with HIV in America
University of Alabama at Birmingham

Adherence to care improves when youth with HIV receive education and help navigating the system, according to study out of UAB.

19-May-2017 5:00 PM EDT
Starting Statins in Older Patients Not Effective as Preventive Care
NYU Langone Health

A study from NYU Langone Medical Center researchers published in JAMA Internal Medicine finds that initiating statins in heart-healthy older adults may not extend lifespan.

19-May-2017 10:05 PM EDT
Penn Study Pinpoints Accuracy of ICU Doctors’ and Nurses’ Predictions of Patient Outcomes
Perelman School of Medicine at the University of Pennsylvania

Physicians in intensive care units routinely consider their patients’ chances of survival and recovery when guiding patients and family members in making important decisions about care plans. A new study is shedding light on the accuracy of those judgments — and for the first time also reveals the accuracy of ICU nurses’ predictions of patient outcomes. For example, the study shows that ICU physicians are better at predicting whether patients will be alive in six months than they are at predicting patients’ cognitive function in six months, and the more confident doctors are when making predictions, the more accurate those predictions tend to be.

18-May-2017 2:05 PM EDT
Nursing Homes Cut Urinary Tract Infections in Half Through Focused Effort on Catheter Care
Michigan Medicine - University of Michigan

A new study shows a way to keep urinary catheters from posing as much of a risk to the 1.4 million Americans currently in long-term and post-acute care. The research shows that urinary tract infections related to catheters fell by 54 percent in 404 nursing homes in 38 states that took part in a national patient safety effort.

12-May-2017 11:05 AM EDT
Strategy Significantly Boosts Colorectal Screening for Groups with Low Rates
University of North Carolina Health Care System

Researchers report in the Journal of the American Medical Association Internal Medicine that providing one-on-one support and customized tools for decision-making increased screening rates for patients at two community health centers in North Carolina and New Mexico.

Released: 8-May-2017 11:30 AM EDT
NIH-Funded Clinical Trial Shows Systemic Therapy Outperforms Intraocular Implant for Uveitis
NIH, National Eye Institute (NEI)

Systemic therapy consisting of corticosteroids and immunosuppressants preserved vision of uveitis patients better – and had fewer adverse outcomes – than a long-lasting corticosteroid intraocular implant, according to a clinical trial funded by the National Eye Institute (NEI). After seven years, visual acuity on average remained stable among participants on systemic therapy but declined by an average of six letters (about one line on an eye chart) among participants who had the implant. NEI is part of the National Institutes of Health.

Released: 5-May-2017 10:05 AM EDT
Coding, Machines May Decrease False Positives in Breast Cancer Screenings
Seattle Cancer Care Alliance

Machine learning (or coding) could help reduce false positives from mammography screening, according to an article study published online in the May 4, 2017 issue of the Journal of the American Medical Association (JAMA) Oncology. The national coding competition known as the DREAM Challenge, launched during the inauguration of Vice President Biden’s Cancer Moonshot Challenge, may help mitigate this harm associated with routine screening.

Released: 4-May-2017 11:00 AM EDT
NIH Launches Competition to Develop Human Eye Tissue in a Dish
NIH, National Eye Institute (NEI)

The National Eye Institute (NEI), part of the National Institutes of Health, has opened the first stage of a federal prize competition designed to generate miniature, lab-grown human retinas. The retina is the light- sensitive tissue in the back of the eye. Over the next three years pending availability of funds, NEI plans to offer more than $1 million in prize money to spur development of human retina organoids.

2-May-2017 3:05 PM EDT
Large Data Set Brings Precision to Breast Cancer Diagnosis and Care
University of Chicago Medical Center

Although the odds of developing breast cancer are nearly identical for black and white women, black women are 42 percent more likely to die from the disease. A large, multi-institutional study, published on-line May 4, 2017, in JAMA Oncology, explores the germline genetic variations and tumor biological differences between black and white women with breast cancer.

Released: 2-May-2017 11:05 AM EDT
Can You Feast While Dieting?
University of Illinois Chicago

Alternate-day fasting diets are just as effective as diets that restrict calories every day, researchers at the University of Illinois at Chicago report. The study, published in JAMA Internal Medicine, followed 100 obese adults for a year.

Released: 28-Apr-2017 12:30 PM EDT
Counting the Cuts in Mohs Surgery: A Way to Improve Care and Reduce Costs
Johns Hopkins Medicine

In an analysis of Medicare billing data submitted by more than 2,300 United States physicians, researchers have calculated the average number of surgical slices, or cuts, made during Mohs micrographic surgery (MMS), a procedure that progressively removes thin layers of cancerous skin tissue in a way that minimizes damage to healthy skin and the risks of leaving cancerous tissue behind.

Released: 26-Apr-2017 3:05 PM EDT
Readmission Penalties Don’t Correlate to Heart Attack Outcomes
UT Southwestern Medical Center

A program that penalizes hospitals for high early readmission rates of heart attack patients may be unfairly penalizing hospitals that serve a large proportion of African-Americans and those with more severe illness, a study by UT Southwestern Medical Center researchers suggests.

Released: 24-Apr-2017 4:05 PM EDT
JAMA Study, Clinical Trials Offer Fresh Hope for Kids with Rare Brain Disease
UT Southwestern Medical Center

Anna Gunby can’t run around as smoothly as most 4-year-olds because her wobbly legs are affected by a rare brain disease that also hinders her intellect. She can’t identify colors. She can’t count objects. Her attention span is short.

Released: 24-Apr-2017 11:00 AM EDT
Physicians Vastly Underestimate Patients' Willingness to Share Sexual Orientation, Study Finds
Johns Hopkins Medicine

A study that surveyed a national sample of emergency department health care providers and adult patients suggests that patients are substantially more willing to disclose their sexual orientation than health care workers believe.

19-Apr-2017 1:55 PM EDT
Displaying Lab Test Costs in Electronic Health Records Doesn’t Deter Doctors from Ordering Them
Perelman School of Medicine at the University of Pennsylvania

Hospitals nationwide are seeking ways to use price transparency – displaying the price of lab tests at the time when doctors are placing the order – to nudge doctors to consider whether the benefits are worth the cost. But, results of a new study show that simply displaying the Medicare allowable fees did not have an overall impact on how clinicians ordered these tests.

Released: 20-Apr-2017 3:05 PM EDT
Research Examines Effects of Early Preventive Dental Care in Medicaid-Enrolled Children
Texas A&M University

Contrary to prevailing wisdom, preventive visits to a dentist for children under 2 years old may not reduce the need for more care later, at least among those children enrolled in Medicaid in Alabama, according to a study published in the journal JAMA Pediatrics.

Released: 13-Apr-2017 6:05 PM EDT
Research Suggests Trans Fat Bans Lessen Health Risks
University of Chicago Medical Center

People living in areas that restrict trans fats in foods had fewer hospitalizations for heart attack and stroke compared to residents in areas without restrictions, according to a new study conducted by researchers at the University of Chicago Medicine and Yale School of Medicine.

Released: 13-Apr-2017 2:05 PM EDT
Quest for Balance in Radiation Leads to Lower Doses
UCSF Helen Diller Family Comprehensive Cancer Center

New UC Project Finds Roadmap to Improve Patient Safety in Radiation Exposure

10-Apr-2017 1:05 PM EDT
From Opioid-Free to Long-Term User, in One Operation: Study Shows Key Role of Surgery
Michigan Medicine - University of Michigan

Having surgery always comes with risks. But a new study suggests a new one to add to the usual list: the risk of becoming a long-term opioid user. About 6 percent of people who hadn’t been taking opioids before their operation, but were prescribed the drugs to ease their post-surgery pain, were still getting the drugs three to six months later, the study finds.

Released: 11-Apr-2017 2:35 PM EDT
JAMA Study Provides Further Support for Spinal Manipulation for Acute Low Back Pain
American Chiropractic Association

A new study published in the Journal of the American Medical Association (JAMA), adds to a growing body of recent research supporting the use of spinal manipulative therapy (SMT) as a first line treatment for acute low back pain, according to the American Chiropractic Association (ACA).

Released: 5-Apr-2017 12:05 PM EDT
When the Doctor Recommends Against the Surgery a Breast Cancer Patient Wants
Michigan Medicine - University of Michigan

A new study from the University of Michigan Comprehensive Cancer Center examines the complex interaction between patients’ desires for contralateral prophylactic mastectomy and surgeons’ responsibility to minimize harm.

Released: 3-Apr-2017 12:05 PM EDT
Risk of Data Breaches at Hospitals Is Greater at Larger Facilities and Those with Major Teaching Mission
Johns Hopkins University Carey Business School

The risk of data breaches at U.S. hospitals is associated with larger facilities and hospitals that have a major teaching mission, according to a study published online today by JAMA Internal Medicine.

27-Mar-2017 12:05 PM EDT
Electronic Health Records Improve Weekend Surgery Outcomes
Loyola Medicine

Electronic health record systems significantly improve outcomes for patients who undergo surgeries on weekends, according to a Loyola Medicine study published in JAMA Surgery.

23-Mar-2017 5:00 PM EDT
Gastric Acid Suppression Medications Increase Risk for Recurrence of Clostridium difficile Infection
Mayo Clinic

Researchers at Mayo Clinic have found patients who use gastric suppression medications are at a higher risk for recurrent Clostridium difficile (C-diff) infection. C-diff is a bacterium that can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon. The study is published in JAMA Internal Medicine.

21-Mar-2017 12:30 PM EDT
Preterm Births More Common in Mothers Who Are Cancer Survivors
University of North Carolina Health Care System

In a study published in the journal JAMA Oncology, UNC Lineberger Comprehensive Cancer Center researchers report that women diagnosed and treated for cancer during their childbearing years more commonly gave birth prematurely, and to babies whose weights were below normal ranges. Cancer survivors also had a slightly higher rate of cesarean section deliveries.



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