After common plastic surgery procedures, obese patients have more complications and make more hospital visits—leading to higher healthcare costs, reports a study in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Researchers are making progress toward developing effective approaches to early detection and intervention for psychosis—with the goal of lessening the impact or even preventing the development of schizophrenia and other psychotic disorders. Recent developments in early detection and intervention for psychosis are presented in the May special issue of The Journal of Nervous and Mental Disease, published by Wolters Kluwer.
For more than 100 years, exposing students to basic and clinical research has been an essential component of a medical school education in the United States. However, today, new models of medical education in which research plays a minimal role are likely to create a two-tiered system of education, decrease the physician-scientist pipeline and diminish the application of scientific advances to patient care.
University of Pennsylvania School of Nursing Announces Major General Margaret C. Wilmoth as Commencement Speaker on May 18, 3 p.m. at the Kimmel Center for the Performing Arts in Philadelphia
Researchers discover the role of a major cytokine in multiple sclerosis that could be a target for new therapy against the disease.
Stacey Cahn, PhD, associate professor of psychology at Philadelphia College of Osteopathic Medicine, explains how food sciences contributes to overeating.
A simple method of testing "twilight vision" gives reliable results in identifying people who have decreased visual acuity under low light conditions, according to a study in the May issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.
Ultrasound has become an essential tool for diagnostic and procedural uses in the critical care environment. The May issue of Anesthesia & Analgesia outlines a new set of basic ultrasound learning skills developed specifically for use in anesthesiology-critical care medicine (ACCM) training programs.
Interventional treatments—especially surgery—provide good functional outcomes and a high cure rate for patients with lower-grade arteriovenous malformations (AVMs) of the brain, reports the May issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Wolters Kluwer.
Doctors, lawyers and other “high level” professionals may have a built-in survival edge if they’re diagnosed with the disease frontotemporal dementia (FTD), according to new research from the Perelman School of Medicine at the University of Pennsylvania. Their work is published in this week’s issue of Neurology.
Penn translational med pioneer advocates that to “influence emergence of the clinic of the future, one designed to practice precision medicine,” an NIH plan to establish large-scale collaborative clinical trials needs also to pay better attention to three areas of emerging practice: adaptive clinical trials, merging EMRs and biobanks, and human phenotyping.
In the largest genome-wide analysis of common variable immunodeficiency disorder (CVID), scientists identified a gene that may be a "missing link" between overactive and underactive immune activity.
In the first major study to examine the use of a computer-assisted, photo-driven differential diagnosis generator for skin conditions, researchers at the Perelman School of Medicine at the University of Pennsylvania found physicians routinely used the tool, without an increase in calling for inpatient dermatology consultations.
As computers continue to shrink—moving from desks and laps to hands and wrists—memory has to become smaller, stable and more energy conscious. A group of researchers from Drexel University’s College of Engineering is trying to do just that with help from a new class of materials, whose magnetism can essentially be controlled by the flick of a switch.
Brain researchers from the Perelman School of Medicine at the University of Pennsylvania have developed a new brain mapping model which could improve the success rate of transcranial magnetic stimulation (TMS) in treating conditions including depression, neuropathic pain, and stroke. The model helps pinpoint target sites during TMS, a procedure that uses magnetic fields to stimulate nerve cells in the brain to alleviate or eliminate symptoms of stroke, depression, and attention disorders. The new model will be presented at the 67th American Academy of Neurology Annual Meeting in Washington, D.C. on Wednesday, April 22.
The Saint Joseph’s University Board of Trustees today elected Mark C. Reed, Ed.D., as the Jesuit institution’s 28th — and first lay — president in its 164-year history. Dr. Reed currently serves as senior vice president and chief of staff at Fairfield University.
The lab of Kristen Lynch, PhD studies how this splicing occurs in T cells and how it is regulated by multiple proteins. A new study describes a cascade of events that may explain changes in gene expression that occur during the development of the human immune system.
Critical questions about life outcomes beyond clinical interventions are the focus of a report issued today from Drexel University’s A.J. Drexel Autism Institute, from its Life Course Outcomes Research Program. The “National Autism Indicators Report: Transition into Young Adulthood” is a comprehensive report (available free online) that presents new findings about a wide range of experiences and outcomes of youth on the autism spectrum between high school and their early 20s, including new safety and risk indicators for young adults with autism. The report describes the indicators now available and serves as a call to action to fill the remaining large gaps in knowledge.
New research from the Monell Center reveals that tumor necrosis factor (TNF), an immune system regulatory protein that promotes inflammation, also helps regulate sensitivity to bitter taste. The finding may explain taste abnormalities and decreased food intake associated with infections, autoimmune disorders, and chronic inflammatory diseases.
Two Monell Center scientists have been recognized by the Association for Chemoreception Sciences (AChemS) for their contributions to the understanding of the senses of taste and smell. Robert F. Margolskee, MD, PhD, the Center’s Director and President, and Joel Mainland, PhD, Louise Slade Assistant Member, will be honored at the upcoming 2015 AChemS Annual Meeting.
Use of either proximal embolic protection devices (P-EPDs) or distal filter embolic protection devices (F-EPDs) during elective carotid artery stenting results in low rates of in-hospital stroke and death, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania. The study, published in JACC: Cardiovascular Interventions, found that although P-EPDs have been theorized to be more effective than F-EPDs at preventing stroke during carotid artery stenting, this first comparative effectiveness study revealed no statistically significant difference between the two devices.
Once again, researchers at Penn’s Abramson Cancer Center have extended the reach of the immune system in the fight against metastatic melanoma, this time by combining the checkpoint inhibitor tremelimumab with an anti-CD40 monoclonal antibody drug.
The PD-1 inhibitor pembrolizumab, a cancer immunotherapy drug, shrank or halted growth of tumors in 76 percent of patients with pleural mesothelioma, a rare and deadly form of cancer that arises in the outer lining of the lungs and internal chest wall, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania. Patients diagnosed with the disease, which is tied to exposure to asbestos, have a median survival rate of about one year.
Genetically modified versions of patients’ own immune cells successfully traveled to tumors they were designed to attack in an early-stage trial for mesothelioma and pancreatic and ovarian cancers at the Perelman School of Medicine at the University of Pennsylvania. The data adds to a growing body of research showing the promise of CAR T cell technology. The interim results will be presented at the American Association for Cancer Research (AACR) Annual Meeting 2015, April 18-22.
The American Academy of Neurology today launched a new online medical journal, titled Neurology® Genetics, to provide neurologists and scientists interested in applying findings from basic science with peer-reviewed articles, editorials and reviews to enhance patient care, education, and clinical research.
Understanding the molecular signals that guide early cells in the embryo to develop into different types of organs provides insight into how tissues regenerate and repair themselves. By knowing the principles that underlie the intricate steps in this transformation, researchers will be able to make new cells at will for transplantation and tissue repair in such situations as liver or heart disease.
There has been debate in the field about whether non-medically required induction of labor leads to a greater likelihood of C-section. A new analysis found no link between induction and rates of C section in uncomplicated pregnancies.
By using existing human drugs to improve metabolism and lifespan in microscopic worms, researchers have set the stage for clinica trials of possible innovative therapies for mitochondrial diseases. These diseases currently have few treatments.
The University of Oklahoma will host Environmental Journalism 2016, the 25th Annual Conference of the Society of Environmental Journalists (SEJ). SEJ’s meeting will bring 600 journalists and news-makers to Norman, Oklahoma October 7-11, 2015 for a comprehensive agenda of tours and sessions. See http://www.sej.org/initiatives/sej-annual-conferences/AC2015-agenda for details, and information on exhibitor opportunities.
Most people who attempt suicide make some type of healthcare visit in the weeks or months before the attempt, reports a study in the May issue of Medical Care, published by Wolters Kluwer.
The perioperative surgical home (PSH) is an emerging approach to improve care for patients undergoing surgery, and anesthesiologists are preparing to play a key role in leading it. But how will the PSH approach affect patients, the health care system, and the specialty of anesthesiology? These urgent questions are addressed by a coalition of senior anesthesiologists in a special article published by Anesthesia & Analgesia.
A new collaborative study describes a way that lung tissue can regenerate after injury. The team found that lung tissue has more dexterity in repairing tissue than once thought.
Emergency department patients have misperceptions about opioid dependence and want more information about their pain management options, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania. The study, published online in the Annals of Emergency Medicine, found that patients seen in the emergency department for acute pain expressed a desire for better communication from physicians about their pain management options, along with discussion of the risks of opioid dependence.
Researchers from Drexel University’s Privacy, Security and Automation Lab are using social network analysis tools to better understand the activity of cybercrime forums. Their findings could guide the next generation of “Untouchables.”
Once more, the multifactorial and heterogeneous nature of breast cancer fascinates researchers and is newly confirmed and re-interpreted in light of the results of a study entitled “Metformin and breast cancer: basic Knowledge in clinical context” published in April 2015 in the international journal Cancer Treatment Reviews.
The laboratory of David Weiner, PhD, received the Award for Best Academic Research Team, at the World Vaccine Congress in Washington, DC this week.
The dispersant used to remediate the 2010 Deepwater Horizon oil spill in the Gulf of Mexico is more toxic to cold-water corals at lower concentrations than the spilled oil, according to a new study that comes on the eve of the spill’s fifth anniversary, April 20th.
New research findings at University of the Sciences into how and why seniors fall may provide healthcare providers with insight on improved balance and strength-training strategies to prevent tumbles by the elderly.
Changes in employee health risk factors have a significant impact on work productivity, reports a study in the April Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).
In a study involving more than 31,000 women with cancer-causing mutations in the BRCA1 or BRCA2 genes, researchers at The Basser Center for BRCA, the Abramson Cancer Center, and the Perelman School of Medicine at the University of Pennsylvania identified mutations that are associated with significantly different risks of breast and ovarian cancers.
Good beer doesn’t happen by accident—it’s a science that participants in USciences’ first Brewing Science Certificate class will learn when it starts in the fall of 2015.
The International Anesthesia Research Society (IARS) is pleased to announce that one of its Trustees, Davy Cheng, MD, is the recipient of the Canadian Anesthesiologists’ Society 2015 Gold Medal Award. The Gold Medal Award is the highest award of the CAS and recognizes individuals who have made significant contributions to anesthesia in Canada through teaching, research, professional practice or related administration and personal leadership.
Researchers discovered that visual cues associated with overweight or obese people can influence one’s sense of smell, and that the perceiver’s body mass index matters, too.
The NCCN Foundation® has awarded its fifth series of Young Investigator Awards to six oncology researchers from NCCN Member Institutions; the awards provide grants of $150,000 over a two-year period for research initiatives focused on assessing and improving outcomes in cancer care.
In the largest study to date documenting the significant risks to children’s health associated with prescription antipsychotics, results suggest that initiating antipsychotics may elevate a child’s risk not only for significant weight gain, but also for Type II diabetes by nearly 50 percent.
Delving into the world of the extremely small, researchers are exploring how biodegradable nanoparticles can precisely deliver anticancer drugs to attack neuroblastoma, an often-deadly children's cancer.
The third and final roundtable of the NCCN 20th Annual Conference explored essential elements of clinical practice guidelines, as well as the historical development of the NCCN Guidelines®.
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