Researchers Identify Subtle Changes that May Occur in Neural Circuits Due to Cocaine Addiction
Mount Sinai Health System–– A research team from the Friedman Brain Institute of the Icahn School of Medicine at Mount Sinai published evidence showing that subtle changes of inhibitory signaling in the reward pathway can change how animals respond to drugs such as cocaine. This is the first study to demonstrate the critical links between the levels of the trafficking protein, the potassium channels’ effect on neuronal activity and a mouse’s response to cocaine. Results from the study were published in the peer-reviewed journal Neuron earlier this month.