To create prototype suction cups that are capable of glomming onto rough, wet surfaces and staying there, Ditsche has found inspiration in an aptly-named marine creature: the clingfish.
Cornell and Weill Cornell Medicine researchers report on the use of biomaterials-based organoids in an attempt to reproduce immune-system events and gain a better understanding of B cells.
A common species of zooplankton—the smallest animals in the freshwater food web—can evolve genetic tolerance to moderate levels of road salt in as little as two and a half months, according to new research published online today in the journal Environmental Pollution.
One potential is to create some sort of biomimetic earwax adhesive surface that can be used in a ventilation system for robotics or for other kinds of machinery.
Biologists on the Florida campus of The Scripps Research Institute (TSRI) have discovered a new mechanism that likely underlies how we feel force or touch.
Scientists at the University of North Carolina School of Medicine have developed a method to control proteins inside live cells with the flick of a switch, giving researchers an unprecedented tool for pinpointing the causes of disease using the simplest of tools: light.
In a microscopic feat that resembled a high-wire circus act, Johns Hopkins researchers have coaxed DNA nanotubes to assemble themselves into bridge-like structures arched between two molecular landmarks on the surface of a lab dish.
A new $6.8 million, automated lab in the UAB Department of Hospital Labs analyzes between 4,000 and 5,000 tubes of blood every night, providing information to help guide patient care, while keeping watch for abnormal test results that require immediate notification to clinicians.
Columbia Engineering researchers have developed a way to manufacture microscale-sized machines from biomaterials that can safely be implanted in the body. Working with hydrogels, they have invented a new technique that stacks the soft material in layers to make devices that have three-dimensional, freely moving parts. The study demonstrates a fast manufacturing method they call “implantable microelectromechanical systems” (iMEMS). (Science Robotics 1/4/17)
Scientists on the Florida campus of The Scripps Research Institute (TSRI) have developed a new tool for studying the molecular details of protein structure.
Annette Rompel and her team of the Department of Biophysical Chemistry at the University of Vienna are investigating so-called polyoxometalates. These compounds exhibit a great diversity and offer the scientists a wide range of applications. In interaction with enzymes they can enable the crystallization of proteins. On the other hand, the polyoxometalates represent compounds with an enormous application potential in catalysis and materials science.
Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment—called environmental estrogens—can produce infertility, abnormal reproductive development, including “precocious puberty,” and promote breast cancer.
New molecular imaging technologies can make it easier to diagnose, monitor, and treat cancers while potentially saving patients from undergoing therapies that are likely to be ineffective and playing a role in minimizing side effects.
Tufts University engineers have created a new format of solids made from silk protein that can be preprogrammed with biological, chemical, or optical functions, such as mechanical components that change color with strain, deliver drugs, or respond to light.
Using a novel approach involving a key enzyme that helps regulate global nitrogen, University of California, Irvine molecular biologists have discovered an effective way to convert carbon dioxide (CO2) to carbon monoxide (CO) that can be adapted for commercial applications like biofuel synthesis.
Northwestern University scientists Thomas J. Meade and Joseph R. Moskal have been named 2017 Fellows of the National Academy of Inventors (NAI). Meade’s research has led to the development of electronic biosensors for the detection of DNA and proteins and the development of bioactivated magnetic resonance (MR) contrast agents for in vivo imaging of cancer. Moskal’s research has led to two rapid-acting antidepressants currently in clinical development.
Scientists have few good methods for manipulating and investigating G-protein signaling. Now, UNC scientists have developed small proteins to selectively block a certain type of G-protein signaling, creating a unique and powerful tool for studying cell processes that depend on this signaling.
Iowa State will lead the biorefinery program of the country's 10th -- and just recently announced -- Manufacturing USA Institute. The institute is dedicated to improving the productivity and efficiency of chemical manufacturing.
Scientific discovery can come from anywhere, but few researchers can say the answers to their questions would come from the pea-sized bones in the head of a six-foot-long, 200-pound prehistoric freshwater fish.
In an article published Dec. 20 in the journal eLife, researchers present a mathematical model that explores whether "publication bias" — the tendency of journals to publish mostly positive experimental results — influences how scientists canonize facts.
Miqin Zhang, a professor of materials science and engineering at the University of Washington, is looking for ways to help the body heal itself when injury, disease or surgery cause large-scale damage to one type of tissue in particular: skeletal muscle.
While it may look like a pine wreath dotted with crimson berries, this holiday-themed image is in fact one of the world’s first color electron micrographs.
A team of researchers in Italy set out to develop a simple, ultrasensitive fluorescence detection system of in-flow microRNAs that uses spectrally encoded microgels. As the team reports in Biomicrofluidics, until now such a multiplexed barcode detection approach has only been performed in time-consuming observation procedures, significantly hindering its possible diagnostic performance.
A rare and potent type of immune cell has been discovered around the brain, suggesting the cells may play a critical role in battling Alzheimer's, multiple sclerosis and other diseases. By harnessing the cells' power, doctors may be able to develop new treatments for disease, traumatic brain injury and spinal cord injuries – even migraines.
We studied beardogs and brewed our own lava. We designed a vortex laser to accelerate computing. We challenged the status quo when it comes to treating concussions, and we helped show why bite-mark analysis may not be a reliable form of evidence to use in criminal courts.
AMP has published guideline recommendations for both clinical laboratory professionals and oncologists that assess the status of next-generation sequencing (NGS)-based cancer tests and establish standardized classification, annotation, interpretation, and reporting conventions for somatic sequence variants.
Modeling blood flow through a stent graft put graduate student John Asiruwa on the path to a career in biomedical engineering, doing work that “can be life changing for patients.”
A ‘living bandage’ made from stem cells, which could revolutionise the treatment and prognosis of a common sporting knee injury, has been trialled in humans for the first time by scientists at the Universities of Liverpool and Bristol.
Gene variants associated with disease are typically considered faulty; problems arise when the proteins they make don't adequately carry out their designated role.
UT Southwestern Medical Center researchers developed a new imaging technique that makes X-ray images of proteins as they move in response to electric field pulses.
Biology isn't just for biologists anymore. That's nowhere more apparent than in the newly furnished lab in room 097 of the Shriram Center basement, where flasks of bacterial and animal cells, snug in their incubators, are churning out proteins destined for jobs they may not have done in nature.
Protecting the body against oxidative stress
Glenn Fleisig compiles biomechanical analysis from thousands of baseball players to find out what's behind the epidemic.
A biologist at The University of Texas at Dallas and his colleagues have discovered that two enzymes previously linked independently with keeping cancer cells alive actually work in tandem to spur tumor growth.
Scientists from the McEwen Centre for Regenerative Medicine, University Health Network, have developed the first functional pacemaker cells from human stem cells, paving the way for alternate, biological pacemaker therapy.
Cancer is the second leading cause of death in the U.S., making early, reliable diagnosis and treatment a priority. Miniaturized lab-on-chip approaches are prime candidates for developing viable diagnostic tests and instruments because they are small, need only limited test volumes, and can be cost-effective. Researchers have developed just such an approach capable of processing biomolecular samples from blood. They describe their work in this week’s Biomicrofluidics.
Dr. Delbert E. Day, a prolific inventor whose work with specialty glasses has led to treatments for cancer, bone tissue regeneration and wound care, has been named a National Academy of Inventors Fellow.
It has been 20 years since Dolly the sheep was successfully cloned in Scotland, but cloning mammals remains a challenge. A new study by researchers from the U.S. and France of gene expression in developing clones now shows why most cloned embryos likely fail.
New research led by scientists at The Scripps Research Institute (TSRI) reveals that a human enzyme has changed little from its days as a bacterial enzyme.
A team of scientists has uncovered details of the cellular mechanisms that control the direct programming of stem cells into motor neurons.
Scientists examined one bacterium found 1,000 feet underground (called Paenibacillus) that demonstrated resistance to most antibiotics used today, including so-called ‘drugs of last resort’ such as daptomycin. These microorganisms have been isolated from the outside world for more than four million years within the cave.
Prominent research leader and biomedical scientist Professor Barry Halliwell will help to steer biomedical research efforts in Singapore at the Agency for Science, Technology and Research (A*STAR) from 1 January 2017.
A Queen’s University Belfast expert is leading a €4m international initiative to investigate whether natural toxins and manmade chemicals are creating potentially dangerous mixtures that affect our natural hormones and cause major illnesses such as cancer, obesity, diabetes or infertility.
The patent relates to the use of Streck’s proprietary Cell-Free DNA BCT CE product for the collection of samples to analyze fetal nucleic acid for non-invasive prenatal testing (NIPT).
A new commentary cautions that the Food and Drug Administration’s ban on triclosan and 18 other biocidal chemicals that promote antibiotic resistance is only a starting point. Triclosan’s long-term impact, as well the risks substitute chemicals may pose, must also be addressed.
FAU's Schmidt College of Medicine recently appointed Janet Robishaw, Ph.D., as chair of the Department of Biomedical Sciences. Robishaw, an accomplished functional and translational genomics researcher with 30 years of sustained federal funding from the NIH, comes to FAU from Geisinger Health System in central Pennsylvania.
Demonstration that bacteria can drive mating in eukaryotes raises possibility that environmental bacteria or bacterial symbionts may influence mating in animals
More than 46,000 species of spiders creepy crawl across the globe. Each one produces a venom composed of an average of 500 distinct toxins, putting the conservative estimate of unique venom compounds at more than 22 million. Researchers are studying these toxins to increase our understanding of the evolution of spider venom and contribute to the development of new medicines, anti-venoms and research tools.
Marathon event highlights coding and biotech skills to develop solutions related to food, agriculture and healthcare technology
As part of an effort to develop drought-resistant food and bioenergy crops, scientists at the Department of Energy’s Oak Ridge National Laboratory have uncovered the genetic and metabolic mechanisms that allow certain plants to conserve water and thrive in semi-arid climates.
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