Penn Medicine’s Basser Center for BRCA announced $375,000 in new grant funding to support BRCA-focused research projects across the nation. The grants are aimed at advancing the care of patients living with BRCA1 and BRCA2 mutations.
The marijuana extract tetrahydrocannabinol (THC) isn't effective in preventing nausea and vomiting after surgery in patients at high risk of this common complication, reports a study in Anesthesia & Analgesia.
Researchers have a new genome screen that has identified partner molecules of cell-waste disposal proteins. They applied their new method to identify other clock partners that target a multipurpose cell nucleus receptor for disposal.
PinnacleHealth CardioVascular Institute enrolled the first patient in Pennsylvania in a randomized trial studying a new heart valve to treat aortic valve disorders.
he whimsically named sonic hedgehog gene, best known for controlling embryonic development, also maintains the normal physiological state and repair process of an adult healthy lung, if damaged.
University of Pennsylvania’s Institute for Translational Medicine and Therapeutics’ 10th Annual International Symposium will cover translational science in academic medical centers and biotech along with the impact of innovative technologies such as super-resolution imaging, optogenetics, and the new gene editing tool CRISPR-Cas9.
Doctors explain how blood tests can be used to diagnose certain medical conditions.
Colorectal cancer will claim the lives of close to 50,000 Americans this year, according to the American Cancer Society. Screening is the most effective way to reduce the risk of dying from the disease, yet as a Penn Medicine physician argues in an editorial this week in the journal Gastroenterology, current recommendations to screen older people with a family history of colorectal cancer, specifically with colonoscopy every five years, is not justified for most patients. Chyke A. Doubeni, MD, MPH, chair of the department of Family Medicine and Community Health at the Perelman School of Medicine at the University of Pennsylvania, is the co-author of the editorial.
Talk about a return on a college investment: A new college scorecard by the U.S. Department of Education puts University of the Sciences graduates high on the list of top career earnings.
David Fajgenbaum, MD, MBA, MSc, a research assistant professor of Medicine, division of Hematology/Oncology, in the Perelman School of Medicine at the University of Pennsylvania, has received the RARE Champion of Hope award for science.
Beth Schwartz joins Jefferson and Nemours as a specialist in pediatric and adolescent gynecology to help families address girls’ needs from birth to early adulthood.
A less-common form of bariatric surgery can help the heaviest patients reach an ideal weight, but it’s not for everyone.
Nearly 30,000 organ transplants are performed in the United States every year. They routinely extend lives, but the success of these procedures continues to be limited by problems that arise when the recipient’s immune system rejects their new organ and other complications. Now, a large international team of transplant surgeons and scientists, co-led by researchers from the Perelman School of Medicine at the University of Pennsylvania, has come together to investigate the genetic factors behind transplant successes and failures. The project, involving more than three dozen research institutions around the world, is called the International Genetics & Translational Research in Transplantation Network (iGeneTRAiN). Their efforts are detailed in a pair of papers published today in Genome Medicine and in the journal Transplantation.
Using a novel synthetic platform for creating vaccines originally developed in the laboratory of David Weiner, PhD, a professor of Pathology and Laboratory Medicine from the Perelman School of Medicine at the University of Pennsylvania, a team led by his colleagues at the Johns Hopkins University School of Medicine, has successfully eradicated precancerous cervical lesions in nearly half of the women who received the investigational vaccine in a clinical trial.
Growing demand for more accessible and blended learning, the emergence of adaptive learning, and increased adoption of learning analytics are transforming the higher education landscape, according to the NMC Horizon Report: 2015 Higher Education Edition. In addition, a recent survey conducted by Wolters Kluwer of nursing school Deans identified computer-aided simulations, educational EHRs, and adaptive quizzing as growing requirements to Nursing School programs.
Fat grafting—taking fat from one area of the body and transferring it elsewhere—has become a widely used plastic surgery technique. But what's the best method of processing cells for fat grafting procedures? Available research data still can't settle that long-running debate, according to a review in the October issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
A study of influenza infection in animals broadens understanding of the immune response to flu virus, showing that the process is more dynamic than usually described. The findings may offer key insights for developing better vaccines.
With booming interest in dermal fillers for minimally invasive treatment of facial lines and wrinkles, plastic surgeons are looking for evidence to help them choose the product that will give the best results for their patients. A new, validated method for providing standard ratings of cohesivity for currently available hyaluronic acid (HA) gel fillers is reported in the October issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Dr. Antonia Novello, 14th U.S. Surgeon General, brought her wit and wisdom to students at Georgia Campus – Philadelphia College of Osteopathic Medicine this week as part of the Diversity Lecture Series. Speaking on the topic, “Health Policy Management in the 21st Century,” she shared healthcare disparity statistics, as well as medical school applicant information to highlight the need for a more diverse group of healthcare professionals. In addition, she issued a warning that in the year 2025, there may not be enough physicians to care for Americans.
Mitochondria are not only the power plants of our cells; these tiny structures also play a central role in our physiology. By enabling flexible responses to new environments, mitochondria have helped humans adapt and evolve.
Medications play an important role in managing patients with opioid use disorders, but there are not enough physicians with the knowledge and ability to use these often-complex treatments. New evidence-based recommendations on the use of prescription medications for the treatment of opioid addiction are published in the October/November Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine (ASAM). The journal is published by Wolters Kluwer.
Older adults with central vision loss caused by age-related macular degeneration (AMD) have no problem with accuracy in performing touch screen tasks, according to a study in the October issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.
Arteries contain higher numbers of circulating tumor cells than veins in uveal melanoma patients, raising a concern for standard technique for detection of tumor cells in the blood.
Every year at this time, we hear it's time to get the flu shot. After last year's vaccine missed the mark, how does the Center for Disease Control regain the public's confidence that their predictions will hold up this year? With the facts.
One company's program to improve employee well-being led to improvements in worker health and productivity while decreasing health care costs, reports a case study in the October Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).
In cancer patients nearing the end of life, certain subtypes of delirium—specifically, hypoactive and "mixed" delirium—are a strong indicator that death will come soon, reports a study in Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society. The journal is published by Wolters Kluwer.
Can women with low platelet counts safely undergo epidural/spinal anesthesia during labor? Available evidence suggests a low rate of complications related to abnormal blood clotting for this large group of patients, reports a study in Anesthesia & Analgesia.
Wolters Kluwer, a leading global provider of information and point of care solutions for the healthcare industry, today announced it has extended its successful publishing partnership with the American Heart Association (AHA). In place for nearly two decades, the longstanding partnership has evolved beyond traditional print publishing to include web and mobile platforms, as well as open access.
More than 40 attendees from U.S. Senate and House Congressional offices learned about issues related to science, technology, engineering, and math (STEM) education and workforce development at the "Materials Information Luncheon: Building the STEM Workforce for a Robust Economy."
Jefferson researchers identified a high risk for venous thromboembolism (VTE), or blood clots, following surgery for long-bone reconstruction in patients with metastatic cancer. They published the results in the Journal of Bone and Joint Surgery.
Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells. The researchers found that MYC protein may affect circadian rhythm and metabolism by promiscuously binding to promoter regions in key genes for maintaining these daily cycles.
An elevated infant death rate may be linked to mourning experienced by women in the months before they become pregnant, reports a study in Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society. The journal is published by Wolters Kluwer.
Researchers at Penn State have developed a new lab-on-a-chip cell sorting device based on acoustic waves.
The ethnic and cultural makeup of the United States is rapidly diversifying, with the U.S. Census Bureau projecting that 35 percent of the U.S. population will consist of ethnic minorities by 2020, up from 28 percent in 2010. This growth, coupled with a sharp spike in the number of individuals entering the healthcare system under the Affordable Care Act, means nurses are encountering more patients with greater cultural disparity—requiring a higher level of cultural sensitivity.
Jefferson expands its cancer treatment to analyze each tumor with the newest techniques and help doctors identify cutting edge treatment options.
Saint Joseph’s University will inaugurate Mark C. Reed, Ed.D., its 28th president on Friday, Sept. 18, during a ceremony in the Michael J. Hagan ’85 Arena.
Even patients with health insurance who have multiple myeloma may be vulnerable to “financial toxicity” because of the higher use of novel therapeutics and extended duration of myeloma treatment, researchers from Penn’s Abramson Cancer Center report in this week’s Lancet Haematology.
A generation ago, there was no such thing as pre-diabetes. Well, the condition existed – it just wasn’t given a name or diagnosed the way it is now.
A simple blood test can detect early markers of “reinvigorated” T cells and track immune responses in metastatic melanoma patients after initial treatment with the anti-PD-1 drug pembrolizumab.
Jefferson Health has added an On-Demand Virtual Care app to its telemedicine program. The app allows patients to connect with emergency medicine physicians via computers and mobile devices.
Knocking out one or both crucial regulatory genes caused cleft lip, skin barrier defects, and a host of other developmental problems in mice, hinting that abnormalities in these molecular pathways could underlie many birth defects that are presently not well understood.
Reporters wishing to request an interview should contact Ashwin Verghese at 215-204-7739 (office), 717-676-8584 (cell) or [email protected]. Photos are available upon request.
Anesthesiologists don't exploit insurance rules by "upcoding" patients' medical status in order to receive higher reimbursements for surgical anesthesia, suggests a study in Anesthesia & Analgesia.
Stacey Cahn, PhD, associate professor of clinical psychology at Philadelphia College of Osteopathic Medicine, offers insight into weight stigma--one of the most acceptable forms of discrimination.
Editing errors in the DNA of developing T and B cells can cause blood cancers. Now, researchers have shown that when the enzyme key to cutting and pasting segments of DNA hits so-called “off-target” spots on a chromosome, the development of immune cells can lead to cancer in animal models. Knowing the exact nature of these editing errors will be helpful in designing therapeutic enzymes based on these molecular scissors.
Like the hairs they resemble, cilia come in all lengths, from short to long. But unlike the hair on our heads, the length of sensory cilia on nerve cells in our noses is of far more than merely cosmetic significance. Researchers found a location-dependent pattern in cilia length in the mouse nasal cavity that affects sensitivity to odors. The discovery may also have important implications for the study of sight and touch.
New research from The Wistar Institute shows exactly how a known, highly selective small molecule telomerase inhibitor is able to bind with the enzyme, thus opening the possibility of developing more telomerase inhibitors that target this pocket of telomerase and could be clinically effective in a wide variety of cancer types.
Addressing the relatively small number of new cancer drugs for children, a selective group of leading research centers is joining a new federally funded research consortium aimed at bringing scientific rigor and a concentrated effort to identifying new drug candidates for pediatric clinical trials.
Targeting exhausted immune cells may change the prognosis for patients with acute myeloid leukemia (AML) relapse after a stem cell transplant, according to Penn State College of Medicine researchers.
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