For smokers, the number of cigarettes smoked per day and current body mass index are predictive of changes in weight after quitting smoking, according to researchers at Penn State College of Medicine.
Eye injections of the drug Avastin, used to treat retinal diseases, bring no greater risk of endophthalmitis, a potentially blinding eye infection, than injections with the much more expensive drug Lucentis made by the same company, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Their findings are published today in JAMA Ophthalmology.
Health care has much to learn from innovative high-tech companies, but not in the way most people think, according to a Perspective published today in the New England Journal of Medicine and authored by innovation experts from the Perelman School of Medicine and the Wharton School at the University of Pennsylvania. Innovation, they say, can most effectively achieve meaningful outcomes by testing many new ideas quickly, cheaply, and contextually.
Thousands of students across Greater Philadelphia will soon start the next chapter of their lives as they begin their college journeys away from home. But with their new freedom comes the exposure to millions of germs while living and studying in close quarters with others.
Tumor cells associated with pancreatic cancer often behave like communities by working with each other to increase tumor spread and growth to different organs. Groups of these cancer cells are better than single cancer cells in driving tumor spread.
New Curriculum Platform uses iPads to Meet Students Where They Are – On Mobile Devices
When most people think of eating disorders, they think of anorexia nervosa and bulimia nervosa. But there’s another condition that has nothing to do with concerns over weight, shape or body image, and it has been recognized in the latest edition of the Diagnostic and Statistical Manual of Mental Disorders.
While a new Penn Medicine study in this week’s Annals of Internal Medicine points to several promising cleaning tactics of “high-touch surfaces,” there’s a lack of evidence as to which is the most effective at reducing healthcare-associated infections (HAIs).
The editors of Plastic and Reconstructive Surgery® and Plastic and Reconstructive Surgery—Global Open®, the official medical journals of the American Society of Plastic Surgeons (ASPS), are pleased to announce the winners of the 2015 Best Paper Awards, recognizing outstanding new research and reviews from these leading plastic surgery journals.
Two Penn Medicine researchers from the Center for Clinical Epidemiology and Biostatistics (CCEB) have been honored with the 2015 Outstanding Statistical Application Award from the American Statistical Association, to be presented today at the Joint Statistical Meetings.
A large randomized clinical trial of an emergency department (ED)-based program aimed at reducing incidents of excessive drinking and partner violence in women did not result in significant improvements in either risk factor, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.
The National Science Foundation has funded a one-of-a-kind joint university/industry center to study and develop atomically thin coatings, led by Penn State.
PEDSnet, a national clinical research network co-led by a pediatric researcher at The Children’s Hospital of Philadelphia, was approved for an $8.6 million funding award by the Patient-Centered Outcomes Research Institute.
Results of a phase one trial show that an investigational topical drug, resiquimod gel, causes regression of both treated and untreated tumor lesions and may completely remove cancerous cells from both sites in patients with early stage cutaneous T cell lymphoma (CTCL) – a rare type of non-Hodgkin lymphoma that affects the skin. Currently, there is no cure for CTCL aside from a bone marrow transplant. However, the new study shows that the topical gel can eliminate malignant T cells, leading to diminished lesions.
New research from The Wistar Institute has identified an interaction between proteins that provides a pivotal role in organizing chromosomes during mitosis so that vital genetic information gets passed on safely.
Cancer researchers already know of some oncogenes and other factors that promote the development of colon cancers, but they don’t yet have the full picture of how these cancers originate and spread. Now researchers have illuminated another powerful factor in this process, by unraveling an additional pathway for the origin of colon cancer.
Back-to-school health story features stress, school bus safety, student-athlete situations, vaccinations, back packs, and food allergies.
Moles are benign tumors found on the skin of almost every adult. Scientists have known for years that a mutation in the BRAF gene makes them start growing, but until now haven’t understood why they stop. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania have identified a major genetic factor that keeps moles in their usual non-cancerous, no-growth state.
The American Society of Hematology (ASH) has awarded Nancy Speck, PhD, a professor of Cell and Developmental Biology in the Perelman School of Medicine at the University of Pennsylvania the 2015 Henry M. Stratton Medal for Basic Science for her “seminal contributions in the area of hematology research.”
Researchers analyzed circadian rhythms in abundance and type of microbiota in the gut and feces of mice using genetic sequencing. They found that the absolute abundance of a large group of rod-shaped bacteria common in the gut and skin of animals, and relative species make-up of the microbiome, changed over a 24-hour cycle, and this rhythmicity was more pronounced in female mice.
James Metz, MD, has been named the chair of the department of Radiation Oncology in the Perelman School of Medicine at the University of Pennsylvania.
The roughly nine million Americans who rely on prescription sleeping pills to treat chronic insomnia may be able to get relief from as little as half of the drugs, and may even be helped by taking placebos in the treatment plan, according to new research published today in the journal Sleep Medicine by researchers from the Perelman School of Medicine at the University of Pennsylvania. Their findings starkly contrast with the standard prescribing practices for chronic insomnia treatment.
Researchers have devised an entirely new approach to vaccines – creating immunity without vaccination. They demonstrated that animals injected with synthetic DNA engineered to encode a specific neutralizing antibody against the dengue virus were capable of producing the exact antibodies necessary to protect against disease, without the need for standard antigen-based vaccination. This approach, was rapid, protecting animals within a week of administration.
NCCN is now accepting original abstracts from investigators for consideration for the NCCN 21st Annual Conference General Poster Session; the deadline for submissions is Friday, November 6, 2015.
Georgia Campus - Philadelphia College of Osteopathic Medicine celebrates 10 years of impact. Since opening its doors in 2005, the college has generated millions of dollars in economic impact, created dozens of jobs and helped train hundreds of students to do more for themselves, the community and the world.
Edith Mitchell, M.D., Professor of Medical Oncology at Thomas Jefferson University, will be appointed as President of the National Medical Association (NMA) at the NMA’s 113th Annual Convention and Scientific Assembly in Detroit, Michigan on Tuesday August 4th.
A device to mix liquids utilizing ultrasonics is the first and most difficult component in a miniaturized system for low-cost analysis of sputum from patients with pulmonary diseases such as tuberculosis and asthma.
A new study questions the relevance of fish oil-derived substances and their purported anti-inflammatory effects in humans.
Working with yeast and worms, researchers found that incorrect gene expression is a hallmark of aged cells and that reducing such “noise” extends lifespan in these organisms.
Some women with breast cancer can now undergo a "one and done" approach combining nipple-sparing mastectomy with immediate single-stage implant (SSI) breast reconstruction in a single procedure, according to a report in the July issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
More women are expressing interest in plastic surgery to restore a more youthful figure after having children. An update on combined procedures for postpartum body contouring—addressing the abdomen, breasts, and other problem areas—is presented in the August issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Charging people to participate in research studies is likely to undermine the fundamental ethical basis of clinical research, according to a new paper written by bioethicists, including lead author Ezekiel Emanuel, MD, PhD, chair of the department of Medical Ethics and Health Policy at the Perelman School of Medicine at the University of Pennsylvania, and published in Science Translational Medicine. The paper outlines the arguments for and against the concept of “pay-to-play” research, ultimately concluding that this type of approach compromises the overall integrity of clinical research.
Surgeons at The Children’s Hospital of Philadelphia (CHOP) joined with colleagues from Penn Medicine recently to complete the world’s first bilateral hand transplant on a child. Earlier this month, the surgical team successfully transplanted donor hands and forearms onto eight-year-old Zion Harvey who, several years earlier, had undergone amputation of his hands and feet and a kidney transplant following a serious infection.
Eyes with central vision loss adapt by developing a new fixation point in a different part of the retina, called the preferred retinal location (PRL). Now for the first time, a new method makes it possible to identify PRLs in both eyes simultaneously, reports a study in the August issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.
Drexel University engineering researchers and students are joining an international effort led by PeaceTech Lab, a non-profit entity launched by the United States Institute of Peace (USIP), to prepare the next generation of humanitarian engineers. The PeaceTech Lab’s Young Engineers Program seeks to use the skills of talented young technologists in service of communities in conflict zones around the world who are seeking to create a sustainable peace.
Stillbirth or late termination of pregnancy due to severe fetal anomalies is a heartbreaking event for women and families—and one that poses challenges for all members of the healthcare team as they seek to provide empathic and supportive care, according to a special article in Anesthesia & Analgesia.
Patient satisfaction ratings after surgery for spinal degenerative disease—especially in terms of reduced pain and disability—are a good indicator of the procedure's effectiveness, reports a study in the August issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Wolters Kluwer.
Physicians in training are twice as likely to order a costly brand-name statin (used to lower blood cholesterol levels) when supervised by senior physicians who prefer those medications in their own practice, according to a new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania and published online in the Journal of General Internal Medicine.
The Food and Drug Administration recently announced it intends to require warning labels and child-resistant packaging on liquid nicotine products such as those used in e-cigarettes. But a professor of public health sciences at Penn State College of Medicine says nicotine poisoning is not a new problem.
The average wait time for a kidney transplant is five years and there are more than 100,000 people on the waiting list. However, there are thousands of viable hepatitis C-positive kidneys that are discarded each year solely because they’re infected. A new perspective paper in The New England Journal of Medicine suggests that “new antiviral therapies with cure rates exceeding 95 percent should prompt transplant-community leaders to view HCV (hepatitis C virus)-positive organs as a valuable opportunity for transplant candidates with or without pre-existing HCV infection.”
Tyrone Regional Health Network and Penn State Health have signed a letter of intent to enter into formal affiliation. With approval by organizational boards and state authorities, Tyrone Regional will become a member of Penn State Health.
Wills Eye Hospital is listed Top in Ophthalmology Nationwide once again this year on the much sought-after U.S. News & World Report’s Best Hospitals 2015-2016 Rankings. The annual list recognizes hospitals that excel in treating the most challenging cases. The list is compiled from votes by thousands of doctors nationwide.
A set of genes could help stratify African American men in need of more aggressive treatment for prostate cancer.
Using existing drugs, such as lithium, to restore basic biological processes in human cells and animal models, researchers may have broken a long-standing logjam in devising effective treatments for human mitochondrial diseases.
A new study from the Monell Center and collaborating institutions suggests that a single set of genes accounts for approximately 30 percent of person-to-person variance in sweet taste perception, regardless of whether the sweetener is a natural sugar or a non-caloric sugar substitute.
Workers with high job demands and job strain are at increased risk of sick leave due to mental disorders, reports a study in the August Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).
Increased radiation dose is associated with higher survival rates in men with medium- and high-risk prostate cancer, but not men with low-risk prostate cancer, according to a new study from Penn Medicine published this week in JAMA Oncology.
Did you belong to community, sports, or other clubs in your teens? If so, you might be more likely to survive into your late seventies, suggests a study in Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society. The journal is published by Wolters Kluwer.
A multi-disciplinary group of researchers and physicians at Thomas Jefferson University and Hospitals have created a clinical pathway to identify obstructive sleep apnea in higher-risk, hospitalized patients.
Hospitalizations for heart conditions, neurological illness, and other conditions were higher among people who live near unconventional gas and oil drilling (hydraulic fracturing), according to new research.
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