Wistar’s newly-created team of technology development professionals are in place to connect scientists’ research with translational science opportunities to form partnerships that will accelerate groundbreaking discoveries in medicine.
Contact lens wearers who don't follow certain hygiene habits have increased bacterial contamination of their contact lens cases, reports a study in the February issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
This feature provides tips from physicians on how those interested in getting a tattoo can protect themselves from also getting an unwanted disease during the tattoo process.
A recent Stanford Cancer Institute study shows that adherence to the NCCN Guidelines® for Colon Cancer in an integrated health care setting improves outcomes in all patients, including minorities.
Tens of millions of people worldwide have abnormal, leak-prone sproutings of blood vessels in the brain called cerebral cavernous malformations. These abnormal growths can lead to seizures, strokes, and hemorrhages, yet their precise molecular cause has never been determined. Now, cardiovascular scientists have studied this pathway in heart development to discover an important set of molecular signals, triggered by CCM-linked gene defects, that potentially could be targeted to treat the disorder.
The International Anesthesia Research Society (IARS) announces that Jean-François Pittet, MD, will succeed Steven L. Shafer, MD, as Editor-in-Chief of its flagship journal Anesthesia & Analgesia (A&A). Dr. Shafer’s current term expires in March 2016.
New Albright College research suggests contour integration impairment is trait-related or a symptom of schizophrenia.
Infants show distinct, consistent patterns of brain activity in response to painful vaccinations, reports a study in the February issue of PAIN®, the official publication of the International Association for the Study of Pain. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Workhorse molecules called heat-shock proteins contribute to refolding proteins that were once misfolded and clumped, causing such disorders as Parkinson's disease, amyotrophic lateral sclerosis, and Alzheimer's disease. Researchers have been developing ways to "reprogram" one such protein – a yeast protein called Hsp104 -- to improve its therapeutic properties.
The Monell Center has received a $1.5M NIH grant to further develop clinical methodology that can predict the path of air flow through a person’s nasal passages. The methodology may someday help physicians predict success taes for surgery to reverse nasal obstruction and associated loss of smell (anosmia).
Despite effective new treatments for their disease, children with pulmonary hypertension (PHT) are still a high-risk group for serious complications and death related to anesthesia and surgery, reports a study in the February issue of Anesthesia & Analgesia.
Maintaining an independent lifestyle is so important for some people as they age that they keep it a secret that they've experienced a fall.
The increase in Medicaid reimbursement for primary care providers, a key provision of the Affordable Care Act (ACA), was associated with a 7.7 percentage points increase in new patient appointment availability without longer wait times, according to results of a new 10-state study — co-authored by researchers at the University of Pennsylvania and the Urban Institute, and funded by the Robert Wood Johnson Foundation — published online-first by the New England Journal of Medicine.
For the first time, researchers at Penn Medicine have found that a mutation in the ATRX gene may serve as a much-needed biomarker for the pheochromocytomas and paragangliomas that become malignant. These rare neuroendocrine tumors are typically benign, but when they go rogue, they become very aggressive.
As the United States population has doubled since 1955, the number of inpatient psychiatric beds in the United States has been cut by nearly 95 percent to just 45,000, a wholly inadequate equation when considering that there are currently 10 million U.S. residents with serious mental illness. A new viewpoint in JAMA looks at the evolution away from inpatient psychiatric beds, evaluates the current system for housing and treating the mentally ill, and then suggests a modern approach to institutionalized mental health care as a solution.
The University of Pennsylvania has announced an expanded relationship with Spark Therapeutics, a late-stage gene therapy company developing treatments for debilitating, genetic diseases. As part of the expanded relationship, which included both an exclusive license agreement to certain Penn-owned intellectual property rights and a clinical trial agreement, Penn will be one of the clinical sites for a clinical trial to evaluate the treatment of a rare genetic form of progressive blindness.
Penn Medicine researchers, in a continuation of their groundbreaking work to better understand how anesthesia works in the body, have found the first new class of novel anesthetics since the 1970s. Their findings, published in February issue of Anesthesiology, detail the processes through which the group uncovered these compounds.
Physicians who use health information technology (HIT) systems are only slightly more likely to receive the patient information they need to provide coordinated care, reports a study in the January issue of Medical Care. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
With many people staring down New Year’s resolutions related to losing weight, some may be wondering if surgical weight loss is right for them. Dr. Ann Rogers, director of Penn State Hershey Surgical Weight Loss, says surgery is only a long-term solution for patients who also resolve to enact some important lifestyle changes.
When retrievable inferior vena cava (IVC) filters were approved for use in the United States in 2003 to prevent pulmonary embolism among patients unable to receive the standard blood thinner treatment, many experts anticipated most of them would be removed when no longer needed and IVC filter complications would decrease. Instead, the number of IVC filters placed has more than doubled in the last 10 years, and by some estimates, less than half of these retrievable devices are actually removed each year.
Lung cancer rates in both smokers and non-smokers are lower in higher-elevation counties in the western part of the United States, suggesting that oxygen may promote the incidence of lung cancer, according to a new study co-authored by a student at the Perelman School of Medicine at the University of Pennsylvania.
Wolters Kluwer announced today that its Lippincott Williams & Wilkins (LWW) medical and nursing journal portfolio won 15 awards in nine categories at the 2014 FOLIO: Eddie & Ozzie Awards. Emergency Medicine News, Oncology Times, and Plastic & Reconstructive Surgery-Global Open all took top spots in their categories. Sponsored by FOLIO: Magazine, the Eddie & Ozzie awards represent one of the industry’s largest, most prestigious awards competitions for magazine and digital editorial and design excellence.
A single layer of metallic nanostructures has been designed, fabricated and tested by a team of Penn State electrical engineers that can provide exceptional capabilities for manipulating light.
Once more, the multifactorial and heterogeneous nature of breast cancer fascinate researchers and is newly confirmed by the results of a study entitled “Anthropometric, metabolic and molecular determinants of human epidermal growth factor receptor 2 expression in luminal b breast cancer”, published in December 2014 in the international journal Journal of Cell Physiology.
Luis J. Montaner—noted HIV/AIDS expert—receives endowed professorship.
Transcatheter aortic valve replacement, or TAVR, has been called one of the biggest advances in cardiac surgery in recent years. The procedure delivers a new, collapsible aortic valve through a catheter to the valve site within the heart - a repair that otherwise requires open heart surgery. While a boon for many patients who would not have been a candidate for conventional surgery, Penn Medicine researchers have discovered that marketing for TAVR does not accurately portray the risks associated with undergoing the procedure. Their analysis is available in the January 12 issue of JAMA Internal Medicine.
Pediatric nurses play a key role in preventing post-traumatic stress in injured children and their families by practicing "trauma-informed care". A new study surveyed pediatric trauma nurses, revealing that they are knowledgeable about practicing trauma-informed care, but need for additional training to help families cope after a child’s injury.
A first-of-its-kind randomized clinical trial from researchers at Penn Medicine and collaborators have shown that the most-suited treatment for each smoker may depend on how quickly they metabolize the nicotine in their body after quitting.
For patients with spinal stenosis, long-term outcomes are comparable with surgery or conservative treatment, reports a study in the January 15 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Effective and efficient healthcare transitions—patient "handoffs" between providers, units, or healthcare systems—are a critical part of efforts to provide coordinated, high-quality patient care. A special focus on Healthcare Transitions is presented in the January/February issue of the Journal for Healthcare Quality (JHQ), the peer-reviewed journal of the National Association for Healthcare Quality (NAHQ). The journal is published by Lippincott Williams & Wilkins (LWW), a part of Wolters Kluwer Health.
New Year’s weight loss resolutions are in full swing, but despite all the hype about the latest wearable tracking devices, there’s little evidence that this technology alone can change behavior and improve health for those that need it most, according to a new online-first viewpoint piece in JAMA. The paper, written by researchers at the University of Pennsylvania, points out that even though several large technology companies are entering this expanding market, there may be a disconnect between the assumed benefits and actual outcomes.
Military service members with mild traumatic brain injury (mTBI), or concussion, should follow a six-step process of progressive activity, leading to return to active duty, according to new clinical recommendations by an expert panel. The guidance appears in the January-February issue of The Journal of Head Trauma Rehabilitation, official journal of the Brain Injury Association of America, an annual special issue devoted to new research on TBI in the military. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
A new collaboration between NCCN and Flatiron Health will provide the opportunity to analyze key quality and outcomes metrics and identify trends and patterns in the care of patients with cancer.
Each year, radon kills more people than home fires, drowning, falls or drunk driving. It is the number one cause of lung cancer in nonsmokers, taking some 21,000 lives annually.
Drexel University’s College of Engineering will honor Ellen Kullman, Chair of the Board and CEO of DuPont, as its 2015 Engineering Leader of the Year. Kullman, who will be recognized at a ceremony on Feb. 23, will join an esteemed group of engineering trailblazers who have received the award.
Even with modern genomewide analysis techniques, it has proven difficult to identify genetic factors affecting risk for depression, according to a topical review in the January issue of Harvard Review of Psychiatry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Jefferson Appoints Sandra Dayaratna, M.D., as Division Director of the Generalist Division of the Obstetrics and Gynecology Department
People exposed to asbestos from mining in Libby, Mont., show long-term changes in lung imaging and function tests, even with relatively low asbestos exposure, reports a study in the January Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).
Adding radiation treatment to hormone therapy saves more lives among older men with locally advanced prostate therapy than hormone therapy alone, according to a new study in the Journal of Clinical Oncology this week from Penn Medicine researchers.
Colder temperatures and less humidity helps the flu virus spread easier among people; so if this winter proves to be a bitter one, it will be especially important to protect yourself.
Because of their responsibility for performing airway intubation and other invasive procedures, anesthesiologists will play an essential role in managing patients with Ebola virus infection. Scientific evidence guiding the anesthetic management of Ebola virus disease (EVD) is presented and analyzed in a special article published by Anesthesia & Analgesia.
By adjusting the levels of a key signaling protein, researchers improved motor function and brain abnormalities in experimental animals with a form of Huntington’s disease, a severe neurodegenerative disorder.
A simple technique may be most effective in preventing heart disease after radiation therapy for breast cancer.
Many patients with type 2 diabetes in the United States may be discouraged from taking metformin—a proven, oral diabetes medicine—because the U.S. Food and Drug Administration inappropriately labels the drug unsafe for some patients also suffering from kidney problems, researchers from Penn Medicine and Weill Cornel Medical College report this week in a research letter published in JAMA Internal Medicine.
An estimated 28,000 lemurs, the world’s most endangered primates, have been illegally kept as pets in urban areas of Madagascar over the past three years, possibly threatening conservation efforts and hastening the extinction of some of lemur species.
The Penn State Hershey Center for the Protection of Children has created an online training module – iLook Out for Child Abuse – to help early child care professionals meet new state laws regarding training and reporting of suspected child abuse. The regulations under Act 31 of 2014 take effect on December 31.
For women who have undergone mastectomy, breast reconstruction using the patient's own tissues—rather than implants—provides higher satisfaction scores, reports a study in the January issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Performed as part of body contouring procedures in patients with massive weight loss, a procedure called medial thigh lift carries a substantial risk of complications, reports a study in the January issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
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