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25-Oct-2019 6:30 AM EDT
33% of people on anticoagulants take over-the-counter supplements with potentially serious interactions
University of California, Los Angeles (UCLA), Health Sciences

Nearly 98% percent of people prescribed direct-acting oral anticoagulants such as apixaban used over-the-counter products. Of those, 33% took at least one such product that, in combination with the anticoagulants, could cause dangerous internal bleeding.

24-Oct-2019 2:30 PM EDT
Cleveland Clinic Study Finds Functional Medicine Model is Associated with Improvements in Health-Related Quality of Life
Cleveland Clinic

In the first retrospective cohort study of the functional medicine model, Cleveland Clinic researchers found that functional medicine was associated with improvements in health-related quality of life. The study was published today in the Journal of the American Medical Association Network Open.

22-Oct-2019 11:05 AM EDT
Antibiotics not necessary for most toothaches, according to new ADA guideline
American Dental Association (ADA)

The American Dental Association (ADA) announced today a new guideline indicating that in most cases, antibiotics are not recommended for toothaches. This guidance, published in the November issue of the Journal of the American Dental Association

Released: 25-Oct-2019 6:30 AM EDT
Lancet Paper Shows Most Popular Hypertension Drug Isn’t Most Effective, Per OHDSI’s LEGEND Study
University of California, Los Angeles (UCLA), Health Sciences

Thiazide diuretics demonstrate better effectiveness and cause fewer side effects than ACE inhibitors as first-line antihypertensive drugs, according to a report published Oct. 24 in The Lancet. Marc A. Suchard, MD, PhD, professor of biostatistics at the UCLA Fielding School of Public Health served as lead author.of the study.

23-Oct-2019 1:05 PM EDT
Most Prescribed Blood Pressure Drugs May Be Less Effective than Others
Columbia University Irving Medical Center

A new study of nearly 5 million patients shows the most-popular first-line treatment for hypertension is less effective and causes more side effects than thiazide diuretics.

Released: 24-Oct-2019 2:45 PM EDT
Controlling the immune system’s brakes to treat cancer, autoimmune disorders
St. Jude Children's Research Hospital

Immunologists at St. Jude Children’s Research Hospital have discovered key biological switches that control regulatory T cells—specialized white blood cells that keep the immune system in check.

Released: 24-Oct-2019 6:05 AM EDT
National Institutes of Health Establishes Center at Lawrence Livermore to Develop Chlamydia Vaccine
Lawrence Livermore National Laboratory

A cooperative research center that aims to develop vaccines for chlamydia has been established by the National Institutes of Health at Lawrence Livermore National Laboratory (LLNL). The center includes two University of California campuses – Irvine and Davis.

21-Oct-2019 3:30 PM EDT
University of Chicago scientists unveil the secret of cancer-associated Warburg effect
University of Chicago Medical Center

A new study, led by researchers at the University of Chicago, provides an answer to why cancer cells consume and use nutrients differently than their healthy counterparts and how that difference contributes to their survival and growth.

23-Oct-2019 8:05 AM EDT
Cleveland Clinic Unveils Top 10 Medical Innovations for 2020
Cleveland Clinic

A dual-acting osteoporosis drug. Minimally invasive mitral valve surgery. New treatment for peanut allergies. These are some of the innovations that will enhance healing and change healthcare in the coming year, according to a distinguished panel of doctors and researchers.

14-Oct-2019 8:00 AM EDT
American Society of Anesthesiologists names Mary Dale Peterson, M.D., FASA, new president
American Society of Anesthesiologists (ASA)

Mary Dale Peterson, M.D., MSCHA, FACHE, FASA, executive vice president and chief operating officer of Driscoll Health System and emeritus staff at Driscoll Children’s Hospital in Corpus Christi

21-Oct-2019 1:30 PM EDT
Clues to improve cancer immunotherapy revealed
Washington University in St. Louis

A new study by researchers at Washington University School of Medicine in St. Louis indicates a way for cancer immunotherapy to spur a more robust immune response. Such knowledge could lead to the development of better cancer vaccines and more effective immunotherapy drugs called checkpoint inhibitors.

Released: 23-Oct-2019 12:05 PM EDT
Northwestern Medicine to Host Five Medication Collection Sites for National Prescription Drug Take Back Day
Northwestern Medicine

Northwestern Medicine is once again coming together with the Drug Enforcement Administration (DEA) to participate in National Prescription Drug Take Back Day with five medication collection sites on Saturday, October 26 from 10 am to 2 pm at locations in Chicago, Winfield, Lake Forest, St. Charles and Sandwich. This DEA initiative provides the community with a safe, convenient and responsible way to dispose of unused opioids and other prescription medications.

Released: 23-Oct-2019 12:00 PM EDT
In Lab, SLU Research Halts Toxic Protein Linked to Muscular Dystrophy
Saint Louis University Medical Center

Researchers are encouraged by the findings, which suggest a way forward in developing the first treatment or cure for facioscapulohumeral muscular dystrophy.

Released: 23-Oct-2019 10:00 AM EDT
Bacterial Lifestyle Steers the Evolution of Antibiotic Resistance
Health Sciences at the University of Pittsburgh

How bacteria live – whether as independent cells or in a communal biofilm – determines the course of their evolution, with implications for drug-resistant infections.

Released: 22-Oct-2019 12:15 PM EDT
How Oncologists Can Ethically Navigate the “Right-to-Try” Drug Law
Perelman School of Medicine at the University of Pennsylvania

The 2018 federal Right to Try Act allows patients with a life-threatening illness to be treated with drugs that have not yet been approved by the Food and Drug Administration (FDA). Many in the oncology community say Right to Try strips away important regulatory protections and view the move as a risky step bound to create ethical dilemmas for physicians whose goal is to guide patients toward safe and appropriate treatment decisions. Oncology is one field at the forefront of requests for unapproved drugs. An interdisciplinary team of bioethicists, oncologists, and lawyers from Penn Medicine and other institutions penned a commentary published online this week in the Journal of Clinical Oncology to offer recommendations to help oncologists navigate this new “Right to Try” world, while maintaining their ethical obligations to patients.

Released: 22-Oct-2019 11:05 AM EDT
PhRMA Foundation Announces New Strategic Mission and Restructured Programs
PhRMA Foundation

The PhRMA Foundation has announced a shift in mission that will focus on building a better system of value assessment in U.S. health care -- empowering patients and improving health outcomes and efficiencies – while helping shape a new era of multidisciplinary research and drug development, based strongly in the use of advanced technology and data.

Released: 22-Oct-2019 8:00 AM EDT
Machine Learning’s Next Frontier: Epigenetic Drug Discovery
Sanford Burnham Prebys

Scientists at Sanford Burnham Prebys Medical Discovery Institute have developed a machine-learning algorithm that gleans information from microscope images—allowing for high-throughput epigenetic drug screens that could unlock new treatments for cancer, heart disease, mental illness and more. The study was published in eLife.

Released: 22-Oct-2019 3:05 AM EDT
Making high-value products from agricultural waste
University of Adelaide

Sunscreen from mushroom waste, healthy skincare products from apples and berries, and high-tech materials from Brussels sprout stalks – these are some high value products that could be first to market from a new $11 million research consortium led by the University of Adelaide.

Released: 21-Oct-2019 11:05 AM EDT
Closures affect 1 in 8 pharmacies in the US
University of Illinois Chicago

From 2009 to 2015 9,654 pharmacies closed. According to new research, independent pharmacies in both urban and rural areas were three times more likely to close than chain pharmacies.

14-Oct-2019 8:05 AM EDT
American Society of Anesthesiologists recognizes Judith Hellman, M.D., with its Excellence in Research Award
American Society of Anesthesiologists (ASA)

The American Society of Anesthesiologists (ASA) today presented Judith Hellman, M.D., with its 2019 Excellence in Research Award in recognition of her outstanding research developments

14-Oct-2019 8:00 AM EDT
American Society of Anesthesiologists recognizes Jerome M. Klafta, M.D., with its Excellence in Education Award
American Society of Anesthesiologists (ASA)

The American Society of Anesthesiologists (ASA) today presented Jerome M. Klafta, M.D., with its 2019 Excellence in Education Award in recognition of his exemplary career as a master clinician and physician educator

14-Oct-2019 8:05 AM EDT
American Society of Anesthesiologists honors Mark A. Warner, M.D., with its Distinguished Service Award
American Society of Anesthesiologists (ASA)

The American Society of Anesthesiologists (ASA) today presented Mark A. Warner, M.D., with its 2018 Distinguished Service Award in recognition of his contributions spanning all areas of the specialty including patient care

14-Oct-2019 8:00 AM EDT
American Society of Anesthesiologists recognizes Seun Johnson-Akeju, M.D.,with its 2019 James E. Cottrell Presidential Scholar Award
American Society of Anesthesiologists (ASA)

The American Society of Anesthesiologists (ASA) today presented Seun Johnson-Akeju, M.D., M.M.Sc., with its 2019 James E. Cottrell Presidential Scholar Award in recognition of his outstanding dedication to the study of neuroscience and anesthesia.

Released: 17-Oct-2019 3:25 PM EDT
A simpler way to make some medicines
Ohio State University

Organic chemists have figured out how to synthesize the most common molecule arrangement in medicine, a scientific discovery that could change the way a number of drugs – including one most commonly used to treat ovarian cancer – are produced. Their discovery, published today in the journal Chem, gives drug makers a crucial building block for creating medicines that, so far, are made with complex processes that result in a lot of waste.

Released: 16-Oct-2019 12:30 PM EDT
Scientists at Wake Forest School of Medicine Identify Genetic Variation Linked to Severity of ALS
Atrium Health Wake Forest Baptist

A discovery made several years ago in a lab researching asthma at Wake Forest School of Medicine may now have implications for the treatment of amyotrophic lateral sclerosis (ALS), a disease with no known cure and only two FDA-approved drugs to treat its progression and severity.

Released: 16-Oct-2019 10:05 AM EDT
UIC College of Pharmacy honored for diversity, inclusion
University of Illinois Chicago

The University of Illinois at Chicago College of Pharmacy has received the 2019 Health Professions Higher Education Excellence in Diversity (HEED) Award from INSIGHT Into Diversity magazine.

Released: 14-Oct-2019 7:05 PM EDT
Drug-light combo could offer control over CAR T-cell therapy
University of California San Diego

UC San Diego bioengineers are a step closer to making CAR T-cell therapy safer, more precise and easy to control. They developed a system that allows them to select where and when CAR T cells get turned on so that they destroy cancer cells without harming normal cells. The system requires two “keys”—the drug Tamoxifen and blue light—to activate CAR T cells to bind to their targets. Just one key keeps the cells inactive.

Released: 14-Oct-2019 1:05 PM EDT
Dementia spreads via connected brain networks
University of California, San Francisco (UCSF)

In a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individual patients with frontotemporal dementia (FTD)

10-Oct-2019 1:30 AM EDT
More Evidence Linking Common Bladder Medication to a Vision-threatening Eye Condition
American Academy of Ophthalmology (AAO)

A drug widely prescribed for a bladder condition for decades now appears to be toxic to the retina, the light-sensing tissue at the back of the eye that allows us to see.

Released: 11-Oct-2019 2:05 PM EDT
Protecting the most vulnerable patients during anesthesia
Morgridge Institute for Research

Pediatric anesthesia is a stressful and critical environment. Dr. Bilen-Rosas wants to help clinicians recognize dangerous sedation pathologies sooner. She teamed up with the Morgridge Fab Lab to create a new medical device that alerts clinicians to compromised airways.

Released: 11-Oct-2019 1:05 PM EDT
New Opioid Prescription Dosages Drop 22 Percent in Penn Medicine’s New Jersey Practices Following Changes to State Law and Health Record Alerts
Perelman School of Medicine at the University of Pennsylvania

The total amount of opioids dispensed per new opioid prescription decreased by 22 percent in Penn Medicine outpatient practices in New Jersey after the state passed a law limiting prescriptions to a five-day supply for new opioid prescriptions. Penn Medicine implemented an electronic health record (EMR) alert, or “nudge,” to notify clinicians if that limit had been reached. The study, published online today in the Journal of General Internal Medicine, is one of the first evaluations of a state law’s impact on prescribing outcomes, and is the first report of an EMR being used to make compliance with prescribing limits easier. Importantly, after the prescribing limit and alert went into effect there was no evidence to suggest pain control worsened.

Released: 11-Oct-2019 10:00 AM EDT
AACC’s Journals, Clinical Chemistry and The Journal of Applied Laboratory Medicine, to Be Published through Oxford University Press
Association for Diagnostic and Laboratory Medicine (ADLM (formerly AACC))

AACC, a global scientific and medical professional organization dedicated to better health through laboratory medicine, is pleased to announce a publishing partnership with Oxford University Press for its peer-reviewed journals, Clinical Chemistry and The Journal of Applied Laboratory Medicine. Both journals will join Oxford University Press’s world-class science portfolio starting in January 2020. The partnership will increase researchers’ and healthcare practitioners’ access worldwide to the important science published in the journals.

8-Oct-2019 4:00 PM EDT
CF Patients Experience Improved Lung Health with Lumacaftor-Ivacaftor But with Caveats
American Thoracic Society (ATS)

In adolescent and adult patients with cystic fibrosis taking lumacaftor-ivacaftor (ORKAMBI®), the combination drug appears to improve lung function and body weight and reduce the need for intravenous antibiotic treatment, according to a French study published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

Released: 10-Oct-2019 2:05 PM EDT
UC San Diego’s Center for Medicinal Cannabis Research Awards Grants for Five Novel Studies
UC San Diego Health

The Center for Medicinal Cannabis Research at University of California San Diego School of Medicine announces $3 million in research grants to explore new applications of cannabis for a number of novel medical applications.

Released: 10-Oct-2019 7:05 AM EDT
Research to Prevent Blindness Grantee Dr. Gregg Semenza Wins Nobel Prize in Medicine
Research to Prevent Blindness

Research to Prevent Blindness (RPB) is pleased to announce that RPB Stein Innovation Awardee Gregg Semenza, MD, PhD, at Johns Hopkins University School of Medicine, has been named a winner of the 2019 Nobel Prize in Medicine.

Released: 9-Oct-2019 10:30 PM EDT
Men Receiving Opioids After Vasectomy at High Risk for Persistent Opioid Use
Wolters Kluwer Health

Routine use of opioids after vasectomy doesn't improve pain control, but is associated with a substantial rate of persistent opioid use in the months after the procedure, reports a study in the October issue of The Journal of Urology®, Official Journal of the American Urological Association (AUA). The Journal is published in the Lippincott portfolio by Wolters Kluwer.

Released: 8-Oct-2019 12:05 PM EDT
Psychedelic Drug to Be Tested for Treatment-Resistant Depression in Houston
University of Texas Health Science Center at Houston

Psilocybin, a psychedelic drug believed to help rewire the brain, is now being studied to relieve treatment-resistant depression at The University of Texas Health Science Center at Houston (UTHealth) as part of a global Phase II clinical trial.

Released: 7-Oct-2019 1:05 PM EDT
Antipsychotics linked to accumulation of hospital days in persons with Alzheimer's disease
University of Eastern Finland

People with Alzheimer's disease who used antipsychotic drugs had a higher number of accumulated hospital days than people with Alzheimer's disease who did not use antipsychotics

Released: 7-Oct-2019 11:40 AM EDT
Researchers land funding to help launch diabetic ulcer drug over ‘Valley of Death’
University of Notre Dame

Notre Dame's $4.6 million award from the Department of Defense will help fund the expensive studies required before the compound can be given approval by the FDA to be tested on people.

Released: 7-Oct-2019 11:05 AM EDT
Number of depressed over-65s unchanged but antidepressant use soars
University of East Anglia

The proportion of people aged over 65 on antidepressants has more than doubled in two decades - according to new research led by the University of East Anglia.

   
4-Oct-2019 4:30 PM EDT
Treating Pulmonary Embolism: How Safe and Effective Are New Devices?
Perelman School of Medicine at the University of Pennsylvania

A new scientific statement from the American Heart Association identifies the risks and benefits of using novel interventional devices compared to anticoagulation alone to treat patients with pulmonary embolism.

1-Oct-2019 10:45 AM EDT
New Study Discovers the Three-Dimensional Structure of the Genome Replication Machine
Mount Sinai Health System

Mount Sinai researchers have discovered how the enzyme DNA polymerase delta works to duplicate the genome that cells hand down from one generation to the next.

   
Released: 3-Oct-2019 10:15 AM EDT
Dr. Ralph Buschbacher Recognized for Innovation in Nerve Conduction Studies
American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM)

Due to his innovations in the field of electrodiagnostic medicine, Dr. Buschbacher has been nominated for this year’s American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) Innovation Award.



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