Recovery of blinking function is a critical but easily overlooked outcome after facial transplantation, according to a report in the January issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Elyse Hoffmann promoted to Wistar director of donor relations and special events.
Recent guidelines seeking to reduce the use of neuroimaging tests for patients with headaches run the risk of missing or delaying the diagnosis of brain tumors, according to a special article in the January issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
A recent report provided anesthesiologists with reassuring data on the safety of caudal nerve block—sometimes called the "kiddie caudal"—for infants and young children undergoing surgery. But an editorial in the January issue of Anesthesia & Analgesia draws attention to some important limitations of the study and to the need for further research on the safety and efficacy of this widely used pediatric anesthesia technique.
Just like holly wreaths, twinkling lights, Santa Claus, flying red-nosed reindeer and decorated evergreen trees, myths and superstitions have become part of our holiday lore. A Temple University psychologist offers the truth behind some of these false holiday beliefs.
New findings show how an inactivating polymorphism in the TLR5 Gene that occurs in more than one out of 15 people, plays important role in progression of luminal breast cancer and ovarian cancer
Russel E. Kaufman steps down as the Wistar Institute President & CEO and Dario C. Altieri, Wistar Cancer Center Director, named new CEO.
Type 1 diabetes (T1D) patients who have developed low blood sugar (hypoglycemia) as a complication of insulin treatments over time are able to regain normal internal recognition of the condition after receiving pancreatic islet cell transplantation, according to a new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania, published online in Diabetes.
The cause of prostate cancer may be linked to Parkinson’s disease through a common enzyme family called sirtuins.
Cigarettes have been convicted of many crimes over the years. But the jury's still out on whether their younger, more fashionable cousins – electronic cigarettes, or e-cigarettes – will meet the same fate.
Researchers gain new insight into how motor neurons in the brain die during ALS
Jason H. Moore, PhD, has been named the first permanent director of the Penn Institute for Biomedical Informatics (IBI), at the Perelman School of Medicine at the University of Pennsylvania. His appointment starts March 1, 2015. Moore is an expert in genetics and biomedical informatics, who is currently on faculty at Dartmouth College.
Researchers have discovered a way to repurpose fibroblasts into functional melanocytes, the body's pigment-producing cells. The technique has immediate and important implications for developing new cell-based treatments for skin diseases such as vitiligo, as well as new screening strategies for melanoma.
The Fatherhood Research and Practice Network, a collaboration between Temple University and Denver’s Center for Policy Research, has awarded $350,000 to four projects that will evaluate fatherhood programs in order to determine how to best serve low-income fathers.
All children should undergo vision health screening between age 36 and 72 months—preferably every year—using evidence-based test methods and with effective referral and follow-up, according to recommendations published in the January issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
While many Americans are open to compensating college athletes in some form, more Americans prefer to see colleges continue to treat athletes as amateurs who compete primarily for love of the sport and educational opportunities, not for pay. That’s according to a new national survey by the Saint Leo University Polling Institute
Frequent kidney dialysis can cause systemic inflammation, leading to complications such as cardiovascular disease and anemia by triggering the complement cascade, part of the innate immune system. Complement is inadvertently activated by modern polymer-based dialysis blood filters. New work has found an effective way to avoid these problems by temporarily suppressing complement during dialysis.
Wolters Kluwer Health is pleased to announce that, Retinal Cases & Brief Reports, a publication dedicated to publishing peer-reviewed case reports and brief reports in the diagnosis and treatment of retinal and vitreous diseases, has been accepted for indexing by MEDLINE/PubMed and Scopus. All articles back to Volume 1 Issue 1 now appear in PubMed and going forward all articles will be indexed immediately upon publication.
In a newly published study, Paul Lieberman and his lab report how this aggressive virus known for cold sores can manipulate the protective ends of our chromosomes to replicate and spread.
The Ebola virus travels from person to person through direct contact with infected body fluids. But how long can the virus survive on glass surfaces or countertops? How long can it live in wastewater when liquid wastes from a patient end up in the sewage system? In an article published Dec. 9 in the journal Environmental Science & Technology Letters, researchers from the University of Pittsburgh and Drexel University plot a course for future study of the virus.
Today marks the 20th anniversary of the first (contemporary) Russian invasion of Chechnya. While made by the Yeltsin administration, that decision has had an enormous impact on current Russian identity and now President Vladimir Putin's power. Moreover, this strategy of two decades ago has a familiar ring: promote popular approval during hard times by turning to violence against some undesirable “other” — Chechen terrorists in 1994 and Ukrainian fascists today.
Hospitals with robotic surgical systems are more likely to perform "nephron-sparing" partial nephrectomy—a recommended alternative to removal of the entire kidney—in patients with kidney cancer, reports a study in the December issue of Medical Care. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
While the holidays are a time of merriment and festivities for many, some people struggle with depression during this time of year. Dr. Erika Saunders, interim chair of psychiatry at Penn State Hershey, says there are some distinct warning signs to watch for.
Two-thirds of women treated for early-stage breast cancer in the U.S. receive longer radiation therapy than necessary, according to a new study published in JAMA this week from Penn Medicine researchers Ezekiel J. Emanuel, MD, PhD, and Justin E. Bekelman, MD.
Home Healthcare Now: The Interprofessional Journal for Home Care and Hospice Clinicians announced today a relaunch of the publication. Formerly known as Home Healthcare Nurse, the new name and direction of the journal reflects today’s interprofessional approach to practical clinical care. Home Healthcare Now is the official publication of the Visiting Nurse Association of America, and is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Terri Erbacher, a school psychologist at Philadelphia College of Osteopathic Medicine, and colleagues' new book addresses all aspects of suicide prevention and intervention.
In the first year after the Accreditation Council for Graduate Medical Education (ACGME) reduced the number of continuous hours that residents can work, there was no change in the rate of death or readmission among hospitalized Medicare patients, according to a new study published in JAMA. The study was led by researchers at the Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia.
Researchers at Penn Medicine, in collaboration with a multi-center international team, have shown that a protease inhibitor, simeprevir, a once a day pill, along with interferon and ribavirin has proven as effective in treating chronic Hepatitis C virus infection (HCV) as telaprevir with interferon and ribavirin, the standard of care in developing countries. Further, simeprevir proved to be simpler for patients and had fewer adverse events. The complete study is now available online and is scheduled to publish in January 2015 in The Lancet Infectious Diseases.
E-cigarettes appear to be less addictive than cigarettes in former smokers and this could help improve understanding of how various nicotine delivery devices lead to dependence, according to researchers.
Within a few months after drug withdrawal, patients in recovery from dependence on prescription pain medications may show signs that the body's natural reward systems are normalizing, reports a study in the Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
The promise of a new year sparks the desire to get healthy – a goal Karin Richards, chair of the kinesiology program at University of the Sciences, says should begin with a physical exam at the doctor’s office.
What is the impact on expectant mothers and hospitals when there are large-scale closures of maternity units? A new study provides views from hospital staff members in Philadelphia, where 13 out of 19 obstetric units closed in a 15-year period.
This study is first ever comprehensive analysis to investigate the Affordable Care Act’s ( Essential Health Benefit (EHB) as it relates to children. The study found that the EHB has resulted in a state-by-state patchwork of coverage for children and adolescents that has significant exclusions, particularly for children with developmental disabilities and other special health care needs.
The latest results of clinical trials of more than 125 patients testing an investigational personalized cellular therapy known as CTL019 will be presented by a University of Pennsylvania research team at the 56th American Society of Hematology Annual Meeting and Exposition. Highlights of the new trial results will include a response rate of more than 90 percent among pediatric acute lymphoblastic leukemia patients, and results from the first lymphoma trials testing the approach, including a 100 percent response rate among follicular lymphoma patients and 45 percent response rate among those with diffuse large B-cell lymphoma.
An innovative therapy against a highly aggressive leukemia continues to show highly promising results in children treated in a pilot study. Of 39 children receiving bioengineered T cells, 92 percent had no evidence of cancer a month after treatment.
Wistar's Ken-ichi Noma, Ph.D., wins the W.W. Smith Charitable Trust grant.
People with mental illness are more likely to have been tested for HIV than those without mental illness, according to a new study from a team of researchers at Penn Medicine and the U.S. Centers for Disease Control and Prevention (CDC) published online this week in AIDS Patient Care and STDs. The researchers also found that the most seriously ill – those with schizophrenia and bipolar disease – had the highest rate of HIV testing.
The NCCN 3D Virtual Simulator Learning Platform allows users to walk through the continuum of care approach to colorectal cancer in a risk-free environment with increasingly complex clinical presentations.
Joy and goodwill aren’t the only things we start spreading to friends, family, colleagues -- even strangers -- this time of year. Late fall and early winter also signal the start of annual spread of the influenza virus.
Scientists at Penn State College of Medicine, working alongside an international team of researchers, have produced the most complete encyclopedia of functional elements in the mouse genome to date and compared it to the human genome. The findings, published recently in Nature, uphold the mouse model of human disease, but pinpoint important differences in gene expression that will guide future health research.
Quitting smoking sets off a series of changes in the brain that Penn Medicine researchers say may better identify smokers who will start smoking again—a prediction that goes above and beyond today’s clinical or behavioral tools for assessing relapse risk.
Chronic kidney disease affects at least one in four Americans who are older than 60 and can significantly shorten lifespan. Yet the few available drugs for CKD can only modestly delay the disease’s progress towards kidney failure. Now, a team has found an aspect of CKD’s development that points to a promising new therapeutic strategy.
Wistar and Penn scientific alliance, which has worked together for past 16 years, was announced as winners by GlaxoSmithKline of the 2014 Discovery Fast Track Challenge.
Chronic kidney disease (CKD) affects at least one in four Americans who are older than 60 and can significantly shorten lifespan. Yet the few available drugs for CKD can only modestly delay the disease’s progress towards kidney failure. Now, a team has found an aspect of CKD’s development that points to a promising new therapeutic strategy.
The health departments of the nation's largest cities play a central role in developing innovative population health strategies for improving public health across the United States, according to a special January issue of the Journal of Public Health Management and Practice. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
French neurosurgeon Alim Louis Benabid and American neurologist Mahlon DeLong were recently named winners of the 2014 Lasker-DeBakey Clinical Medical Research Award for their roles in developing deep brain stimulation (DBS) for the treatment of Parkinson disease. The December issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, includes a special tribute to Dr. Benabid, the first neurosurgeon to receive this prestigious award. Neurosurgery is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
A study using intricate fiber dissection techniques provides new insights into the deep anatomy of the human brainstem—and helps to define "safe entry zones" for neurosurgeons performing brainstem surgery, according to a special article published in Operative Neurosurgery, a quarterly supplement to Neurosurgery, official journal of the Congress of Neurological Surgeons. These publications are published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Remember that holiday song "Grandma Got Run Over by a Reindeer"? It begs the question "Is Santa and his team of reindeer guilty of running over Grandma?" Medical sleuths investigate and provide their expert opinion on what really happened.
The receptor CCR5, targeted by HIV drugs, is also key in driving prostate cancer metastases, suggesting that blocking this molecule could slow prostate cancer spread
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