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Viruses often mutate or hide themselves within cells. But by mimicking the way the immune system naturally deals with invaders, researchers reporting in ACS Infectious Diseases have developed a “peptoid” antiviral therapy that effectively inactivates three viruses in lab tests.
Which types of personalities were more hesitant about COVID-19 vaccination during the pandemic’s peak? Extroverts — according to a new study on more than 40,000 Canadians.
Even vulnerable people, who are at risk of severe Covid-19, achieved good antibody levels after three doses of mRNA vaccine.
The availability, speed and effectiveness of genomic sequencing increased dramatically during the pandemic, as scientists worldwide rushed to find ways to track and predict the virus’s movement and evolution. It also was critical in the development of effective vaccines. In an essay published today, two NAU biologists argue that building on this momentum is critical in society’s response to future pandemics, but it requires significant collaboration and investment now, before the next pathogen is threatening society.
The coronavirus pandemic is no longer a national emergency, but the virus that causes COVID-19 isn’t gone—and neither is the risk of getting the disease. For parents, navigating when to get their child vaccinated and knowing how to best protect their child from COVID-19 can be complicated. We spoke to Michael Smit, MD, MSPH, Hospital Epidemiologist and Medical Director of Infection Prevention and Control at Children’s Hospital Los Angeles, to get an update on the latest COVID-19 vaccine information and precautions.
Two clinical trials that will evaluate drugs, biologics, medical devices, and other therapies for long COVID that are sponsored by the National Institutes of Health (NIH) will launch at UTHealth Houston.
Today, the National Institutes of Health launched and is opening enrollment for phase 2 clinical trials that will evaluate at least four potential treatments for long COVID, with additional clinical trials to test at least seven more treatments expected in the coming months. Treatments will include drugs, biologics, medical devices and other therapies.
A mammalian protein previously shown by UT Southwestern microbiologists to inhibit the virus that causes COVID-19 in cell culture also protected live mouse models, significantly limiting infection in the lung cells and diminishing the symptoms. The findings, published in Nature Microbiology, could lead to new strategies to treat COVID-19, which still infects thousands and kills hundreds in the U.S. every week.
Scientists at St. Jude Children’s Research Hospital showed that fixed mutations within a viral population most likely stem from how easy it is to acquire that mutation (i.e., mutation accessibility) rather than just its benefit.
A metabolic by-product that is more prevalent during fasting may supercharge immune cells as they fight infection and disease, reports an early stage study by Van Andel Institute scientists and collaborators.
UC San Diego scientists debut Greengenes2, a massive reference database that could be used to reconcile years of microbiome studies.
Support for early career researchers is about to get a major boost, thanks to a new fellowship fund established by leaders at La Jolla Institute for Immunology (LJI) and Japan-based global pharmaceutical corporation, Kyowa Kirin, Inc.
The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its new variants has created a need for effective disinfection technologies to protect against harmful pathogens. While vaccines offer some protection, their effectiveness against future variants is uncertain. Therefore, additional strategies are important during the pre-vaccine stage.
Programmed cell death, a fundamental biological process that facilitates the elimination of old, damaged, infected, and non-functional cells, plays a crucial role in maintaining the balance between health and disease in the human body.
In a new study, scientists at La Jolla Institute for Immunology (LJI) compared the immune response of individuals who received older versus newer versions of the whooping cough vaccine. The unexpected findings may help explain the recent rise in whooping cough cases and point to potential targets for the next generation of vaccines.
Researchers have found that dozens of viruses respond to quorum sensing or other chemical signals from bacteria.
Hip replacement surgery is safe for patients living with human immunodeficiency virus (HIV), researchers at UT Southwestern Medical Center found.
Cancer patients saw a significant fall in Covid-related hospitalisations and mortality following the rollout of vaccines in the first panoramic study of its kind.
A new paper in Biology Methods & Protocols, published by Oxford University Press, shows it may be possible to design vaccines that will induce a stronger immune response to infecting pathogens, such as the virus causing COVID-19.
Self-collected tests performed similarly to provider-collected tests for detecting common sexually transmitted infections (STIs), according to research presented today at the 2023 AACC Annual Scientific Meeting & Clinical Lab Expo.
Today, at the 2023 AACC Annual Scientific Meeting & Clinical Lab Expo, scientists will present new data about rates of co-infections with SARS-CoV-2, influenza, and respiratory syncytial virus (RSV) in the United States.
An analysis of real-world data from more than 1.2 million patients from health systems in four geographically dispersed states -- Indiana, Oregon, Texas and Utah -- conducted by the U.S. Centers for Disease Control and Prevention’s VISION Network, has determined both the number of adults needed to be vaccinated to prevent one COVID-19 associated hospitalization and the number needed to be vaccinated to prevent one COVID-19 associated emergency department (ED) visit.
Although infections can present with many different symptoms, one common symptom is the loss of fat and muscle, a process called wasting.
NIH's RADx Tech committed resources in early 2022 for increased accessibility of COVID-19 home tests. The RADx Tech Accessibility Program subsequently invited collaboration from advocacy organizations to contribute to design insights and is a first step that will help manufacturers address the gap in accessible test availability.
A team of researchers led by Rensselaer Polytechnic Institute’s Jonathan S. Dordick, Ph.D., Institute Professor of Chemical and Biological Engineering, has illuminated a new possibility for the treatment and prevention of COVID-19 in research published in Communications Biology.
While the incidence of influenza-associated neuropsychiatric events in children in the United States is unknown, the controversy over the use of a common antiviral medication typically administered to treat flu in children has sparked concern among parents and medical professionals alike. The dilemma about whether the treatment causes neuropsychiatric events or if the infection itself is the culprit, led a group of pediatric researchers at Monroe Carell Jr.
When people who publicly reject COVID-19 vaccines later die from the disease, observers have complex reactions to their fates, a new study suggests. While very few rejoice in the deaths of anti-vaxxers, some people believe those who are dogmatic against vaccines are deserving of worse outcomes – and that reaction is related to the political party affiliation and vaccination status of the person evaluating the anti-vaxxer.
Researchers have created a resource for analyzing how viruses infect human cells. The fruit fly-based toolkit provides a shortcut for assessing SARS-CoV-2 genes and understanding how they interact with human proteins, offering researchers a resource for new COVID-related drug therapies.
An interdisciplinary research team from Bochum, Duisburg and Zurich has developed a new approach to construct modular optical sensors which are capable of detecting viruses and bacteria.
UK researchers have found that people with longer-term COVID-19 symptoms including brain fog showed reduced performance in tasks testing different mental processes up to two years after infection with the virus.
Developed by OnsiteGene Inc. and sponsored by the NIH RADx initiative, PeakV is a sample-to-answer instrument that transforms PCR testing.
The Icahn School of Medicine at Mount Sinai in New York, NY is pleased to announce that CastleVax, Inc. has completed enrollment and a preliminary analysis of a phase 1 trial of its licensed Newcastle disease virus (NDV)-based COVID-19 booster vaccine.
The July 2023 issue of SLAS Discovery, the open access journal focused on research progressing drug discovery, is now available.
Rather than turn to vices such as alcohol and drugs, many people turned to new pursuits to cope with pandemic-related stresses, according to a Rutgers study.
Women with Lyme disease take longer to get diagnosed, have more severe symptoms and experience higher rates of disability when compared to men.
Scientists have long used community advisory boards to engage communities and provide feedback on studies, but this model has limitations. Now, Wistar Institute researchers are sharing how a more inclusive model for community engagement can lead to deeper insights and greater community participation in HIV research.
People who contract COVID-19 but never develop symptoms – the so-called super dodgers – may have a genetic ace up their sleeve. They’re more than twice as likely as those who become symptomatic to carry a specific gene variation that helps them obliterate the virus, according to a new study led by UC San Francisco researchers.
Scent dogs may represent a cheaper, faster and more effective way to detect COVID-19, and could be a key tool in future pandemics, a new review of recent research suggests.
The fight against dengue fever has a new weapon: a mosquito infected with the bacteria Wolbachia, which prevents the spread of the virus. These mosquitoes have now been deployed in several trials demonstrating their potential in preventing disease transmission.
BU research highlights how healthcare inequities between urban and rural areas, and vaccine skepticism, played a role in deaths related to COVID.
The COVID-19 pandemic hit the educational systems. It is estimated that approximately 1.6 billion children worldwide were affected by school closures, which had a major impact on their learning.
Researchers have cracked how a particular type of immune cell develops in the body and protects against infection and disease. And the discovery could help in the development of more preventive treatments, according to a new study.
Bioengineers have found a way to program the size and shape of virus particles by combining viral protein building blocks and templates made from DNA. The resulting nanostructures could have applications in vaccine development and transporting drugs inside the body.
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