Case Western Reserve University ‘groundbreaking’ study shows exposure to domestic violence carries long-term consequences for both children and society
A program designed to help coaches learn to identify and report suspected child abuse and neglect among their players has measurable impact 10 months later, a new study shows.
It might seem surprising that a colony of ants would tolerate the type of guests that gobble both their grub and their babies. But new research shows there’s likely a useful tradeoff to calmly accepting these parasite ants into the fold: They have weaponry that’s effective against their host ants and a more menacing intruder ant.
You can wear an exoskeleton, but it won’t turn you into a superhero. In the journal Applied Ergonomics, researchers report that that a commercially available exoskeleton relieved stress on the arms just as it was supposed to—but it increased stress on the back by more than 50 percent.
Both civilians and military veterans with post-traumatic stress disorder (PTSD) reap long-term benefits from psychotherapies used for short-term treatment, according to a new study from Case Western Reserve University.
In a qualitative study, researchers focused on Cleveland service providers who shared how foreclosure affects their clients. The research was recently published in The Journal of Contemporary Social Services.
Ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) alone or in combination with acetaminophen are better at easing dental pain than opioids, according to new research conducted with the School of Dental Medicine at Case Western Reserve University.
Despite universal newborn screening that detects the presence of sickle cell trait (SCT), only 16 percent of Americans with SCT know their status. To address this issue, in Ohio, in-person education is offered to caregivers of referred infants with SCT.
Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in children. Scientists report in the journal Molecular Cancer Therapeutics testing the small molecule 6-thio-2’deoxyguanosine (6-thio-dG) in brain cancer stem cells derived from tumor cells donated by patients. Researchers also tested the treatment in humanized mouse models of pediatric brain cancer.
A landmark 2016 Cleveland Clinic study of widely used pain-relieving drugs showed that celecoxib (Celebrex) was associated with comparable cardiovascular safety and better gastrointestinal and kidney safety when compared with either naproxen (Naprosyn) and ibuprofen (Motrin).
A new substudy, published today in the Journal of the American College of Cardiology, analyzed outcomes in PRECISION based on the presence or absence of aspirin use with specific NSAIDs (nonsteroidal anti-inflammatory drugs).
A study by scientists at Cincinnati Children’s reports that the Epstein-Barr virus (EBV)—best known for causing mononucleosis—also increases the risks for some people of developing seven other major diseases. Published in Nature Genetics, researchers report EBV also plays a role in six other diseases: multiple sclerosis, rheumatoid arthritis, inflammatory bowel disease, type 1 diabetes, juvenile idiopathic arthritis, and celiac disease.
Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure. Researchers at the Cincinnati Children’s Heart Institute report in the journal Circulation
Across the world, over 200 million cases of malaria and nearly 500,000 deaths from the disease occur annually—more than 90 percent of which happen in Africa. Children in Africa can be diagnosed with malaria two or three times a year, a rate that decreases as they become older and develop immunity. But the way children generate and maintain this immunity remains a mystery. Katherine Dobbs, MD, a tropical infectious diseases and malaria researcher, is conducting research in Kenya to find answers by studying white blood cells important to innate immunity, the body’s “first response” to infection.
New research from The Ohio State University offers a glimpse into the complexity of interactions between bacteria and the viruses – or phages – that infect them.
Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclinical laboratory tests. Researchers at Cincinnati Children’s Hospital Medical Center report their data in the journal Cell Reports. Studying mice with IPF and donated human cells, they identified a gene called FOXF1 that inhibits the IPF disease.
Researchers from Case Western Reserve University School of Medicine and colleagues have discovered how two brain regions work together to maintain attention, and how discordance between the regions could lead to attention deficit disorders, including schizophrenia, bipolar disorder, and major depression.
A blood test may have the potential to speed accurate diagnosis – and proper treatment – of bipolar disorder in children, new research suggests. Researchers found that children with bipolar disorder had higher blood levels of a protein associated with vitamin D compared to children without mood disorders.
The Ohio State University Wexner Medical Center will establish the nation’s first center dedicated to treating those with heart failure and arrhythmia with gifts totaling $18 million from Bob and Corrine Frick, who have been shadowed by heart disease for generations.
Men on hormone therapy for prostate cancer may benefit significantly from hitting the gym with fellow patients and choosing more veggies and fewer cheeseburgers, a new study suggests.
Rear-facing car seats have been shown to significantly reduce infant and toddler fatalities and injuries in frontal and side-impact crashes, but they’re rarely discussed in terms of rear-impact collisions. Since rear-impact crashes account for more than 25 percent of all accidents, researchers at The Ohio State University Wexner Medical Center conducted a new study to explore the effectiveness of rear-facing car seats in this scenario.
One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works to influence the immune system, new research suggests.
Leading cancer researchers, Alex Huang MD, PhD, and Yamilet Huerta, MD have been awarded $186,405 in grants from the St. Baldrick’s Foundation to conduct pediatric cancer research.
Steven J. Allen, MD, MBA, Nationwide Children's Hospital CEO, announced his plans for retirement today, effective June 30, 2019. Allen, who will be 67 when he retires, has served since 2006, guiding Nationwide Children's Hospital through the most significant period of growth in its 126-year history. Allen will continue as CEO through the search for his successor and beyond as Emeritus Executive for Nationwide Children's Hospital following his retirement.
Narcissists aren’t necessarily on the hunt for partners who are already in a relationship – but that doesn’t appear to stand in their way, either, new research suggests.
Head and neck cancers (squamous cell carcinomas or HNSCC) represent more than half-a-million cases and 300,000 deaths a year, making them the sixth-leading cancer worldwide, according to the World Health Organization.
A Case Western Reserve University-led research team will analyze computerized images of tissue samples for patterns which could become "biomarkers," or predictors, for determining relative risk for recurrence in one particularly common type of head and neck cancers.
We tend to think of heroes in terms of a psychological profile: brave, altruistic, strong.But a new study suggests that for at least one kind of heroism, it takes a village to save a life.
A Case Western Reserve University School of Medicine researcher has compiled evidence from more than 100 publications to show how obesity increases risk of 13 different cancers in young adults. The meta-analysis describes how obesity has shifted certain cancers to younger age groups, and intensified cellular mechanisms promoting the diseases.
A survey of Ohioans, conducted by Baldwin Wallace University’s Community Research Institute (CRI), found broad support for new measures to regulate the sale of firearms with three quarters of registered voters in favor of raising the minimum age to buy semiautomatic rifles to 21 and establishing mandatory waiting periods to purchase a gun.
A survey of Ohioans, conducted by Baldwin Wallace University’s Community Research Institute (CRI), found broad support for new measures to regulate the sale of firearms with three quarters of registered voters in favor of raising the minimum age to buy semiautomatic rifles to 21 and establishing mandatory waiting periods to purchase a gun.
A few months into her pregnancy, Anisah Brown had a routine ultrasound that detected a large hole in her baby’s diaphragm. Her baby had been diagnosed with a congenital diaphragmatic hernia, or CDH. The hole would let the liver, stomach and other internal organs compress the lungs, leaving them little room to develop. Her doctor told her there was no hope. But that was before she came to the Cincinnati Fetal Center.
Stellar grades in college could hurt – rather than help – women new to the job market, according to a new study that suggests employers place more value on the perceived “likability” of female applicants than on their academic success.
University Hospitals Harrington Heart & Vascular Institute officially opened the APOLLO trial today implanting the Intrepid transcatheter mitral valve replacement system on the first patient involved in the study.
Drs. Alan Markowitz and Guilherme F. Attizzani performed the first procedure in the state of Ohio.
Researchers at Cincinnati Children’s report in the journal Pediatrics a link between parents impacted by adverse childhood experiences and increased risk for delayed development of their children at age two.
While Americans debate the rising cost of health care, a new study of 30 countries over 27 years found that medical expansion has improved overall health – with one major exception. Researchers found that increased spending on health care and increases in specialized care were both associated with longer life expectancy and less mortality in the countries studied. But pharmaceutical industry expansion was linked to negative health effects.
Researchers at Case Western Reserve University have cracked the evolutionary mystery of why chimpanzees and gorillas walk on their knuckles: The short explanation is that these African apes climb trees and they are mobile on the ground.
Case Western Reserve University School of Medicine is ranked #25 of all research-oriented medical schools in the nation and #1 in Ohio, according to the annual ranking of graduate schools released today by U.S. News & World Report.
“This recognition is testimony to the outstanding quality of our faculty and students,” said Pamela B. Davis, MD, PhD, dean of Case Western Reserve University School of Medicine and the university’s senior vice president for medical affairs. “Our placement among the top 25 medical schools in the United States and as number one in Ohio reflects our commitment to excellence in medical education and research.”
The rankings are based on two general factors: 1) statistical criteria such as amount of research funding obtained by faculty members, faculty-to-student ratios, and measurable qualifications of admitted students, such as Medical College Admission Test scores; and 2) peer assessments from medical and osteopathic school deans nationally, deans of ac
Our faces broadcast our feelings in living color—even when we don’t move a muscle. That’s the conclusion of a groundbreaking study into human expressions of emotion, which found that people are able to correctly identify other people’s feelings up to 75 percent of the time—based solely on subtle shifts in blood flow color around the nose, eyebrows, cheeks or chin.
Announcement of the fifth annual Harrington Prize for Innovation in Medicine being awarded to Helen H. Hobbs, MD, investigator of the Howard Hughes Medical Institute and Professor of Internal Medicine and Molecular Genetics at the University of Texas Southwestern Medical Center.
Children with mild to moderate asthma do not benefit from a common practice of increasing their inhaled steroids at the first signs of an asthma exacerbation, according to clinical trial results published in The New England Journal of Medicine. Researchers found short-term increases in inhaled steroids did not prevent attacks in children aged 5 to 11, and may even slow a child’s growth.
An Ohio integrated health system and a national social enterprise have announced a new alliance to mobilize tens of millions of dollars for underinvested communities—starting with a $45 million effort to scale up economic opportunity and improve health outcomes in Toledo and the surrounding region over the next decade.
The Cincinnati Drug and Poison Information Center at Cincinnati Children's is seeing an increasing number of calls regarding drug overdoses as the nation copes with the opioid epidemic.
In a study that has implications for humans with inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six-week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn’s-like disease, but had no substantive effect on those without the condition. Crohn's disease is an inflammatory bowel disease of the digestive tract, which can lead to abdominal pain, severe diarrhea, bloody stools, weight loss, and fatigue. About 10-15 percent of human patients report that sweeteners worsen their disease.
A team of researchers led by Cleveland Clinic has published first-of-its-kind findings in Science Translational Medicine on a new method of restoring natural movement sensation in patients with prosthetic arms.
Led by Paul Marasco, Ph.D., the research team has successfully engineered a sense of complex hand movement in patients with upper limb amputations.
New research from Case Western Reserve University has experts re-thinking what was previously believed about the patterns of serial rapists—that they don’t stick with the same modus operandi.
Dr. Bruce Collet, associate professor at Bowling Green State University School, sees the important role public schools have in acculturating immigrants into their new societies. In his new book, "Migration, Religion, and Schooling in Liberal Democratic States" (Routledge, 2018) he lays out recommendations on how these institutions can help facilitate immigrants' integration.