Scientists at the U-M Medical School have discovered the biological equivalent of a grocery store bar code on the surface of primitive, blood-forming stem cells. Called hematopoietic stem cells, they give rise to all the different types of specialized cells in blood.
According to research published today, investigators have used new techniques in the laboratory that allowed them for the first time to derive unlimited numbers of purified mesenchymal precursor cells from human embryonic stem cells.
Heart specialists at Johns Hopkins believe they have figured a way around a persistent barrier to successful adult stem cell therapy for millions of Americans who have survived a heart attack but remain at risk of dying from chronic heart failure.
Researchers at Wake Forest University School of Medicine have successfully isolated stem cells from human skin, expanded them in the laboratory and coaxed them into becoming fat, muscle and bone cells.
Johns Hopkins scientists have developed a way to study the earliest steps of human blood development using human embryonic stem cells grown in a lab dish instead of the embryos themselves.
Regenerative medicine scientists at the University of Florida's McKnight Brain Institute have created a system in rodent models that for the first time duplicates neurogenesis -- the process of generating new brain cells -- in a dish.
Baby and wisdom teeth, along with jawbone and periodontal ligament, are non-controversial sources of stem cells that could be "banked" for future health needs, according to a National Institutes of Health researcher who spoke today at the American Dental Association's national media conference.
New research from University of North Carolina at Chapel Hill shows how a protein may be crucial to the regulation of genes in embryonic stem cells. Findings offer new ideas on disease states.
The premature use of stem cell therapy could put many patients at risk of viral or prion diseases unless appropriate safety systems are in place, warn experts.
Researchers in the lab of Whitehead Institute Member Rudolf Jaenisch have discovered a mechanism that might enable scientists to multiply adult stem cells quickly and efficiently.
A comprehensive study from Canada's Robarts Research Institute has pinpointed two genes that shed significant light on why stem cells divide and develop less vigorously as we age.
Researchers at Johns Hopkins have begun what is believed to be the first clinical trial in the United States of adult mesenchymal stem cells to repair muscle damaged by heart attack, or myocardial infarct.
The growth and maintenance of human embryonic stem cells in the absence of contaminated animal products has been demonstrated by University of California, San Diego (UCSD) School of Medicine researchers in the Whittier Institute*, La Jolla, California.
Researchers have used a new microscopic, three-dimensional scaffolding to coax mouse stem cells to transform themselves into fat cells, and then to function identically to how fat cells naturally do in the body.
A lightning-fast laser technique has provided laboratory demonstrations of accurate, real-time, high-throughput identification of liver tumor cells at their earliest stages, and without invasive chemical reagents.
In a paper, researchers from the National Institute on Drug Abuse, the National Institute of Aging, and BresaGen, Inc. found that a variant line of human embryonic stem cells may serve as a potential model for studies of dopaminergic neuronal differentiation of hESCs.
Researchers have developed a method for mass-producing embryonic stem cells.
The L.A. Times Book Prize has included The Proteus Effect: Stem Cells and Their Promise for Medicine by Ann B. Parson on its list of finalists for the 2004 prize in the Science & Technology category.
It has long been thought that cells that regenerate tissue do so by regressing to a developmentally younger state. Now two University of Washington researchers have demonstrated that cells can regenerate without becoming "younger."
Stem cell researchers have shown how cosmetic surgery, such as wrinkle removal and breast augmentation, might be improved with natural implants that keep their original size and shape better than synthetics.
Mouse embryonic stem cells treated in culture with a growth factor and then injected into the liver reverse a form of hemophilia in mice analogous to hemophilia B in humans, a study from the University of North Carolina at Chapel Hill shows.
The first evidence of cardiac progenitor cells "“ rare, specialized stem cells located in the newborn heart of rats, mice and humans "“ has been shown by researchers at the UCSD. The cells are capable of differentiation into fully mature heart tissue.
A Medical College of Wisconsin research team, led by John W. Lough, Ph.D., professor of cell biology, neurobiology and anatomy has found that embryonic stem cells in animals can be cultivated to form new tissue, which eventually may help doctors learn how to replace tissue damaged as a result of a heart attack.
Using the common fruit fly, researchers at UT Southwestern Medical Center have discovered that an intricate set of signals released by stem cells' surroundings governs their maintenance.
Currently available lines of human embryonic stem cells have been contaminated with a non-human molecule that compromises their potential therapeutic use in human subjects, according to research at UCSD and the Salk Institute in La Jolla.
Once a mere fantasy, the idea of growing new, healthy heart tissue to replace damaged or diseased heart muscle is inching closer to reality. Researchers are exploring several routes to grow new heart muscle, according to the January issue of the Harvard Heart Letter.
Stem cells from human umbilical cord blood effectively treated heart attacks in an animal study, report researchers at the University of South Florida and James A. Haley Veterans' Hospital.
Biologists at the University of California, San Diego have found a fundamental mechanism used by embryonic stem cells to assure that genetically damaged stem cells do not divide and pass along the damage to daughter stem cells.
In experiments in the lab and with guinea pigs, researchers have found the first evidence that genetically engineered heart cells derived from human embryonic stem cells might one day be a promising biological alternative to the electronic pacemakers used by hundreds of thousands of people worldwide.
Regeneration of damaged hearts using blood stem cells now appears to be clinically promising, say researchers who show that in mice, human stem cells use different methods to morph into two kinds of cells needed to restore heart function.
Johns Hopkins researcher John Gearhart has taken another small step on the road toward replenishing damaged cardiac tissue with pre-cursor cardiac cells grown from human embryonic stem cells (ES cells) in a highly reproducible system through controlled ES cell differentiation.
As it does every December, the Harvard Health Letter has chosen the top 10 health stories of the year. This year's winners include 1-new cholesterol guidelines, 2-cloning for stem cells, 3-Vioxx, and more.
A new study confirms that stem cells derived from the umbilical cords of newborn babies are a viable and effective transplant source for thousands of leukemia patients who have no other treatment option.
Johns Hopkins researchers say there is growing evidence that stem cells gone awry in their efforts to repair tissue damage could help explain why long-term irritation, such as from alcohol or heartburn, can create a breeding ground for certain cancers.
Biological science is now caught under a political microscope -- one that will continue no matter who sits in the White House in future years.
Cells from skeletal muscle could be an important source of stem cells for repairing damaged muscle or nerve tissue, suggest authors of a research article.
For the first time researchers have shown that transplanted stem cells can preserve and improve vision in eyes damaged by retinal disease.
Results from an animal study conducted at Johns Hopkins show that stem cell therapy can be used effectively to treat heart attacks, or myocardial infarcts, in pigs. Stem cells taken from another pig's bone marrow, when injected into the animal's damaged heart, were able to restore the heart's function to its original condition.
In human and animal studies, scientists at Johns Hopkins have developed a fast and safe method for collecting heart stem cells from remarkably small amounts of biopsied heart tissue (15 mg or less), and growing the cells in the lab to get more.
A top National Institutes of Health researcher predicted that the metallic prosthetic devices currently being used to replace joints in the body destroyed by osteoarthritis and other degenerative diseases will one day be replaced by healthy bone and cartilage tissue.
A "pdf" version of "Cell Biology 2004," the press book for the ASCB Annual Meeting, Dec. 4-8, is now accessible to registered science journalists. Registration is free, carries no obligation to attend, and is thus one heck of a deal.
The first test in humans of a bioartificial kidney offers hope of the device's potential to save the lives of people with acute renal failure, researchers at the University of Michigan Health System report.
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