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Exercising at a high level doesn’t affect the progression of calcium buildup in the arteries, even among older athletes such as marathoners who tend to have higher coronary artery calcium (CAC) scores, according to new research from UT Southwestern Medical Center. But a longer duration of exercise is associated with higher CAC.
The Association for Molecular Pathology (AMP) has published a set of evidence-based recommendations for the analytical validation and reporting of tumor mutational burden (TMB) testing as a potential predictive biomarker for immune checkpoint inhibitor (ICI) therapies. These recommendations encompass pre-analytical, analytical, and post-analytical factors of TMB analysis, and emphasize the importance of comprehensive methodological descriptions in publications to allow comparability between assays.
Dark matter is a hypothetical form of matter that is implied by gravitational effects that can’t be explained by general relativity unless more matter is present in the universe than can be seen. It remains virtually as mysterious as it was nearly a century ago when first suggested by Dutch astronomer Jan Oort in 1932 to explain the so-called “missing mass” necessary for things like galaxies to clump together.
Johns Hopkins Medicine scientists say they have developed an artificial lymph node with the potential to treat cancer, according to a new study in mice and human cells.
Scientists from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago have discovered a way to regenerate damaged heart muscle cells in mice, a development which may provide a new avenue for treating congenital heart defects in children and heart attack damage in adults, according to a study published in the Journal of Clinical Investigation.
Restricting menthol flavor in cigarettes while making nicotine replacement therapy, such as a skin patch that can help ease withdrawal, more available and affordable has the potential to reduce socioeconomic disparities in tobacco use.
An acoustic transmitter – or tag – emits unique signals or “pings” when scientists want to study the long-distance movement of marine animals. However, this method has limitations. Using a pioneering movement model, researchers reconstructed animal tracks and leveraged an iterative process to measure the accuracy and precision of these reconstructions from acoustic telemetry data. Results demonstrate how researchers can apply these techniques and measure the accuracy and precision of the methods to their study sites.
In a substantial milestone for supercomputing-aided drug design, Lawrence Livermore National Laboratory (LLNL) and BridgeBio Oncology Therapeutics (BridgeBio) today announced clinical trials have begun for a first-in-class medication that targets specific genetic mutations implicated in many types of cancer.
Hiring teams need to teach machine learning algorithms how hiring works to find the best candidates.
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