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Volume 29, Issue 2 of SLAS Discovery features two review articles, six original research articles covering phenotypic screening perspectives, medulloblastoma therapies and interventions for neurodegenerative diseases.
Volume 29, Issue 2 of SLAS Technology, includes three original research articles covering skin cutaneous melanoma, glycan-bead coupling and acoustic ejection mass spectrometry, and eight articles from the Advances in Synthetic Biology Special Issue.
The American Society for Radiation Oncology (ASTRO) published an updated clinical guideline that details best practices for treating patients who have symptomatic bone metastases and ways to improve their quality of life. The guideline is available as a free access article in Practical Radiation Oncology. “Radiation therapy is a cornerstone of care for patients with symptomatic bone metastases, offering a nonsurgical option for fast pain relief and improved quality of life with minimal side effects,” said Tracy Balboni, MD, MPH, chair of the guideline task force.
A recent review explores the innovative use of self-assembled protein nanoparticles (SAPNs) and virus-like particles (VLPs) in veterinary vaccine development. The research highlights the superior safety and efficacy of these nanovaccines over traditional formulations, offering a promising future for animal health and disease prevention.
An experimental mRNA vaccine against avian influenza virus H5N1 is highly effective in preventing severe illness and death in preclinical models. The vaccine could potentially help manage the outbreak of the H5N1 virus currently circulating in birds and cattle in the United States, and prevent human infections with the virus.
Scientists have made discoveries about light particles known as photons that could aid the quest for fusion energy.
Investigadores de Mayo Clinic están utilizando la tecnología para producir modelos de tejidos de diferentes partes del cuerpo con el fin de estudiar órganos y tejidos dañados o enfermos. Imaginan el día en que una bioimpresora 3D pueda moldear células vivas para tratamientos o curas de trastornos complejos.
Cold stress significantly hampers tomato growth and yield. Recent research reveals that 5-aminolevulinic acid (ALA) enhances cold tolerance in tomatoes by regulating the SlMYB4/SlMYB88-SlGSTU43 gene module. This discovery opens new avenues for genetic engineering to develop cold-resistant tomato varieties, potentially ensuring better crop resilience and productivity under low-temperature conditions.
In the rapidly evolving world of cryptocurrency, volatility management remains a crucial challenge. Researchers have now developed a novel approach that integrates Exponential Generalized Autoregressive Conditional Heteroskedasticity (EGARCH) with genetic algorithms and neural networks to enhance the precision of trading decisions in this volatile market.
A new assembly toolkit, an efficient assembly toolkit (PMAT), is set to revolutionize the study of plant mitochondrial genomes (mitogenomes), offering an unprecedented approach to understanding plant evolution and cytoplasmic male sterile line breeding. This tool stands to overcome significant challenges in the complete assembly of plant mitogenomes, a task previously hindered by complex recombination events and horizontal gene transfers.
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