“Metabolic Inhibitor” Compound Extends Survival in Mice with MYC-Expressing Pediatric Brain Tumors
Johns Hopkins MedicineVersions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene, according to results of two studies from researchers at the Johns Hopkins Kimmel Cancer Center.