The virus that causes COVID-19 normally gets inside cells by attaching to a protein called ACE2. Researchers at Washington University School of Medicine in St. Louis have found that a single mutation confers the ability to enter cells through another route, which may threaten the effectiveness of COVID-19 vaccines and therapeutics designed to block the standard route of entry.
Using a diverse set of tools, the lab of Randall Martin shows how the pandemic did – or didn’t – affect levels of particulate matter during COVID lockdowns.
An ongoing international Alzheimer's clinical trial has found that one drug, gantenerumab, improved biomarkers of disease despite unclear cognitive effects, prompting study leaders to offer participants the option of continuing to receive the drug and participate in follow-up examinations as part of a so-called open label extension.
Researchers at Washington University School of Medicine in St. Louis have found that high levels of a normal protein associated with reduced heart disease also protect against Alzheimer’s-like damage in mice, opening up new approaches to slowing or stopping brain damage and cognitive decline in people with Alzheimer’s.
A study from Washington University School of Medicine in St. Louis suggests that many, but not all, COVID-19 therapies made from combinations of two antibodies are effective against a wide range of virus variants, and that combination therapies appear to prevent the emergence of drug resistance.
A large, retrospective, multicenter study involving Washington University School of Medicine in St. Louis indicates that convalescent plasma from recovered COVID-19 patients can dramatically improve likelihood of survival among blood cancer patients hospitalized with the virus. The therapy involves transfusing plasma — the pale yellow liquid in blood that is rich in antibodies — from people who have recovered from COVID-19 into patients who have leukemia, lymphoma or other blood cancers and are hospitalized with the viral infection.
A study led by researchers at Washington University School of Medicine in St. Louis has identified a protein in the immune system that may protect babies from necrotizing enterocolitis, a leading cause of death among premature infants.
What exactly triggers a sneeze? A team led by researchers at Washington University School of Medicine in St. Louis has identified, in mice, specific cells and proteins that control the sneeze reflex. Better understanding of what causes us to sneeze — specifically how neurons behave in response to allergens and viruses — may point to treatments capable of slowing the spread of infectious respiratory diseases.
New research from Washington University in St. Louis sheds light on how — and in what context — peacekeepers can contain the spread of violence in fragile post-conflict areas.
Comprehensive evaluation of source sector, fuel contributions to the PM2.5 disease burden analyzed across over 200 countries
Summer picnics and barbecues are only a few weeks away! As excited as you are to indulge this summer, Escherichia coli bacteria are eager to feast on the all-you-can-eat buffet they are about to experience in your gut. However, something unexpected will occur as E. coli cells end their journey through your digestive tract. Without warning, they will find themselves swimming in your toilet bowl, clinging to the last bits of nutrients attached to their bodies.
Faculty from the McKelvey School of Engineering and the School of Medicine teamed up to design better grafts for dialysis patients.
Researchers at Washington University School of Medicine in St. Louis have identified the brain regions involved in choosing whether to find out if a bad event is about to happen.
A new study led by Washington University School of Medicine in St. Louis provides new guidance on the treatment of medulloblastoma, a pediatric brain cancer. Some aspects of radiation therapy may be reduced while still providing effective treatment.
Researchers at Washington University School of Medicine in St. Louis and the University of Chicago have found that a single, one-hour treatment that involves breathing in a mixture of oxygen and the anesthetic drug nitrous oxide — otherwise known as laughing gas — can significantly improve symptoms in people with treatment-resistant depression.
Research from Washington University School of Medicine in St. Louis shows that international travelers often return home with new bacterial strains jostling for position among the thousands that normally reside within the gut microbiome. Such travel is contributing to the rapid global increase and spread of antimicrobial resistance.
The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial led by Washington University School of Medicine in St. Louis. The drug is designed to shut down the effects of the mutation, which is found in about 13% of patients with lung adenocarcinoma, a common type of non-small-cell lung cancer.
Researchers at Washington University School of Medicine in St. Louis have discovered that the immune cells that protect the brain and spinal cord come primarily from the skull. The finding opens up the possibility of developing therapies to target such cells as a way to prevent or treat brain conditions.
Interdisciplinary team finds combining certain data after a patient's first treatment can predict how a tumor will respond to chemotherapy.
Researchers at Washington University School of Medicine in St. Louis and Cornell University have collaborated to implant insulin-secreting beta cells grown from human stem cells into mice with diabetes, to normalize their blood sugar.
New research published in PLOS Biology emphasizes the importance of prioritizing taxonomic research in conservation, with biodiversity loss greater than realized due to the high number of unknown and undocumented species. Jane Melville, senior curator of terrestrial vertebrates at Museums Victoria and associate professor in the School of Biological Sciences at Monash University, led the collaborative research effort as part of a Fulbright Fellowship at Washington University in St.
Global oceans absorb about 25% of the carbon dioxide released into the atmosphere when fossil fuels are burned. Electricity-eating bacteria known as photoferrotrophs could provide a boost to this essential process, according to new research from Washington University in St. Louis.Scientists led by Arpita Bose, assistant professor of biology in Arts & Sciences, found that bacteria found in brackish sediments can “eat” electricity and, in the process, absorb and lock away climate-warming carbon dioxide.
A team at Washington University in St. Louis has developed a new brain stimulation technique using focused ultrasound that is able to turn specific types of neurons in the brain on and off and precisely control motor activity without surgical device implantation.
New research from Washington University School of Medicine in St. Louis has found that postponing lung cancer surgery for more than 12 weeks from the date of diagnosis with a CT scan is associated with a higher risk of recurrence and death.
Research from Washington University in St. Louis reveals an underlying mechanism for how pauses allow neurons in the midbrain to recover from stimulation.
Researchers at Washington University School of Medicine in St. Louis and Stanford University School of Medicine have found that normal exposure to light can drive the formation and growth of optic nerve tumors in mice — and maybe people — with a genetic predisposition. Such tumors can lead to vision loss.
A new study from Washington University School of Medicine in St. Louis suggests that, among men, low testosterone levels in the blood are linked to more severe COVID-19. The study contradicts widespread assumptions that higher testosterone may explain why men, on average, develop more severe COVID-19 than women do.
Just in time for picnic-table trivia, a new study published rewrites the origins of domesticated watermelons.Using DNA from greenhouse-grown plants representing all species and hundreds of varieties of watermelon, scientists discovered that watermelons most likely came from wild crop progenitors in northeast Africa.
Researchers discovered how individual phytochrome isoforms respond differently to light intensity and temperature, enabling land plants to colonize the planet many millions of years ago -- and allowing plants to acclimate to a wide array of terrestrial environments.
People who have had a mild case of COVID-19 are left with long-term antibody protection against future disease, according to a study from researchers at Washington University School of Medicine in St. Louis.
The new CDC guidelines may help businesses – especially restaurants and bars – if customers feel safer with the new recommendations, according to Olin Business School's Raphael Thomadsen and Song Yao.
Today’s consumers are more attuned to brands’ values and willing to pay a premium to support companies that share their values, according to new research from the Bauer Leadership Center at Washington University in St. Louis and Vrity.
Eating a Western diet impairs the immune system in the gut in ways that could increase risk of infection and inflammatory bowel disease, according to a study from researchers at Washington University School of Medicine in St. Louis and Cleveland Clinic.
A team led by researchers including Jianmin Cui, professor of biomedical engineering, discovered a compound that prevents and even reverses the underlying physiological change that can lead some drugs to cause heart problems.
Researchers at Washington University School of Medicine in St. Louis have found that although the vast majority of people with alcohol use disorder see their doctors regularly for a range of issues, fewer than one in 10 ever get treatment to help curb their drinking.
A new study with zebrafish shows that a deadly form of skin cancer — melanoma — alters the metabolism of healthy tissues elsewhere in the body. The research from Washington University in St. Louis suggests that these other tissues could potentially be targeted to help treat cancer.“Tumors rely on a constant supply of nutrients to grow.
Matthew Kreuter, the Kahn Family Professor of Public Health at the Brown School, has received $1.9 million in grants to help increase COVID-19 vaccinations among Blacks in St. Louis City and County.
New research from Washington University School of Medicine in St. Louis shows that non-Hispanic African American women with triple-negative breast cancer do not fare as well as non-Hispanic white women with this type of breast cancer. The study demonstrates the need for additional research to address disparities in cancer care and understand whether tumor biology or nonbiological reasons such as systemic racism — or a combination of such factors — may be driving these disparities.
It took an unlikely food innovation — earth-friendly vegetarian patties, made to taste and “bleed” like the familiar meaty ones — to make people aware of heme. But heme is an essential part of proteins found in most life forms, from tiny bacteria to soy plants to the human body. Heme plays a crucial role in supplying cells with the energy needed to carry out chemical reactions.
A new system developed in the lab of Zhen (Jason) He uses bacteria to filter wastewater while creating electricity.
A new study led by Washington University School of Medicine in St. Louis has found a link between drinking sugar-sweetened beverages and an increased risk of developing colorectal cancer in women under age 50. The findings suggest that heavy consumption of sugary drinks during adolescence (ages 13 to 18) and adulthood can increase the disease risk.
The lab of Peng Bai has developed a stable, anode-free sodium ion battery that is highly efficient, will be less expensive and is significantly smaller than a traditional lithium ion battery.
The U.S. Food and Drug Administration’s proposed ban on menthol-flavored cigarettes and all flavored cigars could be particularly beneficial for Black and young people, says an expert on tobacco control at Washington University in St. Louis.“Around 80% of adult Black smokers and more than half of people age 18-34 use menthol brands,” said Todd Combs, research assistant professor at the Brown School who works on the Advancing Science & Practice in the Retail Environment (ASPiRE) project, which uses agent-based modeling to test the potential impact of retail tobacco policies.
Researchers at Washington University School of Medicine in St. Louis have found that improving the function of the brain's drainage network, known as the meningeal lymphatics, can make certain experimental Alzheimer’s therapies more effective in mice.
People rarely have just one motivation to do something. New research from the lab of Todd Braver at Washington University in St. Louis suggests how, and where, they combine.
In the first clinical trial of nicotinamide mononucleotide (NMN), researchers at Washington University School of Medicine in St. Louis have found that the compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice also has clinically relevant effects in people.
A new study from Washington University School of Medicine in St. Louis shows that even mild cases of COVID-19 increase the risk of death in the six months following diagnosis and that this risk increases with disease severity. The comprehensive study also catalogues the wide-ranging and long-term health problems often triggered by the infection, even among those not hospitalized.
Former Minneapolis police officer Derek Chauvin was convicted April 20 on three charges in the death of George Floyd. Collectively, people across the country breathed a sigh of relief because far too often, the story has been police killing people of color with impunity, says an expert on race and the law at Washington University in St.
When faced with a cutting-edge technological idea, business leaders who approach the idea in more concrete terms are more likely to recognize its utility, which increases their propensity to invest, according to new research from the Olin Business School at Washington University in St. Louis.
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