Previous studies have shown that antiviral treatment reduces the incidence of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). But now, researchers from the Division of Gastroenterology and Hepatology at Thomas Jefferson University are reporting that the antiviral therapy also prevents recurrence of HCC and extends patients’ lives.
Scientists from the Kimmel Cancer Center at Jefferson have found that interleukin-10 production in tumor cells is a possible prognostic factor in patients with advanced melanoma who are treated with autologous melanoma cell vaccine. They are presenting their data at the 2010 ASCO Annual Meeting in Chicago (Abstract #8588).
Patients with high-grade gliomas who experience acute (early) neurological toxicity during their treatment were more likely to experience chronic (late) neurological toxicity and shortened overall survival, according to researchers from the Kimmel Cancer Center at Jefferson. The study will be presented at the 2010 ASCO Annual Meeting in Chicago (Abstract #2037).
A gene shown to play a role in the aging process appears to play a role in the regulation of the differentiation of embryonic stem cells, according to researchers from the Center for Stem Cell Biology and Regenerative Medicine and the Department of Medicine at Thomas Jefferson University.
It is a commonly held that information on Wikipedia should not be trusted, since it is written and edited by non-experts without professional oversight. But researchers from the Kimmel Cancer Center at Jefferson have found differently, according to data being presented at the 2010 ASCO Annual Meeting in Chicago. (Abstract #6058).
Adam P. Dicker, M.D., Ph.D., has been appointed chairman of the department of Radiation Oncology at Jefferson Medical College of Thomas Jefferson University. Dr. Dicker is an international authority in radiation oncology, drug development, and the treatment of prostate cancer and brain tumors.
Researchers from the Kimmel Cancer Center at Jefferson have found that Stat5, a signaling protein previously found to be key to survival of prostate cancer, is also involved in metastasis.
Patients who received hypofractionated stereotactic radiotherapy for their recurrent brain cancers lived longer lives, according to researchers at Thomas Jefferson University.
Bladder cancer often becomes aggressive and spreads in patients despite treatment, but now researchers at the Kimmel Cancer Center at Jefferson have identified a protein they believe is involved in pushing tumors to become invasive – and deadly.
Researchers in the Department of Biochemistry and Molecular Biology at Thomas Jefferson University have found that the level of a single protein in the tiny roundworm C. elegans determines how long it lives.
A research team from the Department of Surgery at Jefferson Medical College of Thomas Jefferson University has concluded MBPs offer no clinical benefit to patients undergoing a pancreaticoduodenectomy. The results are set to appear in the August 2010 edition of the journal Surgery.
Researchers at Thomas Jefferson University have found that colonoscopy preparation drugs administered the same day as the procedure are equally effective to those given the night before and the morning of the procedure, but result in less complaints of side effects such as abdominal pain, sleep loss and workday interference.
Benjamin Solomon Carson, Sr., M.D., will address the graduating classes at the 186th annual commencement exercises for Jefferson Medical College and Jefferson College of Graduate Studies. He will receive an honorary doctor of science degree during the Monday, May 24th ceremonies at 10:30 a.m., at the Kimmel Center for the Performing Arts on South Broad Street in Philadelphia.
Cataldo Doria, M.D., Ph.D., Nicoletti Family Professor of Transplant Surgery at Jefferson Medical College of Thomas Jefferson University, and director of the Division of Transplantation at Thomas Jefferson University Hospital is the first transplant surgeon in the United States to use a new totally artificial liver assist device as a bridge to transplantation.
Sun Yong (Sunny) Lee, M.D., has recently been appointed assistant director at the Jefferson Breast Care Center , and has been appointed an assistant professor in the Department of Surgery at Jefferson Medical College of Thomas Jefferson University.
According to a study conducted at Thomas Jefferson University (TJU), non-invasive coronary computed tomography angiography (CTA) is a cost-effective alternative to invasive cardiac catheterization in the care of patients who have positive stress test results but a less than 50 percent chance of actually having significant coronary artery disease (CAD).
Molecular biologist Jonathan Brody, Ph.D., assistant professor, Department of Surgery at Jefferson Medical College of Thomas Jefferson University, has been awarded a 2010 Pancreatic Cancer Action Network – American Association of Cancer Research (AACR) Career Development Award in memory of Skip Viragh. This two-year grant awards $200,000 to Dr. Brody to help support his innovative research in pancreatic cancer. He will receive recognition for his work at the 2010 AACR annual meeting in Washington, D.C. on April 20th.
Rex G. Mathew, M.D., F.A.C.E.P., vice president of Emergency Medicine Clinical Operations at Thomas Jefferson University Hospital (TJUH) has been named the Emergency Department Director of the Year by the Emergency Medicine Foundation and Blue Jay Consulting. Dr. Mathew will receive his award at the American College of Emergency Physicians Emergency Department Director’s Academy on April 26th.
The Commission on Accreditation of Rehabilitation Facilities (CARF) International recently announced that the inpatient rehabilitation program and stroke specialty program of the Comprehensive Acute Rehabilitation Unit of the Department of Rehabilitation Medicine at Thomas Jefferson University Hospital have again been re-accredited for a period of three years. The accreditation extends through February 2013.
Leonard Gomella, M.D., F.A.C.S., the Bernard W. Godwin, Jr. Professor of Prostate Cancer, associate director for Clinical Affairs at the Kimmel Cancer Center (KCC) at Jefferson, and Chair of the Department of Urology at Jefferson Medical College of Thomas Jefferson University, has been appointed the new Editor-in-Chief of The Canadian Journal of Urology (CJU).
Adam Berger, M.D., a Cancer Liaison Physician (CLP) at Thomas Jefferson University Hospital, recently received an Outstanding Performance Award for going above and beyond the scope of the normal duties of serving as a liaison between the hospital’s cancer program and the American College of Surgeons Commission on Cancer (CoC). As a Cancer Liaison, he is serving a three-year appointment and is among a national network of over 1,600 volunteer physicians who are responsible for providing leadership and direction to establish, maintain and support their facility’s cancer program.
The new Jefferson Vascular Center (JVC) at Thomas Jefferson University Hospital offers an integrated, multidisciplinary approach to the diagnosis, management and treatment of vascular diseases (diseases of blood vessels) and thrombotic (blood-clotting) disorders all under one roof. Millions of adults in the United States develop thrombotic disorders every year so having a state-of-the-art center with all the clinical and diagnostic tools in one localized area provides the best possible treatment options for patients.
As hospitals across the United States strive to operate efficient and effective emergency departments (EDs) in the face of today’s increasingly strained health care environment, Thomas Jefferson University Hospital (TJUH) celebrates its early successes in Urgent Matters, a groundbreaking effort to reduce ED overcrowding, which involves just six hand-selected hospitals across the country, including TJUH.
The levels of an inflammatory chemokine were significantly elevated in patients with pancreatic cancer who were extremely obese, according to research conducted by scientists at the Jefferson Pancreatic, Biliary and Related Cancers Center. They presented their data at the 5th Annual Academic Surgical Congress, held in San Antonio.
Researchers from the Kimmel Cancer Center at Jefferson have found a mechanism by which a hormone responsible for milk production blocks an oncogene that makes breast cancer more aggressive.
Jack Jallo, M.D., Ph.D., F.A.C.S., recently joined the Department of Neurological Surgery at Jefferson Hospital for Neuroscience, and was named a professor at Jefferson Medical College of Thomas Jefferson University.
Researchers from the Biotechnology Foundation Laboratories at Thomas Jefferson University have identified a way to increase the oil in tobacco plant leaves, which may be the next step in using the plants for biofuel. Their paper was published online in Plant Biotechnology Journal.
Scientists from the Kimmel Cancer Center at Jefferson have discovered a possible way for malignant breast tumors to be identified, without the need for a biopsy. The findings were published online ahead of print in the Journal of Nuclear Medicine.
Researchers from Thomas Jefferson University are one step closer to developing a vaccine against the AIDS disease.
New treatment guidelines for patients with brain metastases are now available from the American Association of Neurological Surgeons (AANS) and the Congress of Neurological Surgeons (CNS).
Irwin B. Levitan, Ph.D., has been named Founding Chair of the newly created Department of Neuroscience at Jefferson Medical College of Thomas Jefferson University. He has also been appointed director of the Farber Institute for Neurosciences. His appointment is effective January 1, 2010.
Publishing in PLoS Pathogens, researchers at from the Kimmel Cancer Center at Jefferson have found a novel mechanism by which drugs block HIV-1 from entering host cells.
Researchers from the Center for Translational Medicine at Thomas Jefferson University have found that the overexpression of a sodium/calcium exchanger, without changes in other ion transport pathways commonly observed in heart failure, does not by itself lead to contraction abnormalities in the heart. They presented the data from the study at the American Heart Association Scientific Sessions in Orlando, Fla.
Inhibition of a protein known to contribute to heart failure also appears to be protective of the heart in more acute cardiac stress injury, namely ischemia reperfusion, according to two studies conducted at the Center for Translational Medicine at Thomas Jefferson University. The studies will be presented at the American Heart Association Scientific Sessions 2009 in Orlando, Fla.
Mark Weiss, M.D., will join the Thomas Jefferson University, Department of Medical Oncology as Director of Hematologic Malignancies. Dr. Weiss will be professor of Medical Oncology at Jefferson Medical College of Thomas Jefferson University. He comes to Jefferson after a 19-year career at Memorial Sloan-Kettering Cancer Center in New York City.
A protein long thought to be a secondary regulator in the heart’s response to stressors like hypertension actually appears to be a primary regulator according to researchers from the Center for Translational Medicine at Thomas Jefferson University. The data will be presented in the Late Breaking Science session at the American Heart Associations Scientific Sessions in Orlando, Fla.
A rapid decline in metabolic activity on a PET scan after radiation therapy for non-small cell lung cancer is correlated with good local tumor control, according to a study presented by researchers at Thomas Jefferson University Hospital at the 51st ASTRO Annual Meeting.
Four researchers from Thomas Jefferson University have received $3.9 million in Challenge grant funds as part of the American Recovery and Reinvestment Act.
Optic nerve sheath meningiomas are rare tumors that are traditionally treated with surgery, which is typically a blinding procedure. However, researchers from Thomas Jefferson University Hospital have found that a specialized type of radiation therapy offers the same local control, with fewer adverse effects on vision. The investigators presented their data at the 51st ASTRO Annual Meeting (Abstract #2676B-261).
Positron emission tomography (PET) imaging of non-small cell lung cancer prior to receiving radiation therapy should not be the basis for determining areas that may benefit from higher doses of radiation, according to research presented by investigators at Thomas Jefferson University Hospital at the 51st ASTRO Annual Meeting (Abstract #2583/B-186).
Radiation dose delivered to the prostate and nearby organs in every brachytherapy procedure should be carefully analyzed using post-implant CT or MRI and uniformly documented in every patient, according to a new guideline co-authored by Yan Yu, Ph.D., director of Medical Physics in the department of Radiation Oncology at Thomas Jefferson University.
The Department of Neurology at Jefferson Medical College (JMC) of Thomas Jefferson University has been awarded a multi-million dollar grant from the National Institutes of Health (NIH) for the creation of a center of excellence to study autoimmune diseases from basic science research to its translation into clinical applications. The five-year grant initially totals over $4 million, but could be as much as $10 million by the end of award period. The center is one of nine in the country and the only one in the Pennsylvania.
Thomas Jefferson University Hospital (TJUH) in Philadelphia is the first hospital in Pennsylvania to offer a FDA-approved device that helps individuals with certain types of spinal cord injuries breathe on their own again.
The Chest Pain Center in the Department of Emergency Medicine at Thomas Jefferson University Hospital (TJUH) recently received full Cycle II accreditation with PCI (percutaneous coronary intervention) from the Accreditation Review Committee of the Society of Chest Pain Centers (SCPC). With the rise of chest pain centers came the need to establish standards designed to improve the consistency and quality of care provided to patients. SCPC’s accreditation process insures centers meet or exceed quality-of-care measures in acute cardiac medicine.
Migraine sufferers, beware. You may be more prone to an alcohol-induced headache after a night of drinking, according to researchers from the Jefferson Headache Center. The research will be presented at Neuroscience 2009, the Annual Meeting of the Society for Neuroscience, in Chicago.
Infectious diseases currently cause about one-third of all human deaths worldwide, more than all forms of cancer combined. Advances in cell biology and microbial genetics have greatly enhanced understanding of the cause and mechanisms of infectious diseases. Researchers from Thomas Jefferson University, the Pasteur Institute in Paris, and Yale University reported in PLoS ONE, a way in which intracellular pathogens exploit the biological attributes of their hosts in order to escape destruction.
(PHILADELPHIA) Thomas Jefferson University is expanding and empowering its stem cell research program with a new academic department at Jefferson Medical College: Stem Cell Biology and Regenerative Medicine.
Gordon Schwartz, M.D., M.B.A., has been appointed director of the Jefferson Breast Care Center at the Kimmel Cancer Center (KCC), and will also return to the full-time faculty as a professor in Jefferson’s Department of Surgery. With more than 40 years of clinical and educational experience, Dr. Schwartz is an internationally renowned expert in breast diseases.
A team of researchers from Thomas Jefferson University and the University of Delaware have received a grant from the Department of Defense to create a three-dimensional patient imaging system that will allow surgeons to view and touch selected organs and tissues prior to surgery.
A recent United States Army study found that excessive bone growth, also known as heterotopic ossificiation (HO), affects up to 70 percent of soldiers who are severely wounded during combat. The excessive bone forms within muscles and other tissues causing severe pain, reduced mobility and even local paralysis if untreated. A new study by Thomas Jefferson University researchers found a way to prevent HO in animal models by shutting the process off in its early stages.
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