Clues to early onset colorectal cancer found in microbiome of Hispanic patients
UT Southwestern Medical Center
Results from phase two clinical trials at UT Southwestern Medical Center showed that a suspension of gold nanocrystals taken daily by patients with multiple sclerosis (MS) and Parkinson's disease (PD) significantly reversed deficits of metabolites linked to energy activity in the brain and resulted in functional improvements.
UT Southwestern Medical Center is partnering with Pfizer Inc. to develop RNA-enhanced delivery technologies for genetic medicine therapies through the Dallas-based medical center's Program in Genetic Drug Engineering.
Automated external defibrillators (AEDs) are underutilized during cardiac arrest episodes despite laws in some states requiring their availability in high-risk areas such as athletic facilities, researchers at UT Southwestern Medical Center found.
UT Southwestern Medical Center researchers have identified an experimental molecular compound that improved survival among cellular models and mouse models of amyotrophic lateral sclerosis (ALS), the fatal neurodegenerative disease.
Russell DeBose-Boyd, Ph.D., Professor of Molecular Genetics at UT Southwestern Medical Center, has been awarded the Hill Prize in Biological Sciences from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) in recognition of his long-standing research into a key mechanism necessary for cholesterol control.
Football fans who plan to attend food-and-beverage-packed Super Bowl parties should have a dietary game plan to ensure that watching the big game is a healthy affair, according to a lifestyle medicine expert at UT Southwestern Medical Center.
Nutritious meal kits and no-prep meals improved food security and perceived dietary quality among clients of a Dallas food pantry, according to a pilot study led by UT Southwestern Medical Center.
Researchers at UT Southwestern have developed a first-of-its-kind robotic nipple-sparing mastectomy (rNSM) and reconstruction procedure that provides remarkably natural-looking outcomes while preserving full breast sensation.
Electric scooters carry a significant risk of orthopedic injuries and associated costs for medical care, which can create a financial burden for the public, according to a study by UT Southwestern Medical Center researchers. The findings, published in the Journal of Orthopaedic Business, could have policy implications for the vehicles, which are available through vehicle-sharing programs in many cities worldwide.
By taking advantage of mechanisms that allow cancer cells to evade immune attack, UT Southwestern Medical Center researchers have developed a new strategy in animal models that has potential for treating ulcerative colitis.
Two studies led by a researcher at UT Southwestern Medical Center show the effects of different SARS-CoV-2 variants on lung tissue, revealing what may cause some COVID-19 infections to be more severe than others.
A study of mutant models of fragile X syndrome (FXS), a genetic disorder related to autism and intellectual disability, shows that activation of the cerebellum mitigates aberrant responses in sensory processing areas of the brain and improves neurodevelopmental behaviors. The findings, published by UT Southwestern Medical Center researchers in Cell Reports, could offer an opportunity for developing new therapies for neurocognitive disorders.
Vincent Tagliabracci, Ph.D., Associate Professor of Molecular Biology at UT Southwestern Medical Center, will receive the 2024 Edith and Peter O’Donnell Award in Biological Sciences from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) for broadening the understanding of pseudokinases, a family of enzymes that play key roles in many physiological and pathological processes.
UT Southwestern Medical Center joined leaders in Dallas and across the nation in mourning the loss and honoring the legacy of U.S. Rep. Eddie Bernice Johnson, an inspirational leader who helped advance the Medical Center’s science, research, clinical care, and educational initiatives during her extraordinary career representing the area.
An increased concentration of the hormone leptin in fat cells is believed to be responsible for weight gain associated with antipsychotic drugs, according to research led by UT Southwestern Medical Center. The study, published in Science Translational Medicine, used a mouse model to uncover the underlying mechanisms of unwanted metabolic side effects and to test an antibody that might reduce them.
Robotic surgery offers significant benefits over laparoscopic procedures for many patients undergoing colectomies for colon cancer, according to a study by UT Southwestern Medical Center.
A two-step screening protocol that combines clinical risk assessment with biomarker testing can more effectively identify which patients with Type 2 diabetes need medication to prevent heart failure, according to a study led by UT Southwestern Medical Center researchers.
The holiday season is a time for celebration, but too much celebrating can be bad for your health.
Office parties and family dinners make eating healthy during the holiday season a challenge. But you can still enjoy your favorite treats while maintaining a balanced diet, according to nutrition experts at UT Southwestern Medical Center.
While the holiday season can bring joy to people of all ages, it also leaves many feeling depressed and lonely.
The U.S. Food & Drug Administration has expanded the approved use of belzutifan for treatment of metastatic kidney cancer, another milestone for the novel, first-in-class kidney cancer drug arising from scientific discoveries at UT Southwestern Medical Center.
Despite the convenience of at-home screening tests for early detection of colorectal cancer (CRC), a study led by UT Southwestern Medical Center researchers examining more than a decade of patient data found that about 10% of the tests could not be processed, mostly due to patient error.
Jinming Gao, Ph.D., Professor of Biomedical Engineering, Cell Biology, Otolaryngology – Head and Neck Surgery, and Pharmacology at UT Southwestern Medical Center, has been selected as a fellow of the National Academy of Inventors (NAI) in recognition of his efforts to develop innovative nanotechnology platforms to improve cancer diagnosis and treatment.
Researchers at UT Southwestern Medical Center have developed a novel artificial intelligence (AI) model that analyzes the spatial arrangement of cells in tissue samples. This innovative approach, detailed in Nature Communications, accurately predicted outcomes for cancer patients, marking a significant advancement in utilizing AI for cancer prognosis and personalized treatment strategies.
UT Southwestern Medical Center is leading three multicenter clinical trials funded by the National Institute on Drug Abuse (NIDA) focused on potential treatments for methamphetamine or cocaine addiction.
Being pregnant during the holidays brings its own set of challenges whether you’re traveling to visit family and friends or just looking to get away.
A new study led by UT Southwestern Medical Center molecular biologists presents a novel culture system to grow both embryonic and extraembryonic stem cells, potentially providing important insights into the genesis of congenital malformations and early developmental disorders.
Tailoring prescriptions individually to a patient’s needs after cesarean delivery can decrease opioid use while successfully managing post-surgical pain, according to a new study by researchers at UT Southwestern Medical Center.
UT Southwestern Medical Center’s Harold C. Simmons Comprehensive Cancer Center is among the first in the nation and the first in Texas to offer radiation treatments using a new technology that combines positron emission tomography (PET) imaging with radiotherapy to precisely treat bone and lung cancers.
A dietary supplement developed by a UT Southwestern Medical Center researcher significantly reduced high blood sugar caused by a diuretic used to lower blood pressure while also correcting electrolyte imbalances, UTSW researchers report. The findings, published in Hypertension, could offer a solution for the serious side effects associated with this class of drugs.
Colorectal cancer (CRC) screening rates are similar among older adults despite varying 10-year mortality risks, UT Southwestern Medical Center researchers report in a new study.
We all know the popular holiday song “It’s the Most Wonderful Time of the Year.” But for many people, a more appropriate lyric might be “It’s the Most Stressful Time of the Year.”
A gene previously linked to autism spectrum disorder (ASD) by UT Southwestern Medical Center researchers appears to play an important role in steering cells in the brain’s hippocampus toward their ultimate identities, the same team reported in a new study.
More than a dozen UT Southwestern Medical Center scientists are included on the 2023 Highly Cited Researchers list, which recognizes the top 1% of researchers from around the world who have demonstrated significant and broad influence in their chosen field or fields of research.
Children who had preexisting health problems or who lived in the Southern United States had a higher risk for severe health outcomes from acute COVID-19 infections, according to researchers at UT Southwestern Medical Center. The results, reported in the journal Hospital Pediatrics that is published by the American Academy of Pediatrics, also showed the importance of vaccinations in reducing the severity of illness for those who became infected.
UT Southwestern Medical Center’s Simulation Center, which marks its fifth anniversary this year, is one of the most advanced facilities of its kind in the nation, offering an unparalleled environment for immersive learning at all levels – from first-year medical students to practicing health care professionals.
Newborn boys are significantly more likely than girls to have a brain injury called hypoxic-ischemic encephalopathy (HIE), researchers at UT Southwestern Medical Center report. The findings, published in JAMA Network Open, could lead to more effective HIE interventions for both boys and girls.
A targeted therapy using three different drugs significantly delayed progression and extended survival for breast cancer patients whose HER2 gene is mutated, a multicenter study co-led by researchers at UT Southwestern Medical Center shows. The findings, published in Annals of Oncology, suggest a new strategy for a difficult-to-treat form of breast cancer that has become resistant to other treatments and currently has no curative options.
Simple changes in patient ventilation procedures during out-of-hospital cardiopulmonary resuscitation (CPR) could lead to a dramatic improvement in cardiac arrest survival rates, according to a landmark study led by UT Southwestern Medical Center.
UT Southwestern Medical Center will lead a multi-institution effort to gather and assimilate information on the billions of sequences employed by immune receptors of the adaptive immune system. The project, funded by the National Institutes of Health, aims to improve the understanding of immunity and help facilitate the development of improved vaccines and treatments for many diseases.
Interactions among microorganisms within the human gut may be associated with increased anxiety levels in people with depression, according to research led by UT Southwestern Medical Center.
Low doses of an immunotherapy taken under the tongue safely achieved desensitization to peanut allergies in children ages 1 to 4 years, according to results of a clinical trial conducted by researchers at UT Southwestern Medical Center, Children’s Medical Center Dallas, and the University of North Carolina School of Medicine.
Measuring blood pressure while patients are standing rather than sitting may improve the accuracy of readings, UT Southwestern Medical Center researchers report. Their findings, published in Scientific Reports, could lead to significant improvements in early detection of high blood pressure in healthy adults.
Researchers led by a team at UT Southwestern Medical Center have developed a device that can isolate blood flow to the brain, keeping the organ alive and functioning independent from the rest of the body for several hours.
A preoperative nerve block used in combination with other medications can reduce the need for opioids to manage pain following spinal surgery, UT Southwestern Medical Center researchers found. The findings, published in European Spine Journal, suggest a way to lessen the reliance on opioids to reduce postoperative pain and help patients become ambulatory sooner.
A traditional Chinese medicine whose name means “to open the network of the heart” reduced the risk of heart attacks, deaths, and other major cardiovascular complications for at least a year after a first heart attack, a study led by UT Southwestern Medical Center researchers shows. The findings, published in JAMA, reveal the promise of this compound, one of the first traditional Chinese medicines tested in a large-scale, Western-style clinical trial.
State, regional, and business leaders joined researchers and students from UT Southwestern Medical Center and The University of Texas at Dallas for the dedication of the Texas Instruments Biomedical Engineering and Sciences Building that will accelerate training for the next generation and foster medical innovations to improve patient care.
Patients with endometriosis are more likely to experience complications during and after hysterectomies, a study by UT Southwestern Medical Center researchers shows.