Elucidation of Novel mechanisms regulating the tumor suppressor RBL1/p107 levels in mesothelioma and lung cancer cells
Sbarro Health Research Organization (SHRO)
The journal Critical Review In Eukaryotic Gene Expression has just published an interesting article entitled: “Fungal And Bacterial Biodeterioration Of Outdoor Canvas Paintings: The Case Of The Cloisters Of Quito, Ecuador.”
Sbarro Health Research Organization (SHRO) Founder and Director, Antonio Giordano, M.D., Ph.D., of Temple University and the University of Siena, Italy, is part of the GYNOCARE COST Action (CA18117) chaired by Prof Jean Calleja Agius of the University of Malta.
Building on prior success combining Cyclin-Dependent Kinase (CDK) inhibitors with hormone therapy to treat breast cancer, researchers are now exploring the potential integration of CDK inhibitors with radiotherapy in a paper issued in the International Journal of Molecular Sciences.
The isolation and abrupt interruption of social contacts and interpersonal affective relationships caused by the Covid-19 pandemic have triggered greater fragility and uncertainty in people and this condition has also had repercussions in the human-dog relationship.
Long non‑coding RNAs (lncRNAs) play a critical role in tumorigenesis.
The Polo Tecnologico Piemontese (PTP) is born in Candiolo (Turin), a hub of innovative companies that will host avant-garde technological companies and research institutes dedicated to medicine and which sees the HBW Group * as the leader.
Long Non-Codign RNAs (lncRNAs) are detectable in body fluids, such as the blood, saliva, and urine, and are therefore emerging as a novel method for cancer diagnosis, but few studies have explored the link between lncRNAs and choriocarcinoma (CC), a rare but serious type of cancer affecting the female reproductive organs.
Scientists use engineered protein coating that binds to receptors on the surface of corneal cells to improve drug uptake.
In patients with non-small cell Lung Cancer (NSCLC), the presence of either high chronic inflammation, or procalcitonin levels in the blood as a response to bacterial infection, both predict a poor response to treatment with immune checkpoint blockade.
At the prestigious setting of Villa Firenze, the Italian Embassy in Washington, DC, on the occasion of a farewell party for outgoing Ambassador Armando Varricchio, Professor Antonio Giordano was in attendance among the many high-ranking government officials and honored guests.
Inconsistencies, potential problems, and lack of access give researchers cause for concern's about the secretive development process.
A new study examines the recent literature on carbon nanotubes toxicity highlighting their strong inflammatory potential for the respiratory system.
A recently published paper addresses the threat posed by overstating the significance of inconclusive studies to the public by both the media and the scientific community itself.
The panel of experts will discuss recent trials that have demonstrated efficacy for the vaccine, despite an early release in August 2020 which was met with skepticism by the international community.
Sbarro Health Research Organization (SHRO) Founder and Director, Antonio Giordano, M.D., Ph.D., has recently published a landmark paper in collaboration with another 28 co-authors hailing from 14 different countries, as part of the GYNOCARE COST Action (CA18117).
On the 18th and 19th of February, Sbarro Health Research Organization (SHRO) Founder and Director, Antonio Giordano, M.D., Ph.D., will host an online medical conference titled, “Why do we need independent research in oncology?”
The National Italian American Foundation (NIAF) is now accepting applications for the inaugural class of Fauci Fellowships, created in recognition of Dr. Anthony S. Fauci’s contributions to humanity and the medical and scientific community.
Breast and ovarian cancer are two of the deadliest malignancies among women worldwide.
The emergence of Severe Acute Respiratory Syndrome (SARS) in 2003 and Middle East Respiratory Syndrome (MERS) in 2012, caused by SARS-CoVand MERS-CoV, respectively, demonstrated the zoonotic potential of coronaviruses.
Written while the filmmaker was undergoing chemotherapy in 2018, Randa Ghattas' short film, “Hug Me Dad,” is dedicated in part to Giordano, who advised her on the course of her treatment.
National Italian American Foundation (NIAF) board member and Sbarro Health Research Organization (SHRO) founder Dr. Antonio Giordano congratulates Dr. Anthony Fauci on his awarding of the Leonardo da Vinci Award for Leadership in Health and Science at this year’s NIAF Anniversary Gala, held virtually on October 31st, 2020.
A study exploring a new combination of therapeutic agents has recently been published in the International Journal of Molecular Sciences, describing dl922-947, an oncolytic adenovirus, and AZD1775, an inhibitor of the DNA damage checkpoint kinase WEE1, and their possible efficacy to treat MPM.
Mesothelioma is a deadly cancer mainly caused by exposure to asbestos fibers.
These aspects may have important implications for the design of new drugs and therapeutic interventions for these progressive and incurable diseases.
Held in Locri, Italy on Saturday, August 8 in the enchanting Riviera dei Gelsomini, the Women of Talent Award ceremony recognized the achievements of Francesca Pentimalli, PhD, a frequent collaborator on research with the Sbarro Health Research Organization (SHRO).
Not long after the Coronavirus disease (Covid-19) outbreak in China, Italy was hard-hit by the infection and rapidly became one of the countries with the highest mortality rate.
Malignant mesothelioma (MM) is a lethal cancer mainly caused by exposure to asbestos, for which, unfortunately, no current treatment has proven effective, despite the identification of several promising therapeutic targets over the years.
A new class of anticancer agents can restore the ability of cytotoxic T lymphocytes (CTLs) to infiltrate the tumor and kill target cells in patients with metastatic non-small cell lung cancer (mNSCLC).
An international team of investigators has recently discovered that the receptor tyrosine-kinase EphA2 activated by the growth factor progranulin is a tumorigenic driver of bladder cancer progression.
Researchers predict the Human Leukocyte Antigen (HLA) gene has a key role in shaping immune response to COVID.
Silencing of the protein coding gene PRMT5 has possible therapeutic potential for treating Mesothelioma (MM), according to a recent in vitro study published in the Journal of Cellular and Molecular Medicine.
In Italy, a COVID-19 epidemic is raging. This analysis, which might be useful also to forecast the next epidemic trends in the U.S., is briefly recapitulated in the following document.
“The new virus originating from Wuhan is the third coronavirus that has made the ‘jump’ from animals to humans,” explains Enrico Bucci, Ph.D., professor and research scientist at the Sbarro Health Research Organization (SHRO), at Temple University in Philadelphia.
COVID-19 is similar in symptoms to the seasonal flu, but to recognize it there is a different procedure and we have to act accordingly
A team of investigators has recently discovered that the collagen receptor DDR1 functionally interacts with the insulin-like growth factor system in regulating bladder cancer.
An international team of researchers found that high BMI correlates to lower survival in patients with HER2+ metastatic breast cancer, even among patients showing initial positive response to new anti-HER2 agents pertuzumab and trastuzumab.
Virtual Reality during chemotherapy shown to improve breast cancer patients’ quality of life during the most stressful treatments, according to a recent study.
Today a team of researchers from the Department of Veterinary Medicine and Animal Production of the Federico II University of Naples, in collaboration with the Sbarro Health Research Organization (SHRO), at Temple University in Philadelphia, and the Department of Biotechnology at the University of Siena, Itay, has discovered the effectiveness of a new extract, of natural origin, able to prevent nephrotoxicity induced by the mycotoxin Ochratoxin A (OTA), and has published this research in the international Journal of Cellular Physiology.
The review has collected studies concerning the anticancer potential of curcumin against the most widespread cancers and also describing the molecular mechanisms of action.
A collaborative study of researchers from Thomas Jefferson University, Sbarro Institute for Cancer Research and Molecular Medicine of Temple University, University of Siena, and from the Spanish Center for the Applied Medical Research (CIMA) of the University of Navarra have discovered a novel targetable axis in mesothelioma patients.
Toxic environmental agents, to which anyone is involuntarily exposed, represent non-negligible risk for human health and, therefore, environmental contamination has become a theme of primary importance worldwide.
Panel to Convene at Annual Medical conference at NIAF
Sbarro Health Research Organization founder and Director, Antonio Giordano, M.D., Ph.D., has been recognized with a career award "for the great contributions he has made and which he will continue to make to science, medicine and research.
Results suggest that the combined treatment can lower the effective chemotherapy dosage, reduce side effects, improve tumor cell apoptosis, and reduce tumor cell migration.
Xylella fastidiosa, subsp. pauca is a bacterial pathogen currently devastating the olive orchards in Southern Italy (Apulia). Due to the epidemic, local production of olive oil has dropped by 90%, olive mills are shut down, the regional economy is suffering, and an invaluable cultural asset is compromised.