Researchers have identified for the first time an imbalance in a key neural pathway that explains how some people reactivate negative emotional memories. The finding could help scientists unlock new ways to treat psychiatric disorders such as post-traumatic stress disorder.
Irvine, Calif., April 8, 2019 — Both genetic codes and postal codes influence children’s physical and mental health and behavioral and social outcomes, according to a new study led by Candice Odgers, University of California, Irvine professor of psychological science, and Dan Belsky, assistant professor of epidemiology at Columbia University’s Mailman School of Public Health.
High-resolution images capture previously unseen features of PDE6. Included among them were some very promising regions that resemble fish-hooks. These regions are responsible for controlling PDE activity. By targeting the fish-hook-like region with a new class of PDE inhibitors, drug development companies may be able to eliminate unwanted side effects of certain PDE targeting drugs.
Irvine, Calif., April 3, 2019 – By focusing light down to the size of an atom, scientists at the University of California, Irvine have produced the first images of a molecule’s normal modes of vibration – the internal motions that drive the chemistry of all things, including the function of living cells. In a study in Nature, researchers at UCI’s Center for Chemistry at the Space-Time Limit describe how they positioned the atomically terminated silver tip of a scanning tunneling microscope mere ängstroms from its target: a cobalt-based porphyrin molecule affixed to a copper platform.
Irvine, Calif., March 20, 2019 – Here’s something to chew on: One in four people are impacted by defects of the temporomandibular – or jaw – joint. Despite the pervasiveness of this affliction, treatments are lacking, and many sufferers resort to palliative measures to cope with the pain and debilitation it causes. “The TMJ is central to chewing, talking and so many other daily activities, so when this crucial joint is impaired, there are significant negative effects on quality of life,” said Kyriacos A.
Irvine, Calif., March 19, 2019 — Bernadette Boden-Albala, Dr.P.H. – a renowned researcher and administrator whose efforts to reduce health disparities for America’s disadvantaged became a blueprint for community-based stroke and heart disease prevention – has been named director and founding dean of the University of California, Irvine’s planned School of Population Health, effective July 1.
Irvine, Calif., March 19, 2019 — Blending the power of big data and history, an expanded and redesigned version of Slave Voyages – one of the most utilized resources in the digital humanities – is now available. Housing both trans-Atlantic and intra-American slave trade databases, the Slave Voyages website illuminates the ubiquity of the slave trade from the 16th century to the 19th century.
UCI cognitive scientist studies how hormone cycles impact sleep and memory
Irvine, Calif., Feb. 28, 2019 — Child poverty in America could be decreased by 50 percent in a decade through a combination of work-oriented and income support programs, according to a national panel chaired by Greg Duncan, Distinguished Professor of education at the University of California, Irvine. The Committee on Building an Agenda to Reduce the Number of Children Living in Poverty by Half in 10 Years today announced its recommendations, based on a two-year evaluation of 20 program and policy ideas.
University of California, Irvine School of Medicine researcher Geoff Abbott, PhD, has been awarded a $2 million Outstanding Investigator Award/Maximizing Investigators’ Research Award (MIRA) R35 grant from the National Institute of General Medical Sciences, and a $1.7 million R01 grant from the National Institute of Neurological Disorders and Stroke.
About one in five adults in a representative sample of Americans had watched at least part of a beheading video created and posted online by the Islamic State group (formerly known as ISIS), according to a new study by the University of California, Irvine. Researchers also found that fear of terrorism and having a history of violent victimization appear to draw individuals to this highly graphic coverage – and that watching such videos was associated with global distress and fear of the future about two years after they went viral.
Irvine, Calif., Feb. 22, 2019 – During the DNA synthesis process in a laboratory, recordings can be made of the subtle, telltale noises made by synthesis machines. And those captured sounds can be used to reverse-engineer valuable, custom-designed genetic materials used in pharmaceuticals, agriculture and other bioengineering fields.
Project CLEAR clinical trial finds that the application of antiseptic soap, mouthwash, and nose ointments prevent post-discharge MRSA infections and hospitalizations. Patients
Irvine, Calif., Feb. 13, 2019 – Researchers at the University of California, Irvine have developed a wearable, disposable respiration monitor that provides high-fidelity readings on a continuous basis. It’s designed to help children with asthma and cystic fibrosis and others with chronic pulmonary conditions. The inexpensively produced sensors were created by UCI biomedical engineers using the popular children’s toy Shrinky Dinks, thin sheets of plastic that are painted or drawn on and then shrunk with heat.
Irvine, Calif., Feb. 12, 2019 — The University of California, Irvine has received a five-year, $5 million Institute of Education Sciences grant from the U.S. Department of Education to establish the first national research and development center focused on improving the writing skills of middle and high school students. The Writing Research to Improve Teaching and Evaluation Center for Secondary Students will conduct a study on academic writing in English language arts, science and history – in collaboration with researchers and subjects from the nearby Tustin Unified School District – and then create a professional development intervention program for teachers.
New insights on circumventing a key obstacle on the road to anti-scarring treatment have been published by Maksim Plikus, an associate professor in development and cell biology at the UCI School of Biological Sciences and colleagues in Nature Communications. The research team discovered that the natural scar-free skin repair process relies partially on assistance from circulating blood cells. The results point the way toward possible treatments for scar-free wound healing that target the body’s own blood cells.
Following a California Institute for Regenerative Medicine (CIRM) Independent Citizens Oversight Committee meeting held last week, University of California, Irvine (UCI) researchers learned they will receive $6 million in funding to support the continued development of a promising new treatment for Huntington’s disease (HD).
A University of California, Irvine-led study reveals that connectivity within the brain appears to be largely dictated by spatial architecture rather than cell type-specific cues. The study was published this month in Cell Reports.
Irvine, Calif., Jan. 23, 2019 — Online publishing platforms and digital media can provide opportunities for nonmainstream groups to push back against and offer alternatives to the simplistic stereotypes presented in literature and popular culture. A study led by the University of California, Irvine focused on Harry Potter fan fiction and discovered that autistic people, family members, teachers and advocates cast autistic characters in their stories in diverse ways that challenge typical representations.
Irvine, Calif., Jan. 15, 2019 — With a little help from HBO’s “Curb Your Enthusiasm,” University of California, Irvine neurobiologists have uncovered a key component of how the human brain marks time. Using high-powered functional MRI on college students watching the popular TV show, they were able to capture the processes by which the brain stores information related to when events happen, or what is known as temporal memory.
Irvine, Calif., Monday, Jan. 14, 2019 – Antarctica experienced a sixfold increase in yearly ice mass loss between 1979 and 2017, according to a study published today in Proceedings of the National Academy of Sciences. Glaciologists from the University of California, Irvine, NASA’s Jet Propulsion Laboratory and the Netherlands’ Utrecht University additionally found that the accelerated melting caused global sea levels to rise more than half an inch during that time.
In a University of California, Irvine-led study, researchers found evidence that fasting affects circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against aging-associated diseases. The study was published recently in Cell Reports.
Irvine, Calif., Dec. 18, 2018 — Dr. Steve Goldstein – a nationally renowned academic leader, physician and pediatric researcher – has been named vice chancellor for health affairs at the University of California, Irvine, effective Feb. 1, 2019. Goldstein will oversee and guide the development of the Susan and Henry Samueli College of Health Sciences, formed last year with a cornerstone gift of $200 million, the largest in UCI’s history.
Seven University of California, Irvine researchers in areas ranging from engineering and chemistry to sociology and anthropology have been named fellows of the American Association for the Advancement of Science, the world’s largest general scientific society.
The University of California, Irvine has been named by The Andrew W. Mellon Foundation as the national pilot site for an interdisciplinary team of researchers led by the School of Education to study approaches that will increase our understanding of what makes a liberal arts education so valuable.
Smoke from widespread fires in Indonesia in the summer and fall of 2015 hung heavily over major urban centers in Southeast Asia, causing adverse health effects for millions of people. The afflicted could not have known that the polluted air they were breathing contained carbon from plants that were alive during the Middle Ages.
The University of California, Irvine has been awarded a $5.4 million Gaining Early Awareness and Readiness for Undergraduate Programs partnership grant from the U.S. Department of Education to prepare middle school students for college access and success. The seven-year GEAR UP project will provide multiple academic activities and services for sixth- and seventh-graders in the Compton Unified School District that continue through high school and their freshman year in college.
Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for therapeutic actions of an African folk medicine used to treat a variety of illnesses and disorders including diabetes, pain, headaches, paralysis and epilepsy.
Amihai Glazer, UCI economics professor, is available for commentary on Amazon's HQ2 and 3 locations decision. He is a leading authority on relations between special interests and government, the author of five books on public policy and has provided industry insights for leading national media outlets
In a study published today in the journal Cell, University of California, Irvine researchers reported that they have accelerated and simplified directed evolution by having live cells do most of the heavy lifting. By inserting a specially engineered DNA replication system into yeast, the scientists were able to coax selected genes to rapidly and stably mutate and evolve as the host yeast cells reproduced.
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