Chronic pain occurs when receptors are drawn inside the nerve cell, out of the reach of pain medications. The discovery may lead to a more potent class of medications for chronic pain that has fewer side effects.
Researchers report that CRISPR-Cas9 gene-editing technology can introduce hundreds of unintended mutations into the genome.
Researchers at Columbia University found that women with preeclampsia have a higher stroke risk during pregnancy and postpartum if they have urinary tract infections, chronic high blood pressure, or blood disorders.
Recreational use of cannabis—including marijuana, hashish, and hash oil—increases the risk of gum disease, says a study by Columbia University dental researchers.
Spinal muscular atrophy is partly due to defects in the sensory neuron synapses that activate motor neurons. Symptoms may be reduced by improving synapse function.
New lung “organoids”—tiny 3-D structures that mimic features of a full-sized lung—have been created from human pluripotent stem cells by researchers at Columbia University Medical Center (CUMC). The team used the organoids to generate models of human lung diseases in a lab dish, which could be used to advance our understanding of a variety of respiratory diseases.
Researchers have discovered a molecular mechanism that reprograms tumor cells in patients with advanced prostate cancer, reducing their response to anti-androgen therapy. The findings, based on a study in mice, could help to determine which patients should avoid anti-androgen therapy and identify new treatments for people with advanced prostate cancer.
Columbia scientists observed how molecules that regulate chemical signaling in the brain interact with the AMPA receptor, governing brain function.
A study revealed that while dietary gluten does not increase heart disease risk in people without celiac disease, limiting whole grains may increase their heart risk.
Smoking counteracts the effect of a gene that normally protects against heart disease, according to a group of researchers.
Columbia University researchers have created a new tool, based on the principles of topology, to generate a roadmap of the many possible ways in which a stem cell may develop into specialized cells.
Glucoracle is a new app for people with type 2 diabetes that uses a personalized algorithm to predict the impact of particular foods on blood sugar levels.
Columbia University School of Nursing researchers found that utilizing patient electronic health records (EHR) to determine how far along a woman is in her pregnancy can support the automated delivery of content specifically targeted to their gestational age. The study found that Medicaid patients at the greatest risk of health disparities were able to get the information they needed to engage in better self-management during pregnancy.
A national survey from Columbia University School of Nursing finds that almost 40 percent of nursing students say they feel they need more instruction on preventing and controlling infection, especially in busy healthcare environments, despite believing that their nursing program emphasizes the importance of infection prevention. More than half of respondents also report observing breaches in prevention practices during clinical placements, yet have trouble addressing them because they feel unqualified or fear retaliation from others.
The Naomi Berrie Diabetes Center at Columbia University Medical Center has launched an initiative to study the relationship between the brain and metabolic disorders such as obesity and diabetes.
Columbia and NewYork-Presbyterian to participate in program led by the Foundation for the National Institutes of Health Biomarkers Consortium
The American Association of Dental Research presented the Jack Hein Public Service Award to Dean Christian S. Stohler of the Columbia University College of Dental Medicine
Dr. Panos Papapanou received the IADR Distinguished Scientist Award in Basic Research in Periodontal Disease for research on the epidemiology of periodontal diseases, their pathobiology, assessment of microbial and host-derived risk factors, as well as the diseases’ role as health stressor in heart disease and pregnancy complications.
Researchers at Columbia University Medical Center have discovered a common genetic variant that greatly affects normal brain aging in older adults. The discovery may point toward new targets for preventing or treating age-associated brain disorders such as Alzheimer’s disease.
Researchers at Columbia University Medical Center discovered that lipocalin 2, a hormone secreted by bone cells, suppresses appetite in mice. The study findings, which reveal a new mechanism for regulating food intake and blood sugar, could lead to the development of new treatments for obesity, type 2 diabetes, and other metabolic disorders.
Dr. Allan Formicola, who led the school for 23 years and chronicled its 100-year history, will receive the prestigious William J. Gies Award for Vision from ADEA. The College of Dental Medicine has received two previous Gies Awards.
Researchers at Columbia University Medical Center have identified genes that are linked to the underlying molecular defect in people with IgA nephropathy, an autoimmune kidney disease.
Columbia University Medical Centers names Muredach Reilly and Marwah Abdalla 2017 Katz Scholars.
Researchers have found that only 16 percent of heart attack survivors get the recommended amount of physical activity in the weeks after hospitalization, despite evidence that physical activity reduces the risk of having a second heart attack.
Bristol-Myers Squibb Company (NYSE:BMY) today announced that Columbia University Medical Center and Peter MacCallum Cancer Centre (Peter Mac) have joined the International Immuno-Oncology Network (II-ON).
An analysis of patient records reveals that, for many, an initial diagnosis of “acute kidney injury” using current clinical diagnostic methods may have been inaccurate.
Columbia University researchers have evidence that giving a small dose of ketamine one week before a psychologically traumatic event may help prevent PTSD. The study, in mice, may have implications for soldiers who are at risk for trauma and PTSD.
With funding from The Rockefeller Foundation, Columbia University’s Mailman School of Public Health today announces a Global Consortium on Climate and Health Education to share best scientific and educational practices and design model curricula on the health impacts of climate change for academic and non-academic audiences.
A research team led by Columbia University has discovered that loss of function of the CRKL gene causes kidney and urinary tract defects in people with DiGeorge syndrome, solving a 60-year-old medical mystery.
Researchers at Columbia University Medical Center have linked excess tau protein in the brain to the spatial disorientation that leads to wandering in many Alzheimer's disease patients. The findings, in mice, could lead to early diagnostic tests for Alzheimer's and point to treatments for this common and troubling symptom.
The Chapman Perelman Foundation has contributed $1 million to Columbia University Medical Center’s Department of Psychiatry to expand an initiative that provides mental health services to victims of domestic violence.
Researchers at Columbia University Medical Center and NewYork-Presbyterian showed that several genes implicated in rare forms of pediatric epilepsy also contribute to common forms of the disorder.
Collaboration will investigate the efficacy of a system biology approach to identifying treatment options for patients with advanced gastrointestinal stromal tumors.
Partnership aims to advance oral health through community-based research, education, and patient care.
Blood transfusions with the oldest blood available could be harmful for some patients, finds Columbia University researchers. The investigators recommend reducing the maximum blood storage limit from 6 to 5 weeks.
Columbia University researchers have created a user-friendly computational tool that rapidly predicts which genes are implicated in an individual’s cancer and recommends treatments.
Gastric tumors are started by specialized cells in the stomach that signal nerves to make more acetylcholine, according to a study in mice. But blocking nerve growth factor inhibits the formation of stomach tumors.
Children who get dental care through Medicaid have poorer oral health than privately insured kids who have the same amount of dental care.
Columbia University researchers have discovered an enzyme deficiency in the brain that is linked to Prader-Willi syndrome, a genetic condition that causes extreme hunger and severe obesity beginning in childhood.
In a Phase I study, 8 out of 12 patients with relapsed and/or chemotherapy refractory blood cancers responded to a combination of the chemotherapy drugs thioguanine and decitabine; some of the responders had relapsed after treatment with decitabine alone.
Columbia University researchers reported that people with schizophrenia who have difficulty hearing subtle changes in pitch may be helped with auditory training exercises and a drug that targets NMDA receptors in the brain.
Columbia University has awarded the 2016 Naomi Berrie Award for Outstanding Achievement in Diabetes Research to Peter Arner, MD, PhD, a Distinguished Professor in the Department of Medicine at the Karolinska Institute, whose studies on the turnover of fat tissue in the human body has revealed processes that contribute to obesity and diabetes.
Columbia University researchers slowed vision loss in mice with a form of retinitis pigmentosa by reprogramming the metabolism of photoreceptors in the retina.
Gene mutations that affect drug metabolism may explain higher hospitalization rates for some older adults taking multiple medications, according to researchers from Columbia University.
Scientists at Columbia University have identified a factor in liver cells that is responsible for turning AAFLD into a serious disease that can lead to liver failure.
Children from urban areas of New York City who engaged in vigorous daily exercise had greater exposure to black carbon, a traffic-related pollutant, than children who were less active, according to Columbia University researchers.
Patients who had a stent procedure or heart bypass surgery and continued with their prescribed medical therapy had significantly better outcomes than non-adherent patients, according to a new study.
Pregnancy was not found to raise the risk of stroke in older women, but the risk was significantly higher in young women, according to a study from Columbia University Medical Center and NewYork-Presbyterian.
Researchers at Columbia University Medical Center and the Data Science Institute at Columbia University have uncovered a potentially dangerous drug interaction using data science.
Researchers from Columbia College of Dental Medicine have identified stem cells in the jaw bone that can make new cartilage and repair damaged joints.
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